EA017456B1 - Новые конструкты для экспрессии вируса гриппа - Google Patents
Новые конструкты для экспрессии вируса гриппа Download PDFInfo
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- EA017456B1 EA017456B1 EA201000076A EA201000076A EA017456B1 EA 017456 B1 EA017456 B1 EA 017456B1 EA 201000076 A EA201000076 A EA 201000076A EA 201000076 A EA201000076 A EA 201000076A EA 017456 B1 EA017456 B1 EA 017456B1
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- Prior art keywords
- viral
- linear expression
- rna
- promoter
- expression construct
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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| US94665107P | 2007-06-27 | 2007-06-27 | |
| EP07450177A EP2045323A1 (en) | 2007-10-05 | 2007-10-05 | Linear expression constructs for production of influenza virus particles |
| PCT/EP2008/058182 WO2009000891A2 (en) | 2007-06-27 | 2008-06-26 | Linear expression constructs for production of influenza virus particles |
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| EA201000076A1 EA201000076A1 (ru) | 2010-06-30 |
| EA017456B1 true EA017456B1 (ru) | 2012-12-28 |
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| CN (1) | CN101952427A (https=) |
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| CA (1) | CA2689569C (https=) |
| EA (1) | EA017456B1 (https=) |
| IN (1) | IN2009KN04355A (https=) |
| NZ (1) | NZ582102A (https=) |
| WO (1) | WO2009000891A2 (https=) |
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| US9091510B2 (en) | 2007-03-21 | 2015-07-28 | Schott Corporation | Transparent armor system and method of manufacture |
| EP2072058A1 (en) | 2007-12-21 | 2009-06-24 | Avir Green Hills Biotechnology Research Development Trade Ag | Modified influenza virus |
| EP2233568A1 (en) * | 2009-03-19 | 2010-09-29 | Avir Green Hills Biotechnology Research Development Trade AG | Novel method for generation of RNA virus |
| EP2573184A1 (en) | 2009-05-21 | 2013-03-27 | Novartis AG | Reverse genetics using non-endogenous POL I promoters |
| WO2011012999A1 (en) * | 2009-07-31 | 2011-02-03 | Novartis Ag | Reverse genetics systems |
| CN102741399A (zh) | 2009-10-20 | 2012-10-17 | 诺华有限公司 | 用于病毒拯救的改良反向遗传方法 |
| JP2013529913A (ja) | 2010-06-02 | 2013-07-25 | アヴィール グリーン ヒルズ バイオテクノロジー リサーチ ディベロプメント トレード アクチエンゲゼルシャフト | Ｒｎａウィルスの作製のための方法及びヘルパーウィルス |
| CN102495208B (zh) * | 2011-10-24 | 2014-03-26 | 山东省农业科学院畜牧兽医研究所 | 禽流感病毒rt-pcr elisa试剂盒 |
| US10206997B2 (en) * | 2011-11-10 | 2019-02-19 | Bin Wang | Facilitator-DNA combination vaccine |
| EP2820126B1 (en) | 2012-03-02 | 2017-05-17 | Seqirus UK Limited | Influenza virus reassortment |
| KR20150110494A (ko) | 2012-12-03 | 2015-10-02 | 노파르티스 아게 | 재배열 인플루엔자 a 바이러스 |
| HK1218511A1 (zh) | 2013-03-13 | 2017-02-24 | Novartis Ag | 乙型流感病毒重配 |
| DE202013005100U1 (de) | 2013-06-05 | 2013-08-26 | Novartis Ag | Influenza Virus Reassortierung |
| DE202013005130U1 (de) | 2013-06-05 | 2013-09-10 | Novartis Ag | Influenza Virus Reassortierung |
| CA2914604A1 (en) | 2013-06-06 | 2014-12-11 | Novartis Ag | Influenza virus reassortment |
| HK1254344A1 (zh) | 2015-06-26 | 2019-07-19 | Seqirus UK Limited | 抗原匹配的流感疫苗 |
| HUE051783T2 (hu) | 2015-07-07 | 2021-03-29 | Seqirus Uk Ltd | Eljárás immunogén hemagglutinin mennyiségi meghatározására |
| JP2023502650A (ja) | 2019-11-18 | 2023-01-25 | セキラス ピーティーワイ リミテッド | 遺伝子再集合インフルエンザウイルスを産生するための方法 |
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| WO2000060050A2 (en) * | 1999-04-06 | 2000-10-12 | Wisconsin Alumni Research Foundation | Recombinant influenza viruses for vaccines and gene therapy |
| WO2001004333A1 (en) * | 1999-07-14 | 2001-01-18 | Mount Sinai School Of Medicine Of New York University | In vitro reconstitution of segmented negative-strand rna viruses |
| WO2001083794A2 (en) * | 2000-04-28 | 2001-11-08 | St. Jude Children's Research Hospital | Dna transfection system for the generation of infectious influenza virus |
| WO2003091401A2 (en) * | 2002-04-26 | 2003-11-06 | Medimmune Vaccines, Inc. | Multi plasmid system for the production of influenza virus |
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| KR100637937B1 (ko) * | 1998-06-12 | 2006-10-23 | 마운트 시나이 스쿨 오브 메디신 오브 뉴욕 유니버시티 | 변형된 인터페론 길항물질을 보유하고, 백신 및 약제로사용되는 약독화된 네거티브 가닥 바이러스 |
| ATE384126T1 (de) * | 1998-06-12 | 2008-02-15 | Sinai School Medicine | Interferon induzierende genetisch veränderte attenuierte viren |
| EP3332803B1 (en) * | 2004-06-01 | 2021-09-08 | Icahn School of Medicine at Mount Sinai | Genetically engineered swine influenza virus and uses thereof |
| CN101103103A (zh) * | 2004-11-19 | 2008-01-09 | 威斯康星旧生研究基金会 | 具有串联转录单位的重组流感病毒载体 |
| WO2008156681A2 (en) * | 2007-06-14 | 2008-12-24 | Yoshihiro Kawaoka | Adenoviral vectors for influenza virus production |
-
2007
- 2007-10-05 EP EP07450177A patent/EP2045323A1/en not_active Withdrawn
-
2008
- 2008-06-26 WO PCT/EP2008/058182 patent/WO2009000891A2/en not_active Ceased
- 2008-06-26 EA EA201000076A patent/EA017456B1/ru not_active IP Right Cessation
- 2008-06-26 CN CN2008800223549A patent/CN101952427A/zh active Pending
- 2008-06-26 CA CA2689569A patent/CA2689569C/en active Active
- 2008-06-26 EP EP08774359.7A patent/EP2160462B1/en active Active
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- 2008-06-26 AU AU2008267180A patent/AU2008267180B2/en active Active
- 2008-06-26 US US12/666,459 patent/US20100129399A1/en not_active Abandoned
- 2008-06-26 IN IN4355KON2009 patent/IN2009KN04355A/en unknown
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| WO2000056914A1 (en) * | 1999-03-24 | 2000-09-28 | Gene Therapy Systems, Inc. | Method for generating transcriptionally active dna fragments |
| WO2000060050A2 (en) * | 1999-04-06 | 2000-10-12 | Wisconsin Alumni Research Foundation | Recombinant influenza viruses for vaccines and gene therapy |
| WO2001004333A1 (en) * | 1999-07-14 | 2001-01-18 | Mount Sinai School Of Medicine Of New York University | In vitro reconstitution of segmented negative-strand rna viruses |
| WO2001083794A2 (en) * | 2000-04-28 | 2001-11-08 | St. Jude Children's Research Hospital | Dna transfection system for the generation of infectious influenza virus |
| WO2003091401A2 (en) * | 2002-04-26 | 2003-11-06 | Medimmune Vaccines, Inc. | Multi plasmid system for the production of influenza virus |
| WO2005062820A2 (en) * | 2003-12-23 | 2005-07-14 | Medimmune Vaccines, Inc | Multi plasmid system for the production of influenza virus |
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Also Published As
| Publication number | Publication date |
|---|---|
| EA201000076A1 (ru) | 2010-06-30 |
| AU2008267180A1 (en) | 2008-12-31 |
| CA2689569A1 (en) | 2008-12-31 |
| CN101952427A (zh) | 2011-01-19 |
| IN2009KN04355A (https=) | 2015-07-10 |
| US20100129399A1 (en) | 2010-05-27 |
| AU2008267180B2 (en) | 2014-07-10 |
| CA2689569C (en) | 2020-10-27 |
| WO2009000891A3 (en) | 2009-02-26 |
| WO2009000891A2 (en) | 2008-12-31 |
| EP2160462B1 (en) | 2017-07-26 |
| EP2160462A2 (en) | 2010-03-10 |
| NZ582102A (en) | 2012-06-29 |
| EP2045323A1 (en) | 2009-04-08 |
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