BR9900653A - Método para tratamento da insuficiência cardìaca - Google Patents

Método para tratamento da insuficiência cardìaca

Info

Publication number
BR9900653A
BR9900653A BR9900653-7A BR9900653A BR9900653A BR 9900653 A BR9900653 A BR 9900653A BR 9900653 A BR9900653 A BR 9900653A BR 9900653 A BR9900653 A BR 9900653A
Authority
BR
Brazil
Prior art keywords
heart failure
treating
treating heart
phenoxy
trimethyl
Prior art date
Application number
BR9900653-7A
Other languages
English (en)
Inventor
Yuhpyng Liang Chen
Anthony Andrea Fossa
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR9900653A publication Critical patent/BR9900653A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Patente de Invenção: <B>"MéTODO PARA TRATAMENTO DA INSUFICIêNCIA CARDìACA"<D>. Esta invenção refere-se a um método para tratamento de um mamífero que se apresenta com insuficiência cardíaca compreendendo a administração a um mamífero de uma quantidade terapeuticamente eficaz que inclui 4-(1-etil-propóxi)-3,6-dimetil-2-(2,4,6-trimetil-fenóxi)-piridina e (3,6-dimetil-2-(2,4,6-trimetil-fenóxi)-piridin-4-il)-(1-etil-propil)-amina ou um seu sal farmaceuticamente aceitável. Esta invenção é também dirigida para métodos de utilização de combinações destes dois agentes com outros compostos para tratamento da insuficiência cardíaca congestiva para tratamento da insuficiência cardíaca congestiva.
BR9900653-7A 1998-02-17 1999-02-12 Método para tratamento da insuficiência cardìaca BR9900653A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7493498P 1998-02-17 1998-02-17

Publications (1)

Publication Number Publication Date
BR9900653A true BR9900653A (pt) 2000-10-17

Family

ID=22122537

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9900653-7A BR9900653A (pt) 1998-02-17 1999-02-12 Método para tratamento da insuficiência cardìaca

Country Status (28)

Country Link
US (1) US6043260A (pt)
EP (1) EP0951906A1 (pt)
JP (1) JPH11292766A (pt)
KR (1) KR19990072616A (pt)
CN (1) CN1231176A (pt)
AP (1) AP9901464A0 (pt)
AR (1) AR017723A1 (pt)
AU (1) AU1732999A (pt)
BG (1) BG103180A (pt)
BR (1) BR9900653A (pt)
CA (1) CA2262252C (pt)
EA (1) EA199900124A3 (pt)
GT (1) GT199900015A (pt)
HR (1) HRP990054A2 (pt)
HU (1) HUP9900386A3 (pt)
ID (1) ID23218A (pt)
IL (1) IL128531A0 (pt)
IS (1) IS4975A (pt)
MA (1) MA26608A1 (pt)
NO (1) NO990722L (pt)
OA (1) OA10976A (pt)
PA (1) PA8467401A1 (pt)
PE (1) PE20000266A1 (pt)
PL (1) PL331507A1 (pt)
SG (1) SG81261A1 (pt)
TN (1) TNSN99024A1 (pt)
TR (1) TR199900328A2 (pt)
ZA (1) ZA991220B (pt)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6403599B1 (en) 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
US7067664B1 (en) 1995-06-06 2006-06-27 Pfizer Inc. Corticotropin releasing factor antagonists
US6956047B1 (en) 1995-06-06 2005-10-18 Pfizer Inc. Corticotropin releasing factor antagonists
US6387894B1 (en) * 1999-06-11 2002-05-14 Pfizer Inc. Use of CRF antagonists and renin-angiotensin system inhibitors
AU3885901A (en) * 1999-09-21 2001-04-24 Emory University Methods and compositions for treating platelet-related disorders
BR0107662A (pt) * 2000-01-18 2002-11-19 Pfizer Prod Inc Antagonistas do fator de liberação de corticotropina
GB0027410D0 (en) * 2000-11-09 2000-12-27 Pfizer Ltd Mutual prodrug of amlodipine and atorvastatin
US6737430B2 (en) 2000-11-09 2004-05-18 Pfizer, Inc. Mutual prodrug of amlodipine and atorvastatin
US6992087B2 (en) 2001-11-21 2006-01-31 Pfizer Inc Substituted aryl 1,4-pyrazine derivatives
AU2003215379A1 (en) 2002-02-22 2003-09-09 Pharmacia And Upjohn Company Substituted pyrimidinones and pyrimidinthiones
BR0308391A (pt) * 2002-03-13 2005-01-11 Pharmacia & Upjohn Co Llc Derivados de pirazolo(1,5-a)piridina como moduladores neurotransmissores
EP1499599A1 (en) * 2002-04-26 2005-01-26 Pharmacia & Upjohn Company LLC Substituted pyrazine derivatives
EP1539736A1 (en) * 2002-09-12 2005-06-15 Pharmacia & Upjohn Company LLC Substituted 1,4-pyrazine derivatives
AR041470A1 (es) * 2002-10-17 2005-05-18 Upjohn Co Compuestos de pirrolo (1,2 - b) piridazina y sus usos
MXPA05005408A (es) * 2002-11-21 2005-08-03 Pharmacia & Upjohn Co Llc Compuestos de pirazina como moduladores de factor de liberacion de corticotropina.
EP1620428A1 (en) * 2003-04-23 2006-02-01 Pharmacia & Upjohn Company LLC Substituted pyrimidinones and pyrimidinthiones as crf antagonists
EP1622911A2 (en) * 2003-05-07 2006-02-08 Pharmacia & Upjohn Company LLC Pyrrolo[1,2-b]pyridazine compounds and their use as crf-1 receptor antagonists
MXPA05012087A (es) * 2003-05-09 2006-02-22 Pharmacia & Upjohn Co Llc Nuevas pirazinonas como antagonistas del receptor crf1.
JP2006525993A (ja) * 2003-05-09 2006-11-16 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー Ｃｒｆ１受容体拮抗剤である化合物
MXPA05012081A (es) * 2003-05-09 2006-02-22 Pharmacia & Upjohn Co Llc Derivados de pirimidina sustituidos.
WO2005089639A2 (en) * 2004-03-16 2005-09-29 Talarico M D Matthew T Method for vascular dysregulation
US20060211710A1 (en) * 2005-03-17 2006-09-21 Pfizer Inc Substituted aryl 1,4-pyrazine derivatives
US8338441B2 (en) * 2009-05-15 2012-12-25 Gilead Sciences, Inc. Inhibitors of human immunodeficiency virus replication

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW574214B (en) * 1994-06-08 2004-02-01 Pfizer Corticotropin releasing factor antagonists
US6403599B1 (en) * 1995-11-08 2002-06-11 Pfizer Inc Corticotropin releasing factor antagonists
EP0795327A1 (en) * 1996-03-13 1997-09-17 Pfizer Inc. Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin

Also Published As

Publication number Publication date
AR017723A1 (es) 2001-09-12
TR199900328A2 (xx) 1999-10-21
PE20000266A1 (es) 2000-04-07
NO990722L (no) 1999-08-18
TNSN99024A1 (fr) 2005-11-10
IL128531A0 (en) 2000-01-31
SG81261A1 (en) 2001-06-19
KR19990072616A (ko) 1999-09-27
AP9901464A0 (en) 1999-03-31
CA2262252A1 (en) 1999-08-17
PL331507A1 (en) 1999-08-30
HRP990054A2 (en) 2000-02-29
GT199900015A (es) 2000-07-26
CN1231176A (zh) 1999-10-13
ZA991220B (en) 2000-08-16
AU1732999A (en) 1999-09-02
IS4975A (is) 1999-08-18
OA10976A (en) 2001-11-05
PA8467401A1 (es) 2000-09-29
EP0951906A1 (en) 1999-10-27
HUP9900386A3 (en) 1999-12-28
CA2262252C (en) 2006-01-10
HU9900386D0 (en) 1999-04-28
JPH11292766A (ja) 1999-10-26
HUP9900386A2 (hu) 1999-11-29
EA199900124A2 (ru) 1999-08-26
ID23218A (id) 2000-03-30
BG103180A (bg) 1999-09-30
EA199900124A3 (ru) 1999-12-29
US6043260A (en) 2000-03-28
MA26608A1 (fr) 2004-12-20
NO990722D0 (no) 1999-02-16

Similar Documents

Publication Publication Date Title
BR9900653A (pt) Método para tratamento da insuficiência cardìaca
MXPA03006855A (es) Metodo para tratar insuficiencia cardiaca cronica y/o niveles elevados de colesterol, utilizando acido 3,5-diyodotiropropionico, y metodo para su preparacion.
YU59103A (sh) Upotreba supstituisanih jedinjenja azetidinona za lečenje sitosterolemije
BR9812030A (pt) Combinações terapêuticas compreendendo amlodipina e atorvastatina
BR0110420A (pt) Agonistas muscarìnicos
BR0213242A (pt) Composto ou um seu sal ou solvato, composto e seus sais de adição de ácido fisiologicamente aceitáveis, composição farmacêutica, método de tratamento de um ou mais distúrbios, uso de um composto, e, processo de preparação de um composto
PL333920A1 (en) 3-pyridyl enantiomers and their application as pain-relieving agents
BR9811558A (pt) Terapêutica combinada compreendendo um composto amlodipina e uma estatina
BR9908510A (pt) Uso de um composto, composto, processo para a preparação de um composto, composição farmacêutica, e, processo de tratar um paciente que sofre de, ou em risco de, uma doença micobacteriana
BR0012175A (pt) Antagonistas de receptor de igiur5, seletivos para o tratamento de enxaqueca
BR0316458A (pt) Composto, composição farmacêutica, método de tratamento ou prevenção de doenças, método para intensificar a cognição em um paciente saudável, e, uso de um composto
BR9910329A (pt) Composto, composição farmacêutica, processo para estimular a liberação do hormÈnio de crescimento da pituitária de um mamìfero, e, uso de um composto
EA200000693A1 (ru) Антагонисты хемокинного рецептора и способы их применения
DE69621786T2 (de) Aminotetralinderivat zur behandlung von herzkreislauferkrankung
PL354961A1 (en) Prevention and treatment of diseases associated with blood coagulation
ECSP992840A (es) Procedimiento para tratar la insuficiencia cardiaca
PT1156795E (pt) Utilizacao de acido succinico ou de seus sais e metodo de tratamento da resistencia a insulina
BR9808305A (pt) Forma hidratada cristalina, processo para a preparação da forma hidratada cristalina, composição farmacêutica, processo de tratamento de um mamìfero, e, processo de tratamento ou de prevenção de dor.
BR9911150A (pt) Método de tratamento
HRP20080389A2 (en) THE USE OF R(+)-α-(2,3-DIMETHOXYPHENYL)-1-[2-(4-FLUOROPHENYL)ETHYL]-4-PIPERIDINEMETHANOL FOR THE TREATMENT OF SLEEP DISORDERS
BR0115618A (pt) Derivados de indol e diidroindol
GT200100066A (es) Agente hipertensivo y su uso.
NO994712L (no) FremgangsmÕte og sammensetninger for behandling av AIDS- tilknyttet Kaposi-sarkom

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10(VIII), 13, 24 E 25 DA LPI

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.