EA200700840A1 - Новый продукт, способ и промежуточные продукты получения производных азетидина - Google Patents

Новый продукт, способ и промежуточные продукты получения производных азетидина

Info

Publication number
EA200700840A1
EA200700840A1 EA200700840A EA200700840A EA200700840A1 EA 200700840 A1 EA200700840 A1 EA 200700840A1 EA 200700840 A EA200700840 A EA 200700840A EA 200700840 A EA200700840 A EA 200700840A EA 200700840 A1 EA200700840 A1 EA 200700840A1
Authority
EA
Eurasian Patent Office
Prior art keywords
new product
intermediate products
azetidine derivatives
obtain azetidine
derivatives
Prior art date
Application number
EA200700840A
Other languages
English (en)
Other versions
EA011408B1 (ru
Inventor
Стефан Мютти
Мишель Лавинь
Люк Грондар
Жоэль Мальпар
Йорг Рике-Цапп
Вероник Крок
Original Assignee
Авентис Фарма С.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Авентис Фарма С.А. filed Critical Авентис Фарма С.А.
Publication of EA200700840A1 publication Critical patent/EA200700840A1/ru
Publication of EA011408B1 publication Critical patent/EA011408B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Immunology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Новый способ получения производных азетидина, таких как N-{1-[бис-(4-хлорфенил)метил]азетидин-3-ил}-N-хинол-6-илметилсульфонамид и его дихлоргидрат и N-{1-[бис-(4-хлорфенил)метил]азетидин-3-ил}-N-(3,5-дифторфенил)метилсульфонамид.
EA200700840A 2004-10-14 2005-10-10 Новый продукт, способ и промежуточные продукты получения производных азетидина EA011408B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0410844A FR2876688B1 (fr) 2004-10-14 2004-10-14 Nouveau produit, procede et intermediaires de preparation de derives d'azetidine
PCT/FR2005/002490 WO2006040465A2 (fr) 2004-10-14 2005-10-10 Nouveau produit, procede et intermediaires de preparation de derives d'azetidine

Publications (2)

Publication Number Publication Date
EA200700840A1 true EA200700840A1 (ru) 2007-08-31
EA011408B1 EA011408B1 (ru) 2009-02-27

Family

ID=34954419

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200700840A EA011408B1 (ru) 2004-10-14 2005-10-10 Новый продукт, способ и промежуточные продукты получения производных азетидина

Country Status (21)

Country Link
US (1) US7687493B2 (ru)
EP (1) EP1805167A2 (ru)
JP (1) JP2008516932A (ru)
KR (1) KR20070063544A (ru)
CN (1) CN101039931A (ru)
AR (1) AR051390A1 (ru)
AU (1) AU2005293454A1 (ru)
BR (1) BRPI0516507A (ru)
CA (1) CA2583992A1 (ru)
EA (1) EA011408B1 (ru)
EC (1) ECSP077332A (ru)
FR (1) FR2876688B1 (ru)
IL (1) IL181904A0 (ru)
MA (1) MA29513B1 (ru)
MX (1) MX2007003923A (ru)
NO (1) NO20072192L (ru)
SG (1) SG155193A1 (ru)
TN (1) TNSN07097A1 (ru)
TW (1) TW200630358A (ru)
WO (1) WO2006040465A2 (ru)
ZA (1) ZA200702528B (ru)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113045539B (zh) * 2021-03-30 2021-12-07 苏州大学 2-(4,4-二氯-1-(8-喹啉基)-2-氮杂环丁基)羧酸酯衍生物的制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8709887D0 (en) * 1987-04-27 1987-06-03 Univ Alberta Alkyl azodicarboxylates
US5530134A (en) * 1994-09-06 1996-06-25 Synphar Laboratories Inc. Synthesis of anabaseine, salts and derivatives thereof
US6355631B1 (en) * 2000-03-03 2002-03-12 Aventis Pharma S.A. Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation
FR2805817B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Compositions pharmaceutiques contenant des derives d'azetidine, les nouveaux derives d'azetidine et leur preparation
BRPI0113146B8 (pt) * 2000-08-10 2021-05-25 Mitsubishi Pharma Corp "derivados de prolina e composição farmacêutica que os compreende".
CN1874991A (zh) * 2003-08-29 2006-12-06 小野药品工业株式会社 能够结合s1p受体的化合物及其药物用途

Also Published As

Publication number Publication date
EA011408B1 (ru) 2009-02-27
MX2007003923A (es) 2007-06-07
SG155193A1 (en) 2009-09-30
KR20070063544A (ko) 2007-06-19
ZA200702528B (en) 2008-07-30
FR2876688A1 (fr) 2006-04-21
AR051390A1 (es) 2007-01-10
MA29513B1 (fr) 2008-06-02
TW200630358A (en) 2006-09-01
ECSP077332A (es) 2007-04-26
TNSN07097A1 (fr) 2008-06-02
AU2005293454A1 (en) 2006-04-20
US20070270463A1 (en) 2007-11-22
WO2006040465A2 (fr) 2006-04-20
IL181904A0 (en) 2007-07-04
CN101039931A (zh) 2007-09-19
BRPI0516507A (pt) 2008-09-16
US7687493B2 (en) 2010-03-30
FR2876688B1 (fr) 2007-03-16
CA2583992A1 (fr) 2006-04-20
JP2008516932A (ja) 2008-05-22
WO2006040465A3 (fr) 2006-08-10
NO20072192L (no) 2007-04-27
EP1805167A2 (fr) 2007-07-11

Similar Documents

Publication Publication Date Title
HUP0300237A2 (hu) N-Piperidino-5-(klórfenil)-1-(2,4-diklórfenil)-4-metil-pirazol-3-karboxamid alkalmazása dohányzás abbahagyásának megkönnyítésére szolgáló gyógyszerkészítmény előállítására
TNSN06409A1 (en) Novel fluoroglycoside derivatives of pyrazoles, medicaments containing these compounds, and the use thereof
PT1713475E (pt) Derivados de 4,5-diidro-1h-pirazol 1,3,5-trissubstituído tendo atividade antagonística a cb1
HK1081199A1 (en) Process and intermediates for the preparation of (1r,2s,5s)-6,6-dimethyl-3- azabicyclo [3,1,0] hexane-2-carboxylates or salts thereof
PL1758852T3 (pl) Podstawione związki cyklopentenu
NO20064078L (no) Substituerte azetidinsammensetninger, deres fremstilling og anvendelse som medikamenter
PL378168A1 (pl) Dihydropterydynony, sposoby ich wytwarzania i ich zastosowanie w postaci leków
EA200700096A1 (ru) Производные 2-карбамид-4-фенилтиазола, способ их получения и их применение в терапии
MXPA05012680A (es) Indoles novedosos de 3-azufre sustituidos.
MXPA05012362A (es) Yodopirazolilcarboxanilidas.
NO20082096L (no) Azaindol-2-karboksamidderivativer
TW200745039A (en) Isotopically substituted pantoprazole
NO20064351L (no) Caspaseinhibitorer og anvendelser derav
CY1112727T1 (el) Παραγωγα κυκλοβουτυλ αμινης βενζοθειαζολης και η χρηση αυτων ως προσδετες των υποδοχεων ισταμινης-3
DE50202504D1 (de) Neue 4-aminofuropyrimidine und ihre verwendung
RS98704A (en) New pharmaceutical compositions containing flibanserin polymorpha
MXPA05013751A (es) Procedimiento e intermediarios para la preparacion de 3-(amino)-3-ciclobutilmetil-2-hidroxi-propionamida o sus sales.
NO20080750L (no) (Indol-3-YL)-heterocykelderivater som agonister av cannabinoid CB1 reseptor
WO2007047431A3 (en) Sulfonyl-substituted aryl compounds as modulators of peroxisome proliferator activated receptors
WO2004106307A3 (fr) Nouveaux derives d’imidazoles, leur preparation et leur utilisation en tant que medicament
EA200700840A1 (ru) Новый продукт, способ и промежуточные продукты получения производных азетидина
TNSN07115A1 (fr) Procede et intermediaires de preparation de derives de n-(1-benzhydryl-azetidin-3-yl)-n-phenyl-methylsulfonamide
UA81664C2 (ru) Производные дифенилмочевины и их применение, как блокаторов хлоридных каналов
EA200300771A1 (ru) Новая соль бензоилгуанидина
MXPA04001951A (es) Coniosulfuros y sus derivados, procesos para prepararlos, y su uso como farmaceuticos.

Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU