EA200870546A1 - Стабильные водные суспензии - Google Patents

Стабильные водные суспензии

Info

Publication number
EA200870546A1
EA200870546A1 EA200870546A EA200870546A EA200870546A1 EA 200870546 A1 EA200870546 A1 EA 200870546A1 EA 200870546 A EA200870546 A EA 200870546A EA 200870546 A EA200870546 A EA 200870546A EA 200870546 A1 EA200870546 A1 EA 200870546A1
Authority
EA
Eurasian Patent Office
Prior art keywords
stable water
suspension
water suspensions
polyvinylpyrrolidone
glycerin
Prior art date
Application number
EA200870546A
Other languages
English (en)
Other versions
EA015301B1 (ru
Inventor
Уилли Блэйкли
Луиза Рейнолдс
Лиллиан Кроми
Original Assignee
Норбрук Лэборетериз Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38170964&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200870546(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0610058A external-priority patent/GB0610058D0/en
Priority claimed from GB0610246A external-priority patent/GB0610246D0/en
Application filed by Норбрук Лэборетериз Лимитед filed Critical Норбрук Лэборетериз Лимитед
Priority claimed from PCT/GB2007/001700 external-priority patent/WO2007135362A2/en
Publication of EA200870546A1 publication Critical patent/EA200870546A1/ru
Publication of EA015301B1 publication Critical patent/EA015301B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Inorganic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • General Preparation And Processing Of Foods (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Водная фармацевтическая суспензия, содержащая: (i) по меньшей мере одно нестероидное противовоспалительное лекарственное средство; (ii) водную буферную систему; (iii) ксантановую смолу; (iv) поливинилпирролидон и (v) глицерин, где суспензия не содержит прежелатинизированного крахмала, аминополикарбоновой кислоты, микрокристаллической целлюлозы, гидроксипропилметилцеллюлозы, полиоксиэтиленсорбитан моноолеата, двуокиси кремния и модификаторов вкуса, выбранных из группы, состоящей из подсластителей-наполнителей, подсластителей с интенсивным вкусом ароматических добавок и их смесей.
EA200870546A 2006-05-19 2007-05-10 Стабильные водные суспензии EA015301B1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0610058A GB0610058D0 (en) 2006-05-19 2006-05-19 Stable aqueous suspension
GB0610246A GB0610246D0 (en) 2006-05-23 2006-05-23 Stable aqueous suspension
GB0708375A GB2438287A (en) 2006-05-19 2007-04-30 Stable aqueous suspension
PCT/GB2007/001700 WO2007135362A2 (en) 2006-05-19 2007-05-10 Stable aqueous suspension having palatable taste

Publications (2)

Publication Number Publication Date
EA200870546A1 true EA200870546A1 (ru) 2009-04-28
EA015301B1 EA015301B1 (ru) 2011-06-30

Family

ID=38170964

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200870546A EA015301B1 (ru) 2006-05-19 2007-05-10 Стабильные водные суспензии

Country Status (16)

Country Link
US (1) US9399013B2 (ru)
JP (2) JP5391063B2 (ru)
KR (1) KR101452721B1 (ru)
AT (1) ATE446740T1 (ru)
CR (1) CR10429A (ru)
DE (1) DE602007003026D1 (ru)
DK (1) DK2034958T3 (ru)
EA (1) EA015301B1 (ru)
ES (1) ES2335622T3 (ru)
GB (1) GB2438287A (ru)
IL (1) IL194244A (ru)
MX (1) MX2008011775A (ru)
NZ (1) NZ572380A (ru)
PE (1) PE20080233A1 (ru)
PT (1) PT2034958E (ru)
SI (1) SI2034958T1 (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6050564B2 (ja) * 2010-03-11 2016-12-21 テイカ製薬株式会社 フィルム状製剤
GB201117858D0 (en) * 2011-10-17 2011-11-30 Norbrook Lab Ltd Paste
FI126442B (en) * 2011-11-01 2016-12-15 Valio Oy Liquid enzyme preparation and process for its preparation
EP3673897A4 (en) * 2017-08-24 2021-05-05 Jiangsu Hengrui Medicine Co., Ltd. INJECTABLE PHARMACEUTICAL COMPOSITION WITH MELOXICAM AND METHOD FOR MANUFACTURING IT
KR102145022B1 (ko) * 2018-08-14 2020-08-14 동아제약 주식회사 이부프로펜의 현탁액 조성물 및 투여 제형
US20210093642A1 (en) * 2019-09-26 2021-04-01 Cadila Healthcare Limited STABLE AQUEOUS PARENTERAL SOLUTIONS OF NONSTEROIDAL ANTI-INFLAMMATORY DRUGS (NSAIDs)

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2756113A1 (de) 1977-12-16 1979-06-21 Thomae Gmbh Dr K Neue 4-hydroxy-2h-1,2-benzothiazin- 3-carboxamid-1,1-dioxide, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
CA2033634A1 (en) 1990-01-12 1991-07-13 Takao Ikariya Method of manufacturing aromatic urethane
JPH0714872B2 (ja) * 1990-02-06 1995-02-22 昭和薬品化工株式会社 シロップ剤組成物
US5183829A (en) 1991-09-27 1993-02-02 Applied Analytical Industries, Inc. Oral liquid compositions of non-steroidal anti-inflammatory drugs
US5272137A (en) 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
KR940003066A (ko) 1992-07-07 1994-02-19 김주용 콘택홀 접속방법
CA2121435C (en) 1993-04-16 2002-01-22 Sheila M. Ratnaraj Aqueous pharmaceutical suspension and process for preparation thereof
US6093420A (en) * 1996-07-08 2000-07-25 Edward Mendell Co., Inc. Sustained release matrix for high-dose insoluble drugs
IT1286496B1 (it) 1996-11-20 1998-07-15 Leetrim Ltd Dublin Composizione farmaceutica orale ad attivita' antipiretica,analgesica ed antiinfiammatoria
JP4234666B2 (ja) * 1997-03-28 2009-03-04 エーザイ・アール・アンド・ディー・マネジメント株式会社 苦味等を隠蔽した経口薬剤
EP0945131A1 (de) 1998-03-27 1999-09-29 Boehringer Ingelheim Pharma KG Perorale Wirkstoff-Suspension
US6184220B1 (en) 1998-03-27 2001-02-06 Boehringer Ingelheim Pharma Kg Oral suspension of pharmaceutical substance
US6268356B1 (en) 1998-04-20 2001-07-31 Pharmaceutical Resources, Inc. Flocculated suspension of megestrol acetate
JP4073121B2 (ja) * 1998-08-28 2008-04-09 エーザイ・アール・アンド・ディー・マネジメント株式会社 薬物の苦味等を軽減した組成物
JP2000119198A (ja) * 1998-10-16 2000-04-25 Eisai Co Ltd 苦味等の隠蔽されたホスフォジエステラーゼ阻害剤含有経口製剤
EP1165042B1 (fr) 1999-04-06 2005-02-02 Ethypharm Suspension pharmaceutique buvable d'ibuprofene
US7101572B2 (en) 2001-12-07 2006-09-05 Unilab Pharmatech, Ltd. Taste masked aqueous liquid pharmaceutical composition
CA2486553C (en) 2002-06-17 2012-01-10 Taro Pharmaceuticals U.S.A., Inc. Ibuprofen suspension
US8512727B2 (en) * 2003-03-03 2013-08-20 Alkermes Pharma Ireland Limited Nanoparticulate meloxicam formulations
US20050069590A1 (en) * 2003-09-30 2005-03-31 Buehler Gail K. Stable suspensions for medicinal dosages
PL1824493T3 (pl) * 2004-12-06 2009-01-30 Janssen Pharmaceutica Nv Zawiesina zawierająca meloksykam do podawania doustnego

Also Published As

Publication number Publication date
ES2335622T3 (es) 2010-03-30
SI2034958T1 (sl) 2010-02-26
CR10429A (es) 2008-12-01
JP5391063B2 (ja) 2014-01-15
DK2034958T3 (da) 2010-03-15
GB2438287A (en) 2007-11-21
US20090186883A1 (en) 2009-07-23
JP2009537495A (ja) 2009-10-29
KR20090023607A (ko) 2009-03-05
US9399013B2 (en) 2016-07-26
NZ572380A (en) 2011-10-28
PT2034958E (pt) 2010-01-04
EA015301B1 (ru) 2011-06-30
PE20080233A1 (es) 2008-04-10
ATE446740T1 (de) 2009-11-15
IL194244A (en) 2011-12-29
DE602007003026D1 (de) 2009-12-10
MX2008011775A (es) 2008-10-01
JP2013241422A (ja) 2013-12-05
KR101452721B1 (ko) 2014-10-21
GB0708375D0 (en) 2007-06-06

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): BY

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU