EA199900124A2 - Способ лечения сердечной недостаточности - Google Patents

Способ лечения сердечной недостаточности

Info

Publication number
EA199900124A2
EA199900124A2 EA199900124A EA199900124A EA199900124A2 EA 199900124 A2 EA199900124 A2 EA 199900124A2 EA 199900124 A EA199900124 A EA 199900124A EA 199900124 A EA199900124 A EA 199900124A EA 199900124 A2 EA199900124 A2 EA 199900124A2
Authority
EA
Eurasian Patent Office
Prior art keywords
heart failure
treating heart
phenoxy
trimethyl
dimethyl
Prior art date
Application number
EA199900124A
Other languages
English (en)
Other versions
EA199900124A3 (ru
Inventor
Юпинг Лианг Чен
Энтони Эндреа Фосса
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA199900124A2 publication Critical patent/EA199900124A2/ru
Publication of EA199900124A3 publication Critical patent/EA199900124A3/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Данное изобретение относится к способу лечения млекопитающего, страдающего сердечной недостаточностью, при котором млекопитающему вводят терапевтически эффективное количество 4-(1-этил-пропокси)-3,6-диметил-2-(2,4,6-триметил-фенокси)-пиридина и (3,6-диметил-2-(2,4,6-триметил-фенокси)-пиридин-4-ил)-(1-этил-пропил)-амина или их фармацевтически приемлемой соли. Данное изобретение также направлено на способы использования для лечения застойной сердечной недостаточности комбинаций этих двух агентов с другими соединениями для лечения застойной сердечной недостаточности.
EA199900124A 1998-02-17 1999-02-16 Способ лечениясердечной недостаточности EA199900124A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7493498P 1998-02-17 1998-02-17

Publications (2)

Publication Number Publication Date
EA199900124A2 true EA199900124A2 (ru) 1999-08-26
EA199900124A3 EA199900124A3 (ru) 1999-12-29

Family

ID=22122537

Family Applications (1)

Application Number Title Priority Date Filing Date
EA199900124A EA199900124A3 (ru) 1998-02-17 1999-02-16 Способ лечениясердечной недостаточности

Country Status (28)

Country Link
US (1) US6043260A (ru)
EP (1) EP0951906A1 (ru)
JP (1) JPH11292766A (ru)
KR (1) KR19990072616A (ru)
CN (1) CN1231176A (ru)
AP (1) AP9901464A0 (ru)
AR (1) AR017723A1 (ru)
AU (1) AU1732999A (ru)
BG (1) BG103180A (ru)
BR (1) BR9900653A (ru)
CA (1) CA2262252C (ru)
EA (1) EA199900124A3 (ru)
GT (1) GT199900015A (ru)
HR (1) HRP990054A2 (ru)
HU (1) HUP9900386A3 (ru)
ID (1) ID23218A (ru)
IL (1) IL128531A0 (ru)
IS (1) IS4975A (ru)
MA (1) MA26608A1 (ru)
NO (1) NO990722L (ru)
OA (1) OA10976A (ru)
PA (1) PA8467401A1 (ru)
PE (1) PE20000266A1 (ru)
PL (1) PL331507A1 (ru)
SG (1) SG81261A1 (ru)
TN (1) TNSN99024A1 (ru)
TR (1) TR199900328A2 (ru)
ZA (1) ZA991220B (ru)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956047B1 (en) 1995-06-06 2005-10-18 Pfizer Inc. Corticotropin releasing factor antagonists
US7067664B1 (en) 1995-06-06 2006-06-27 Pfizer Inc. Corticotropin releasing factor antagonists
US6403599B1 (en) 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
US6387894B1 (en) * 1999-06-11 2002-05-14 Pfizer Inc. Use of CRF antagonists and renin-angiotensin system inhibitors
EP1216037A2 (en) 1999-09-21 2002-06-26 Emory University Methods and compositions for treating platelet-related disorders using mpl pathway inhibitory agents
BR0107662A (pt) * 2000-01-18 2002-11-19 Pfizer Prod Inc Antagonistas do fator de liberação de corticotropina
US6737430B2 (en) 2000-11-09 2004-05-18 Pfizer, Inc. Mutual prodrug of amlodipine and atorvastatin
GB0027410D0 (en) * 2000-11-09 2000-12-27 Pfizer Ltd Mutual prodrug of amlodipine and atorvastatin
US6992087B2 (en) 2001-11-21 2006-01-31 Pfizer Inc Substituted aryl 1,4-pyrazine derivatives
US7015229B2 (en) 2002-02-22 2006-03-21 Pfizer Inc Substituted pyrimidinones and pyrimidinthiones
CA2478715A1 (en) * 2002-03-13 2003-09-25 Pharmacia & Upjohn Company Novel pyrazolo [1,5-a]pyridine derivatives and their use as neurotransmitter modulators
JP2005533014A (ja) * 2002-04-26 2005-11-04 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー 置換ピラジン誘導体
MXPA05002418A (es) * 2002-09-12 2005-05-27 Pharmacia & Upjohn Co Llc Derivados de 1,4-pirazina sustituidos.
AR041470A1 (es) * 2002-10-17 2005-05-18 Upjohn Co Compuestos de pirrolo (1,2 - b) piridazina y sus usos
MXPA05005408A (es) * 2002-11-21 2005-08-03 Pharmacia & Upjohn Co Llc Compuestos de pirazina como moduladores de factor de liberacion de corticotropina.
WO2004094408A1 (en) * 2003-04-23 2004-11-04 Pharmacia & Upjohn Company Llc Substituted pyrimidinones and pyrimidinthiones as crf antagonists
CA2523072A1 (en) * 2003-05-07 2004-11-18 Pharmacia & Upjohn Company Llc Pyrrolo (1,2-b) pyridazine compounds and their use as crf-1 receptor antagonists
JP2006525989A (ja) * 2003-05-09 2006-11-16 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Ｃｎｓ障害を治療するためのｃｒｆ１受容体アンタゴニストとしてのピラジノン
CA2524352A1 (en) * 2003-05-09 2004-11-18 Pharmacia & Upjohn Company Llc Substituted pyrimidine derivatives
CA2524519A1 (en) * 2003-05-09 2004-11-18 Pharmacia & Upjohn Company Llc Compounds as crf1 receptor antagonists
US20050209289A1 (en) * 2004-03-16 2005-09-22 Talarico Matthew T Method for vascular dysregulation
US20060211710A1 (en) * 2005-03-17 2006-09-21 Pfizer Inc Substituted aryl 1,4-pyrazine derivatives
US8338441B2 (en) 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW574214B (en) * 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
US6403599B1 (en) * 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
EP0795327A1 (en) * 1996-03-13 1997-09-17 Pfizer Inc. Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin

Also Published As

Publication number Publication date
AR017723A1 (es) 2001-09-12
CA2262252C (en) 2006-01-10
TNSN99024A1 (fr) 2005-11-10
HUP9900386A2 (hu) 1999-11-29
EP0951906A1 (en) 1999-10-27
US6043260A (en) 2000-03-28
PL331507A1 (en) 1999-08-30
PE20000266A1 (es) 2000-04-07
JPH11292766A (ja) 1999-10-26
BG103180A (bg) 1999-09-30
EA199900124A3 (ru) 1999-12-29
CN1231176A (zh) 1999-10-13
HU9900386D0 (en) 1999-04-28
SG81261A1 (en) 2001-06-19
GT199900015A (es) 2000-07-26
OA10976A (en) 2001-11-05
BR9900653A (pt) 2000-10-17
MA26608A1 (fr) 2004-12-20
NO990722D0 (no) 1999-02-16
ZA991220B (en) 2000-08-16
IS4975A (is) 1999-08-18
PA8467401A1 (es) 2000-09-29
IL128531A0 (en) 2000-01-31
HUP9900386A3 (en) 1999-12-28
HRP990054A2 (en) 2000-02-29
TR199900328A2 (xx) 1999-10-21
ID23218A (id) 2000-03-30
NO990722L (no) 1999-08-18
KR19990072616A (ko) 1999-09-27
AU1732999A (en) 1999-09-02
AP9901464A0 (en) 1999-03-31
CA2262252A1 (en) 1999-08-17

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