GT200000071A - NEW PHARMACEUTICAL COMBINATIONS FOR INHIBITORS OF THE US. - Google Patents

NEW PHARMACEUTICAL COMBINATIONS FOR INHIBITORS OF THE US.

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Publication number
GT200000071A
GT200000071A GT200000071A GT200000071A GT200000071A GT 200000071 A GT200000071 A GT 200000071A GT 200000071 A GT200000071 A GT 200000071A GT 200000071 A GT200000071 A GT 200000071A GT 200000071 A GT200000071 A GT 200000071A
Authority
GT
Guatemala
Prior art keywords
disorders
inhibitors
new pharmaceutical
disorder
affections
Prior art date
Application number
GT200000071A
Other languages
Spanish (es)
Inventor
Mario David Saltarelli
John Adams Lowe Iii
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of GT200000071A publication Critical patent/GT200000071A/en

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
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    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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  • Hospice & Palliative Care (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A NUEVOS USOS FARMACEUTICOS PARA COMPUESTOS QUE PRESENTAN ACTIVIDAD COMO INHIBIDORES DE LA OXIDO SINTETASA ("NOS"), SOLOS O EN COMBINACION CON OTRO AGENTE ACTIVO, EN PARTICULAR, UN SSRI O UN ANTAGONISTA DEL RECEPTOR NK1, PARA EL TRATAMIENTO DE TRASTORNOS O AFECCIONES CUYO TRATAMIENTO PUEDE REALIZARSE O FACILITARSE MEDIANTE LA ALTERACION DE LOS RITMOS CIRCADIANOS. SON EJEMPLOS DE TALES TRASTORNOS Y AFECCIONES: LA CEGUERA, LA OBESIDAD, EL TRASTORNO AFECTIVO ESTACIONAL, EL TRASTORNO BIPOLAR, EL DESFASE HORARIO, TRASTORNO DE LOS CICLOS CIRCADIANOS DEL SUEÑO, NARCOLEPSIA Y TRASTORNOS DEL SUEÑO ASOCIADOS CON EL TRABAJO A TURNOS O CON HORARIOS DE TRABAJO IRREGULARES; ENEURESIS NOCTURNA Y SINDROME DE LAS PIERNAS INQUIETAS.THE PRESENT INVENTION REFERS TO NEW PHARMACEUTICAL USES FOR COMPOUNDS THAT PRESENT ACTIVITY AS INHIBITORS OF SYNTHEASE OXIDE ("US"), ONLY OR IN COMBINATION WITH ANOTHER ACTIVE AGENT, IN PARTICULAR, AN SSRI OR ANTAGONIST OF THE RECEIVER NK1, OF DISORDERS OR AFFECTIONS WHEN TREATMENT CAN BE CARRIED OUT OR FACILITATED BY THE ALTERATION OF CIRCADIAN RHYTHMS. THEY ARE EXAMPLES OF SUCH DISORDERS AND AFFECTIONS: THE BLINDNESS, OBESITY, THE SEASONAL AFFECTIVE DISORDER, THE BIPOLAR DISORDER, THE SCHEDULE SCROLL, DISORDER OF THE CIRCADIAN CYCLES OF THE DREAM, NARCOLEPSY AND DISORDERS TO THE DREAMS TO THE DREAMS IRREGULAR WORK; NIGHT ENEURESIS AND SYNDROME OF THE INQUIET LEGS.

GT200000071A 1999-05-21 2000-05-17 NEW PHARMACEUTICAL COMBINATIONS FOR INHIBITORS OF THE US. GT200000071A (en)

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DE10001785A1 (en) * 2000-01-18 2001-07-19 Boehringer Ingelheim Pharma Use of NK-1 receptor antagonists for treatment of restless legs syndrome
GB0019006D0 (en) * 2000-08-04 2000-09-20 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
US6803470B2 (en) * 2001-10-10 2004-10-12 Pfizer Inc 2-amino-6-(2,4,5-substituted-phenyl)-pyridines
DOP2002000467A (en) * 2001-10-10 2003-04-15 Pfizer Prod Inc 2-AMINO-6 (PHENYL REPLACED IN POSITIONS 2,4,5) -PIRIDINES
BRPI0411608A (en) 2003-06-24 2006-08-08 Neurosearch As 8-aza-bicyclo [3.2.1] octane derivative, pharmaceutical composition, use of the compound, and method of treating, preventing or alleviating a disease, disorder or condition of a living animal organism
EP1634598A1 (en) * 2004-09-07 2006-03-15 Laboratorios Del Dr. Esteve, S.A. Use of piperazine derivatives and analogues for the manufacture of a medicament for the prophylaxis and/or treatment of disorders of food ingestion
CA2687918C (en) 2007-06-08 2016-11-08 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
JO2972B1 (en) 2007-06-08 2016-03-15 جانسين فارماسوتيكا ان. في Piperidine/Piperazine derivatives
AU2008258549B2 (en) 2007-06-08 2013-11-14 Janssen Pharmaceutica N.V. Piperidine/piperazine derivatives
BRPI0813331A2 (en) 2007-06-08 2014-12-23 Janssen Pharmaceutica Nv PIPERIDINE / PIPERAZINE Derivatives
WO2009147170A2 (en) 2008-06-05 2009-12-10 Janssen Pharmaceutica Nv Drug combinations comprising a dgat inhibitor and a ppar-agonist
EP2404902A1 (en) 2009-03-05 2012-01-11 Shionogi&Co., Ltd. Piperidine and pyrrolidine derivatives having npy y5 receptor antagonism
US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
WO2020252383A2 (en) * 2019-06-14 2020-12-17 Srx Cardio, Llc Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (pcsk9)

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IS6126A (en) 2001-10-26
AP2001002326A0 (en) 2001-12-31
AU2935300A (en) 2000-12-12
PE20010157A1 (en) 2001-02-16
HUP0301287A2 (en) 2003-08-28
MXPA01011978A (en) 2002-05-06
HUP0301287A3 (en) 2005-03-29
EE200100611A (en) 2003-02-17
WO2000071107A2 (en) 2000-11-30
HRP20010862A2 (en) 2003-06-30
NO20015651L (en) 2002-01-18
UY26148A1 (en) 2000-12-29
SK16602001A3 (en) 2003-03-04
DZ3041A1 (en) 2004-03-27
PL358538A1 (en) 2004-08-09
EP1178784A1 (en) 2002-02-13
PA8494601A1 (en) 2002-08-29
EA200101110A1 (en) 2002-08-29
CA2374668A1 (en) 2000-11-30
MA26732A1 (en) 2004-12-20
WO2000071107A8 (en) 2002-01-24
TR200103351T2 (en) 2002-06-21
NO20015651D0 (en) 2001-11-20
BG106208A (en) 2002-09-30
TNSN00106A1 (en) 2005-11-10
ZA200109555B (en) 2004-04-07
JP2003523941A (en) 2003-08-12
CO5160295A1 (en) 2002-05-30
KR20020010916A (en) 2002-02-06
AR022640A1 (en) 2002-09-04
HN2000000045A (en) 2001-03-02
IL145955A0 (en) 2002-07-25
CN1617743A (en) 2005-05-18
OA11943A (en) 2006-04-12

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