EA015907B1 - Рекомбинантный флавивирус и его применение - Google Patents
Рекомбинантный флавивирус и его применение Download PDFInfo
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- EA015907B1 EA015907B1 EA200700904A EA200700904A EA015907B1 EA 015907 B1 EA015907 B1 EA 015907B1 EA 200700904 A EA200700904 A EA 200700904A EA 200700904 A EA200700904 A EA 200700904A EA 015907 B1 EA015907 B1 EA 015907B1
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- Prior art keywords
- flavivirus
- virus
- mutation
- protein
- mutations
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- C12N2770/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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| PCT/US2005/037369 WO2006044857A2 (en) | 2004-10-20 | 2005-10-19 | Vaccines against japanese encephalitis virus and west nile virus |
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Cited By (1)
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| WO2014210358A1 (en) * | 2013-06-26 | 2014-12-31 | The University Of North Carolina At Chapel Hill | Methods and compositions for dengue virus vaccines |
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| PL371187A1 (en) | 2001-06-01 | 2005-06-13 | Acambis, Inc. | Chimeric flavivirus vectors |
| AU2003267937C1 (en) | 2002-01-15 | 2019-08-08 | Sanofi Pasteur Biologics, Llc | Flavivirus vaccines |
| JP4683926B2 (ja) | 2002-11-15 | 2011-05-18 | サノフィ パスツール バイオロジクス カンパニー | ウエストナイルウイルス・ワクチン |
| US8029802B2 (en) | 2004-10-20 | 2011-10-04 | Sanofi Pasteur Biologics Co. | Vaccines against Japanese encephalitis virus and West Nile virus |
| AU2013204985B2 (en) * | 2005-04-24 | 2016-01-28 | Sanofi Pasteur Biologics, Llc | Recombinant flavivirus vaccines |
| BRPI0609949A2 (pt) | 2005-04-24 | 2010-05-11 | Acambis Inc | flavivìrus recombinante, seu uso na preparação de vacina, composição farmacêutica compreendendo o mesmo, molécula de ácido nucléico e método para atenuar candidato a vacina de flavivìrus |
| AU2007303608B2 (en) | 2006-09-29 | 2013-05-02 | Takeda Vaccines, Inc. | Norovirus vaccine formulations |
| EP2086581B1 (en) | 2006-11-07 | 2014-08-13 | Sanofi Pasteur Biologics, LLC | Stabilization of vaccines by lyophilization |
| WO2008115314A2 (en) * | 2007-01-31 | 2008-09-25 | Sanofi Pasteur Biologics Co. | Flavivirus vaccine vector against influenza virus |
| US10130696B2 (en) | 2007-09-18 | 2018-11-20 | Takeda Vaccines, Inc. | Method of conferring a protective immune response to norovirus |
| US20100266636A1 (en) | 2007-09-18 | 2010-10-21 | Ligocyte Pharmaceuticals, Inc. | Method of conferring a protective immune response to norovirus |
| AU2009241354B2 (en) * | 2008-04-30 | 2014-06-12 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Chimeric West Nile/Dengue viruses |
| SG2013057732A (en) | 2008-08-08 | 2015-02-27 | Ligocyte Pharmaceuticals Inc | Virus-like particles comprising composite capsid amino acid sequences for enhanced cross reactivity |
| CA3001374A1 (en) * | 2008-11-17 | 2010-05-20 | Vgx Pharmaceuticals, Llc | Antigens that elicit immune response against flavivirus and methods of using same |
| US8968996B2 (en) | 2009-06-01 | 2015-03-03 | Takeda Vaccines, Inc. | Compositions and methods for rapid immunization against dengue virus |
| MX343172B (es) | 2009-06-01 | 2016-10-26 | Takeda Vaccines Inc | Composiciones y metodos para administracion de vacunas contra virus del dengue. |
| CA3150404A1 (en) | 2009-07-31 | 2011-02-03 | Pnuvax Inc. | High yield yellow fever virus strain with increased propagation in cells |
| US10081795B2 (en) * | 2010-03-24 | 2018-09-25 | Research Development Foundation | Flavivirus host range mutations and uses thereof |
| CN101926989A (zh) * | 2010-06-29 | 2010-12-29 | 西北农林科技大学 | 表达jev免疫原基因的重组减毒鼠伤寒沙门氏菌载体疫苗及其制备方法 |
| WO2012003320A2 (en) * | 2010-07-01 | 2012-01-05 | Research Development Foundation | Flavivirus host-range mutations and uses thereof |
| EA202090699A3 (ru) | 2011-07-11 | 2020-11-30 | Такеда Вэксинс, Инк. | Композиции, содержащие буфер, вакцины, которые содержат композиции, содержащие буфер, и пути их применения |
| US9267114B2 (en) * | 2012-11-07 | 2016-02-23 | Southern Research Institute | Flavivirus envelope protein mutations affecting virion disassembly |
| US9878031B2 (en) | 2012-12-14 | 2018-01-30 | Takeda Vaccines, Inc. | Compositions, methods of administration and uses for trivalent dengue virus formulations |
| JP2016523251A (ja) | 2013-06-21 | 2016-08-08 | メルク・シャープ・アンド・ドーム・コーポレーションＭｅｒｃｋ Ｓｈａｒｐ ＆ Ｄｏｈｍｅ Ｃｏｒｐ． | デングウイルスワクチン組成物およびその使用方法 |
| WO2016079560A1 (en) | 2014-11-21 | 2016-05-26 | Institut Pasteur | A live and attenuated japanese encephalitis virus comprising a mutated m protein |
| AU2015369875A1 (en) | 2014-12-22 | 2017-06-15 | Merck Sharp & Dohme Corp. | Dengue virus vaccine compositions and methods of use thereof |
| EA035921B1 (ru) * | 2015-07-16 | 2020-08-31 | Бхарат Байотек Интернэшнл Лимитед | Вакцинные композиции для профилактики арбовирусных инфекций |
| WO2020194063A1 (en) * | 2019-03-28 | 2020-10-01 | Institut Pasteur | A live and attenuated flavivirus comprising a mutated m protein |
| WO2024254552A1 (en) * | 2023-06-08 | 2024-12-12 | Modernatx, Inc. | Stabilized flavivirus vaccines |
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| US5173418A (en) | 1985-05-10 | 1992-12-22 | Benzon Pharma, A/S | Production in Escherichia coli of extracellular Serratia spp. hydrolases |
| US6676936B1 (en) | 1988-07-14 | 2004-01-13 | The United States Of America As Represented By The Department Of Health And Human Services. | Chimeric and/or growth-restricted flaviviruses |
| US6184024B1 (en) | 1988-07-14 | 2001-02-06 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric and/or growth-restricted flaviviruses |
| US6962708B1 (en) | 1997-02-28 | 2005-11-08 | Acambis, Inc. | Chimeric flavivirus vaccines |
| NZ337522A (en) * | 1997-02-28 | 2001-02-23 | St | Chimeric flavivirus incorporating yellow fever virus modified such that a prM-E protein of a second flavivirus is expressed, and vaccines for flavivruses |
| US6589533B1 (en) | 1997-09-18 | 2003-07-08 | Research Development Foundation | Genetically-engineered alphaviruses, flaviviruses, and bunyaviruses with modified envelope transmembrane glycoproteins and altered host-range phenotype |
| AU9794198A (en) | 1997-10-08 | 1999-04-27 | Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The | Chimeric vaccine against tick-borne encephalitis virus |
| US7227011B2 (en) * | 1998-06-04 | 2007-06-05 | United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention | Nucleic acid vaccines for prevention of flavivirus infection |
| WO2001039802A1 (en) | 1999-12-01 | 2001-06-07 | Oravax, Inc. | Chimeric flavivirus vaccines |
| WO2002081753A1 (en) | 2001-04-04 | 2002-10-17 | Advanced Research & Technology Institute | Method for identifying and characterizing individual dna molecules |
| WO2003060088A2 (en) | 2002-01-15 | 2003-07-24 | Acambis, Inc. | Viral vaccine production method |
| US20050002968A1 (en) | 2002-01-15 | 2005-01-06 | Monath Thomas P. | Flavivirus vaccines |
| AU2003267937C1 (en) * | 2002-01-15 | 2019-08-08 | Sanofi Pasteur Biologics, Llc | Flavivirus vaccines |
| JP4683926B2 (ja) * | 2002-11-15 | 2011-05-18 | サノフィ パスツール バイオロジクス カンパニー | ウエストナイルウイルス・ワクチン |
| US7189403B2 (en) * | 2003-06-30 | 2007-03-13 | Institut Pasteur | Attenuated flavivirus strains containing a mutated M-ectodomain and their applications |
| US8029802B2 (en) | 2004-10-20 | 2011-10-04 | Sanofi Pasteur Biologics Co. | Vaccines against Japanese encephalitis virus and West Nile virus |
| BRPI0609949A2 (pt) | 2005-04-24 | 2010-05-11 | Acambis Inc | flavivìrus recombinante, seu uso na preparação de vacina, composição farmacêutica compreendendo o mesmo, molécula de ácido nucléico e método para atenuar candidato a vacina de flavivìrus |
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| MONATH, T.P. Recombinant, chimeric live, attenuated vaccine (ChimeriVaxTM) incorporating the envelope genes of Japanese encephalitis (SA14-14-2) virus and the capsid and nonstructural genes of yellow fever (17D) virus is safe, immunogenic and protective in non-human primates, Vaccine, 1999, Vol. 17, pages 1869-1882 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014210358A1 (en) * | 2013-06-26 | 2014-12-31 | The University Of North Carolina At Chapel Hill | Methods and compositions for dengue virus vaccines |
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| MY148075A (en) | 2013-02-28 |
| WO2006044857A3 (en) | 2006-08-10 |
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| KR20070072597A (ko) | 2007-07-04 |
| WO2006044857A2 (en) | 2006-04-27 |
| NZ584079A (en) | 2011-10-28 |
| SG156666A1 (en) | 2009-11-26 |
| JP2008520187A (ja) | 2008-06-19 |
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