EA011635B1 - Новые производные амида гетероциклической карбоновой кислоты - Google Patents
Новые производные амида гетероциклической карбоновой кислоты Download PDFInfo
- Publication number
- EA011635B1 EA011635B1 EA200700360A EA200700360A EA011635B1 EA 011635 B1 EA011635 B1 EA 011635B1 EA 200700360 A EA200700360 A EA 200700360A EA 200700360 A EA200700360 A EA 200700360A EA 011635 B1 EA011635 B1 EA 011635B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- formula
- values
- carboxylic acid
- hydroxy
- correspond
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Addiction (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Virology (AREA)
- Psychology (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- AIDS & HIV (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0401527A HU227119B1 (en) | 2004-07-29 | 2004-07-29 | Indole and benzimidazole carboxylic acid amide derivatives and pharmaceutical compositions containing them |
| PCT/HU2005/000082 WO2006010969A1 (en) | 2004-07-29 | 2005-07-21 | New heterocyclic carboxylic acid amide derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200700360A1 EA200700360A1 (ru) | 2007-06-29 |
| EA011635B1 true EA011635B1 (ru) | 2009-04-28 |
Family
ID=89985412
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200700360A EA011635B1 (ru) | 2004-07-29 | 2005-07-21 | Новые производные амида гетероциклической карбоновой кислоты |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US20080300276A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1771437A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2008508251A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20070038503A (cg-RX-API-DMAC7.html) |
| CN (1) | CN1989126A (cg-RX-API-DMAC7.html) |
| AP (1) | AP2076A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2005266164A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0513900A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2574169A1 (cg-RX-API-DMAC7.html) |
| EA (1) | EA011635B1 (cg-RX-API-DMAC7.html) |
| GE (1) | GEP20084494B (cg-RX-API-DMAC7.html) |
| HU (1) | HU227119B1 (cg-RX-API-DMAC7.html) |
| IL (1) | IL179483A0 (cg-RX-API-DMAC7.html) |
| MA (1) | MA28818B1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2007001049A (cg-RX-API-DMAC7.html) |
| NO (1) | NO20071112L (cg-RX-API-DMAC7.html) |
| TN (1) | TNSN07014A1 (cg-RX-API-DMAC7.html) |
| UA (1) | UA88643C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2006010969A1 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200700329B (cg-RX-API-DMAC7.html) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7935706B2 (en) | 2006-02-23 | 2011-05-03 | Shionogi & Co., Ltd. | Nitrogen-containing heterocycle derivatives substituted with cyclic group |
| JP2013519722A (ja) | 2010-02-16 | 2013-05-30 | ファイザー・インク | （ｒ）−４−（（４−（（４−（テトラヒドロフラン−３−イルオキシ）ベンゾ［ｄ］イソオキサゾール−３−イルオキシ）メチル）ピペリジン−１−イル）メチル）テトラヒドロ−２ｈ−ピラン−４−オール、５−ｈｔ４受容体の部分アゴニスト |
| CA2958966C (en) | 2014-08-28 | 2020-01-14 | Asceneuron Sa | Substituted cyclic amines as glucosidase inhibitors |
| DK3389658T3 (da) | 2015-12-18 | 2021-01-11 | Merck Sharp & Dohme | Glycosidasehæmmere og anvendelser deraf |
| WO2017144633A1 (en) | 2016-02-25 | 2017-08-31 | Asceneuron S. A. | Glycosidase inhibitors |
| WO2017144637A1 (en) | 2016-02-25 | 2017-08-31 | Asceneuron S. A. | Acid addition salts of piperazine derivatives |
| CA3012624A1 (en) | 2016-02-25 | 2017-08-31 | Asceneuron S.A. | Glycosidase inhibitors |
| US11261183B2 (en) | 2016-02-25 | 2022-03-01 | Asceneuron Sa | Sulfoximine glycosidase inhibitors |
| EP3672959A1 (en) | 2017-08-24 | 2020-07-01 | Asceneuron SA | Linear glycosidase inhibitors |
| WO2020039029A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Spiro compounds as glycosidase inhibitors |
| WO2020039027A1 (en) | 2018-08-22 | 2020-02-27 | Asceneuron S. A. | Pyrrolidine glycosidase inhibitors |
| US11795165B2 (en) | 2018-08-22 | 2023-10-24 | Asceneuron Sa | Tetrahydro-benzoazepine glycosidase inhibitors |
| MX2021002111A (es) | 2018-08-22 | 2021-07-16 | Asceneuron S A | Sales de adición de ácido de succinato y fumarato de derivados de piperazina útiles como inhibidores de glucosidasa. |
| EP3980420B1 (en) | 2019-06-04 | 2023-04-19 | Boehringer Ingelheim International GmbH | Imidazopyrazine derivatives and the use thereof as medicament |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002034718A1 (en) * | 2000-10-24 | 2002-05-02 | Richter Gedeon Vegyeszeti Gyar Rt. | Amide derivatives as nmda receptor antagonists |
-
2004
- 2004-07-29 HU HU0401527A patent/HU227119B1/hu unknown
-
2005
- 2005-07-21 KR KR1020077000266A patent/KR20070038503A/ko not_active Withdrawn
- 2005-07-21 AP AP2006003843A patent/AP2076A/en active
- 2005-07-21 WO PCT/HU2005/000082 patent/WO2006010969A1/en not_active Ceased
- 2005-07-21 EA EA200700360A patent/EA011635B1/ru not_active IP Right Cessation
- 2005-07-21 CA CA002574169A patent/CA2574169A1/en not_active Abandoned
- 2005-07-21 AU AU2005266164A patent/AU2005266164A1/en not_active Abandoned
- 2005-07-21 JP JP2007523164A patent/JP2008508251A/ja not_active Withdrawn
- 2005-07-21 MX MX2007001049A patent/MX2007001049A/es not_active Application Discontinuation
- 2005-07-21 GE GEAP20059896A patent/GEP20084494B/en unknown
- 2005-07-21 CN CNA2005800241844A patent/CN1989126A/zh active Pending
- 2005-07-21 US US11/658,486 patent/US20080300276A1/en not_active Abandoned
- 2005-07-21 EP EP05764183A patent/EP1771437A1/en not_active Withdrawn
- 2005-07-21 UA UAA200702172A patent/UA88643C2/ru unknown
- 2005-07-21 BR BRPI0513900-7A patent/BRPI0513900A/pt not_active IP Right Cessation
-
2006
- 2006-11-22 IL IL179483A patent/IL179483A0/en unknown
-
2007
- 2007-01-11 ZA ZA200700329A patent/ZA200700329B/en unknown
- 2007-01-17 TN TNP2007000014A patent/TNSN07014A1/en unknown
- 2007-02-22 MA MA29705A patent/MA28818B1/fr unknown
- 2007-02-27 NO NO20071112A patent/NO20071112L/no not_active Application Discontinuation
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002034718A1 (en) * | 2000-10-24 | 2002-05-02 | Richter Gedeon Vegyeszeti Gyar Rt. | Amide derivatives as nmda receptor antagonists |
Non-Patent Citations (2)
| Title |
|---|
| BARTA-SZALAI, GISELA ET AL.: "Oxamides as novel NR2B selective NMDA receptor antagonists", BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 14, 2004, pages 3953-3956, XP002349702, compound 1 * |
| ISTVAN BORZA ET AL.: "Indole-2-carboxamides as novel NR2B selective NMDA Receptor antagonists", BIOORGANIC AND MEDICINAL CHEMISTRY LETTERS, vol. 13, 2003, pages 3859-3861, XP002349801, table 1; compound 2 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2574169A1 (en) | 2006-02-02 |
| AP2006003843A0 (en) | 2006-12-31 |
| HU0401527D0 (en) | 2004-09-28 |
| AP2076A (en) | 2009-12-17 |
| BRPI0513900A (pt) | 2008-05-20 |
| KR20070038503A (ko) | 2007-04-10 |
| MA28818B1 (fr) | 2007-08-01 |
| IL179483A0 (en) | 2007-05-15 |
| AU2005266164A1 (en) | 2006-02-02 |
| MX2007001049A (es) | 2007-04-16 |
| EA200700360A1 (ru) | 2007-06-29 |
| WO2006010969A1 (en) | 2006-02-02 |
| EP1771437A1 (en) | 2007-04-11 |
| HUP0401527A3 (en) | 2008-04-28 |
| WO2006010969A8 (en) | 2006-08-31 |
| CN1989126A (zh) | 2007-06-27 |
| US20080300276A1 (en) | 2008-12-04 |
| NO20071112L (no) | 2007-02-27 |
| JP2008508251A (ja) | 2008-03-21 |
| HUP0401527A2 (en) | 2006-01-30 |
| ZA200700329B (en) | 2008-05-28 |
| UA88643C2 (ru) | 2009-11-10 |
| GEP20084494B (en) | 2008-09-25 |
| HU227119B1 (en) | 2010-07-28 |
| TNSN07014A1 (en) | 2008-06-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP4225779B2 (ja) | Ｎｍｄａ受容体拮抗剤としてのアミド誘導体 | |
| RU2351588C2 (ru) | Производные n-фенил(пиперидин-2-ил)метил-бензамида и их применение в терапии | |
| EA010162B1 (ru) | Амидные производные карбоновых кислот | |
| EA011241B1 (ru) | Новые производные 4-бензилиденпиперидина | |
| ZA200700329B (en) | New heterocyclic carboxylic acid amide derivatives | |
| JP4610480B2 (ja) | ２，６−ジ置換スチリルを有する含窒素ヘテロ環誘導体 | |
| JP3064425B2 (ja) | カルシウムチャンネル・ブロッカーとしてのピペリジン化合物 | |
| DE60112725T2 (de) | Phenoxyalkylaminderivate als agonisten des opioid-delta rezeptors | |
| DE69529790T2 (de) | Imidazolin-Derivate, deren Herstellung und deren Verwendung als Tachykinin-Rezeptor Antagonisten | |
| EA011636B1 (ru) | Производные амида кинуреновой кислоты как антагонисты nr2b подтипа рецептора nmda | |
| JPH02152963A (ja) | ４―フェニル―４―〔ｎ―（フェニル）アミド〕ピペリジン誘導体及びこの誘導体を含む製剤組成物 | |
| EA010893B1 (ru) | Новые производные бензоилмочевины | |
| WO2006025471A1 (ja) | ピペリジン誘導体又はその製薬学的に許容される塩 | |
| HK1105966B (en) | New 4-benzylidene-piperidin derivatives |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |