EA017985B1 - Способы определения устойчивости рака к ингибиторам гистондеацетилазы - Google Patents

Способы определения устойчивости рака к ингибиторам гистондеацетилазы Download PDF

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EA017985B1
EA017985B1 EA200900927A EA200900927A EA017985B1 EA 017985 B1 EA017985 B1 EA 017985B1 EA 200900927 A EA200900927 A EA 200900927A EA 200900927 A EA200900927 A EA 200900927A EA 017985 B1 EA017985 B1 EA 017985B1
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EA
Eurasian Patent Office
Prior art keywords
cancer
expression
biomarker genes
expression levels
inhibitor
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EA200900927A
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English (en)
Russian (ru)
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EA200900927A1 (ru
Inventor
Джозеф Дж. Багги
Срирам Баласубраманиан
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Фармасайкликс, Инк.
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Publication of EA200900927A1 publication Critical patent/EA200900927A1/ru
Publication of EA017985B1 publication Critical patent/EA017985B1/ru

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    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
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    • C12Q2537/143—Multiplexing, i.e. use of multiple primers or probes in a single reaction, usually for simultaneously analyse of multiple analysis
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    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
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    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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EA200900927A 2007-01-30 2008-01-30 Способы определения устойчивости рака к ингибиторам гистондеацетилазы EA017985B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88731807P 2007-01-30 2007-01-30
US91185507P 2007-04-13 2007-04-13
PCT/US2008/052540 WO2008095050A1 (en) 2007-01-30 2008-01-30 Methods for determining cancer resistance to histone deacetylase inhibitors

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EA200900927A1 EA200900927A1 (ru) 2010-04-30
EA017985B1 true EA017985B1 (ru) 2013-04-30

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EA200900927A EA017985B1 (ru) 2007-01-30 2008-01-30 Способы определения устойчивости рака к ингибиторам гистондеацетилазы
EA201201640A EA201201640A1 (ru) 2007-01-30 2008-01-30 Способы определения устойчивости рака к ингибиторам гистондеацетилазы

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US (3) US7838234B2 (enExample)
EP (2) EP2107911A4 (enExample)
JP (2) JP5670055B2 (enExample)
KR (1) KR101483805B1 (enExample)
CN (1) CN101657217B (enExample)
AU (2) AU2008210421B2 (enExample)
CA (1) CA2677000A1 (enExample)
EA (2) EA017985B1 (enExample)
NZ (1) NZ579048A (enExample)
WO (1) WO2008095050A1 (enExample)

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