EA020779B1 - СПОСОБ ЛЕЧЕНИЯ РАКА С ИСПОЛЬЗОВАНИЕМ ИНГИБИТОРА cMET И AXL И ИНГИБИТОРА ErbB - Google Patents
СПОСОБ ЛЕЧЕНИЯ РАКА С ИСПОЛЬЗОВАНИЕМ ИНГИБИТОРА cMET И AXL И ИНГИБИТОРА ErbB Download PDFInfo
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- EA020779B1 EA020779B1 EA201071268A EA201071268A EA020779B1 EA 020779 B1 EA020779 B1 EA 020779B1 EA 201071268 A EA201071268 A EA 201071268A EA 201071268 A EA201071268 A EA 201071268A EA 020779 B1 EA020779 B1 EA 020779B1
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- Eurasian Patent Office
- Prior art keywords
- compound
- lapatinib
- inhibitor
- ebb
- combination
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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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Landscapes
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| JP5688877B2 (ja) | 2005-11-11 | 2015-03-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 癌疾患の治療用キナゾリン誘導体 |
| DK2387563T4 (da) | 2009-01-16 | 2022-07-18 | Exelixis Inc | Malatsalt af n-(4-{ [ 6, 7-bis(methyloxy)quinolin-4-yl]oxy}phenyl-n'-(4-fluorphenyl)cyclopropan-1,1-dicarboxamid, og krystallinske former deraf til behandling af cancer |
| RU2568066C2 (ru) | 2009-03-25 | 2015-11-10 | Дженентек, Инк. | Антитела против fgfr3 и способы их применения |
| JP5963672B2 (ja) | 2009-07-06 | 2016-08-03 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | Ｂｉｂｗ２９９２、その塩及びこの活性成分を含む固体医薬製剤の乾燥方法 |
| TW201106972A (en) * | 2009-07-27 | 2011-03-01 | Genentech Inc | Combination treatments |
| WO2011014872A2 (en) * | 2009-07-31 | 2011-02-03 | The Johns Hopkins University | Compositions and methods for diagnosing, treating or preventing neoplasias |
| UA108618C2 (uk) | 2009-08-07 | 2015-05-25 | Застосування c-met-модуляторів в комбінації з темозоломідом та/або променевою терапією для лікування раку | |
| LT2719708T (lt) * | 2009-11-13 | 2018-02-12 | Daiichi Sankyo Europe Gmbh | Medžiaga ir būdai, skirti su her-3 susijusių ligų gydymui arba prevencijai |
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| FI2621481T4 (fi) | 2010-09-27 | 2023-01-13 | Met- ja vegf-kaksoisestäjiä kastraatioresistentin eturauhassyövän ja osteoblastisten luun etäispesäkkeiden hoitamiseen | |
| SG10201510086VA (en) * | 2010-12-23 | 2016-01-28 | Nestec Sa | Drug selection for malignant cancer therapy using antibody-based arrays |
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| ATE290882T1 (de) * | 2001-01-16 | 2005-04-15 | Glaxo Group Ltd | Pharmazeutische mischung gegen krebs, die ein 4- chinazolinamin in kombination mit paclitaxel, carboplatin or vinorelbine enthält |
| ITRM20030475A1 (it) * | 2003-10-15 | 2005-04-16 | Sipa Societa Industrializzazione P Rogettazione E | Impianto e metodo per il condizionamento termico di oggetti |
| UA96139C2 (uk) * | 2005-11-08 | 2011-10-10 | Дженентек, Інк. | Антитіло до нейропіліну-1 (nrp1) |
| US20090123474A1 (en) * | 2005-12-15 | 2009-05-14 | Astrazeneca Ab | Combination of angiopoietin-2 antagonist and of vegf-a, kdr and/or fltl antagonist for treating cancer |
| CN105106199A (zh) * | 2006-12-14 | 2015-12-02 | 埃克塞利希斯股份有限公司 | 使用mek抑制剂的方法 |
| EP2851091B1 (en) * | 2007-04-13 | 2017-12-27 | Dana-Farber Cancer Institute, Inc. | Methods for treating cancer resistant to ERBB therapeutics |
| CN101743253B (zh) * | 2007-05-17 | 2013-05-08 | 健泰科生物技术公司 | 神经毡蛋白片段与神经毡蛋白抗体复合物的晶体结构 |
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Also Published As
| Publication number | Publication date |
|---|---|
| US20130150363A1 (en) | 2013-06-13 |
| JP2011519941A (ja) | 2011-07-14 |
| AU2009244453B2 (en) | 2012-07-19 |
| CL2009001063A1 (es) | 2010-09-24 |
| TW201006829A (en) | 2010-02-16 |
| PE20091832A1 (es) | 2009-12-25 |
| CN102083824A (zh) | 2011-06-01 |
| EA201071268A1 (ru) | 2011-06-30 |
| US20090274693A1 (en) | 2009-11-05 |
| KR20110004462A (ko) | 2011-01-13 |
| US20130142790A1 (en) | 2013-06-06 |
| AU2009244453A1 (en) | 2009-11-12 |
| EP2274304A1 (en) | 2011-01-19 |
| BRPI0912582A2 (pt) | 2015-07-28 |
| UY31800A (es) | 2009-11-10 |
| IL209057A0 (en) | 2011-01-31 |
| WO2009137429A1 (en) | 2009-11-12 |
| CA2723699A1 (en) | 2009-11-12 |
| ZA201007722B (en) | 2011-08-31 |
| AR071631A1 (es) | 2010-06-30 |
| MX2010012101A (es) | 2010-11-30 |
| SG190623A1 (en) | 2013-06-28 |
| EP2274304A4 (en) | 2012-05-30 |
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