EA201071280A1 - Производные хроманов как модуляторы trpv3 - Google Patents

Производные хроманов как модуляторы trpv3

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Publication number
EA201071280A1
EA201071280A1 EA201071280A EA201071280A EA201071280A1 EA 201071280 A1 EA201071280 A1 EA 201071280A1 EA 201071280 A EA201071280 A EA 201071280A EA 201071280 A EA201071280 A EA 201071280A EA 201071280 A1 EA201071280 A1 EA 201071280A1
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EA
Eurasian Patent Office
Prior art keywords
trpv3
chroman derivatives
modulators
disease
condition
Prior art date
Application number
EA201071280A
Other languages
English (en)
Inventor
Прасада Рао Лингам В.С.
Джавед Юсуф Кхатик
Абрахам Томас
Неелима Кхайраткар-Джоши
Видья Дж. Каттиге
Original Assignee
Гленмарк Фармасьютикалс С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Гленмарк Фармасьютикалс С.А. filed Critical Гленмарк Фармасьютикалс С.А.
Publication of EA201071280A1 publication Critical patent/EA201071280A1/ru

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    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D493/12—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains three hetero rings

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  • Health & Medical Sciences (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
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  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)

Abstract

Настоящее изобретение предусматривает производные хромана в качестве модуляторов ваниллоидных рецепторов преходящих потенциалов (TRPV). В частности, описанные здесь соединения пригодны для лечения или профилактики болезни, состояния и/или расстройства, модулируемого TRPV3. Также предусматриваются способы получения соединений, описанных тут, промежуточные соединения, используемые в их синтезе, их фармацевтические композиции и способы лечения или профилактики болезни, состояния и/или расстройства, модулируемых TRPV3.
EA201071280A 2008-06-17 2009-05-19 Производные хроманов как модуляторы trpv3 EA201071280A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IN1274MU2008 2008-06-17
US7860308P 2008-07-07 2008-07-07
PCT/IB2009/005641 WO2010004379A2 (en) 2008-06-17 2009-05-19 Chromane derivatives as trpv3 modulators

Publications (1)

Publication Number Publication Date
EA201071280A1 true EA201071280A1 (ru) 2012-05-30

Family

ID=41507489

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201071280A EA201071280A1 (ru) 2008-06-17 2009-05-19 Производные хроманов как модуляторы trpv3

Country Status (11)

Country Link
US (1) US8492568B2 (ru)
EP (1) EP2285794A4 (ru)
JP (1) JP2011529855A (ru)
AU (1) AU2009269720A1 (ru)
CA (1) CA2728405A1 (ru)
EA (1) EA201071280A1 (ru)
GE (1) GEP20125709B (ru)
MX (1) MX2010011762A (ru)
NZ (1) NZ595780A (ru)
UA (1) UA104861C2 (ru)
WO (1) WO2010004379A2 (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013003121A2 (pt) * 2010-08-10 2016-06-28 Abbvie Inc moduladores de trpv3
US9012651B2 (en) 2011-03-24 2015-04-21 Abbvie Inc. TRPV3 modulators
US8772500B2 (en) 2011-10-24 2014-07-08 Abbvie Inc. TRPV3 modulators
EP2919773A4 (en) * 2012-11-19 2016-11-02 Univ Columbia METHOD FOR THE TREATMENT OF KERATINOCYTE-MEDIATED LESIONS
CN112480018B (zh) * 2020-11-30 2023-06-20 中国药科大学 一种trpv3小分子变构抑制剂及其制备方法

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Also Published As

Publication number Publication date
WO2010004379A2 (en) 2010-01-14
EP2285794A2 (en) 2011-02-23
EP2285794A4 (en) 2012-08-29
AU2009269720A2 (en) 2012-05-31
MX2010011762A (es) 2011-02-03
GEP20125709B (en) 2012-12-10
US8492568B2 (en) 2013-07-23
WO2010004379A3 (en) 2011-11-17
JP2011529855A (ja) 2011-12-15
UA104861C2 (ru) 2014-03-25
AU2009269720A1 (en) 2012-01-19
US20110098316A1 (en) 2011-04-28
NZ595780A (en) 2013-07-26
CA2728405A1 (en) 2010-01-14

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