PL3575293T3 - Sól etanosulfonianowa n-{5-[(6,7-dimetoksy-4-chinolinyl)oksy]- 2-pirydy-nylo}-2,5-diokso-1-fenylo-1,2,5,6,7,8-heksahydro-3-chinolinokarboksamidu - Google Patents
Sól etanosulfonianowa n-{5-[(6,7-dimetoksy-4-chinolinyl)oksy]- 2-pirydy-nylo}-2,5-diokso-1-fenylo-1,2,5,6,7,8-heksahydro-3-chinolinokarboksamiduInfo
- Publication number
- PL3575293T3 PL3575293T3 PL18744970T PL18744970T PL3575293T3 PL 3575293 T3 PL3575293 T3 PL 3575293T3 PL 18744970 T PL18744970 T PL 18744970T PL 18744970 T PL18744970 T PL 18744970T PL 3575293 T3 PL3575293 T3 PL 3575293T3
- Authority
- PL
- Poland
- Prior art keywords
- quinolinecarboxamide
- hexahydro
- dioxo
- quinolinyl
- pyridinyl
- Prior art date
Links
- -1 6,7-dimethoxy-4-quinolinyl Chemical group 0.000 title 1
- CCIVGXIOQKPBKL-UHFFFAOYSA-N ethanesulfonic acid Chemical class CCS(O)(=O)=O CCIVGXIOQKPBKL-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/01—Sulfonic acids
- C07C309/02—Sulfonic acids having sulfo groups bound to acyclic carbon atoms
- C07C309/03—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C309/04—Sulfonic acids having sulfo groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton containing only one sulfo group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2017011835 | 2017-01-26 | ||
| PCT/JP2018/002250 WO2018139527A1 (ja) | 2017-01-26 | 2018-01-25 | キノリン誘導体のエタンスルホン酸塩 |
| EP18744970.7A EP3575293B1 (en) | 2017-01-26 | 2018-01-25 | Ethanesulfonate salt of n-{5-[(6,7-dimethoxy-4-quinolinyl)oxy]-2-pyridinyl}-2,5-dioxo-1-phenyl-1,2,5,6,7,8-hexahydro-3-quinolinecarboxamide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3575293T3 true PL3575293T3 (pl) | 2021-09-06 |
Family
ID=62979439
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL18744970T PL3575293T3 (pl) | 2017-01-26 | 2018-01-25 | Sól etanosulfonianowa n-{5-[(6,7-dimetoksy-4-chinolinyl)oksy]- 2-pirydy-nylo}-2,5-diokso-1-fenylo-1,2,5,6,7,8-heksahydro-3-chinolinokarboksamidu |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US10836747B2 (pl) |
| EP (1) | EP3575293B1 (pl) |
| JP (1) | JP6605763B2 (pl) |
| KR (1) | KR102571911B1 (pl) |
| CN (2) | CN119707932A (pl) |
| AU (1) | AU2018211801B2 (pl) |
| CA (1) | CA3051605C (pl) |
| DK (1) | DK3575293T3 (pl) |
| ES (1) | ES2872923T3 (pl) |
| HU (1) | HUE054883T2 (pl) |
| IL (1) | IL268221B (pl) |
| MX (1) | MX379140B (pl) |
| MY (1) | MY196680A (pl) |
| PH (1) | PH12019501693A1 (pl) |
| PL (1) | PL3575293T3 (pl) |
| PT (1) | PT3575293T (pl) |
| RU (1) | RU2019123279A (pl) |
| SG (1) | SG11201906819VA (pl) |
| TW (1) | TWI779007B (pl) |
| WO (1) | WO2018139527A1 (pl) |
| ZA (1) | ZA201904895B (pl) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3673907A4 (en) * | 2017-08-23 | 2020-08-19 | ONO Pharmaceutical Co., Ltd. | CANCER TREATMENT PHARMACEUTICAL INCLUDING AX1 INHIBITOR AS AN EFFECTIVE INGREDIENT |
| WO2019074116A1 (ja) | 2017-10-13 | 2019-04-18 | 小野薬品工業株式会社 | Ａｘｌ阻害剤を有効成分として含む固形がん治療剤 |
| KR20250053959A (ko) * | 2022-08-30 | 2025-04-22 | 트랜스테라 사이언시즈 (난징), 인크. | 퀴놀린 유도체 억제제의 결정형 및 이의 제조 방법과 용도 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6428234B1 (en) * | 2000-01-07 | 2002-08-06 | Closure Medical Corporation | Adhesive applicator tips with improved flow properties |
| CZ20022332A3 (cs) * | 2000-01-07 | 2003-01-15 | Transform Pharmaceuticals, Inc. | Sestava vzorků |
| JO2787B1 (en) | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
| WO2007033196A1 (en) | 2005-09-14 | 2007-03-22 | Bristol-Myers Squibb Company | Met kinase inhibitors |
| US20090306103A1 (en) | 2006-05-19 | 2009-12-10 | Stephen Boyer | Pyridonecarboxamide derivatives useful in treating hyper-proliferative and angiogenesis disorders |
| US20110053931A1 (en) | 2006-06-08 | 2011-03-03 | John Gaudino | Quinoline compounds and methods of use |
| MX2010011224A (es) | 2008-04-16 | 2011-02-25 | Max Planck Ges Zur Fa Rderung Der Wissenschaften E V | Derivados de quinoleina como inhibidores de la cinasa axl. |
| UY31800A (es) | 2008-05-05 | 2009-11-10 | Smithkline Beckman Corp | Metodo de tratamiento de cancer usando un inhibidor de cmet y axl y un inhibidor de erbb |
| US20110104161A1 (en) | 2008-05-14 | 2011-05-05 | Burgess Teresa L | Combinations vegf(r) inhibitors and hepatocyte growth factor (c-met) inhibitors for the treatment of cancer |
| MX2011003363A (es) | 2008-10-01 | 2011-04-27 | Ludwig Inst Cancer Res | Metodos para el tratamiento de cancer. |
| JP2010178651A (ja) | 2009-02-04 | 2010-08-19 | Eisai R & D Management Co Ltd | Ｈｇｆｒ阻害物質の作用検定方法 |
| WO2012011548A1 (ja) | 2010-07-23 | 2012-01-26 | 国立大学法人 東京大学 | 含窒素複素環誘導体 |
| JP5791412B2 (ja) | 2010-07-26 | 2015-10-07 | 日本碍子株式会社 | セラミックヒーター |
| EP2423208A1 (en) | 2010-08-28 | 2012-02-29 | Lead Discovery Center GmbH | Pharmaceutically active compounds as Axl inhibitors |
| JP5937102B2 (ja) | 2010-12-14 | 2016-06-22 | エレクトロフォレティクス リミテッド | カゼインキナーゼ１デルタ（ｃｋ１デルタ）阻害剤 |
| CN102816175B (zh) | 2011-06-09 | 2015-12-16 | 上海汇伦生命科技有限公司 | 一种杂环并吡啶酮类化合物,其中间体、制备方法和用途 |
| JP2013074633A (ja) | 2011-09-26 | 2013-04-22 | Oki Electric Ind Co Ltd | スイッチング電源装置及び現金自動預け払い装置 |
| SG10201510307WA (en) | 2011-11-14 | 2016-01-28 | Cephalon Inc | Uracil derivatives as axl and c-met kinase inhibitors |
| TWI649308B (zh) * | 2013-07-24 | 2019-02-01 | 小野藥品工業股份有限公司 | 喹啉衍生物 |
-
2018
- 2018-01-25 CN CN202411731946.5A patent/CN119707932A/zh active Pending
- 2018-01-25 DK DK18744970.7T patent/DK3575293T3/da active
- 2018-01-25 ES ES18744970T patent/ES2872923T3/es active Active
- 2018-01-25 CN CN201880008442.7A patent/CN110225908A/zh active Pending
- 2018-01-25 AU AU2018211801A patent/AU2018211801B2/en active Active
- 2018-01-25 MY MYPI2019004265A patent/MY196680A/en unknown
- 2018-01-25 TW TW107102692A patent/TWI779007B/zh active
- 2018-01-25 CA CA3051605A patent/CA3051605C/en active Active
- 2018-01-25 RU RU2019123279A patent/RU2019123279A/ru unknown
- 2018-01-25 US US16/480,514 patent/US10836747B2/en active Active
- 2018-01-25 KR KR1020197021641A patent/KR102571911B1/ko active Active
- 2018-01-25 PL PL18744970T patent/PL3575293T3/pl unknown
- 2018-01-25 WO PCT/JP2018/002250 patent/WO2018139527A1/ja not_active Ceased
- 2018-01-25 PT PT187449707T patent/PT3575293T/pt unknown
- 2018-01-25 HU HUE18744970A patent/HUE054883T2/hu unknown
- 2018-01-25 MX MX2019008787A patent/MX379140B/es unknown
- 2018-01-25 SG SG11201906819VA patent/SG11201906819VA/en unknown
- 2018-01-25 JP JP2018564622A patent/JP6605763B2/ja active Active
- 2018-01-25 EP EP18744970.7A patent/EP3575293B1/en active Active
-
2019
- 2019-07-22 IL IL268221A patent/IL268221B/en unknown
- 2019-07-23 PH PH12019501693A patent/PH12019501693A1/en unknown
- 2019-07-25 ZA ZA2019/04895A patent/ZA201904895B/en unknown
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