EA006608B1 - Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов - Google Patents
Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов Download PDFInfo
- Publication number
- EA006608B1 EA006608B1 EA200301167A EA200301167A EA006608B1 EA 006608 B1 EA006608 B1 EA 006608B1 EA 200301167 A EA200301167 A EA 200301167A EA 200301167 A EA200301167 A EA 200301167A EA 006608 B1 EA006608 B1 EA 006608B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- alkyl
- halogen
- different meanings
- group
- halogen atoms
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10123952A DE10123952A1 (de) | 2001-05-17 | 2001-05-17 | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
| PCT/EP2002/005338 WO2002100411A1 (en) | 2001-05-17 | 2002-05-15 | Naphtothiazine positive allosteric ampa receptor modulators (paarm) |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200301167A1 EA200301167A1 (ru) | 2004-06-24 |
| EA006608B1 true EA006608B1 (ru) | 2006-02-24 |
Family
ID=7685080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200301167A EA006608B1 (ru) | 2001-05-17 | 2002-05-15 | Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов |
Country Status (26)
| Country | Link |
|---|---|
| EP (1) | EP1404340A1 (pt) |
| JP (1) | JP2004529980A (pt) |
| KR (1) | KR20040007572A (pt) |
| CN (1) | CN1533278A (pt) |
| AR (1) | AR036332A1 (pt) |
| BG (1) | BG108324A (pt) |
| BR (1) | BR0209796A (pt) |
| CA (1) | CA2449189A1 (pt) |
| CO (1) | CO5550460A2 (pt) |
| CZ (1) | CZ20033112A3 (pt) |
| DE (1) | DE10123952A1 (pt) |
| EA (1) | EA006608B1 (pt) |
| EC (1) | ECSP034852A (pt) |
| EE (1) | EE200300566A (pt) |
| HR (1) | HRP20030933A2 (pt) |
| HU (1) | HUP0401273A3 (pt) |
| IL (1) | IL158642A0 (pt) |
| MX (1) | MXPA03010373A (pt) |
| NO (1) | NO20035088L (pt) |
| NZ (1) | NZ530154A (pt) |
| PL (1) | PL364053A1 (pt) |
| SK (1) | SK14222003A3 (pt) |
| UY (1) | UY27290A1 (pt) |
| WO (1) | WO2002100411A1 (pt) |
| YU (1) | YU90403A (pt) |
| ZA (1) | ZA200308466B (pt) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20090047534A (ko) * | 2006-08-31 | 2009-05-12 | 더 거버너스 오브 더 유니버시티 오브 앨버타 | 양성 알로스테릭 ａｍｐａ 수용체 조절인자를 사용하여 호흡 저하를 억제하는 방법 |
| CN111518058B (zh) * | 2020-05-29 | 2021-03-09 | 四川大学华西医院 | 一种噁噻嗪类化合物及其用途 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4345297A (en) * | 1996-09-17 | 1998-04-14 | Regents Of The University Of California, The | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
| JP2002518498A (ja) * | 1998-06-25 | 2002-06-25 | メルク エンド カムパニー インコーポレーテッド | ナフト［１，８−ｄｅ］チアジン−２−イルメチルカルバペネム抗菌物質 |
| DE10004572A1 (de) * | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | Neue positive allosterische AMPA-Rezeptor Modulatoren (PAARM), Verfahren zu deren Herstellung und deren Verwendung als Arzneimittel |
-
2001
- 2001-05-17 DE DE10123952A patent/DE10123952A1/de not_active Withdrawn
-
2002
- 2002-05-15 BR BR0209796-6A patent/BR0209796A/pt not_active Expired - Fee Related
- 2002-05-15 IL IL15864202A patent/IL158642A0/xx unknown
- 2002-05-15 MX MXPA03010373A patent/MXPA03010373A/es unknown
- 2002-05-15 HU HU0401273A patent/HUP0401273A3/hu unknown
- 2002-05-15 EE EEP200300566A patent/EE200300566A/xx unknown
- 2002-05-15 PL PL02364053A patent/PL364053A1/xx not_active Application Discontinuation
- 2002-05-15 YU YU90403A patent/YU90403A/sh unknown
- 2002-05-15 EA EA200301167A patent/EA006608B1/ru not_active IP Right Cessation
- 2002-05-15 CZ CZ20033112A patent/CZ20033112A3/cs unknown
- 2002-05-15 CA CA002449189A patent/CA2449189A1/en not_active Abandoned
- 2002-05-15 EP EP02750931A patent/EP1404340A1/en not_active Withdrawn
- 2002-05-15 CN CNA028100832A patent/CN1533278A/zh active Pending
- 2002-05-15 JP JP2003503232A patent/JP2004529980A/ja not_active Abandoned
- 2002-05-15 KR KR10-2003-7014965A patent/KR20040007572A/ko not_active Application Discontinuation
- 2002-05-15 NZ NZ530154A patent/NZ530154A/en unknown
- 2002-05-15 WO PCT/EP2002/005338 patent/WO2002100411A1/en not_active Application Discontinuation
- 2002-05-15 SK SK1422-2003A patent/SK14222003A3/sk unknown
- 2002-05-15 UY UY27290A patent/UY27290A1/es not_active Application Discontinuation
- 2002-05-17 AR ARP020101827A patent/AR036332A1/es not_active Suspension/Interruption
-
2003
- 2003-10-30 ZA ZA200308466A patent/ZA200308466B/en unknown
- 2003-11-07 BG BG108324A patent/BG108324A/bg active Pending
- 2003-11-14 HR HR20030933A patent/HRP20030933A2/xx not_active Application Discontinuation
- 2003-11-14 NO NO20035088A patent/NO20035088L/no not_active Application Discontinuation
- 2003-11-17 EC EC2003004852A patent/ECSP034852A/es unknown
- 2003-12-01 CO CO03105591A patent/CO5550460A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN1533278A (zh) | 2004-09-29 |
| SK14222003A3 (sk) | 2004-05-04 |
| AR036332A1 (es) | 2004-09-01 |
| NZ530154A (en) | 2005-09-30 |
| ZA200308466B (en) | 2004-05-24 |
| MXPA03010373A (es) | 2004-03-16 |
| CZ20033112A3 (en) | 2004-03-17 |
| CO5550460A2 (es) | 2005-08-31 |
| BG108324A (bg) | 2004-12-30 |
| HUP0401273A2 (hu) | 2004-10-28 |
| IL158642A0 (en) | 2004-05-12 |
| CA2449189A1 (en) | 2002-12-19 |
| KR20040007572A (ko) | 2004-01-24 |
| HRP20030933A2 (en) | 2004-04-30 |
| ECSP034852A (es) | 2003-12-24 |
| PL364053A1 (en) | 2004-12-13 |
| JP2004529980A (ja) | 2004-09-30 |
| NO20035088D0 (no) | 2003-11-14 |
| NO20035088L (no) | 2003-11-14 |
| UY27290A1 (es) | 2002-12-31 |
| EA200301167A1 (ru) | 2004-06-24 |
| BR0209796A (pt) | 2004-06-01 |
| EP1404340A1 (en) | 2004-04-07 |
| DE10123952A1 (de) | 2002-11-21 |
| EE200300566A (et) | 2004-02-16 |
| WO2002100411A1 (en) | 2002-12-19 |
| HUP0401273A3 (en) | 2006-11-28 |
| YU90403A (sh) | 2006-05-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CA2683557C (en) | Inhibitors of histone deacetylase | |
| CA2409743C (en) | Substituted pyrrolopyridinone derivatives useful as phosphodiesterase inhibitors | |
| US6350749B1 (en) | Aminoguanidine hydrazone derivatives, process for producing the same and drugs thereof | |
| DK173297B1 (da) | Perhydrothiazepinderivater, fremgangsmåde til fremstilling deraf samt farmaceutisk præparat til behandling af hypertension | |
| AU2004255191A1 (en) | Phenylcarboxylate beta-secretase inhibitors for the treatment of Alzheimer's disease | |
| US4548932A (en) | 3-Amino-4-oxo-2,3,4,5-tetrahydro-1,5-benzoxazepine derivatives | |
| WO2014204730A1 (en) | Bace inhibitors | |
| HUT71494A (en) | Pharmaceutical compositions containing of condensed heterocyclic amino acid derivatives | |
| KR100818431B1 (ko) | 벤조티아디아진 화합물, 이를 제조하는 방법 및 이를함유하는 약제 조성물 | |
| TW201617317A (zh) | 吡啶酮衍生物 | |
| KR20100083195A (ko) | 신규한 디아제니움디올레이트 유도체, 이들의 제조 방법 및 상기 화합물을 포함하는 약제 조성물 | |
| ES2228817T3 (es) | Nuevos modulados positivos alostericos del receptor de ampa (mpara), procedimiento para su preparacion y su uso como medicamentos. | |
| DK171821B1 (da) | 9-chlor-1,5-benzothiazepinderivater, fremgangsmåde til fremstilling deraf samt farmaceutisk præparat indeholdende disse | |
| DK168010B1 (da) | Tetrahydroisoquinolinforbindelser og farmaceutisk middel indeholdende en saadan forbindelse | |
| JP2003119137A (ja) | Ｈｉｖ阻害剤 | |
| DK165691B (da) | Tricykliske aminer afledt af 2,3,5,6,7,8-hexahydronaphtho(2,3-b)furan, fremgangsmaade til deres fremstilling og farmaceutiske midler indeholdende dem | |
| EA006608B1 (ru) | Нафтотиазиновые позитивные аллостерические модуляторы амра-рецепторов | |
| US7026475B2 (en) | Positive allosteric AMPA receptor modulators (PAARM), processes for preparing them, and their use as pharmaceutical compositions | |
| EP0053017A1 (en) | Amide derivatives | |
| CZ289468B6 (cs) | Thiazolobenzoheterocykly, způsob jejich přípravy a prostředky, které je obsahují | |
| NO327549B1 (no) | Benzo[G]kinolinderivater for behandling av glaukom og myopi | |
| KR20010083109A (ko) | 아미노산 유도체 및 이들을 유효 성분으로서 함유하는 약제 | |
| KR19990021835A (ko) | 축합 벤조디아제피논 유도체 및 이의 의약 조성물 | |
| AU2002345759A1 (en) | Naphtothiazine positive allosteric AMPA receptor modulators (PAARM) | |
| KR900007316B1 (ko) | 아민 유도체 및 이의 염, 이의 제조방법, 및 이를 함유하는 궤양 치료제 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |