EA031990B1 - МУТАНТНЫЕ ПОЛИПЕПТИДЫ TGFβ И ИХ ПРИМЕНЕНИЕ - Google Patents
МУТАНТНЫЕ ПОЛИПЕПТИДЫ TGFβ И ИХ ПРИМЕНЕНИЕ Download PDFInfo
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- EA031990B1 EA031990B1 EA201590914A EA201590914A EA031990B1 EA 031990 B1 EA031990 B1 EA 031990B1 EA 201590914 A EA201590914 A EA 201590914A EA 201590914 A EA201590914 A EA 201590914A EA 031990 B1 EA031990 B1 EA 031990B1
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| CU20120158A CU24181B1 (es) | 2012-11-09 | 2012-11-09 | POLIPÉPTIDOS DERIVADOS DEL TGFß |
| PCT/CU2013/000007 WO2014071894A1 (es) | 2012-11-09 | 2013-10-30 | POLIPÉPTIDOS DERIVADOS DEL TGFβ Y SUS USOS |
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| EA201590914A1 EA201590914A1 (ru) | 2015-09-30 |
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| EA201590914A EA031990B1 (ru) | 2012-11-09 | 2013-10-30 | МУТАНТНЫЕ ПОЛИПЕПТИДЫ TGFβ И ИХ ПРИМЕНЕНИЕ |
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| WO2018094173A1 (en) * | 2016-11-18 | 2018-05-24 | University Of Pittsburgh-Of The Commonwealth System Of Higher Education | Engineered tgf-beta monomers and their use for inhibiting tgf-beta signaling |
| PL238850B1 (pl) * | 2017-10-19 | 2021-10-11 | Calther Polska Spolka Z Ograniczona Odpowiedzialnoscia | Aktywna forma transformującego czynnika wzrostu beta 1 (TGFβ1) do zastosowania w leczeniu pacjentów z glejakami wielopostaciowymi, w przypadku których to glejaków ponad 5% komórek nowotworowych jest EGFRvIII-pozytywna |
| CN119285746A (zh) * | 2024-10-24 | 2025-01-10 | 湖南中晟全肽生物科技股份有限公司 | 作为TGF-β受体激动剂肽的化合物及其用途 |
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| WO1999065948A1 (en) * | 1998-06-16 | 1999-12-23 | Biogen, Inc. | Variant type ii tgf-beta receptor fusion proteins and methods |
| US20070244042A1 (en) * | 2004-09-28 | 2007-10-18 | The Board Of Regents Of The University Of Texas System | Antagonizing TGF-beta activity with various ectodomains of TGF-beta receptors used in combination or as fusion proteins |
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| AU778998B2 (en) | 1998-09-22 | 2004-12-23 | University Of Maryland At Baltimore | Cystine knot growth factor mutants |
| US6677432B1 (en) * | 1998-10-07 | 2004-01-13 | Stryker Corporation | Mutations of the C-terminal portion of TGF-β superfamily proteins |
| ES2146552B1 (es) | 1998-11-24 | 2001-04-16 | Inst Cientifico Tecnol Navarra | Peptidos inhibidores de tgf/31 |
| CA2575278A1 (en) * | 2004-06-30 | 2006-01-19 | Molecular Logix, Inc. | Epidermal growth factor receptor antagonists and methods of use |
| CN101365712A (zh) * | 2005-01-11 | 2009-02-11 | 莫勒丘尔洛吉克斯有限公司 | Pan-HER拮抗剂及其使用方法 |
| GB0724051D0 (en) * | 2007-12-08 | 2008-01-16 | Medical Res Council | Mutant proteins and methods for producing them |
| CA2796706A1 (en) * | 2010-04-22 | 2011-10-27 | The Medical Research, Infrastructure, And Health Services Fund Of The Te L Aviv Medical Center | High affinity leptins and leptin antagonists |
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| US20070244042A1 (en) * | 2004-09-28 | 2007-10-18 | The Board Of Regents Of The University Of Texas System | Antagonizing TGF-beta activity with various ectodomains of TGF-beta receptors used in combination or as fusion proteins |
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