WO2009038106A1 - アラニルチロシンを含有する経口剤 - Google Patents

アラニルチロシンを含有する経口剤 Download PDF

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Publication number
WO2009038106A1
WO2009038106A1 PCT/JP2008/066808 JP2008066808W WO2009038106A1 WO 2009038106 A1 WO2009038106 A1 WO 2009038106A1 JP 2008066808 W JP2008066808 W JP 2008066808W WO 2009038106 A1 WO2009038106 A1 WO 2009038106A1
Authority
WO
WIPO (PCT)
Prior art keywords
oral administration
alanyltyrosine
administration drug
drug containing
tyrosine
Prior art date
Application number
PCT/JP2008/066808
Other languages
English (en)
French (fr)
Inventor
Aya Ozaki
Koji Morishita
Original Assignee
Kyowa Hakko Bio Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Bio Co., Ltd. filed Critical Kyowa Hakko Bio Co., Ltd.
Publication of WO2009038106A1 publication Critical patent/WO2009038106A1/ja

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05Dipeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychiatry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

 本発明は、アラニルチロシンまたはその塩を有効成分として含有する、即効性血中チロシン濃度上昇型経口剤を提供する。該経口剤は、生体内のチロシン含量を高め、速やかにチロシンの摂取効果が得られる。
PCT/JP2008/066808 2007-09-19 2008-09-18 アラニルチロシンを含有する経口剤 WO2009038106A1 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-242955 2007-09-19
JP2007242955 2007-09-19

Publications (1)

Publication Number Publication Date
WO2009038106A1 true WO2009038106A1 (ja) 2009-03-26

Family

ID=40467916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066808 WO2009038106A1 (ja) 2007-09-19 2008-09-18 アラニルチロシンを含有する経口剤

Country Status (1)

Country Link
WO (1) WO2009038106A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019059356A1 (ja) * 2017-09-25 2019-03-28 花王株式会社 高吸収型経口チロシン製剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MAHER,TJ ET AL.: "Use of parenteral dipeptides to increase serum tyrosine levels and to enhance catecholamine-mediated neurotransmission.", J. PHARM. SCI., vol. 79, no. 8, August 1990 (1990-08-01), pages 685 - 687 *
REINSTEIN,DK ET AL.: "Dietary tyrosine suppresses the rise in plasma corticosterone following acute stress in rats.", LIFE SCI., vol. 37, no. 23, 9 December 1985 (1985-12-09), pages 2157 - 2163 *

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2019059356A1 (ja) * 2017-09-25 2019-03-28 花王株式会社 高吸収型経口チロシン製剤
JP2019059678A (ja) * 2017-09-25 2019-04-18 花王株式会社 高吸収型経口チロシン製剤
JP7008452B2 (ja) 2017-09-25 2022-01-25 花王株式会社 高吸収型経口チロシン製剤
US11278586B2 (en) 2017-09-25 2022-03-22 Kao Corporation Highly absorbable oral tyrosine formulation

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