EA200500870A1 - Пептиды, которые нацелены на опухоль и эндотелиальные клетки, композиции и их применения - Google Patents
Пептиды, которые нацелены на опухоль и эндотелиальные клетки, композиции и их примененияInfo
- Publication number
- EA200500870A1 EA200500870A1 EA200500870A EA200500870A EA200500870A1 EA 200500870 A1 EA200500870 A1 EA 200500870A1 EA 200500870 A EA200500870 A EA 200500870A EA 200500870 A EA200500870 A EA 200500870A EA 200500870 A1 EA200500870 A1 EA 200500870A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- peptides
- compositions
- endothelial cells
- targeted
- applications
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 210000002889 endothelial cell Anatomy 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 206010027476 Metastases Diseases 0.000 abstract 1
- 230000033115 angiogenesis Effects 0.000 abstract 1
- 230000001772 anti-angiogenic effect Effects 0.000 abstract 1
- 230000002001 anti-metastasis Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 239000000969 carrier Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000012010 growth Effects 0.000 abstract 1
- 230000009401 metastasis Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000002600 positron emission tomography Methods 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
- 108700012359 toxins Proteins 0.000 abstract 1
- 210000004881 tumor cell Anatomy 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42917402P | 2002-11-25 | 2002-11-25 | |
| US47553903P | 2003-06-02 | 2003-06-02 | |
| PCT/US2003/037895 WO2004063213A2 (en) | 2002-11-25 | 2003-11-25 | Peptides which target tumor and endothelial cells, compositions and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| EA200500870A1 true EA200500870A1 (ru) | 2006-04-28 |
Family
ID=32397181
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200500870A EA200500870A1 (ru) | 2002-11-25 | 2003-11-25 | Пептиды, которые нацелены на опухоль и эндотелиальные клетки, композиции и их применения |
| EA200500871A EA200500871A1 (ru) | 2002-11-25 | 2003-11-25 | Пептиды, ингибирующие ангиогенез, миграцию клеток, инвазию клеток и пролиферацию клеток, композиции и их применение |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200500871A EA200500871A1 (ru) | 2002-11-25 | 2003-11-25 | Пептиды, ингибирующие ангиогенез, миграцию клеток, инвазию клеток и пролиферацию клеток, композиции и их применение |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US20050020810A1 (https=) |
| EP (2) | EP1569678A4 (https=) |
| JP (2) | JP2006515866A (https=) |
| KR (2) | KR20050096917A (https=) |
| AU (2) | AU2003297609A1 (https=) |
| BR (2) | BR0316523A (https=) |
| CA (2) | CA2507045A1 (https=) |
| EA (2) | EA200500870A1 (https=) |
| HR (2) | HRP20050585A2 (https=) |
| MX (2) | MXPA05005545A (https=) |
| NO (2) | NO20053112L (https=) |
| NZ (2) | NZ540363A (https=) |
| PL (2) | PL377701A1 (https=) |
| WO (2) | WO2004047771A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA05005545A (es) * | 2002-11-25 | 2005-10-18 | Attenuon Llc | Peptidos que se dirigen a celulas tomurales y endoteliales, composiciones y usos de los mismos. |
| EP1766405A1 (en) * | 2004-05-21 | 2007-03-28 | MDS Inc. doing Business Through Its MDS Pharma Services Division | Method of quantifying the cell-binding properties of a medical device |
| US20060078535A1 (en) * | 2004-10-13 | 2006-04-13 | The Regents Of The University Of Michigan | Anticancer compounds and methods |
| KR20070100832A (ko) * | 2005-02-01 | 2007-10-11 | 아테뉴온, 엘엘씨 | 항혈관신생 ｐｈｓｃｎ 펩티드를 함유하는 조성물 |
| WO2006084016A1 (en) | 2005-02-01 | 2006-08-10 | Attenuon, Llc | ACID ADDITION SALTS OF Ac-PHSCN-NH2 |
| AU2006350707A1 (en) * | 2006-11-08 | 2008-05-15 | Chongxi Yu | Transdermal delivery systems of peptides and related compounds |
| AU2016213759B2 (en) * | 2006-11-08 | 2018-03-29 | Chongxi Yu | Transdermal delivery systems of peptides and related compounds |
| PL2427475T3 (pl) | 2009-05-08 | 2021-07-19 | Techfields Biochem Co., Ltd. | Kompozycje proleku o wysokim przenikaniu peptydów i związków powiązanych z peptydami |
| KR101228668B1 (ko) | 2010-09-17 | 2013-01-31 | 가톨릭대학교 산학협력단 | 혈관신생 억제 활성을 갖는 펩타이드 및 이의 용도 |
| CA2839702C (en) | 2011-06-23 | 2021-04-20 | Board Of Regents, The University Of Texas System | Identifying peptides at the single molecule level |
| US11435358B2 (en) | 2011-06-23 | 2022-09-06 | Board Of Regents, The University Of Texas System | Single molecule peptide sequencing |
| CN102417540A (zh) * | 2011-11-21 | 2012-04-18 | 中国药科大学 | 一种聚乙二醇修饰的整合素阻断剂hm-3及其应用 |
| JP6206987B2 (ja) * | 2012-05-11 | 2017-10-04 | メディカス バイオサイエンシーズ，エルエルシー | 網膜剥離の処置のための生体適合性ヒドロゲル製剤 |
| AU2012381990B2 (en) | 2012-06-04 | 2017-02-23 | Nutrien Ag Solutions (Canada) Inc. | Formulations containing paraffinic oil and anti-settling agent |
| ES2664411T3 (es) | 2013-03-15 | 2018-04-19 | Suncor Energy Inc. | Composiciones herbicidas |
| JP5970439B2 (ja) * | 2013-09-20 | 2016-08-17 | チョンシー ユー | ペプチド及び関連化合物の経皮送達システム |
| CA3208970A1 (en) | 2014-09-15 | 2016-05-06 | Board Of Regents, The University Of Texas System | Improved single molecule peptide sequencing |
| CA3110800A1 (en) | 2018-07-12 | 2020-01-16 | Board Of Regents, The University Of Texas System | Molecular neighborhood detection by oligonucleotides |
| CA3117476A1 (en) | 2018-10-05 | 2020-04-09 | Board Of Regents, The University Of Texas System | Solid-phase n-terminal peptide capture and release |
| WO2020150831A1 (en) | 2019-01-25 | 2020-07-30 | Suncor Energy Inc. | Photosensitizer compounds, methods of manufacture and application to plants |
| CN113677204B (zh) | 2019-02-15 | 2024-03-05 | 桑科能源股份有限公司 | 原卟啉ix衍生物改善植物健康的用途 |
Family Cites Families (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) * | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4440788A (en) * | 1980-05-13 | 1984-04-03 | Mitsubishi Chemical Industries, Limited | Cysteine derivatives |
| WO1981003330A1 (fr) | 1980-05-13 | 1981-11-26 | Mitsubishi Chem Ind | Derives de la cysteine et leur production |
| US4394519A (en) * | 1982-01-19 | 1983-07-19 | Research Corporation | Amino acid blocking agents |
| GB8504253D0 (en) * | 1985-02-19 | 1985-03-20 | Ici Plc | Electrostatic spraying apparatus |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| DE3815221C2 (de) | 1988-05-04 | 1995-06-29 | Gradinger F Hermes Pharma | Verwendung einer Retinol- und/oder Retinsäureester enthaltenden pharmazeutischen Zubereitung zur Inhalation zur Einwirkung auf die Schleimhäute des Tracheo-Bronchialtraktes einschließlich der Lungenalveolen |
| US5091176A (en) * | 1988-11-02 | 1992-02-25 | W. R. Grace & Co.-Conn. | Polymer-modified peptide drugs having enhanced biological and pharmacological activities |
| US5443816A (en) * | 1990-08-08 | 1995-08-22 | Rhomed Incorporated | Peptide-metal ion pharmaceutical preparation and method |
| US5229366A (en) * | 1990-10-23 | 1993-07-20 | Fuji Photo Film Co., Ltd. | Peptide-containing polyethylene glycol derivatives and application thereof |
| US5149801A (en) * | 1990-11-21 | 1992-09-22 | The Regents Of The University Of California | Boronated porphyrin compounds |
| US5561220A (en) * | 1991-02-08 | 1996-10-01 | Diatech, Inc. | Technetium-99m labeled peptides for imaging inflammation |
| US5698155A (en) * | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| US5556609A (en) | 1992-02-20 | 1996-09-17 | Rhomed Incorporated | YIGSR peptide radiopharmaceutical applications |
| US5608110A (en) | 1993-06-15 | 1997-03-04 | Bracco International B.V. | Heteroatom-bearing ligands and metal complexes thereof |
| US5639725A (en) * | 1994-04-26 | 1997-06-17 | Children's Hospital Medical Center Corp. | Angiostatin protein |
| EP0814860B1 (en) | 1995-03-14 | 1999-11-03 | Siemens Aktiengesellschaft | Ultrasonic atomizer device with removable precision dosating unit |
| US5970974A (en) * | 1995-03-14 | 1999-10-26 | Siemens Aktiengesellschaft | Dosating unit for an ultrasonic atomizer device |
| US5618513A (en) | 1995-06-07 | 1997-04-08 | Mallinckrodt Medical, Inc. | Method for preparing radiolabeled peptides |
| MY147327A (en) * | 1995-06-29 | 2012-11-30 | Novartis Ag | Somatostatin peptides |
| CA2265484C (en) * | 1996-09-10 | 2008-12-02 | The Burnham Institute | Tumor homing molecules, conjugates derived therefrom, and methods of using same |
| US6025150A (en) * | 1996-11-21 | 2000-02-15 | The Regents Of The University Of Michigan | Methods and compositions for wound healing |
| US6331409B1 (en) * | 1996-11-21 | 2001-12-18 | The Regents Of The University Of Michigan | Methods and compositions for wound healing |
| US6001965A (en) * | 1996-11-21 | 1999-12-14 | The Regents Of The University Of Michigan | Anticancer compounds and methods |
| US6011170A (en) * | 1997-01-14 | 2000-01-04 | Kaneka Corporation | Process for producing of cysteine derivatives |
| US5994309A (en) * | 1997-07-25 | 1999-11-30 | Angstrom Pharmaceuticals, Inc. | Anti-invasive and anti-angiogenic compositions and methods |
| JP2001516055A (ja) * | 1997-09-10 | 2001-09-25 | ザ バーナム インスティチュート | 腫瘍中の血管形成血管系にホーミングする分子を同定する方法 |
| US5954047A (en) * | 1997-10-17 | 1999-09-21 | Systemic Pulmonary Development, Ltd. | Methods and apparatus for delivering aerosolized medication |
| JP2002525265A (ja) | 1998-08-14 | 2002-08-13 | アドミニストレイターズ オブ ザ トゥレーン エジュケーショナル ファウンド | 成長ホルモン放出活性を有する化合物 |
| ATE366936T1 (de) | 2001-01-18 | 2007-08-15 | Univ Michigan | Zusammensetzungen und verfahren zur verwendung von fibronektin-fragmenten bei krebsdiagnose |
| MXPA05005545A (es) * | 2002-11-25 | 2005-10-18 | Attenuon Llc | Peptidos que se dirigen a celulas tomurales y endoteliales, composiciones y usos de los mismos. |
-
2003
- 2003-11-25 MX MXPA05005545A patent/MXPA05005545A/es unknown
- 2003-11-25 AU AU2003297609A patent/AU2003297609A1/en not_active Abandoned
- 2003-11-25 EA EA200500870A patent/EA200500870A1/ru unknown
- 2003-11-25 PL PL377701A patent/PL377701A1/pl not_active Application Discontinuation
- 2003-11-25 JP JP2005512876A patent/JP2006515866A/ja active Pending
- 2003-11-25 CA CA002507045A patent/CA2507045A1/en not_active Abandoned
- 2003-11-25 JP JP2005510345A patent/JP2006514116A/ja active Pending
- 2003-11-25 BR BR0316523-0A patent/BR0316523A/pt not_active IP Right Cessation
- 2003-11-25 CA CA002506813A patent/CA2506813A1/en not_active Abandoned
- 2003-11-25 WO PCT/US2003/038175 patent/WO2004047771A2/en not_active Ceased
- 2003-11-25 PL PL377763A patent/PL377763A1/pl not_active Application Discontinuation
- 2003-11-25 EP EP03796483A patent/EP1569678A4/en not_active Withdrawn
- 2003-11-25 AU AU2003298726A patent/AU2003298726A1/en not_active Abandoned
- 2003-11-25 US US10/722,843 patent/US20050020810A1/en not_active Abandoned
- 2003-11-25 BR BR0316550-7A patent/BR0316550A/pt not_active IP Right Cessation
- 2003-11-25 HR HR20050585A patent/HRP20050585A2/xx not_active Application Discontinuation
- 2003-11-25 KR KR1020057009356A patent/KR20050096917A/ko not_active Withdrawn
- 2003-11-25 HR HR20050584A patent/HRP20050584A2/hr not_active Application Discontinuation
- 2003-11-25 EP EP03812058A patent/EP1594521A4/en not_active Withdrawn
- 2003-11-25 EA EA200500871A patent/EA200500871A1/ru unknown
- 2003-11-25 US US10/723,144 patent/US7517855B2/en not_active Expired - Fee Related
- 2003-11-25 NZ NZ540363A patent/NZ540363A/en unknown
- 2003-11-25 NZ NZ540889A patent/NZ540889A/en not_active IP Right Cessation
- 2003-11-25 WO PCT/US2003/037895 patent/WO2004063213A2/en not_active Ceased
- 2003-11-25 KR KR1020057009447A patent/KR20050097494A/ko not_active Withdrawn
- 2003-11-25 MX MXPA05005469A patent/MXPA05005469A/es not_active Application Discontinuation
-
2005
- 2005-06-24 NO NO20053112A patent/NO20053112L/no not_active Application Discontinuation
- 2005-06-24 NO NO20053111A patent/NO20053111L/no not_active Application Discontinuation
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