EA201070806A1 - Состав медленного высвобождения на основе ассоциации гликогена и альгината - Google Patents

Состав медленного высвобождения на основе ассоциации гликогена и альгината

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Publication number
EA201070806A1
EA201070806A1 EA201070806A EA201070806A EA201070806A1 EA 201070806 A1 EA201070806 A1 EA 201070806A1 EA 201070806 A EA201070806 A EA 201070806A EA 201070806 A EA201070806 A EA 201070806A EA 201070806 A1 EA201070806 A1 EA 201070806A1
Authority
EA
Eurasian Patent Office
Prior art keywords
glycogen
alginate
association
slow
finging
Prior art date
Application number
EA201070806A
Other languages
English (en)
Other versions
EA018975B1 (ru
Inventor
Винченцо Руссо
Элиза Либерати
Никола Каццолла
Леонардо Маркитто
Лорелла Раньи
Original Assignee
Ацьенде Кимике Рьюните Анджелини Франческо A.K.P.A.Ф. С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ацьенде Кимике Рьюните Анджелини Франческо A.K.P.A.Ф. С.П.А. filed Critical Ацьенде Кимике Рьюните Анджелини Франческо A.K.P.A.Ф. С.П.А.
Publication of EA201070806A1 publication Critical patent/EA201070806A1/ru
Publication of EA018975B1 publication Critical patent/EA018975B1/ru

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2009Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1611Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1652Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/02Nasal agents, e.g. decongestants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Abstract

Настоящее изобретение относится к фармацевтическому составу контролируемого высвобождения, содержащему по меньшей мере один активный ингредиент, диспергированный в матрице, включающей по меньшей мере один эксципиент медленного высвобождения, содержащий ассоциацию по меньшей мере одного гликогена и по меньшей мере одного альгината с солями щелочно-земельных металлов, и к способу его приготовления. Изобретение также относится к эксципиенту медленного высвобождения, содержащему ассоциацию по меньшей мере одного гликогена и по меньшей мере одного альгината с солями щелочно-земельных металлов, и к способу его получения, и его применению для приготовления фармацевтических составов медленного высвобождения.
EA201070806A 2007-12-28 2008-12-23 Состав медленного высвобождения на основе ассоциации гликогена и альгината EA018975B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07425828 2007-12-28
PCT/EP2008/068256 WO2009083561A1 (en) 2007-12-28 2008-12-23 A slow-release formulation based on an association of glycogen and alginate

Publications (2)

Publication Number Publication Date
EA201070806A1 true EA201070806A1 (ru) 2010-12-30
EA018975B1 EA018975B1 (ru) 2013-12-30

Family

ID=39522216

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070806A EA018975B1 (ru) 2007-12-28 2008-12-23 Состав медленного высвобождения на основе ассоциации гликогена и альгината

Country Status (21)

Country Link
US (1) US8840923B2 (ru)
EP (1) EP2234607B1 (ru)
JP (1) JP5416716B2 (ru)
KR (1) KR101561571B1 (ru)
CN (1) CN101909608B (ru)
AR (1) AR069960A1 (ru)
AT (1) ATE518530T1 (ru)
AU (1) AU2008342571B2 (ru)
BR (1) BRPI0821454B8 (ru)
CA (1) CA2708400C (ru)
DK (1) DK2234607T3 (ru)
EA (1) EA018975B1 (ru)
ES (1) ES2369868T3 (ru)
GE (1) GEP20125636B (ru)
HK (1) HK1145284A1 (ru)
IL (1) IL206124A (ru)
PL (1) PL2234607T3 (ru)
PT (1) PT2234607E (ru)
SI (1) SI2234607T1 (ru)
UA (1) UA98684C2 (ru)
WO (1) WO2009083561A1 (ru)

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MX2011007817A (es) 2009-01-23 2011-09-21 A F S P A Aziende Chimichi Riunite Angelini Francesco A C R Formulacion farmaceutica o alimenticia de liberacion controlada y proceso para su preparacion.
PT2461701E (pt) * 2009-08-03 2016-06-06 Acraf Formulação alimentar compreendendo glicogénio
EP2988725A4 (en) * 2013-04-26 2016-03-09 Mirexus Biotechnologies Inc MONOPERATED GLYCOGEN AND PHYTOGLYCOGEN NANOTEHICLES AND USE THEREOF AS ADDITIVES IN COSMETIC PREPARATIONS, MEDICAMENTS AND FOOD PRODUCTS
CN106137977B (zh) * 2015-04-28 2019-12-13 浙江普利药业有限公司 海参多糖肠溶微丸及其制备方法
US11865099B2 (en) 2015-07-17 2024-01-09 Laboratori Baldacci S.P.A. Product based on iron bis-glycinate chelate and alginic acid and/or water-soluble salts thereof, formulations thereof, and pharmaceutical uses thereof
ITUB20152290A1 (it) 2015-07-17 2017-01-17 Laboratori Baldacci Spa Prodotto a base di ferro bisglicinato chelato e acido alginico e/o suoi sali idrosolubili, sue formulazioni ed suoi usi farmaceutici
US20190038542A1 (en) * 2016-02-08 2019-02-07 Mirexus Biotechnologies Inc. Moisturizing personal care compositions comprising monodisperse phytoglycogen nanoparticles and a further polysaccharide

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US3640741A (en) * 1970-02-24 1972-02-08 Hollister Inc Composition containing gel
DE2062715C3 (de) * 1970-12-19 1974-03-21 Efeka Friedrich & Kaufmann Arzneimittelfabrik, 3000 Hannover Verfahren zur Herstellung von oral applizierbaren Arzneimittelzubereitungen mit protrahierter Wirkstoffabgabe und Arzneimittelzubereitung
ATE66143T1 (de) * 1985-01-11 1991-08-15 Abbott Lab Feste zubereitung mit langsamer freisetzung.
JPS62178505A (ja) 1986-02-03 1987-08-05 Maruzen Kasei Kk 化粧料
JPS63290809A (ja) 1987-05-25 1988-11-28 Noebia:Kk 口唇用化粧料
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
IT1255488B (it) 1992-08-04 1995-11-06 Angelini Francesco Ist Ricerca Polisaccaridi del glicogeno
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US5807575A (en) 1997-02-14 1998-09-15 Rougier Inc. Manufacture of cross-linked amylose useful as a excipient for control release of active compounds
IT1298758B1 (it) 1998-03-19 2000-02-02 Angelini Ricerche Spa Soluzione umettante e lubrificante per uso oftalmico
US6607748B1 (en) * 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
WO2002041876A1 (en) 2000-11-22 2002-05-30 Lupin Limited Pharmaceutical composition for controlled release of an active ingredient
EP1620076A4 (en) * 2003-04-25 2010-08-25 Kos Life Sciences Inc HIGH SUPERPOREOUS HYDROGEL FORMATION
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US20070099820A1 (en) * 2005-10-19 2007-05-03 Smartcells, Inc. Polymer-drug conjugates

Also Published As

Publication number Publication date
GEP20125636B (en) 2012-09-10
CN101909608B (zh) 2013-01-23
AU2008342571A1 (en) 2009-07-09
JP2011519820A (ja) 2011-07-14
ES2369868T3 (es) 2011-12-07
AR069960A1 (es) 2010-03-03
EP2234607A1 (en) 2010-10-06
WO2009083561A1 (en) 2009-07-09
JP5416716B2 (ja) 2014-02-12
IL206124A0 (en) 2010-11-30
CN101909608A (zh) 2010-12-08
BRPI0821454A2 (pt) 2015-06-16
UA98684C2 (ru) 2012-06-11
EA018975B1 (ru) 2013-12-30
KR20100099728A (ko) 2010-09-13
AU2008342571B2 (en) 2014-03-13
PT2234607E (pt) 2011-09-30
PL2234607T3 (pl) 2011-12-30
DK2234607T3 (da) 2011-11-21
SI2234607T1 (sl) 2011-11-30
BRPI0821454B8 (pt) 2021-05-25
IL206124A (en) 2013-01-31
US20100255083A1 (en) 2010-10-07
BRPI0821454B1 (pt) 2020-01-28
ATE518530T1 (de) 2011-08-15
CA2708400A1 (en) 2009-07-09
EP2234607B1 (en) 2011-08-03
CA2708400C (en) 2016-02-02
US8840923B2 (en) 2014-09-23
HK1145284A1 (en) 2011-04-15
KR101561571B1 (ko) 2015-10-19

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Legal Events

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU