EA201270108A1 - Формирование полиспецифического t-клеточного ответа против вич у человека - Google Patents

Формирование полиспецифического t-клеточного ответа против вич у человека

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Publication number
EA201270108A1
EA201270108A1 EA201270108A EA201270108A EA201270108A1 EA 201270108 A1 EA201270108 A1 EA 201270108A1 EA 201270108 A EA201270108 A EA 201270108A EA 201270108 A EA201270108 A EA 201270108A EA 201270108 A1 EA201270108 A1 EA 201270108A1
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Eurasian Patent Office
Prior art keywords
polyspecific
human
formation
response against
cell response
Prior art date
Application number
EA201270108A
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English (en)
Inventor
Пол Чаплин
Ричард Николс
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Бавариан Нордик А/С
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Application filed by Бавариан Нордик А/С filed Critical Бавариан Нордик А/С
Publication of EA201270108A1 publication Critical patent/EA201270108A1/ru

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    • C12N2740/16334—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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Abstract

Изобретение относится к рекомбинантному модифицированному вирусу осповакцины Ankara (MVA), содержащему в вирусном геноме одну или более кассет экспрессии, экспрессирующих белки ВИЧ, выбранные из Gag, Pol, Tat, Vif, Vpu, Vpr, Rev и Nef, либо части или дериваты этих белков, или выбранные из Gag, Pol, Vpu, Vpr, Rev и Nef, либо части или дериваты этих белков, и предназначенному для использования в качестве препарата или вакцины для лечения или профилактики ВИЧ-инфекции и СПИДа.
EA201270108A 2009-10-08 2010-10-06 Формирование полиспецифического t-клеточного ответа против вич у человека EA201270108A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24964409P 2009-10-08 2009-10-08
EP10001264 2010-02-08
PCT/EP2010/006114 WO2011042180A1 (en) 2009-10-08 2010-10-06 Generation of a broad t-cell response in humans against hiv

Publications (1)

Publication Number Publication Date
EA201270108A1 true EA201270108A1 (ru) 2012-08-30

Family

ID=46396898

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201270108A EA201270108A1 (ru) 2009-10-08 2010-10-06 Формирование полиспецифического t-клеточного ответа против вич у человека

Country Status (11)

Country Link
US (1) US20120135032A1 (ru)
EP (1) EP2486138A1 (ru)
JP (1) JP2013507107A (ru)
KR (1) KR20120093941A (ru)
CN (1) CN102656271A (ru)
AU (1) AU2010305030A1 (ru)
CA (1) CA2767924A1 (ru)
EA (1) EA201270108A1 (ru)
MX (1) MX2012002531A (ru)
SG (1) SG178909A1 (ru)
WO (1) WO2011042180A1 (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2620446A1 (en) 2012-01-27 2013-07-31 Laboratorios Del Dr. Esteve, S.A. Immunogens for HIV vaccination
EP2968524A1 (en) * 2013-03-15 2016-01-20 Bavarian Nordic A/S Single high dose of mva induces a protective immune response in neonates and infants
MA40783A (fr) 2014-10-03 2017-08-08 Los Alamos Nat Security Llc Vaccins contre le vih comprenant un ou plusieurs antigènes episensus de population
FR3042121A1 (fr) 2015-10-08 2017-04-14 Jean-Marc Limacher Composition anti-tumorale
IL300730A (en) * 2016-07-08 2023-04-01 American Gene Tech Int Inc Pre-HIV vaccine and immunotherapy
WO2020264310A1 (en) * 2019-06-27 2020-12-30 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Compositions and methods for detecting hiv latency, treating hiv infection, and reversing hiv latency
CA3161633A1 (en) 2019-11-14 2021-05-20 Aelix Therapeutics, S.L. Dosage regimens for vaccines

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE787901A (fr) 1971-09-11 1972-12-18 Freistaat Bayern Represente Pa Vaccin antivariolique
ES2341429T3 (es) 1999-12-23 2010-06-21 Medical Research Council Mejoras en las respuestas inmunitarias al vih o relacionadas con las mismas.
CN1312171C (zh) * 2000-07-14 2007-04-25 宾夕法尼亚州立大学托管会 可编码hiv辅助蛋白的dna疫苗
NZ524661A (en) 2000-11-23 2005-03-24 Bavarian Nordic As Modified vaccinia ankara virus variant
NZ533302A (en) 2001-12-10 2005-11-25 Bavarian Nordic As Poxvirus containing formulations and process for preparing stable, poxvirus containing compositions containing a disaaccharide and a pharmaceutically acceptable polymer i.e. dextran or polyvinylpyrrolidon (PVP)
EA009525B1 (ru) 2002-05-16 2008-02-28 Бавариан Нордик А/С Рекомбинантный модифицированный вирус осповакцины ankara, содержащий ati-промотор вируса коровьей оспы, и способы применения вируса и промотора
EA007811B1 (ru) 2002-05-16 2007-02-27 Бавариан Нордик А/С Межгенные области, используемые в качестве инсерционных сайтов в геноме модифицированного вируса коровьей оспы анкара (mva)
US7501127B2 (en) * 2002-05-16 2009-03-10 Bavarian Nordic A/S Intergenic regions as novel sites for insertion of HIV DNA sequences in the genome of Modified Vaccinia virus Ankara
WO2003097675A1 (en) 2002-05-16 2003-11-27 Bavarian Nordic A/S Fusion protein of hiv regulatory/accessory proteins
CA2853335A1 (en) 2005-02-24 2006-11-23 Medical Research Council Hivcon: an hiv immunogen and uses thereof
ES2281252B1 (es) 2005-07-27 2009-02-16 Consejo Superior De Investigaciones Cientificas Vectores recombinantes basados en el virus modificado de ankara (mva) como vacunas preventivas y terapeuticas contra el sida.
EP2142212A2 (en) 2007-03-26 2010-01-13 International Aids Vaccine Initiative Method of elicting immune response with a modified mva viral hiv-1 vector
US8268327B2 (en) * 2007-04-27 2012-09-18 Bavarian Nordic A/S Immediate protection against pathogens via MVA
EP2222336A2 (en) * 2007-10-29 2010-09-01 GENimmune N.V. Methods and kits for inducing a ctl response using a prime boost regimen

Also Published As

Publication number Publication date
US20120135032A1 (en) 2012-05-31
MX2012002531A (es) 2012-04-11
SG178909A1 (en) 2012-04-27
JP2013507107A (ja) 2013-03-04
EP2486138A1 (en) 2012-08-15
AU2010305030A1 (en) 2012-05-10
KR20120093941A (ko) 2012-08-23
CN102656271A (zh) 2012-09-05
WO2011042180A1 (en) 2011-04-14
CA2767924A1 (en) 2011-04-14

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