EA016912B1 - Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения - Google Patents

Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения Download PDF

Info

Publication number
EA016912B1
EA016912B1 EA200901529A EA200901529A EA016912B1 EA 016912 B1 EA016912 B1 EA 016912B1 EA 200901529 A EA200901529 A EA 200901529A EA 200901529 A EA200901529 A EA 200901529A EA 016912 B1 EA016912 B1 EA 016912B1
Authority
EA
Eurasian Patent Office
Prior art keywords
alkyl
halogen
alkoxy
halo
alkylthio
Prior art date
Application number
EA200901529A
Other languages
English (en)
Russian (ru)
Other versions
EA200901529A1 (ru
Inventor
Марк Дейвид Солл
Лоик Патрик Лё Ир Де Фальуа
Скот Кевин Хубер
Хуонг Ик Ли
Дуглас Эдвард Уилкинсон
Роберт Томс Джэкобс
Original Assignee
Мериал Лимитед
Авентис Эгрикалчер
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Мериал Лимитед, Авентис Эгрикалчер filed Critical Мериал Лимитед
Publication of EA200901529A1 publication Critical patent/EA200901529A1/ru
Publication of EA016912B1 publication Critical patent/EA016912B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/34—Nitriles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having no bond to a nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics
    • A61P33/12—Schistosomicides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/42—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being further bound to other hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/16—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C07D249/18—Benzotriazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
EA200901529A 2007-05-15 2008-05-12 Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения EA016912B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93048507P 2007-05-15 2007-05-15
PCT/US2008/063417 WO2008144275A1 (en) 2007-05-15 2008-05-12 Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof

Publications (2)

Publication Number Publication Date
EA200901529A1 EA200901529A1 (ru) 2010-04-30
EA016912B1 true EA016912B1 (ru) 2012-08-30

Family

ID=38608776

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200901529A EA016912B1 (ru) 2007-05-15 2008-05-12 Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения

Country Status (31)

Country Link
US (2) US8088801B2 (enExample)
EP (4) EP2155699B9 (enExample)
JP (1) JP5562840B2 (enExample)
KR (3) KR101292600B1 (enExample)
CN (2) CN103483263B (enExample)
AR (1) AR066571A1 (enExample)
AU (1) AU2008254279B2 (enExample)
BR (2) BRPI0811635B1 (enExample)
CA (1) CA2684764C (enExample)
CL (1) CL2008001430A1 (enExample)
CY (3) CY1116858T1 (enExample)
DK (4) DK3428148T3 (enExample)
EA (1) EA016912B1 (enExample)
ES (4) ES2597083T3 (enExample)
HK (1) HK1258915A1 (enExample)
HR (4) HRP20151058T2 (enExample)
HU (4) HUE050538T2 (enExample)
LT (3) LT3088384T (enExample)
ME (1) ME03373B (enExample)
MX (1) MX2009012082A (enExample)
MY (1) MY154464A (enExample)
NZ (1) NZ580968A (enExample)
PL (4) PL2155699T3 (enExample)
PT (4) PT2155699E (enExample)
RS (4) RS60858B1 (enExample)
SG (3) SG169989A1 (enExample)
SI (4) SI3088384T1 (enExample)
TR (1) TR201903663T4 (enExample)
TW (1) TWI441633B (enExample)
UY (1) UY31093A1 (enExample)
WO (1) WO2008144275A1 (enExample)

Families Citing this family (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2222168B1 (en) * 2007-11-26 2018-09-12 Merial, Inc. Solvent systems for pour-on formulations for combating parasites
KR101782308B1 (ko) 2008-10-21 2017-09-27 메리얼 인코포레이티드 티오아미드 화합물, 이의 제조 방법 및 사용 방법
AR074024A1 (es) * 2008-11-14 2010-12-15 Merial Ltd Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria
KR101660068B1 (ko) 2008-11-19 2016-09-26 메리얼 인코포레이티드 기생충 감염 치료를 위한 1-아릴피라졸 단독 또는 포름아미딘과의 조합을 포함하는 조성물
TWI457347B (zh) 2008-12-04 2014-10-21 Merial Ltd 二聚合的阿佛菌素（ａｖｅｒｍｅｃｔｉｎ）及密倍脈心（ｍｉｌｂｅｍｙｃｉｎ）衍生物
DE102009012423A1 (de) * 2009-03-10 2010-09-16 Bayer Animal Health Gmbh Zubereitung auf Ölbasis
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
PH12018501647A1 (en) 2011-09-12 2019-02-27 Merial Inc Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof
WO2013057624A1 (en) 2011-10-19 2013-04-25 Ah Usa 42 Llc Use of aminoacetonitrile derivatives against endoparasites
CA2855954C (en) 2011-11-17 2020-09-01 Merial Limited Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof.
PL2785719T3 (pl) 2011-12-02 2018-03-30 Merial, Inc. Długodziałające wstrzykiwalne postaci moksydektyny i nowe postaci krystaliczne moksydektyny
SG11201404595TA (en) 2012-02-06 2014-09-26 Merial Ltd Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
BR112014024832B1 (pt) 2012-04-04 2022-05-31 Intervet International B.V. Método para a preparação de uma composição farmacêutica veterinária mastigável macia, composição farmacêutica, e, uso da composição
BR112014026184B1 (pt) 2012-04-20 2019-04-24 Merial, Inc. Composições parasiticídicas compreendendo derivados de benzimidazol, métodos e seus usos
EP3143994A1 (en) * 2012-08-30 2017-03-22 The University of Tokyo Endoparasite control agent and use thereof
US8822689B2 (en) * 2012-09-19 2014-09-02 Merial Limited Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
TWI631110B (zh) * 2013-03-14 2018-08-01 美商陶氏農業科學公司 具有一定殺蟲效用之分子，及與其相關之中間物、組成物暨方法
CN103267808A (zh) * 2013-04-22 2013-08-28 上海谱尼测试技术有限公司 一种电子电气产品中地乐酚含量的测定方法
SG11201603430XA (en) 2013-11-01 2016-05-30 Merial Ltd Antiparasitic and pesticidal isoxazoline compounds
ES2765405T3 (es) 2014-04-17 2020-06-09 Boehringer Ingelheim Animal Health Usa Inc Utilización de compuestos de malononitrilo para proteger animales de parásitos
US10045979B2 (en) 2014-05-19 2018-08-14 Merial Inc. Anthelmintic compounds
WO2015196014A1 (en) 2014-06-19 2015-12-23 Merial, Inc. Parasiticidal compositions comprising indole derivatives, methods and uses thereof
ES2887302T3 (es) 2014-10-31 2021-12-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
US10081656B2 (en) 2015-05-20 2018-09-25 Merial, Inc. Anthelmintic depsipeptide compounds
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
CN106106475A (zh) * 2016-06-22 2016-11-16 叶松 一种防治梨食芽蛾的组合物及其制备方法
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590B1 (en) 2016-10-14 2025-08-20 Boehringer Ingelheim Vetmedica GmbH Pesticidal and parasiticidal vinyl isoxazoline compounds
EP3541789A1 (en) 2016-11-16 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
CN106918705B (zh) * 2017-01-22 2023-06-13 贵州勤邦食品安全科学技术有限公司 检测甲氰菊酯的试纸及其应用
CN111194316A (zh) 2017-08-14 2020-05-22 勃林格殷格翰动物保健美国公司 农药的和杀寄生物的吡唑-异噁唑啉化合物
CN108033925A (zh) * 2017-12-27 2018-05-15 温州大学 一种苯并三氮唑化合物及其制备方法
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
IL279977B2 (en) 2018-07-09 2024-06-01 Boehringer Ingelheim Animal Health Usa Inc Heterocyclic anthelmintic compounds
CN108752217B (zh) * 2018-07-18 2021-08-06 浙江沙星科技有限公司 一种度鲁特韦关键中间体2,4-二氟苄胺的合成方法
CN113260419A (zh) * 2018-11-20 2021-08-13 勃林格殷格翰动物保健美国公司 吲唑基氰基乙基氨基化合物、其组合物、其制备方法和其使用方法
CN109694472B (zh) * 2018-12-13 2021-06-29 万华化学集团股份有限公司 功能性聚醚起始剂及其合成和在聚醚合成中的应用
US20220202835A1 (en) 2019-03-01 2022-06-30 Boehringer Ingelheim Animal Health USA Inc. Injectable clorsulon compositions, methods and uses thereof
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
CN110470768B (zh) * 2019-08-27 2022-05-24 谱尼测试集团吉林有限公司 一种测定水质中吡嘧磺隆、三唑磷、丁草胺残留量的方法
MX2022015038A (es) 2020-05-29 2023-01-04 Boehringer Ingelheim Animal Health Usa Inc Compuestos heterociclicos como anthelminticos.
WO2022140728A1 (en) 2020-12-21 2022-06-30 Boehringer Ingelheim Animam Health Usa Inc. Parasiticidal collar comprising isoxazoline compounds
WO2023156938A1 (en) 2022-02-17 2023-08-24 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer
CN115770411B (zh) * 2022-11-10 2025-07-25 上海市精神卫生中心（上海市心理咨询培训中心） 一种键合原卟啉的镁离子固相萃取剂及其应用
CN115888184A (zh) * 2022-11-10 2023-04-04 上海市精神卫生中心（上海市心理咨询培训中心） 一种用于血液镁离子检测的固相萃取装置及其应用
CN117143519B (zh) * 2023-05-05 2025-05-02 迪力阀门科技有限公司 一种耐高温蝶阀及其生产工艺

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003104202A1 (en) * 2002-06-07 2003-12-18 Novartis Ag Indazole-aminoacetonitrile derivatives having special pesticidal activity
WO2004024704A1 (en) * 2002-09-11 2004-03-25 Novartis Ag Organic compounds

Family Cites Families (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2753377B1 (fr) 1996-09-19 1999-09-24 Rhone Merieux Nouvelle association parasiticide a base de 1-n-phenylpyra- zoles et de lactones macrocycliques endectocides
US6426333B1 (en) 1996-09-19 2002-07-30 Merial Spot-on formulations for combating parasites
NL160809C (nl) 1970-05-15 1979-12-17 Duphar Int Res Werkwijze ter bereiding van benzoylureumverbindingen, alsmede werkwijze ter bereiding van insekticide prepara- ten op basis van benzoylureumverbindingen.
JPS4914624A (enExample) 1972-06-08 1974-02-08
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US3818047A (en) 1972-08-07 1974-06-18 C Henrick Substituted pyrones
SE434277B (sv) 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4166452A (en) 1976-05-03 1979-09-04 Generales Constantine D J Jr Apparatus for testing human responses to stimuli
CH604517A5 (enExample) 1976-08-19 1978-09-15 Ciba Geigy Ag
US4256108A (en) 1977-04-07 1981-03-17 Alza Corporation Microporous-semipermeable laminated osmotic system
US4134973A (en) 1977-04-11 1979-01-16 Merck & Co., Inc. Carbohydrate derivatives of milbemycin and processes therefor
US4199569A (en) 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
US4144352A (en) 1977-12-19 1979-03-13 Merck & Co., Inc. Milbemycin compounds as anthelmintic agents
US4203976A (en) 1978-08-02 1980-05-20 Merck & Co., Inc. Sugar derivatives of C-076 compounds
US4265874A (en) 1980-04-25 1981-05-05 Alza Corporation Method of delivering drug with aid of effervescent activity generated in environment of use
JPS57139012A (en) 1981-02-23 1982-08-27 Sankyo Co Ltd Anthelmintic composition
US4427663A (en) 1982-03-16 1984-01-24 Merck & Co., Inc. 4"-Keto-and 4"-amino-4"-deoxy avermectin compounds and substituted amino derivatives thereof
DE3235931A1 (de) 1982-09-29 1984-03-29 Bayer Ag, 5090 Leverkusen Koeder zur bekaempfung von ungeziefer
JPS59199673A (ja) 1983-04-25 1984-11-12 Sumitomo Chem Co Ltd 含窒素複素環化合物、その製造法およびそれを有効成分とする有害生物防除剤
EP0179022B1 (de) 1984-10-18 1990-11-07 Ciba-Geigy Ag Benzoylphenylharnstoffe
ATE67493T1 (de) 1985-02-04 1991-10-15 Bayer Agrochem Kk Heterocyclische verbindungen.
EP0237482A1 (de) 1986-03-06 1987-09-16 Ciba-Geigy Ag C(29)-Carbonyloxi-milbemycin-Derivate zur Bekämpfung von tier- und pflanzenparasitären Schädlingen
RU2024527C1 (ru) 1986-03-25 1994-12-15 Санкио Компани Лимитед Способ получения макролидных соединений
EP0252879B1 (de) 1986-07-02 1992-05-06 Ciba-Geigy Ag Pestizide
US4855317A (en) 1987-03-06 1989-08-08 Ciba-Geigy Corporation Insecticides and parasiticides
US4871719A (en) 1987-03-24 1989-10-03 Ciba-Geigy Corporation Composition for controlling parasites in productive livestock
US4874749A (en) 1987-07-31 1989-10-17 Merck & Co., Inc. 4"-Deoxy-4-N-methylamino avermectin Bla/Blb
DE3888936T2 (de) 1987-11-03 1994-07-21 Beecham Group Plc Zwischenprodukte für die Herstellung makrolider Antibiotika mit anthelmintischer Wirkung.
NZ232422A (en) 1989-02-16 1992-11-25 Merck & Co Inc 13-ketal milbemycin derivatives and parasiticides
NZ247278A (en) 1991-02-12 1995-03-28 Ancare Distributors Veterinary anthelmintic drench comprising a suspension of praziquantel in a liquid carrier
US5345377A (en) 1992-10-30 1994-09-06 Electric Power Research Institute, Inc. Harmonic controller for an active power line conditioner
GB9300883D0 (en) 1993-01-18 1993-03-10 Pfizer Ltd Antiparasitic agents
US5537529A (en) * 1993-04-22 1996-07-16 Apple Computer, Inc. Apparatus and method for creating versions of computer models and creating communications incorporating created versions therefrom
US5399582A (en) 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
US5806078A (en) * 1994-06-09 1998-09-08 Softool Corporation Version management system
AUPM969994A0 (en) 1994-11-28 1994-12-22 Virbac S.A. Equine anthelmintic formulations
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5962499A (en) 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
FR2739255B1 (fr) 1995-09-29 1998-09-04 Rhone Merieux Composition antiparasitaire pour le traitement et la protection des animaux de compagnie
US6366933B1 (en) * 1995-10-27 2002-04-02 At&T Corp. Method and apparatus for tracking and viewing changes on the web
US5885607A (en) 1996-03-29 1999-03-23 Rhone Merieux N-phenylpyrazole-based anti-flea and anti-tick external device for cats and dogs
US6010710A (en) 1996-03-29 2000-01-04 Merial Direct pour-on skin solution for antiparasitic use in cattle and sheep
FR2752525B1 (fr) 1996-08-20 2000-05-05 Rhone Merieux Procede de lutte contre les myiases des cheptels bovins et ovins et compositions pour la mise en oeuvre de ce procede
IE80657B1 (en) 1996-03-29 1998-11-04 Merial Sas Insecticidal combination to control mammal fleas in particular fleas on cats and dogs
US6366930B1 (en) * 1996-04-12 2002-04-02 Computer Associates Think, Inc. Intelligent data inventory & asset management systems method and apparatus
US6998131B2 (en) 1996-09-19 2006-02-14 Merial Limited Spot-on formulations for combating parasites
US6207647B1 (en) 1997-07-18 2001-03-27 Smithkline Beecham Corporation RatA
US5909689A (en) * 1997-09-18 1999-06-01 Sony Corporation Automatic update of file versions for files shared by several computers which record in respective file directories temporal information for indicating when the files have been created
US7062497B2 (en) * 1998-01-22 2006-06-13 Adobe Systems Incorporated Maintaining document state history
US6239077B1 (en) * 1998-05-01 2001-05-29 Nihon Nohyaku Co., Ltd. Aminoacetonitrile derivative agricultural and horticultural insecticide containing the same and use thereof
DE19823396A1 (de) 1998-05-26 1999-12-02 Bayer Ag Synergistische insektizide Mischungen
US6174540B1 (en) 1998-09-14 2001-01-16 Merck & Co., Inc. Long acting injectable formulations containing hydrogenated caster oil
EP1094411A1 (en) * 1999-10-20 2001-04-25 Sun Microsystems, Inc. Handling of different versions of a document
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
US6399786B1 (en) 2000-07-14 2002-06-04 Merck & Co., Inc. Nonacyclic nodulisporic acid derivatives
AU2002224942A1 (en) 2000-12-20 2002-07-01 Syngenta Participations Ag N-acyl aminoacetonitriles having pesticidal properties
WO2002049641A2 (en) * 2000-12-20 2002-06-27 Novartis Ag Anti-endoparasitic amidoacetonitrils
AR035531A1 (es) * 2001-01-22 2004-06-02 Novartis Ag Composicion para el control de plagas endoparasiticas en ganados y animales domesticos, un metodo para su control y el uso de dicha composicion para la preparacion de medicamentos
EP1390344B1 (en) * 2001-05-15 2006-12-27 Novartis AG Benzamidoacetonitrile derivatives and their use as antiparasitics
TWI236341B (en) * 2001-06-15 2005-07-21 Novartis Ag Aminoacetonitrile compounds for use in the control of endoparasites
EP1434760A2 (en) * 2001-10-04 2004-07-07 Novartis AG Carbonyloxy-cyanomethyl compounds as antiparasitic agents
JP2005504841A (ja) * 2001-10-04 2005-02-17 ノバルティス アクチエンゲゼルシャフト 有機化合物
TW200300140A (en) * 2001-11-14 2003-05-16 Novartis Ag Organic compounds
TWI261053B (en) * 2001-12-06 2006-09-01 Novartis Ag Amidoacetonitrile compounds, their preparation, compositions and use as pesticides
AR038156A1 (es) * 2002-01-21 2004-12-29 Novartis Ag Compuestos de amidoacetonitrilo, proceso para su preparacion, composicion para controlar los parasitos, y uso de estos compuestos para preparar una composicion farmaceutica
US7421660B2 (en) * 2003-02-04 2008-09-02 Cataphora, Inc. Method and apparatus to visually present discussions for data mining purposes
TW200305556A (en) 2002-03-21 2003-11-01 Novartis Ag Organic compounds
AR040082A1 (es) 2002-05-22 2005-03-16 Novartis Ag Derivados de n-acilaminoacetonitrilo y su uso para el control de parasitos
AR040229A1 (es) * 2002-05-22 2005-03-23 Novartis Ag Amidoacetonitrilos
AR039961A1 (es) * 2002-06-06 2005-03-09 Novartis Ag Derivados de amidoacetonitrilo y su uso como pesticida
TW200400932A (en) * 2002-06-19 2004-01-16 Novartis Ag Organic compounds
GB0214117D0 (en) * 2002-06-19 2002-07-31 Syngenta Participations Ag N-sulphonylaminoacetonitriles having pesticidal properties
US7001889B2 (en) 2002-06-21 2006-02-21 Merial Limited Anthelmintic oral homogeneous veterinary pastes
AU2004265101B2 (en) * 2003-08-14 2009-06-11 F. Hoffmann-La Roche Ag Gabanergic modulators
US8627489B2 (en) * 2003-10-31 2014-01-07 Adobe Systems Incorporated Distributed document version control
GB0402677D0 (en) * 2003-11-06 2004-03-10 Novartis Ag Organic compounds
AR046757A1 (es) * 2003-12-10 2005-12-21 Novartis Ag Amidoacetonitrilos utiles como pesticidas
EP1716511A1 (en) * 2004-02-20 2006-11-02 Dow Jones Reuters Business Interactive, LLC Intelligent search and retrieval system and method
AR049391A1 (es) 2004-06-10 2006-07-26 Novartis Ag Derivados de aminoacetonitrilo y su uso para controlar parasitos en animales de sangre caliente
US7702618B1 (en) * 2004-07-26 2010-04-20 Google Inc. Information retrieval system for archiving multiple document versions
WO2006043654A1 (ja) 2004-10-22 2006-04-27 Nihon Nohyaku Co., Ltd. アセトニトリル誘導体及び有害生物防除剤並びにその使用方法
DK1812385T3 (da) 2004-11-09 2012-10-15 Novartis Ag Fremgangsmåde til fremstilling af enantiomere af amidoacetonitrilforbindelser ud fra deres racemater
US7788237B2 (en) * 2004-12-17 2010-08-31 Microsoft Corporation Method and system for tracking changes in a document
US7593943B2 (en) * 2005-01-14 2009-09-22 Microsoft Corporation Method and system for synchronizing multiple user revisions to a shared object
EP1878249B1 (en) 2005-04-01 2020-03-04 LG Electronics, Inc. Method for scalably decoding a video signal
US20070057967A1 (en) * 2005-07-13 2007-03-15 Armstrong Orin R System and method for the display of versioned documents and amendments
AU2006278867A1 (en) * 2005-07-25 2007-02-15 Novartis Ag Amidonitrile compounds
US8316292B1 (en) * 2005-11-18 2012-11-20 Google Inc. Identifying multiple versions of documents
US20070150433A1 (en) * 2005-12-22 2007-06-28 Mediatek Inc. Method for managing file in version control system
US7809688B2 (en) * 2006-08-04 2010-10-05 Apple Inc. Managing backup of content
US8136292B2 (en) * 2009-11-13 2012-03-20 Wayne Steven Morgan Device and method for support of sheet material

