EA199900812A1 - Производные циклопентенона - Google Patents

Производные циклопентенона

Info

Publication number
EA199900812A1
EA199900812A1 EA199900812A EA199900812A EA199900812A1 EA 199900812 A1 EA199900812 A1 EA 199900812A1 EA 199900812 A EA199900812 A EA 199900812A EA 199900812 A EA199900812 A EA 199900812A EA 199900812 A1 EA199900812 A1 EA 199900812A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivative
cyclopentenone
rcoo
cyclopenten
agent
Prior art date
Application number
EA199900812A
Other languages
English (en)
Other versions
EA001808B1 (ru
Inventor
Нобуто Койама
Кацусиге Икаи
Ейдзи Кобайаси
Икуносин Като
Original Assignee
Такара Сузо Ко., Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Такара Сузо Ко., Лтд. filed Critical Такара Сузо Ко., Лтд.
Publication of EA199900812A1 publication Critical patent/EA199900812A1/ru
Publication of EA001808B1 publication Critical patent/EA001808B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/02—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen
    • C07C69/22—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety
    • C07C69/28—Esters of acyclic saturated monocarboxylic acids having the carboxyl group bound to an acyclic carbon atom or to hydrogen having three or more carbon atoms in the acid moiety esterified with dihydroxylic compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/013—Esters of alcohols having the esterified hydroxy group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Представлены производное циклопентенона, имеющее структуру 5-(RCOO-)-4-(RCOO-) - замещенного 2-циклопентен-1-она (Rи Rявляются одинаковыми или разными, и каждый из них является алкильной группой, алкенильной группой или арильной группой) или его оптически активное вещество; способ производства производного циклопентенона посредством реакции 4,5-дигидрокси-2-циклопентен-1-она с соответствующей карбоновой кислотой или ее реакционноспособным производным; и содержащее такое производное противораковое средство, средство, вызывающее апоптоз, и противомикробное средство.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA199900812A 1997-03-11 1998-02-26 Производные циклопентенона EA001808B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP7285597 1997-03-11
JP9001197 1997-03-26
PCT/JP1998/000817 WO1998040346A1 (fr) 1997-03-11 1998-02-26 Derives cyclopentenone

Publications (2)

Publication Number Publication Date
EA199900812A1 true EA199900812A1 (ru) 2000-04-24
EA001808B1 EA001808B1 (ru) 2001-08-27

Family

ID=26413994

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900812A EA001808B1 (ru) 1997-03-11 1998-02-26 Производные циклопентенона

Country Status (13)

Country Link
US (1) US6136854A (ru)
EP (1) EP0976717B1 (ru)
JP (1) JP3763585B2 (ru)
KR (1) KR100555843B1 (ru)
CN (1) CN1156432C (ru)
AT (1) ATE228110T1 (ru)
AU (1) AU730766B2 (ru)
CA (1) CA2283634A1 (ru)
DE (1) DE69809544T2 (ru)
EA (1) EA001808B1 (ru)
ES (1) ES2183328T3 (ru)
TW (1) TW438768B (ru)
WO (1) WO1998040346A1 (ru)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050020687A1 (en) * 1996-01-14 2005-01-27 Consiglio Nazionale Ricerche Methods of treating inflammatory and viral disorders by administering cyclopentenone compounds
US6525082B1 (en) 1997-12-11 2003-02-25 Takara Shuzo Co., Ltd. Apoptosis inducer
ES2228078T3 (es) * 1998-08-18 2005-04-01 Takara Bio Inc. Remedios o preventivos que contienen compuestos de ciclopentenona como ingrediente activo.
US6720415B2 (en) 1998-12-02 2004-04-13 Princeton University Compositions and methods for regulating bacterial pathogenesis
US7326542B2 (en) 1998-12-02 2008-02-05 Princeton University Compositions and methods for regulating bacterial pathogenesis
JP4171178B2 (ja) * 1999-02-19 2008-10-22 タカラバイオ株式会社 治療剤
AU3665700A (en) * 1999-03-22 2000-10-09 Charterhouse Therapeutics Ltd. Chemical compounds and their uses
WO2000062785A1 (fr) * 1999-04-15 2000-10-26 Takara Shuzo Co., Ltd. Remedes
GB9929702D0 (en) * 1999-12-16 2000-02-09 Charterhouse Therapeutics Ltd Chemical compounds and their uses
US6559176B1 (en) 2000-05-10 2003-05-06 Princeton University Compounds and methods for regulating bacterial growth and pathogenesis
CN106518643B (zh) * 2016-10-14 2019-02-15 宁波大学 一种环戊烯酮类化合物及其制备方法和用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0768163B2 (ja) * 1989-03-17 1995-07-26 財団法人野口研究所 シクロペンテノン誘導体の製法

Also Published As

Publication number Publication date
DE69809544T2 (de) 2003-10-02
US6136854A (en) 2000-10-24
EP0976717B1 (en) 2002-11-20
ES2183328T3 (es) 2003-03-16
CN1156432C (zh) 2004-07-07
EP0976717A4 (en) 2000-05-17
KR20000062429A (ko) 2000-10-25
CA2283634A1 (en) 1998-09-17
WO1998040346A1 (fr) 1998-09-17
JP3763585B2 (ja) 2006-04-05
DE69809544D1 (de) 2003-01-02
AU6117798A (en) 1998-09-29
AU730766B2 (en) 2001-03-15
KR100555843B1 (ko) 2006-03-03
EA001808B1 (ru) 2001-08-27
CN1247528A (zh) 2000-03-15
EP0976717A1 (en) 2000-02-02
TW438768B (en) 2001-06-07
ATE228110T1 (de) 2002-12-15

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM

PC4A Registration of transfer of a eurasian patent by assignment
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): RU