EA200700994A1 - Обратные мицеллы для доставки катионов металлов, включающие в себя диглицерид и фитостерол, и способ их получения - Google Patents

Обратные мицеллы для доставки катионов металлов, включающие в себя диглицерид и фитостерол, и способ их получения

Info

Publication number
EA200700994A1
EA200700994A1 EA200700994A EA200700994A EA200700994A1 EA 200700994 A1 EA200700994 A1 EA 200700994A1 EA 200700994 A EA200700994 A EA 200700994A EA 200700994 A EA200700994 A EA 200700994A EA 200700994 A1 EA200700994 A1 EA 200700994A1
Authority
EA
Eurasian Patent Office
Prior art keywords
reverse micelles
phytosterol
delivery
receiving
metal cations
Prior art date
Application number
EA200700994A
Other languages
English (en)
Other versions
EA012210B1 (ru
Inventor
Жан-Клод Морель
Original Assignee
Медзис Фарма
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Медзис Фарма filed Critical Медзис Фарма
Publication of EA200700994A1 publication Critical patent/EA200700994A1/ru
Publication of EA012210B1 publication Critical patent/EA012210B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Nutrition Science (AREA)
  • Biophysics (AREA)
  • Dispersion Chemistry (AREA)
  • Neurology (AREA)
  • Polymers & Plastics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Food Science & Technology (AREA)
  • Mycology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • AIDS & HIV (AREA)
  • Emergency Medicine (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Psychology (AREA)

Abstract

Настоящее изобретение относится к способу получения обратных мицелл, содержащих стеролы, ацилглицеролы и металлические соли, и к полученным этим методом обратным мицеллам. Их лучше использовать в фармацевтической и диетической областях техники.
EA200700994A 2004-11-02 2005-11-02 Обратные мицеллы для доставки катионов металлов, включающие в себя диглицерид и фитостерол, и способ их получения EA012210B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04025987A EP1652512A1 (en) 2004-11-02 2004-11-02 Reverse micelle composition for delivery of metal cations comprising a diglyceride and a phytosterol and method of preparation
PCT/IB2005/003605 WO2006048773A1 (en) 2004-11-02 2005-11-02 Reverse micelle composition for delivery of metal cations comprising a diglyceride and a phytosterol and method of preparation

Publications (2)

Publication Number Publication Date
EA200700994A1 true EA200700994A1 (ru) 2007-10-26
EA012210B1 EA012210B1 (ru) 2009-08-28

Family

ID=34927200

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700994A EA012210B1 (ru) 2004-11-02 2005-11-02 Обратные мицеллы для доставки катионов металлов, включающие в себя диглицерид и фитостерол, и способ их получения

Country Status (17)

Country Link
US (1) US9173838B2 (ru)
EP (2) EP1652512A1 (ru)
JP (1) JP4975631B2 (ru)
CN (1) CN101102751B (ru)
AT (1) ATE483454T1 (ru)
AU (1) AU2005300253B2 (ru)
CA (1) CA2584684C (ru)
DE (1) DE602005024036D1 (ru)
DK (1) DK1807048T3 (ru)
EA (1) EA012210B1 (ru)
ES (1) ES2353804T3 (ru)
HK (1) HK1108368A1 (ru)
IL (1) IL182756A (ru)
PL (1) PL1807048T3 (ru)
PT (1) PT1807048E (ru)
WO (1) WO2006048773A1 (ru)
ZA (1) ZA200704286B (ru)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1652513A1 (en) * 2004-11-02 2006-05-03 Denderah Pharm Sa Reverse micelles based on sterols and acylglycerols and therapeutic uses thereof
WO2011117333A2 (en) 2010-03-24 2011-09-29 Medesis Pharma Reverse micelle system comprising metal ions and use thereof
BRPI1000970A2 (pt) * 2010-04-07 2011-11-29 Fundacao Arnaldo Vieira De Carvalho composição farmacêutica para o tratamento da doença de alzheimer, processo para sua obtenção e uso
WO2012007387A1 (en) * 2010-07-13 2012-01-19 Medesis Pharma Low- dose lithium for the treatment of neurodegenerative disorders
EP3319588A1 (en) * 2015-07-09 2018-05-16 Medesis Pharma In situ preparation of cyano-bridged metal nanop articles within a biocompatible reverse micellar system
BR112021000121A2 (pt) * 2018-07-06 2021-04-06 Medesis Pharma Tratamento e prevenção de lesões devido a exposição à radiação

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252333A (en) * 1987-04-27 1993-10-12 Scotia Holdings Plc Lithium salt-containing pharmaceutical compositions
FR2658816A1 (fr) * 1990-02-27 1991-08-30 Adir Nouveaux sels de metaux alcalinoterreux d'oxa-polyacides leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
FR2729957B1 (fr) 1995-01-31 1997-12-05 Maurel Sante Complexes organometalliques a base de sitosterols et d'acylglycerols et compositions pharmaceutiques et produits dietetiques en contenant.
FR2750606B1 (fr) * 1996-07-03 1999-01-29 Maurel Sante Complexes organometalliques a base de sitosterols et de diglycerides et compositions pharmaceutiques en contenant
JPH119988A (ja) * 1997-06-26 1999-01-19 Advanced Sukin Res Kenkyusho:Kk 油中水型マイクロエマルション
JPH1129464A (ja) * 1997-07-07 1999-02-02 Advanced Sukin Res Kenkyusho:Kk コレステロールを添加する油中水型マイクロエマルション
WO2000057721A2 (en) * 1999-03-26 2000-10-05 Akesis Pharmaceuticals, Inc. Edible solids for treatment of glucose metabolism disorders
US6623765B1 (en) * 2000-08-01 2003-09-23 University Of Florida, Research Foundation, Incorporated Microemulsion and micelle systems for solubilizing drugs
US6365176B1 (en) * 2000-08-08 2002-04-02 Functional Foods, Inc. Nutritional supplement for patients with type 2 diabetes mellitus for lipodystrophy
SK9472003A3 (en) * 2001-01-25 2003-12-02 Unilever Nv An edible water-in-oil microemulsion, process for the preparation thereof, a food product containing same and use such a microemulsion
US20030113366A1 (en) * 2001-12-14 2003-06-19 Macgregor Alexander Reverse-micellar delivery system for controlled transportation and enhanced absorption of agents
EP1452175A1 (en) * 2003-02-28 2004-09-01 Medesis Pharma S.A. Manganese based organometallic complexes, pharmaceutical compositions and dietetic products
CN1457773A (zh) * 2003-06-02 2003-11-26 乐益 治疗糖尿病的双胍钒络合物颗粒剂和/或胶囊剂及其用途
EP1652513A1 (en) * 2004-11-02 2006-05-03 Denderah Pharm Sa Reverse micelles based on sterols and acylglycerols and therapeutic uses thereof

Also Published As

Publication number Publication date
EP1652512A1 (en) 2006-05-03
IL182756A0 (en) 2007-07-24
JP2008519026A (ja) 2008-06-05
PL1807048T3 (pl) 2011-03-31
CN101102751B (zh) 2011-08-24
US9173838B2 (en) 2015-11-03
ZA200704286B (en) 2008-09-25
JP4975631B2 (ja) 2012-07-11
PT1807048E (pt) 2010-11-29
ES2353804T3 (es) 2011-03-07
EP1807048B1 (en) 2010-10-06
AU2005300253B2 (en) 2010-09-09
HK1108368A1 (en) 2008-05-09
US20090087477A1 (en) 2009-04-02
WO2006048773A1 (en) 2006-05-11
IL182756A (en) 2011-02-28
CN101102751A (zh) 2008-01-09
AU2005300253A1 (en) 2006-05-11
ATE483454T1 (de) 2010-10-15
EA012210B1 (ru) 2009-08-28
CA2584684A1 (en) 2006-05-11
DE602005024036D1 (de) 2010-11-18
EP1807048A1 (en) 2007-07-18
CA2584684C (en) 2013-07-02
DK1807048T3 (da) 2011-01-10

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU