EA200501206A1 - Производные от сурвивина пептиды и их применение - Google Patents
Производные от сурвивина пептиды и их применениеInfo
- Publication number
- EA200501206A1 EA200501206A1 EA200501206A EA200501206A EA200501206A1 EA 200501206 A1 EA200501206 A1 EA 200501206A1 EA 200501206 A EA200501206 A EA 200501206A EA 200501206 A EA200501206 A EA 200501206A EA 200501206 A1 EA200501206 A1 EA 200501206A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- application
- derivations
- survivin peptides
- survivin
- tumor
- Prior art date
Links
- 102000000763 Survivin Human genes 0.000 title abstract 2
- 108010002687 Survivin Proteins 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 3
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 210000000265 leukocyte Anatomy 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4747—Apoptosis related proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
- A61K39/001148—Regulators of development
- A61K39/00115—Apoptosis related proteins, e.g. survivin or livin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464448—Regulators of development
- A61K39/46445—Apoptosis related proteins, e.g. survivin or livin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/464838—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4738—Cell cycle regulated proteins, e.g. cyclin, CDC, INK-CCR
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/31—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterized by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/38—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/48—Blood cells, e.g. leukemia or lymphoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
- A61K2239/46—Indexing codes associated with cellular immunotherapy of group A61K39/46 characterised by the cancer treated
- A61K2239/57—Skin; melanoma
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
Abstract
Рестриктированные по МНС классу I, производные опухолеассоциированного антигена - сурвивина, которые способны связываться с молекулами HLA класса I при высокой аффинности, способны элиситировать INF-γ-продуцирующие клетки в популяции PBL пациентов, страдающих раком, и способны к in situ обнаружению цитотоксических Т-клеток в опухолевой ткани, терапевтическая и диагностическая композиция, включающая пептид, и ее применение.Отчет о международном поиске был опубликован 2004.10.28.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/354,090 US20040210035A1 (en) | 2002-01-30 | 2003-01-30 | Survivin-derived peptides and use thereof |
US10/715,417 US7892559B2 (en) | 2002-01-30 | 2003-11-19 | Survivin-derived peptides and use thereof |
PCT/DK2004/000062 WO2004067023A2 (en) | 2003-01-30 | 2004-01-30 | Survivin-derived peptides and use thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
EA200501206A1 true EA200501206A1 (ru) | 2006-02-24 |
EA008026B1 EA008026B1 (ru) | 2007-02-27 |
Family
ID=32829435
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200501206A EA008026B1 (ru) | 2003-01-30 | 2004-01-30 | Производные от сурвивина пептиды и их применение |
Country Status (16)
Country | Link |
---|---|
US (4) | US7892559B2 (ru) |
EP (5) | EP2857034B1 (ru) |
JP (1) | JP5121143B2 (ru) |
CN (2) | CN1767848B (ru) |
AT (3) | ATE454159T1 (ru) |
AU (1) | AU2004208469B2 (ru) |
CA (1) | CA2513104C (ru) |
DE (3) | DE602004032483D1 (ru) |
EA (1) | EA008026B1 (ru) |
ES (2) | ES2339193T3 (ru) |
HK (2) | HK1087335A1 (ru) |
MX (1) | MXPA05008128A (ru) |
NO (1) | NO333213B1 (ru) |
NZ (1) | NZ541510A (ru) |
PT (3) | PT2092938E (ru) |
WO (1) | WO2004067023A2 (ru) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040210035A1 (en) * | 2002-01-30 | 2004-10-21 | Straten Eivind Per Thor | Survivin-derived peptides and use thereof |
US7892559B2 (en) * | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
KR101284237B1 (ko) | 2003-11-19 | 2013-07-09 | 수르벡 에이피에스 | Bcl-2 패밀리에 속한 단백질들, 그들의 단편들 및 암 환자에 대한 그들의 용도 |
JP4602006B2 (ja) * | 2004-06-29 | 2010-12-22 | 独立行政法人科学技術振興機構 | サバイビン由来のhla−a24結合性癌抗原ペプチド |
EP2657338B1 (en) * | 2005-01-25 | 2015-07-08 | NEC Corporation | HLA-binding peptide, and DNA fragment and recombinant vector coding for said HLA-binding peptide |
AU2006209951B2 (en) | 2005-02-04 | 2011-04-14 | Survac Aps | Survivin peptide vaccine |
AU2011203536B2 (en) * | 2005-02-04 | 2012-11-15 | Survac Aps | Survivin peptide vaccine |
AU2011203535B2 (en) * | 2005-02-04 | 2012-10-11 | Survac Aps | Survivin peptide vaccine |
US20060276423A1 (en) * | 2005-04-18 | 2006-12-07 | Rachel Altura | Survivin-directed RNA interference-compositions and methods |
US20070104689A1 (en) * | 2005-09-27 | 2007-05-10 | Merck Patent Gmbh | Compositions and methods for treating tumors presenting survivin antigens |
FR2891462B1 (fr) * | 2005-09-30 | 2009-10-16 | Commissariat Energie Atomique | Epitopes t cd4+ de la survivine et leurs applications |
IL172896A0 (en) * | 2005-12-29 | 2006-06-11 | Yeda Res & Dev | Cxcr4 inhibition |
WO2009012460A1 (en) * | 2007-07-19 | 2009-01-22 | Health Research, Inc. | Survivin peptides as cancer vaccines |
US8580269B2 (en) | 2007-07-19 | 2013-11-12 | Health Research, Inc. | Survivin peptides for autoimmune therapies |
JP5546448B2 (ja) * | 2008-03-31 | 2014-07-09 | 株式会社バイオイミュランス | MHCクラスII分子に提示されるサーバイビン(Survivin)の部分ペプチドとその利用法 |
ES2532896T5 (es) * | 2008-05-14 | 2018-03-20 | Immatics Biotechnologies Gmbh | Péptidos del MHC de clase II novedosos y potentes derivados de survivina y neurocan |
TWI526219B (zh) | 2008-06-19 | 2016-03-21 | 腫瘤療法 科學股份有限公司 | Cdca1抗原決定位胜肽及含此胜肽的疫苗 |
EP2172211B1 (en) * | 2008-10-01 | 2014-12-03 | Immatics Biotechnologies GmbH | Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers |
US9023802B2 (en) | 2009-12-14 | 2015-05-05 | Immatics Biotechnologies Gmbh | HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
CA2821582A1 (en) | 2010-12-14 | 2012-06-21 | Immatics Biotechnologies Gmbh | Hla-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
BR112013023978B1 (pt) * | 2011-03-21 | 2021-09-08 | Atlantic Cancer Research Institute | Polipeptídeo com afinidade por proteínas de choque térmico e seu uso em diagnóstico de doença infecciosa, produção de resposta imune e tratamento de câncer, bem como ácido nucleico, composição e método de fracionamento de substância para pesquisa ou análise clínica de amostra biológica |
EP2854842A4 (en) * | 2012-05-25 | 2016-11-02 | Agenus Inc | IDENTIFICATION OF BREAST CANCER CLASS I MHC PHOSPHOPEPTIDE ANTIGENS USING SHLA TECHNOLOGY AND COMPLEMENTARY ENRICHMENT STRATEGIES |
EP2872532A4 (en) | 2012-07-10 | 2016-04-13 | Oncotherapy Science Inc | CDCA1-EPITOPPEPTIDES FOR TH1 CELLS AND VACCINES THEREWITH |
ES2702622T3 (es) | 2013-03-27 | 2019-03-04 | Immunovaccine Technologies Inc | Método para mejorar la eficacia de una vacuna de survivina en el tratamiento de cáncer |
JP6697386B2 (ja) | 2013-11-22 | 2020-05-20 | ザ ボード オブ トラスティーズ オブ ザ ユニバーシティ オブ イリノイ | 改変された高親和性ヒトt細胞受容体 |
AU2015289644A1 (en) | 2014-07-15 | 2017-02-02 | Juno Therapeutics, Inc. | Engineered cells for adoptive cell therapy |
JP2018509384A (ja) | 2015-01-06 | 2018-04-05 | イミューノヴァクシーン テクノロジーズ インコーポレイテッドImmunovaccine Technologies Inc. | リピドa模倣体、調製方法、及びその使用 |
GB201507030D0 (en) | 2015-04-24 | 2015-06-10 | Immatics Biotechnologies Gmbh | Immunotherapy against lung cancers, in particular NSCLC |
US20180162913A1 (en) * | 2015-05-01 | 2018-06-14 | Immunovaccine Technologies Inc. | Methods for potentiating an immune response using depot-forming and non-depot-forming vaccines |
MA42895A (fr) | 2015-07-15 | 2018-05-23 | Juno Therapeutics Inc | Cellules modifiées pour thérapie cellulaire adoptive |
JP6989134B2 (ja) | 2015-11-18 | 2022-01-05 | イミューノヴァクシーン テクノロジーズ インコーポレイテッドImmunovaccine Technologies Inc. | ポリi:cポリヌクレオチドアジュバント及び脂質系アジュバントを含むアジュバント系及び水を含まないワクチン組成物 |
GB201604755D0 (en) * | 2016-03-21 | 2016-05-04 | Vaxeal Res Sas | Immunogenic compositions |
KR20190057345A (ko) | 2016-09-21 | 2019-05-28 | 아말 테라퓨틱스 에스에이 | 암 치료를 위한, 세포 투과 펩타이드, 멀티 에피토프 및 tlr 펩타이드 작용제를 포함하는 융합체 |
WO2018065625A2 (en) | 2016-10-07 | 2018-04-12 | Enterome | Immunogenic compounds for cancer therapy |
JP7116278B2 (ja) | 2016-10-07 | 2022-08-10 | エンテローム エスエー | 癌治療のための免疫原性化合物 |
CN110049774A (zh) | 2016-10-07 | 2019-07-23 | 恩特罗姆公司 | 肿瘤相关抗原表位的小型生物群序列变体 |
KR102591136B1 (ko) | 2017-03-03 | 2023-10-17 | 트레오스 바이오 리미티드 | 집단 기반 면역원성 펩타이드 확인 플랫폼 |
JP6993677B2 (ja) * | 2017-11-08 | 2022-01-13 | 学校法人日本医科大学 | 犬におけるがんの予防、がんの治療またはがんの転移の予防のためのがんペプチドワクチン |
LT3773689T (lt) * | 2018-04-11 | 2023-01-25 | Enterome S.A. | Antigeniniai peptidai, skirti vėžio prevencijai ir gydymui |
SG11202101888YA (en) | 2018-09-04 | 2021-03-30 | Treos Bio Ltd | Peptide vaccines |
FR3087448B1 (fr) | 2018-10-23 | 2023-10-13 | Pdc Line Pharma | Lignee pdc modifiee pour secreter une cytokine |
US20220125903A1 (en) * | 2018-11-19 | 2022-04-28 | Immunovaccine Technologies Inc. | Methods for improving the efficacy of a survivin therapeutic in the treatment of tumors |
CN111440246B (zh) * | 2020-04-16 | 2022-03-18 | 成都仕康美生物科技有限公司 | 靶向HLA-B的嵌合抗原受体、编码基因、CAR-Tregs细胞及其制备方法、用途 |
KR20230044133A (ko) * | 2021-09-24 | 2023-04-03 | 주식회사 차백신연구소 | 종양 연관 항원으로부터 유래된 펩타이드 및 리포펩타이드와 면역활성물질로 구성되는 아쥬번트를 포함하는 항암 백신 조성물 및 이의 용도 |
CN115477686B (zh) * | 2022-09-22 | 2024-01-30 | 北海黑珍珠海洋生物科技有限公司 | 一种具有美白功效的珍珠贝活性肽及其应用 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5342774A (en) | 1991-05-23 | 1994-08-30 | Ludwig Institute For Cancer Research | Nucleotide sequence encoding the tumor rejection antigen precursor, MAGE-1 |
US6037135A (en) * | 1992-08-07 | 2000-03-14 | Epimmune Inc. | Methods for making HLA binding peptides and their uses |
ATE378406T1 (de) | 1992-08-31 | 2007-11-15 | Ludwig Inst Cancer Res | Vom mage-3-gen en abgeleitetes und von hla-a1 präsentiertes, isoliertes nonapeptid und dessen anwendungen |
US5514539A (en) * | 1993-06-29 | 1996-05-07 | The United States Of America As Represented By The Department Of Health And Human Services | Nucleotide and deduced amino acid sequences of the envelope 1 gene of 51 isolates of hepatitis C virus and the use of reagents derived from these sequences in diagnostic methods and vaccines |
US6096313A (en) | 1996-02-09 | 2000-08-01 | Ludwig Institute For Cancer Research | Compositions containing immunogenic molecules and granulocyte-macrophage colony stimulating factor, as an adjuvant |
AU736587B2 (en) * | 1996-11-20 | 2001-08-02 | Yale University | Survivin, a protein that inhibits cellular apoptosis, and its modulation |
WO1999050637A2 (en) * | 1998-03-27 | 1999-10-07 | Ludwig Institute For Cancer Research | Isolated multimeric complexes useful in analysis of t cells, peptides useful in making the complexes, and uses thereof |
AU768834B2 (en) * | 1998-04-01 | 2004-01-08 | Yale University | A method for selectively modulating the interactions between survivin and tubulin |
AU4990999A (en) | 1998-07-14 | 2000-02-07 | Jenner Biotherapies, Inc. | Survivin, and peptides thereof, as an anti-cancer vaccine |
ES2747357T3 (es) * | 2001-03-14 | 2020-03-10 | Dako Denmark As | Construcciones de moléculas MHC y sus usos para el diagnóstico y terapia |
US7892559B2 (en) | 2002-01-30 | 2011-02-22 | Survac Aps | Survivin-derived peptides and use thereof |
US20040210035A1 (en) * | 2002-01-30 | 2004-10-21 | Straten Eivind Per Thor | Survivin-derived peptides and use thereof |
DE10225144A1 (de) | 2002-05-29 | 2003-12-18 | Immatics Biotechnologies Gmbh | An MHC-Moleküle bindende Tumor-assoziierte Peptide |
KR101284237B1 (ko) | 2003-11-19 | 2013-07-09 | 수르벡 에이피에스 | Bcl-2 패밀리에 속한 단백질들, 그들의 단편들 및 암 환자에 대한 그들의 용도 |
-
2003
- 2003-11-19 US US10/715,417 patent/US7892559B2/en active Active
-
2004
- 2004-01-30 EP EP14191676.7A patent/EP2857034B1/en not_active Expired - Lifetime
- 2004-01-30 JP JP2005518634A patent/JP5121143B2/ja not_active Expired - Lifetime
- 2004-01-30 US US10/543,755 patent/US8318174B2/en active Active
- 2004-01-30 AT AT08163405T patent/ATE454159T1/de active
- 2004-01-30 PT PT09155102T patent/PT2092938E/pt unknown
- 2004-01-30 CN CN2004800070526A patent/CN1767848B/zh not_active Expired - Lifetime
- 2004-01-30 MX MXPA05008128A patent/MXPA05008128A/es active IP Right Grant
- 2004-01-30 ES ES08163405T patent/ES2339193T3/es not_active Expired - Lifetime
- 2004-01-30 CA CA2513104A patent/CA2513104C/en not_active Expired - Lifetime
- 2004-01-30 DE DE602004032483T patent/DE602004032483D1/de not_active Expired - Lifetime
- 2004-01-30 EP EP10180878.0A patent/EP2359841B1/en not_active Expired - Lifetime
- 2004-01-30 EP EP09155102A patent/EP2092938B1/en not_active Expired - Lifetime
- 2004-01-30 ES ES04706615T patent/ES2312956T3/es not_active Expired - Lifetime
- 2004-01-30 EP EP08163405A patent/EP2005966B1/en not_active Expired - Lifetime
- 2004-01-30 WO PCT/DK2004/000062 patent/WO2004067023A2/en active IP Right Grant
- 2004-01-30 AT AT09155102T patent/ATE506962T1/de active
- 2004-01-30 PT PT04706615T patent/PT1587532E/pt unknown
- 2004-01-30 NZ NZ541510A patent/NZ541510A/en unknown
- 2004-01-30 PT PT08163405T patent/PT2005966E/pt unknown
- 2004-01-30 EP EP04706615A patent/EP1587532B1/en not_active Expired - Lifetime
- 2004-01-30 DE DE602004016287T patent/DE602004016287D1/de not_active Expired - Lifetime
- 2004-01-30 CN CN2010101195668A patent/CN101906148B/zh not_active Expired - Lifetime
- 2004-01-30 DE DE602004025059T patent/DE602004025059D1/de not_active Expired - Lifetime
- 2004-01-30 AU AU2004208469A patent/AU2004208469B2/en not_active Expired
- 2004-01-30 EA EA200501206A patent/EA008026B1/ru not_active IP Right Cessation
- 2004-01-30 AT AT04706615T patent/ATE406906T1/de active
-
2005
- 2005-08-29 NO NO20053999A patent/NO333213B1/no not_active IP Right Cessation
-
2006
- 2006-07-10 HK HK06107692.0A patent/HK1087335A1/xx not_active IP Right Cessation
-
2009
- 2009-06-22 HK HK09105575.3A patent/HK1126668A1/xx not_active IP Right Cessation
-
2012
- 2012-09-28 US US13/630,862 patent/US9534030B2/en not_active Ceased
-
2018
- 2018-07-19 US US16/039,999 patent/USRE48522E1/en active Active
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200501206A1 (ru) | Производные от сурвивина пептиды и их применение | |
CY1117387T1 (el) | ΜΟΝΟΚΛΩΝΙΚΑ ΑΝΤΙΣΩΜΑΤΑ Ν-11 ΔΙΑΣΠΑΣΜΕΝΟΥ β-ΑΜΥΛΟΕΙΔΟΥΣ, ΣΥΝΘΕΣΕΙΣ, ΜΕΘΟΔΟΙ ΚΑΙ ΧΡΗΣΕΙΣ | |
IL176007A0 (en) | Antibodies specific to c35 and pharmaceutical compositions containing the same | |
EA200801509A1 (ru) | Человеческие моноклональные антитела к протеинтирозинкиназе 7 ( ptk7) и способы применения антител против ptk7 | |
AR006250A1 (es) | Compuestos y metodos para la inmunoterapia e inmunodiagnostico del cancer prostatico | |
TR200103560T2 (tr) | Göğüs kanserinin teşhis ve tedavisi için bileşimler ve bunların kullanımı | |
ATE451388T1 (de) | Tumorassoziierte peptide, die promiskuitiv an humane leukozytenantigen- (hla-) moleküle der klasse ii binden | |
CY1112055T1 (el) | Συνθεσεις και μεθοδοι για την διαγνωση και θεραπευτικη αγωγη ογκου πνευμονα | |
DE602005015990D1 (de) | Immunogene t-helfer epitope von menschlichen tumorantigenen und deren verwendung in immunotherapeutischen methoden | |
ATE512160T1 (de) | T-cell-epitope aus dem unreifen lamininrezeptorprotein (oncofoetal antigen) und deren medizinische verwendungen | |
PE20050712A1 (es) | Anticuerpos rg1 | |
PH12015501467A1 (en) | Anti-lamp1 antibodies and antibody drug conjugates, and uses thereof | |
DE69931482D1 (de) | Isolierte peptide die aminosäuresequenzen von ny-eso-1 entsprechen und an mhc-klasse i und mhc klasse ii moleküle binden, und deren verwendungen | |
WO2002053700A3 (en) | Isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof | |
HUP0302566A2 (hu) | Készítmények és eljárások emlőrák gyógykezelésére és diagnosztizálására | |
ATE509025T1 (de) | ßMIT MHC-KLASSE-I-PEPTIDEPITOPEN KOVALENT VERKN PFTES MEMBRANVERANKERTES BETA2-MIKROGLOBULINß | |
NO20181511A1 (no) | Survivin-avledede peptider og bruken av dem | |
DE69828791D1 (de) | Das antigen ha-1 | |
UY26170A1 (es) | Antigeno (c42) asociados a tumores | |
AR023794A1 (es) | Antigeno asociado con tumores | |
UY26127A1 (es) | Antígeno asociado con tumores | |
CY1114151T1 (el) | Ανθρωπινα μονοκλωνικα αντισωματα ως προς την κιναση τυροσινης πρωτεϊνης 7 (ρτκ7) και η χρηση αυτων | |
CY1113958T1 (el) | Ανθρωπινα μονοκλωνικα αντισωματα σε φουκοζυλ-gμ1 και μεθοδοι για τη χρηση αντι-φουκοζυλ-gμ1 | |
CY1115252T1 (el) | Αντισωμα εναντιον cd22 για την θεραπευτικη αγωγη ογκου αιματοποιητικης προελευσης | |
AR019387A1 (es) | Polipeptido aislado, polinucleotido aislado, vector de expresion, celula huesped, composicion farmaceutica, vacuna, anticuerpo aislado, kit de diagnostico,oligonucleotido, metodo para inhibir el desarrollo de cancer, proteinas de fusion, metodo para separar celulas tumorales de una muestra biologica |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |