EA200101110A1 - Новые фармацевтические комбинации ингибиторов nos - Google Patents

Новые фармацевтические комбинации ингибиторов nos

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Publication number
EA200101110A1
EA200101110A1 EA200101110A EA200101110A EA200101110A1 EA 200101110 A1 EA200101110 A1 EA 200101110A1 EA 200101110 A EA200101110 A EA 200101110A EA 200101110 A EA200101110 A EA 200101110A EA 200101110 A1 EA200101110 A1 EA 200101110A1
Authority
EA
Eurasian Patent Office
Prior art keywords
sleep
inhibitors
nos
disruption
disorders
Prior art date
Application number
EA200101110A
Other languages
English (en)
Russian (ru)
Inventor
Марио Дэвид Салтарелли
Джон Адамс Лоуэ III
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA200101110A1 publication Critical patent/EA200101110A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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DE10001785A1 (de) * 2000-01-18 2001-07-19 Boehringer Ingelheim Pharma NK¶1¶-Rezeptor-Antagonisten zur Behandlung des Restless Legs Syndroms
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US6803470B2 (en) * 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
DOP2002000467A (es) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas
CN100368409C (zh) * 2003-06-24 2008-02-13 神经研究公司 8-氮杂双环[3.2.1]辛烷衍生物及其用于制备单胺神经递质再摄取抑制剂的用途
EP1634598A1 (en) * 2004-09-07 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion
EP2152271B1 (en) 2007-06-08 2015-10-21 Janssen Pharmaceutica, N.V. Piperidine/piperazine derivatives
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine / piperazine derivatives
WO2008148851A1 (en) 2007-06-08 2008-12-11 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
CN101678019B (zh) 2007-06-08 2016-03-30 詹森药业有限公司 哌啶/哌嗪衍生物
WO2009147170A2 (en) 2008-06-05 2009-12-10 Janssen Pharmaceutica Nv Drug combinations comprising a dgat inhibitor and a ppar-agonist
WO2010101246A1 (ja) 2009-03-05 2010-09-10 塩野義製薬株式会社 Ｎｐｙ ｙ５受容体拮抗作用を有するピペリジンおよびピロリジン誘導体
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
EP3983392A4 (en) * 2019-06-14 2023-12-06 SRX Cardio, LLC COMPOUNDS FOR MODULATING PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 (PCSK9)

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EP1178784A1 (en) 2002-02-13
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IS6126A (is) 2001-10-26
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NO20015651D0 (no) 2001-11-20
AU2935300A (en) 2000-12-12
HN2000000045A (es) 2001-03-02
HUP0301287A2 (hu) 2003-08-28
WO2000071107A2 (en) 2000-11-30
IL145955A0 (en) 2002-07-25
KR20020010916A (ko) 2002-02-06
MA26732A1 (fr) 2004-12-20
NO20015651L (no) 2002-01-18
EE200100611A (et) 2003-02-17
PE20010157A1 (es) 2001-02-16
TR200103351T2 (tr) 2002-06-21
GT200000071A (es) 2001-11-08
CN1617743A (zh) 2005-05-18
PL358538A1 (en) 2004-08-09
HRP20010862A2 (en) 2003-06-30
MXPA01011978A (es) 2002-05-06
WO2000071107A8 (en) 2002-01-24
OA11943A (en) 2006-04-12
PA8494601A1 (es) 2002-08-29
UY26148A1 (es) 2000-12-29
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