EA200870153A1 - Композиция и способ ее использования - Google Patents
Композиция и способ ее использованияInfo
- Publication number
- EA200870153A1 EA200870153A1 EA200870153A EA200870153A EA200870153A1 EA 200870153 A1 EA200870153 A1 EA 200870153A1 EA 200870153 A EA200870153 A EA 200870153A EA 200870153 A EA200870153 A EA 200870153A EA 200870153 A1 EA200870153 A1 EA 200870153A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- vulvovaginal
- composition
- effective against
- amount effective
- lipid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4172—Imidazole-alkanecarboxylic acids, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
- A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
- A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Endocrinology (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Фармацевтическая композиция содержит (а) метронидазол в эффективном против бактерий количестве, и (b) противогрибковое вещество в эффективном против грибков количестве, содержащая бутоконазол или его фармацевтически приемлемую соль или сложный эфир. Композиция адаптирована для применения в стандартном дозированном количестве на вульвовагинальную поверхность и обладает по меньшей мере одной нелипидной внутренней фазой и по меньшей мере одной липидной внешней фазой, которая биоадгезивна к вульвовагинальной поверхности. Композиция применима для нанесения на вульвовагинальную поверхность для лечения смешенного бактериального вагиноза и вульвовагинальной кандидозной инфекции.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75680506P | 2006-01-05 | 2006-01-05 | |
PCT/US2006/062652 WO2007079389A2 (en) | 2006-01-05 | 2006-12-28 | Composition and method of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
EA200870153A1 true EA200870153A1 (ru) | 2008-12-30 |
Family
ID=38093536
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200870153A EA200870153A1 (ru) | 2006-01-05 | 2006-12-28 | Композиция и способ ее использования |
Country Status (11)
Country | Link |
---|---|
US (1) | US20070224226A1 (ru) |
EP (1) | EP1968543A2 (ru) |
JP (1) | JP2009522360A (ru) |
KR (1) | KR20080091793A (ru) |
CN (1) | CN101374501A (ru) |
AU (1) | AU2006332518A1 (ru) |
BR (1) | BRPI0620908A2 (ru) |
CA (1) | CA2635986A1 (ru) |
EA (1) | EA200870153A1 (ru) |
IL (1) | IL192564A0 (ru) |
WO (1) | WO2007079389A2 (ru) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010079373A1 (en) * | 2009-01-09 | 2010-07-15 | EGIS GYOGYSZERGYAR, Nyilvánosan, Müködö | Improved pharmaceutical formulation |
EP2725904A4 (en) | 2011-06-28 | 2014-12-10 | Medicis Pharmaceutical Corp | HIGH-DOSE MUCOADHESIVE AQUEOUS METRONIZOUS MELTRONIDAZE GEL FORMULATIONS AND USE THEREOF FOR TREATING BACTERIAL VAGINOSIS |
EP3013368A1 (en) | 2013-06-25 | 2016-05-04 | Mission Pharmacal Company | Novel formulations for the treatment of vaginal disorders |
FR3094636B1 (fr) * | 2019-04-05 | 2022-07-29 | Soc Dexploitation De Produits Pour Les Industries Chimiques Seppic | Composition pharmaceutique à usage topique comprenant au moins une substance antifongique locale azolée |
CN110218742B (zh) * | 2019-06-13 | 2021-03-02 | 北京双因生物科技有限公司 | 一种病毒感染细胞用试剂及其应用 |
CN113476610A (zh) * | 2021-08-13 | 2021-10-08 | 云南中医药大学 | 甘油衍生物与抗真菌药物组成的抗真菌药物组合物 |
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US4342741A (en) * | 1981-04-27 | 1982-08-03 | Dental Chemical Co., Ltd. | Dentifrice compositions |
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IT1253711B (it) * | 1991-12-17 | 1995-08-23 | Alfa Wassermann Spa | Formulazioni farmaceutiche vaginali contenenti rifaximin e loro uso nel trattamento delle infezioni vaginali |
IL101387A (en) * | 1992-03-26 | 1999-11-30 | Pharmos Ltd | Emulsion with enhanced topical and/or transdermal systemic effect utilizing submicron oil droplets |
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EP0665733B1 (en) * | 1992-10-21 | 2003-05-07 | Gynetech Laboratories, Inc. | Vaginal sponge delivery system |
US6113921A (en) * | 1993-03-23 | 2000-09-05 | Pharmos Corp. | Topical and transdermal delivery system utilizing submicron oil spheres |
ES2182841T3 (es) * | 1993-04-19 | 2003-03-16 | Inst Advanced Skin Res Inc | Preparacion en microemulsion conteniendo una substancia dificilmente absorbible. |
GB9318641D0 (en) * | 1993-09-08 | 1993-10-27 | Edko Trading Representation | Compositions |
JP3566739B2 (ja) * | 1993-09-30 | 2004-09-15 | 三省製薬株式会社 | 皮膚外用剤の安定化方法 |
US6228383B1 (en) * | 1994-03-03 | 2001-05-08 | Gs Development Ab | Use of fatty acid esters as bioadhesive substances |
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-
2006
- 2006-12-28 EA EA200870153A patent/EA200870153A1/ru unknown
- 2006-12-28 US US11/617,180 patent/US20070224226A1/en not_active Abandoned
- 2006-12-28 CA CA002635986A patent/CA2635986A1/en not_active Abandoned
- 2006-12-28 WO PCT/US2006/062652 patent/WO2007079389A2/en active Application Filing
- 2006-12-28 JP JP2008549526A patent/JP2009522360A/ja active Pending
- 2006-12-28 BR BRPI0620908-4A patent/BRPI0620908A2/pt not_active Application Discontinuation
- 2006-12-28 CN CNA2006800529428A patent/CN101374501A/zh active Pending
- 2006-12-28 EP EP06849002A patent/EP1968543A2/en not_active Withdrawn
- 2006-12-28 AU AU2006332518A patent/AU2006332518A1/en not_active Abandoned
- 2006-12-28 KR KR1020087019100A patent/KR20080091793A/ko not_active Application Discontinuation
-
2008
- 2008-07-01 IL IL192564A patent/IL192564A0/en unknown
Also Published As
Publication number | Publication date |
---|---|
WO2007079389A2 (en) | 2007-07-12 |
WO2007079389A3 (en) | 2007-12-27 |
US20070224226A1 (en) | 2007-09-27 |
BRPI0620908A2 (pt) | 2011-11-29 |
CA2635986A1 (en) | 2007-07-12 |
KR20080091793A (ko) | 2008-10-14 |
CN101374501A (zh) | 2009-02-25 |
AU2006332518A1 (en) | 2007-07-12 |
JP2009522360A (ja) | 2009-06-11 |
IL192564A0 (en) | 2009-02-11 |
EP1968543A2 (en) | 2008-09-17 |
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