IL145955A0 - New pharmaceutical combinations for nos inhibitors - Google Patents
New pharmaceutical combinations for nos inhibitorsInfo
- Publication number
- IL145955A0 IL145955A0 IL14595500A IL14595500A IL145955A0 IL 145955 A0 IL145955 A0 IL 145955A0 IL 14595500 A IL14595500 A IL 14595500A IL 14595500 A IL14595500 A IL 14595500A IL 145955 A0 IL145955 A0 IL 145955A0
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical combinations
- new pharmaceutical
- nos inhibitors
- inhibitors
- nos
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
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- A61K31/13—Amines
- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/443—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4433—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with oxygen as a ring hetero atom
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
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- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
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- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
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- A61K31/4965—Non-condensed pyrazines
- A61K31/497—Non-condensed pyrazines containing further heterocyclic rings
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- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US13552099P | 1999-05-21 | 1999-05-21 | |
PCT/IB2000/000295 WO2000071107A2 (en) | 1999-05-21 | 2000-03-16 | New pharmaceutical combinations for nos inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
IL145955A0 true IL145955A0 (en) | 2002-07-25 |
Family
ID=22468464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL14595500A IL145955A0 (en) | 1999-05-21 | 2000-03-16 | New pharmaceutical combinations for nos inhibitors |
Country Status (33)
Country | Link |
---|---|
EP (1) | EP1178784A1 (en) |
JP (1) | JP2003523941A (en) |
KR (1) | KR20020010916A (en) |
CN (1) | CN1617743A (en) |
AP (1) | AP2001002326A0 (en) |
AR (1) | AR022640A1 (en) |
AU (1) | AU2935300A (en) |
BG (1) | BG106208A (en) |
BR (1) | BR0010820A (en) |
CA (1) | CA2374668A1 (en) |
CO (1) | CO5160295A1 (en) |
DZ (1) | DZ3041A1 (en) |
EA (1) | EA200101110A1 (en) |
EE (1) | EE200100611A (en) |
GT (1) | GT200000071A (en) |
HN (1) | HN2000000045A (en) |
HR (1) | HRP20010862A2 (en) |
HU (1) | HUP0301287A3 (en) |
IL (1) | IL145955A0 (en) |
IS (1) | IS6126A (en) |
MA (1) | MA26732A1 (en) |
MX (1) | MXPA01011978A (en) |
NO (1) | NO20015651L (en) |
OA (1) | OA11943A (en) |
PA (1) | PA8494601A1 (en) |
PE (1) | PE20010157A1 (en) |
PL (1) | PL358538A1 (en) |
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TN (1) | TNSN00106A1 (en) |
TR (1) | TR200103351T2 (en) |
UY (1) | UY26148A1 (en) |
WO (1) | WO2000071107A2 (en) |
ZA (1) | ZA200109555B (en) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10001785A1 (en) * | 2000-01-18 | 2001-07-19 | Boehringer Ingelheim Pharma | Use of NK-1 receptor antagonists for treatment of restless legs syndrome |
GB0019006D0 (en) * | 2000-08-04 | 2000-09-20 | Astrazeneca Ab | Novel compounds |
US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
DOP2002000467A (en) * | 2001-10-10 | 2003-04-15 | Pfizer Prod Inc | 2-AMINO-6 (PHENYL REPLACED IN POSITIONS 2,4,5) -PIRIDINES |
US6803470B2 (en) * | 2001-10-10 | 2004-10-12 | Pfizer Inc | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines |
UA82517C2 (en) * | 2003-06-24 | 2008-04-25 | Ньюросерч А/С | Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
EP1634598A1 (en) * | 2004-09-07 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion |
JP5464709B2 (en) | 2007-06-08 | 2014-04-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Piperidine / piperazine derivatives |
JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine/Piperazine derivatives |
US8835437B2 (en) | 2007-06-08 | 2014-09-16 | Janssen Pharmaceutica N.V. | Piperidine/piperazine derivatives |
CN101678019B (en) | 2007-06-08 | 2016-03-30 | 詹森药业有限公司 | Piperidine/piperazine derivatives |
EP2296659B1 (en) | 2008-06-05 | 2016-12-21 | Janssen Pharmaceutica, N.V. | Drug combinations comprising a DGAT inhibitor and a PPAR-agonist |
WO2010101246A1 (en) * | 2009-03-05 | 2010-09-10 | 塩野義製薬株式会社 | Piperidine and pyrrolidine derivatives having npy y5 receptor antagonism |
US10154988B2 (en) | 2012-11-14 | 2018-12-18 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
CN114206843A (en) * | 2019-06-14 | 2022-03-18 | Srx心脏有限责任公司 | Compounds for modulating proprotein convertase subtilisin/Kexin type 9(PCSK9) |
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2000
- 2000-03-16 HU HU0301287A patent/HUP0301287A3/en unknown
- 2000-03-16 SK SK1660-2001A patent/SK16602001A3/en unknown
- 2000-03-16 MX MXPA01011978A patent/MXPA01011978A/en unknown
- 2000-03-16 EE EEP200100611A patent/EE200100611A/en unknown
- 2000-03-16 EA EA200101110A patent/EA200101110A1/en unknown
- 2000-03-16 WO PCT/IB2000/000295 patent/WO2000071107A2/en not_active Application Discontinuation
- 2000-03-16 OA OA1200100301A patent/OA11943A/en unknown
- 2000-03-16 IL IL14595500A patent/IL145955A0/en unknown
- 2000-03-16 CN CNA008078785A patent/CN1617743A/en active Pending
- 2000-03-16 AP APAP/P/2001/002326A patent/AP2001002326A0/en unknown
- 2000-03-16 EP EP00907891A patent/EP1178784A1/en not_active Ceased
- 2000-03-16 BR BR0010820-0A patent/BR0010820A/en not_active IP Right Cessation
- 2000-03-16 TR TR2001/03351T patent/TR200103351T2/en unknown
- 2000-03-16 PL PL00358538A patent/PL358538A1/en not_active Application Discontinuation
- 2000-03-16 KR KR1020017014884A patent/KR20020010916A/en not_active Application Discontinuation
- 2000-03-16 AU AU29353/00A patent/AU2935300A/en not_active Abandoned
- 2000-03-16 JP JP2000619414A patent/JP2003523941A/en not_active Withdrawn
- 2000-03-16 CA CA002374668A patent/CA2374668A1/en not_active Abandoned
- 2000-04-04 HN HN2000000045A patent/HN2000000045A/en unknown
- 2000-04-04 CO CO00024427A patent/CO5160295A1/en unknown
- 2000-04-25 PA PA20008494601A patent/PA8494601A1/en unknown
- 2000-05-17 GT GT200000071A patent/GT200000071A/en unknown
- 2000-05-17 DZ DZ000084A patent/DZ3041A1/en active
- 2000-05-17 TN TNTNSN00106A patent/TNSN00106A1/en unknown
- 2000-05-17 MA MA25976A patent/MA26732A1/en unknown
- 2000-05-18 UY UY26148A patent/UY26148A1/en not_active Application Discontinuation
- 2000-05-19 AR ARP000102387A patent/AR022640A1/en not_active Application Discontinuation
- 2000-05-19 PE PE2000000473A patent/PE20010157A1/en not_active Application Discontinuation
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2001
- 2001-10-26 IS IS6126A patent/IS6126A/en unknown
- 2001-11-20 ZA ZA200109555A patent/ZA200109555B/en unknown
- 2001-11-20 NO NO20015651A patent/NO20015651L/en not_active Application Discontinuation
- 2001-11-20 HR HR20010862A patent/HRP20010862A2/en not_active Application Discontinuation
- 2001-12-11 BG BG06208A patent/BG106208A/en unknown
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