EA200870222A1 - Кондиционированная композиция крови и способ ее получения - Google Patents
Кондиционированная композиция крови и способ ее полученияInfo
- Publication number
- EA200870222A1 EA200870222A1 EA200870222A EA200870222A EA200870222A1 EA 200870222 A1 EA200870222 A1 EA 200870222A1 EA 200870222 A EA200870222 A EA 200870222A EA 200870222 A EA200870222 A EA 200870222A EA 200870222 A1 EA200870222 A1 EA 200870222A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- blood
- obtaining
- composition
- conditioned
- modified container
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1825—Fibroblast growth factor [FGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1841—Transforming growth factor [TGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1858—Platelet-derived growth factor [PDGF]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/191—Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
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- A—HUMAN NECESSITIES
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2006—IL-1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2026—IL-4
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/204—IL-6
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2066—IL-10
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/20—Interleukins [IL]
- A61K38/2086—IL-13 to IL-16
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/30—Insulin-like growth factors (Somatomedins), e.g. IGF-1, IGF-2
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/02—Blood transfusion apparatus
- A61M1/0209—Multiple bag systems for separating or storing blood components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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- A61P37/02—Immunomodulators
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
Abstract
Данное изобретение относится к способу получения кондиционированных композиций крови, которые содержат индуцированные факторы, а также к кондиционированным композициям крови, изготавливаемым с помощью способа, и к его применению для лечения или профилактики заболевания тела человека или животного.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102006005016A DE102006005016A1 (de) | 2006-02-03 | 2006-02-03 | Konditionierte Blutzusammensetzung und Verfahren zu deren Herstellung |
PCT/EP2007/000903 WO2007090569A1 (de) | 2006-02-03 | 2007-02-02 | Konditionierte blutzusammensetzung und verfahren zu deren herstellung |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200870222A1 true EA200870222A1 (ru) | 2008-12-30 |
EA014435B1 EA014435B1 (ru) | 2010-12-30 |
Family
ID=37965046
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200870222A EA014435B1 (ru) | 2006-02-03 | 2007-02-02 | Кондиционированная композиция крови и способ ее получения |
Country Status (24)
Country | Link |
---|---|
US (1) | US20090047242A1 (ru) |
EP (2) | EP1984006B1 (ru) |
JP (1) | JP2009525297A (ru) |
KR (1) | KR20080100425A (ru) |
CN (1) | CN101378768A (ru) |
AT (1) | ATE446100T1 (ru) |
AU (1) | AU2007213996A1 (ru) |
BR (1) | BRPI0707360A2 (ru) |
CA (1) | CA2640002A1 (ru) |
CY (1) | CY1109735T1 (ru) |
DE (2) | DE102006005016A1 (ru) |
DK (1) | DK1984006T3 (ru) |
EA (1) | EA014435B1 (ru) |
ES (1) | ES2335446T3 (ru) |
HK (1) | HK1125835A1 (ru) |
HR (1) | HRP20090684T1 (ru) |
MX (1) | MX2008009807A (ru) |
PL (1) | PL1984006T3 (ru) |
PT (1) | PT1984006E (ru) |
RS (1) | RS51247B (ru) |
SI (1) | SI1984006T1 (ru) |
UA (1) | UA90048C2 (ru) |
WO (1) | WO2007090569A1 (ru) |
ZA (1) | ZA200805975B (ru) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7832566B2 (en) | 2002-05-24 | 2010-11-16 | Biomet Biologics, Llc | Method and apparatus for separating and concentrating a component from a multi-component material including macroparticles |
US20060278588A1 (en) | 2002-05-24 | 2006-12-14 | Woodell-May Jennifer E | Apparatus and method for separating and concentrating fluids containing multiple components |
US8034014B2 (en) | 2007-03-06 | 2011-10-11 | Biomet Biologics, Llc | Angiogenesis initation and growth |
US20080269762A1 (en) * | 2007-04-25 | 2008-10-30 | Biomet Manufacturing Corp. | Method and device for repair of cartilage defects |
US8753690B2 (en) | 2008-02-27 | 2014-06-17 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
WO2009108890A1 (en) | 2008-02-27 | 2009-09-03 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
DE102008028684A1 (de) * | 2008-06-17 | 2009-12-24 | Kopetzky, Robert, Dr. | Blutbeutel |
US8460227B2 (en) * | 2008-11-17 | 2013-06-11 | Arthrex, Inc. | Cytokine concentration system |
AU2010237191A1 (en) | 2009-04-07 | 2011-11-03 | Velin-Pharma A/S | Method and device for treatment of conditions associated with inflammation or undesirable activation of the immune system |
US20110052561A1 (en) * | 2009-08-27 | 2011-03-03 | Biomet Biologics,LLC | Osteolysis treatment |
AU2010292486B2 (en) | 2009-08-27 | 2014-08-07 | Biomet Biologics, Llc | Implantable device for production of interleukin-1 receptor antagonist |
AU2010294197C9 (en) * | 2009-09-10 | 2018-09-13 | Velin-Pharma A/S | Method for the preparation of micro-RNA and its therapeutic application |
DE202009017772U1 (de) | 2009-12-10 | 2011-04-21 | Orthogen Ag | Kombinationspräparate mit Cytokin-Antagonist und Corticosteroid |
AU2011296356B2 (en) | 2010-09-03 | 2015-07-09 | Biomet Biologics, Llc | Methods and compositions for delivering interleukin-1 receptor antagonist |
DE102010042356A1 (de) * | 2010-10-12 | 2012-04-12 | Henke-Sass, Wolf Gmbh | Behälter für die Herstellung einer konditionierten Blutzusammensetzung |
US9011846B2 (en) | 2011-05-02 | 2015-04-21 | Biomet Biologics, Llc | Thrombin isolated from blood and blood fractions |
US9205110B2 (en) | 2012-07-18 | 2015-12-08 | Arthrex, Inc. | Enhanced autologous growth factor production and delivery system |
DE102012019088A1 (de) * | 2012-09-28 | 2014-04-03 | Orthogen Ag | Antibakterielle Arzneimittelpräparate |
DK2956150T3 (da) | 2013-02-12 | 2021-11-01 | Lacerta Tech Inc | Serumfraktion af trombocyt-rig fibrin |
US9878011B2 (en) | 2013-03-15 | 2018-01-30 | Biomet Biologics, Llc | Treatment of inflammatory respiratory disease using biological solutions |
US20140271589A1 (en) | 2013-03-15 | 2014-09-18 | Biomet Biologics, Llc | Treatment of collagen defects using protein solutions |
US9895418B2 (en) | 2013-03-15 | 2018-02-20 | Biomet Biologics, Llc | Treatment of peripheral vascular disease using protein solutions |
US10208095B2 (en) | 2013-03-15 | 2019-02-19 | Biomet Manufacturing, Llc | Methods for making cytokine compositions from tissues using non-centrifugal methods |
US10143725B2 (en) | 2013-03-15 | 2018-12-04 | Biomet Biologics, Llc | Treatment of pain using protein solutions |
US9758806B2 (en) | 2013-03-15 | 2017-09-12 | Biomet Biologics, Llc | Acellular compositions for treating inflammatory disorders |
US9950035B2 (en) | 2013-03-15 | 2018-04-24 | Biomet Biologics, Llc | Methods and non-immunogenic compositions for treating inflammatory disorders |
EP2829278A1 (de) * | 2013-07-23 | 2015-01-28 | Scientific BioTech GmbH | Serum zur Behnandlung von Krankheiten |
WO2015081253A1 (en) | 2013-11-26 | 2015-06-04 | Biomet Biologics, Llc | Methods of mediating macrophage phenotypes |
WO2015085348A1 (en) * | 2013-12-09 | 2015-06-18 | Cytokine Medical Australia Pty Ltd | Apparatus for producing therapeutically active proteins in blood and uses thereof |
US10441635B2 (en) | 2014-11-10 | 2019-10-15 | Biomet Biologics, Llc | Methods of treating pain using protein solutions |
US9763800B2 (en) | 2015-03-18 | 2017-09-19 | Biomet C. V. | Implant configured for hammertoe and small bone fixation |
CN108348548A (zh) * | 2016-08-17 | 2018-07-31 | 奥索根股份公司 | 抗衰老药物制剂 |
EP3613424A1 (en) * | 2018-08-23 | 2020-02-26 | Orthogen AG | Novel methods for the production of pharmaceutical agents |
DE102021124752A1 (de) * | 2021-09-24 | 2023-03-30 | Ad Lentus GmbH | Autologes Therapeutikum und Verfahren zur Herstellung desselben |
CN114146096B (zh) * | 2021-11-25 | 2024-04-02 | 成都清科生物科技有限公司 | 一种富含细胞因子的条件血清的制备方法及应用 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4244437A1 (de) * | 1992-12-29 | 1994-07-28 | Horst Dr Med Kief | Verfahren zur Gewinnung körpereigener Zytokine |
DE19903876B4 (de) * | 1999-02-01 | 2006-09-28 | Orthogen Gentechnologie Gmbh | Verfahren zur in-vitro-Bildung und Anreicherung von Interleukin-1 Rezeptor-Antagonisten |
US20020081324A1 (en) * | 2002-01-22 | 2002-06-27 | Twine Rebecca Wright | Method of treating aging skin and wrinkles using a combination of growth factors that is commercially prepared or derived from one's own blood |
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2006
- 2006-02-03 DE DE102006005016A patent/DE102006005016A1/de not_active Withdrawn
-
2007
- 2007-02-02 PT PT07711428T patent/PT1984006E/pt unknown
- 2007-02-02 CA CA002640002A patent/CA2640002A1/en not_active Abandoned
- 2007-02-02 PL PL07711428T patent/PL1984006T3/pl unknown
- 2007-02-02 ZA ZA200805975A patent/ZA200805975B/xx unknown
- 2007-02-02 BR BRPI0707360-7A patent/BRPI0707360A2/pt not_active IP Right Cessation
- 2007-02-02 US US12/162,022 patent/US20090047242A1/en not_active Abandoned
- 2007-02-02 RS RSP-2010/0012A patent/RS51247B/sr unknown
- 2007-02-02 DK DK07711428.8T patent/DK1984006T3/da active
- 2007-02-02 MX MX2008009807A patent/MX2008009807A/es not_active Application Discontinuation
- 2007-02-02 EP EP07711428A patent/EP1984006B1/de not_active Revoked
- 2007-02-02 SI SI200730130T patent/SI1984006T1/sl unknown
- 2007-02-02 CN CNA2007800044614A patent/CN101378768A/zh active Pending
- 2007-02-02 AU AU2007213996A patent/AU2007213996A1/en not_active Abandoned
- 2007-02-02 EP EP09013177A patent/EP2156841A1/de not_active Withdrawn
- 2007-02-02 DE DE502007001793T patent/DE502007001793D1/de active Active
- 2007-02-02 WO PCT/EP2007/000903 patent/WO2007090569A1/de active Application Filing
- 2007-02-02 KR KR1020087018622A patent/KR20080100425A/ko not_active Application Discontinuation
- 2007-02-02 AT AT07711428T patent/ATE446100T1/de active
- 2007-02-02 EA EA200870222A patent/EA014435B1/ru not_active IP Right Cessation
- 2007-02-02 ES ES07711428T patent/ES2335446T3/es active Active
- 2007-02-02 UA UAA200810851A patent/UA90048C2/ru unknown
- 2007-02-02 JP JP2008552751A patent/JP2009525297A/ja not_active Withdrawn
-
2009
- 2009-04-28 HK HK09103942.4A patent/HK1125835A1/xx not_active IP Right Cessation
- 2009-12-23 HR HR20090684T patent/HRP20090684T1/hr unknown
-
2010
- 2010-01-15 CY CY20101100046T patent/CY1109735T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
MX2008009807A (es) | 2008-09-26 |
RS51247B (sr) | 2010-12-31 |
ATE446100T1 (de) | 2009-11-15 |
EP1984006A1 (de) | 2008-10-29 |
UA90048C2 (ru) | 2010-03-25 |
DE102006005016A1 (de) | 2007-08-16 |
WO2007090569A1 (de) | 2007-08-16 |
ES2335446T3 (es) | 2010-03-26 |
SI1984006T1 (sl) | 2010-02-26 |
EP1984006B1 (de) | 2009-10-21 |
WO2007090569A8 (de) | 2008-02-28 |
DE502007001793D1 (de) | 2009-12-03 |
CY1109735T1 (el) | 2014-09-10 |
PT1984006E (pt) | 2010-01-20 |
CN101378768A (zh) | 2009-03-04 |
HRP20090684T1 (hr) | 2010-02-28 |
BRPI0707360A2 (pt) | 2011-05-03 |
HK1125835A1 (en) | 2009-08-21 |
AU2007213996A1 (en) | 2007-08-16 |
CA2640002A1 (en) | 2007-08-16 |
PL1984006T3 (pl) | 2010-03-31 |
US20090047242A1 (en) | 2009-02-19 |
KR20080100425A (ko) | 2008-11-18 |
DK1984006T3 (da) | 2010-03-01 |
EA014435B1 (ru) | 2010-12-30 |
ZA200805975B (en) | 2010-08-25 |
JP2009525297A (ja) | 2009-07-09 |
EP2156841A1 (de) | 2010-02-24 |
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