HUE054883T2 - N-{5-[(6,7-dimetoxi-4-kinolinil)oxi]-2-piridinil}-2,5-dioxo-1-fenil-1,2,5,6,7,8-hexahidro-3-kinolinkarboxamid etánszulfonát sója - Google Patents
N-{5-[(6,7-dimetoxi-4-kinolinil)oxi]-2-piridinil}-2,5-dioxo-1-fenil-1,2,5,6,7,8-hexahidro-3-kinolinkarboxamid etánszulfonát sójaInfo
- Publication number
- HUE054883T2 HUE054883T2 HUE18744970A HUE18744970A HUE054883T2 HU E054883 T2 HUE054883 T2 HU E054883T2 HU E18744970 A HUE18744970 A HU E18744970A HU E18744970 A HUE18744970 A HU E18744970A HU E054883 T2 HUE054883 T2 HU E054883T2
- Authority
- HU
- Hungary
- Prior art keywords
- quinolinecarboxamide
- hexahydro
- dioxo
- quinolinyl
- pyridinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017011835 | 2017-01-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE054883T2 true HUE054883T2 (hu) | 2021-10-28 |
Family
ID=62979439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE18744970A HUE054883T2 (hu) | 2017-01-26 | 2018-01-25 | N-{5-[(6,7-dimetoxi-4-kinolinil)oxi]-2-piridinil}-2,5-dioxo-1-fenil-1,2,5,6,7,8-hexahidro-3-kinolinkarboxamid etánszulfonát sója |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10836747B2 (hu) |
| EP (1) | EP3575293B1 (hu) |
| JP (1) | JP6605763B2 (hu) |
| KR (1) | KR102571911B1 (hu) |
| CN (1) | CN110225908A (hu) |
| AU (1) | AU2018211801B2 (hu) |
| BR (1) | BR112019015352A2 (hu) |
| CA (1) | CA3051605C (hu) |
| DK (1) | DK3575293T3 (hu) |
| ES (1) | ES2872923T3 (hu) |
| HU (1) | HUE054883T2 (hu) |
| IL (1) | IL268221B (hu) |
| MX (1) | MX2019008787A (hu) |
| MY (1) | MY196680A (hu) |
| PH (1) | PH12019501693A1 (hu) |
| PL (1) | PL3575293T3 (hu) |
| PT (1) | PT3575293T (hu) |
| RU (1) | RU2019123279A (hu) |
| SG (1) | SG11201906819VA (hu) |
| TW (1) | TWI779007B (hu) |
| WO (1) | WO2018139527A1 (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3673907A4 (en) * | 2017-08-23 | 2020-08-19 | ONO Pharmaceutical Co., Ltd. | CANCER TREATMENT PHARMACEUTICAL INCLUDING AX1 INHIBITOR AS AN EFFECTIVE INGREDIENT |
| WO2019074116A1 (ja) | 2017-10-13 | 2019-04-18 | 小野薬品工業株式会社 | Ａｘｌ阻害剤を有効成分として含む固形がん治療剤 |
| CN117624128A (zh) * | 2022-08-30 | 2024-03-01 | 药捷安康(南京)科技股份有限公司 | 喹啉衍生物抑制剂的晶型及其制备方法及用途 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020048610A1 (en) * | 2000-01-07 | 2002-04-25 | Cima Michael J. | High-throughput formation, identification, and analysis of diverse solid-forms |
| US6428234B1 (en) * | 2000-01-07 | 2002-08-06 | Closure Medical Corporation | Adhesive applicator tips with improved flow properties |
| JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
| WO2007033196A1 (en) | 2005-09-14 | 2007-03-22 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| JP2009537632A (ja) | 2006-05-19 | 2009-10-29 | バイエル・ヘルスケア・アクチェンゲゼルシャフト | 過剰増殖性障害および血管新生障害の処置に有用なピリドンカルボキサミド誘導体 |
| CA2655128A1 (en) | 2006-06-08 | 2007-12-21 | Array Biopharma Inc. | Quinoline compounds and methods of use |
| CA2718538A1 (en) | 2008-04-16 | 2009-10-22 | Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften E.V. | Quinoline derivatives as axl kinase inhibitors |
| UY31800A (es) | 2008-05-05 | 2009-11-10 | Smithkline Beckman Corp | Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb |
| MX2010012290A (es) | 2008-05-14 | 2011-02-21 | Amgen Inc | Combinaciones de inhibidores del receptor del factor de crecimiento endotelial vascular e inhibidores del factor de crecimiento de hepatocito para el tratamiento de cancer. |
| US20110229469A1 (en) | 2008-10-01 | 2011-09-22 | Ludwig Institute For Cancer Research | Methods for the treatment of cancer |
| JP2010178651A (ja) | 2009-02-04 | 2010-08-19 | Eisai R & D Management Co Ltd | Ｈｇｆｒ阻害物質の作用検定方法 |
| JP5525612B2 (ja) | 2010-07-23 | 2014-06-18 | 国立大学法人 東京大学 | 含窒素複素環誘導体 |
| JP5791412B2 (ja) | 2010-07-26 | 2015-10-07 | 日本碍子株式会社 | セラミックヒーター |
| EP2423208A1 (en) | 2010-08-28 | 2012-02-29 | Lead Discovery Center GmbH | Pharmaceutically active compounds as Axl inhibitors |
| EP2651405A2 (en) | 2010-12-14 | 2013-10-23 | Electrophoretics Limited | Casein kinase 1 (ck1 ) inhibitors |
| CN102816175B (zh) | 2011-06-09 | 2015-12-16 | 上海汇伦生命科技有限公司 | 一种杂环并吡啶酮类化合物,其中间体、制备方法和用途 |
| JP2013074633A (ja) | 2011-09-26 | 2013-04-22 | Oki Electric Ind Co Ltd | スイッチング電源装置及び現金自動預け払い装置 |
| CN103958497B (zh) | 2011-11-14 | 2017-09-01 | 亚尼塔公司 | 作为AXL和c‑MET激酶抑制剂的尿嘧啶衍生物 |
| TWI649308B (zh) | 2013-07-24 | 2019-02-01 | 小野藥品工業股份有限公司 | 喹啉衍生物 |
-
2018
- 2018-01-25 KR KR1020197021641A patent/KR102571911B1/ko active IP Right Grant
- 2018-01-25 PT PT187449707T patent/PT3575293T/pt unknown
- 2018-01-25 CN CN201880008442.7A patent/CN110225908A/zh active Pending
- 2018-01-25 EP EP18744970.7A patent/EP3575293B1/en active Active
- 2018-01-25 TW TW107102692A patent/TWI779007B/zh active
- 2018-01-25 US US16/480,514 patent/US10836747B2/en active Active
- 2018-01-25 BR BR112019015352-7A patent/BR112019015352A2/pt active Search and Examination
- 2018-01-25 WO PCT/JP2018/002250 patent/WO2018139527A1/ja active Application Filing
- 2018-01-25 SG SG11201906819VA patent/SG11201906819VA/en unknown
- 2018-01-25 CA CA3051605A patent/CA3051605C/en active Active
- 2018-01-25 AU AU2018211801A patent/AU2018211801B2/en active Active
- 2018-01-25 PL PL18744970T patent/PL3575293T3/pl unknown
- 2018-01-25 HU HUE18744970A patent/HUE054883T2/hu unknown
- 2018-01-25 DK DK18744970.7T patent/DK3575293T3/da active
- 2018-01-25 JP JP2018564622A patent/JP6605763B2/ja active Active
- 2018-01-25 MY MYPI2019004265A patent/MY196680A/en unknown
- 2018-01-25 MX MX2019008787A patent/MX2019008787A/es unknown
- 2018-01-25 RU RU2019123279A patent/RU2019123279A/ru unknown
- 2018-01-25 ES ES18744970T patent/ES2872923T3/es active Active
-
2019
- 2019-07-22 IL IL268221A patent/IL268221B/en unknown
- 2019-07-23 PH PH12019501693A patent/PH12019501693A1/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP3575293A1 (en) | 2019-12-04 |
| RU2019123279A (ru) | 2021-02-26 |
| KR102571911B1 (ko) | 2023-08-28 |
| WO2018139527A1 (ja) | 2018-08-02 |
| SG11201906819VA (en) | 2019-08-27 |
| BR112019015352A2 (pt) | 2020-03-10 |
| US20190389837A1 (en) | 2019-12-26 |
| PT3575293T (pt) | 2021-05-25 |
| PH12019501693A1 (en) | 2020-06-15 |
| MX2019008787A (es) | 2019-09-11 |
| CN110225908A (zh) | 2019-09-10 |
| DK3575293T3 (da) | 2021-04-26 |
| EP3575293B1 (en) | 2021-03-10 |
| JP6605763B2 (ja) | 2019-11-13 |
| EP3575293A4 (en) | 2019-12-04 |
| RU2019123279A3 (hu) | 2021-03-31 |
| JPWO2018139527A1 (ja) | 2019-06-27 |
| MY196680A (en) | 2023-04-29 |
| AU2018211801A1 (en) | 2019-08-15 |
| PL3575293T3 (pl) | 2021-09-06 |
| US10836747B2 (en) | 2020-11-17 |
| IL268221A (en) | 2019-09-26 |
| KR20190111035A (ko) | 2019-10-01 |
| TW201833099A (zh) | 2018-09-16 |
| TWI779007B (zh) | 2022-10-01 |
| IL268221B (en) | 2022-03-01 |
| ES2872923T3 (es) | 2021-11-03 |
| WO2018139527A9 (ja) | 2018-09-20 |
| CA3051605C (en) | 2024-06-25 |
| AU2018211801B2 (en) | 2021-07-08 |
| CA3051605A1 (en) | 2018-08-02 |
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