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003104202A1 (en) * 2002-06-07 2003-12-18 Novartis Ag Indazole-aminoacetonitrile derivatives having special pesticidal activity
WO2004024704A1 (en) * 2002-09-11 2004-03-25 Novartis Ag Organic compounds

Also Published As

Publication number Publication date
TWI441633B (zh) 2014-06-21
AU2008254279B2 (en) 2013-03-14
LT3428148T (lt) 2020-10-12
HUE025612T2 (en) 2016-03-29
EP2155699A1 (en) 2010-02-24
CN101743230A (zh) 2010-06-16
DK3428148T3 (da) 2020-08-31
EP3088384A1 (en) 2016-11-02
SI3428148T1 (sl) 2021-04-30
AR066571A1 (es) 2009-08-26
US8283475B2 (en) 2012-10-09
PL2639228T3 (pl) 2017-01-31
CN103483263A (zh) 2014-01-01
EP3428148B1 (en) 2020-07-08
DK2155699T3 (en) 2015-07-20
KR20100022981A (ko) 2010-03-03
PT2639228T (pt) 2016-10-11
BRPI0811635A2 (pt) 2014-11-11
SI2639228T1 (sl) 2017-03-31
SI3088384T1 (sl) 2019-04-30
CY1121854T1 (el) 2020-07-31
CY1116858T1 (el) 2017-04-05
EP2639228B1 (en) 2016-07-13
HRP20151058T2 (hr) 2017-02-24
ES2825198T3 (es) 2021-05-14
CA2684764A1 (en) 2008-11-27
EA200901529A1 (ru) 2010-04-30
CL2008001430A1 (es) 2009-09-25
HRP20161240T1 (hr) 2016-12-02
HK1141026A1 (zh) 2010-10-29
DK3088384T3 (en) 2019-03-11
RS54332B1 (sr) 2016-02-29
KR101292600B1 (ko) 2013-08-05
MY154464A (en) 2015-06-30
PT2155699E (pt) 2015-11-12
PL3428148T3 (pl) 2020-12-28
KR101546639B1 (ko) 2015-08-21
RS55271B1 (sr) 2017-02-28
HK1258915A1 (zh) 2019-11-22
ES2714578T3 (es) 2019-05-29
WO2008144275A1 (en) 2008-11-27
HUE050538T2 (hu) 2020-12-28
EP2639228A3 (en) 2013-09-25
JP2010527368A (ja) 2010-08-12
HRP20190408T1 (hr) 2019-04-19
EP2155699B9 (en) 2016-09-14
HRP20151058T1 (xx) 2015-12-04
PT3088384T (pt) 2019-03-22
NZ580968A (en) 2012-03-30
ES2597083T3 (es) 2017-01-13
PL2155699T3 (pl) 2016-03-31
CN103483263B (zh) 2016-04-13
SI2155699T1 (sl) 2015-12-31
LT2639228T (lt) 2016-11-10
TW200848023A (en) 2008-12-16
SG10201601056XA (en) 2016-04-28
SG148142A1 (en) 2008-12-31
HUE029127T2 (en) 2017-02-28
AU2008254279A1 (en) 2008-11-27
HUE042633T2 (hu) 2019-07-29
BR122018010599B1 (pt) 2019-05-14
PT3428148T (pt) 2020-10-13
JP5562840B2 (ja) 2014-07-30
LT3088384T (lt) 2019-05-27
KR20120120994A (ko) 2012-11-02
EP2639228A2 (en) 2013-09-18
ME03373B (me) 2020-01-20
DK2639228T3 (en) 2016-09-12
TR201903663T4 (tr) 2019-04-22
RS58416B1 (sr) 2019-04-30
DK2155699T5 (en) 2017-05-22
US20120149750A1 (en) 2012-06-14
KR20140107698A (ko) 2014-09-04
KR101472649B1 (ko) 2014-12-16
ES2549377T3 (es) 2015-10-27
CY1118346T1 (el) 2017-06-28
US20080312272A1 (en) 2008-12-18
CA2684764C (en) 2013-03-19
EP2155699B1 (en) 2015-07-08
SG169989A1 (en) 2011-04-29
RS54332B9 (sr) 2019-10-31
UY31093A1 (es) 2009-04-30
PL3088384T3 (pl) 2019-06-28
EP3428148A1 (en) 2019-01-16
HRP20201340T1 (hr) 2021-02-05
MX2009012082A (es) 2009-12-01
BRPI0811635B1 (pt) 2018-11-06
HK1185609A1 (en) 2014-02-21
US8088801B2 (en) 2012-01-03
RS60858B1 (sr) 2020-10-30
EP3088384B1 (en) 2018-12-12
CN101743230B (zh) 2013-06-05

Similar Documents

Publication Publication Date Title
EA016912B1 (ru) Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения
JP6010846B2 (ja) エナンチオマー的に富化されたアリーロアゾール−２−イル−シアノエチルアミノ殺寄生生物性化合物
EA026649B1 (ru) Тиоамидные соединения, способ их получения и способ их применения
US8822689B2 (en) Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
AU2013205750B2 (en) Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
HK1225011B (en) Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof
HK1141026B (en) Aryloazol-2-yl cyanoethylamino compounds, method of making and method of using thereof

Legal Events

Date Code Title Description
PC4A Registration of transfer of a eurasian patent by assignment
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU