EA003639B1 - Композиции валдекоксиба - Google Patents
Композиции валдекоксиба Download PDFInfo
- Publication number
- EA003639B1 EA003639B1 EA200100872A EA200100872A EA003639B1 EA 003639 B1 EA003639 B1 EA 003639B1 EA 200100872 A EA200100872 A EA 200100872A EA 200100872 A EA200100872 A EA 200100872A EA 003639 B1 EA003639 B1 EA 003639B1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- valdecoxib
- composition
- composition according
- concentration
- amount
- Prior art date
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/61—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Diabetes (AREA)
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- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
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- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Neurology (AREA)
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- Cardiology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Gastroenterology & Hepatology (AREA)
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- Reproductive Health (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16985699P | 1999-12-08 | 1999-12-08 | |
| US18163500P | 2000-02-10 | 2000-02-10 | |
| US20226900P | 2000-05-05 | 2000-05-05 | |
| PCT/US2000/032433 WO2001041762A2 (en) | 1999-12-08 | 2000-12-06 | Valdecoxib compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA200100872A1 EA200100872A1 (ru) | 2002-02-28 |
| EA003639B1 true EA003639B1 (ru) | 2003-08-28 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA200100872A EA003639B1 (ru) | 1999-12-08 | 2000-12-06 | Композиции валдекоксиба |
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| JP (1) | JP2003516353A (enExample) |
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| CN (2) | CN1679556A (enExample) |
| AR (1) | AR027896A1 (enExample) |
| AU (3) | AU1930301A (enExample) |
| BG (1) | BG105873A (enExample) |
| BR (1) | BR0008059A (enExample) |
| CA (1) | CA2362816C (enExample) |
| CO (1) | CO5261582A1 (enExample) |
| CR (1) | CR6458A (enExample) |
| CZ (1) | CZ20013163A3 (enExample) |
| EA (1) | EA003639B1 (enExample) |
| EE (1) | EE200100414A (enExample) |
| HK (1) | HK1041637A1 (enExample) |
| HR (1) | HRP20010582A2 (enExample) |
| HU (1) | HUP0200409A3 (enExample) |
| IL (2) | IL144763A0 (enExample) |
| IS (1) | IS6040A (enExample) |
| MY (1) | MY138227A (enExample) |
| NO (1) | NO20013858L (enExample) |
| NZ (1) | NZ513963A (enExample) |
| PE (1) | PE20010940A1 (enExample) |
| PL (1) | PL351069A1 (enExample) |
| SK (1) | SK12692001A3 (enExample) |
| TR (1) | TR200102297T1 (enExample) |
| TW (1) | TWI265808B (enExample) |
| WO (2) | WO2001041761A2 (enExample) |
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| NZ514896A (en) | 1998-10-30 | 2003-11-28 | Rj Innovation | A method of preventing parturient hypocalcemia in animals and compositions used therein |
| SK8562002A3 (en) | 1999-12-23 | 2003-10-07 | Pfizer Prod Inc | Pharmaceutical compositions providing enhanced drug concentrations |
| CN1638739A (zh) * | 2000-08-18 | 2005-07-13 | 法玛西雅厄普约翰美国公司 | 治疗成瘾性障碍的化合物 |
| AU2002303577B2 (en) * | 2001-05-04 | 2006-06-08 | Merck & Co., Inc. | Method and compositions for treating migraines |
| CN1633281A (zh) * | 2001-09-26 | 2005-06-29 | 法马西亚公司 | 口内崩解的伐地考昔组合物 |
| NZ532184A (en) * | 2001-10-10 | 2005-12-23 | Pharmacia Corp | Intraorally disintegrating valdecoxib compositions in which the excipient - a saccharide - is present in intimate association in an amount between 50% and 90% |
| GB0124459D0 (en) * | 2001-10-11 | 2001-12-05 | Novartis Ag | Organic compounds |
| MXPA04004290A (es) * | 2001-11-07 | 2004-08-11 | Pharmacia Corp | Composiciones de valdecoxib que se disgregan intraoralmente preparadas mediante un procedimiento de granulacion en lecho fluido. |
| BR0214081A (pt) * | 2001-11-13 | 2004-09-28 | Pharmacia Corp | Forma de dosagem oral de uma pró-droga de sulfonamida |
| CA2471951A1 (en) * | 2002-01-07 | 2003-07-17 | Pharmacia Corporation | Treatment of pain, inflammation, and inflammation-related disorders with a combination of a cyclooxygenase-2 selective inhibitor and aspirin |
| GB0201520D0 (en) * | 2002-01-23 | 2002-03-13 | Novartis Ag | Pharmaceutical uses |
| US7790905B2 (en) * | 2002-02-15 | 2010-09-07 | Mcneil-Ppc, Inc. | Pharmaceutical propylene glycol solvate compositions |
| WO2004026235A2 (en) * | 2002-09-20 | 2004-04-01 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions with improved dissolution |
| US7927613B2 (en) * | 2002-02-15 | 2011-04-19 | University Of South Florida | Pharmaceutical co-crystal compositions |
| AU2003246864A1 (en) * | 2002-02-22 | 2003-09-09 | Warner-Lambert Company Llc | Combinations of an alpha-2-delta ligand with a selective inhibitor of cyclooxygenase-2 |
| CA2477923C (en) * | 2002-03-01 | 2021-02-23 | University Of South Florida | Multiple-component solid phases containing at least one active pharmaceutical ingredient |
| GB0209265D0 (en) * | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| GB0209257D0 (en) * | 2002-04-23 | 2002-06-05 | Novartis Ag | Organic compounds |
| AU2003243699B2 (en) * | 2002-06-21 | 2009-01-15 | Transform Pharmaceuticals, Inc. | Pharmaceutical compositions with improved dissolution |
| CA2488526A1 (en) * | 2002-06-26 | 2004-01-08 | Pharmacia Corporation | Stable liquid parenteral parecoxib formulation |
| CA2494707A1 (en) * | 2002-08-30 | 2005-01-06 | Pharmacia Corporation | Pharmaceutical solid dosage forms exhibiting reproductible drug release profile |
| JP4494712B2 (ja) * | 2002-11-12 | 2010-06-30 | 大日本住友製薬株式会社 | マルチプルユニット型徐放性製剤 |
| ES2819854T3 (es) | 2002-11-22 | 2021-04-19 | Gruenenthal Gmbh | Uso de (1R,2R)-3-(3-dimetilamino-1-etil-2-metil-propil)-fenol para tratar el dolor inflamatorio |
| US8183290B2 (en) | 2002-12-30 | 2012-05-22 | Mcneil-Ppc, Inc. | Pharmaceutically acceptable propylene glycol solvate of naproxen |
| WO2005000294A1 (en) * | 2003-06-06 | 2005-01-06 | Pharmacia Corporation | Selective inhibitor and an anticonvulsant agent for the treatment of central nervous system disorders |
| US20050004224A1 (en) * | 2003-06-10 | 2005-01-06 | Pharmacia Corporation | Treatment of Alzheimer's disease with the R(-) isomer of a 2-arylpropionic acid non-steroidal anti-inflammatory drug alone or in combination with a cyclooxygenase-2 selective inhibitor |
| WO2005007156A1 (en) * | 2003-07-10 | 2005-01-27 | Pharmacia Corporation | Compositions of a cyclooxygenase-2 selective inhibitor and an angiotensin ii receptor antagonist for the treatment of central nervous system damage |
| MXPA06004499A (es) * | 2003-10-21 | 2006-06-27 | Pharmacia Corp | Metodo para el tratamiento o la prevencion de inflamacion respiratoria con un inhibidor de ciclooxigenasa 2 en combinacion con un inhibidor de fosfodiesterasa 4 y sus composiciones. |
| AU2005282784B2 (en) | 2004-09-01 | 2008-06-19 | Euro-Celtique S.A. | Opioid dosage forms having dose proportional steady state Cave and AUC and less than dose proportional single dose Cmax |
| RU2007139819A (ru) * | 2005-03-29 | 2009-05-10 | МакНЕЙЛ-Пи-Пи-Си, ИНК. (US) | Композиции с гидрофильными лекарствами в гидрофобной среде |
| CN102813655A (zh) * | 2005-05-05 | 2012-12-12 | 布里斯托尔-迈尔斯斯奎布公司 | Src/abl抑制剂配方 |
| US7942818B2 (en) * | 2006-02-01 | 2011-05-17 | University Of Florida Research Foundation, Inc. | Obstetric analgesia system |
| US8231907B2 (en) | 2006-03-21 | 2012-07-31 | Morehouse School Of Medicine | Nanoparticles for delivery of active agents |
| EP1923053A1 (en) * | 2006-09-27 | 2008-05-21 | Novartis AG | Pharmaceutical compositions comprising nilotinib or its salt |
| CA2677193C (en) | 2007-02-01 | 2015-06-30 | Takeda Pharmaceutical Company Limited | Tablet preparation without causing a tableting trouble |
| FR2963889B1 (fr) * | 2010-08-20 | 2013-04-12 | Debregeas Et Associes Pharma | Formulations a base de nalbuphine et leurs utilisations |
| CN110997667A (zh) * | 2017-08-14 | 2020-04-10 | 云杉生物科学公司 | 促肾上腺皮质激素释放因子受体拮抗剂 |
| EP3628005A4 (en) | 2017-08-14 | 2021-01-20 | Spruce Biosciences, Inc. | Corticotropin releasing factor receptor antagonists |
| CN108644512B (zh) * | 2018-07-09 | 2023-06-30 | 南京氟源化工管道设备有限公司 | 一种钢衬聚四氟乙烯三通及其模压工艺 |
| US20220072002A1 (en) * | 2018-12-24 | 2022-03-10 | Chia Tai Tianqing Pharmaceuticalgroup Co., Ltd. | Treatment use of pyrrolopyrimidine compound, and solid pharmaceutical composition of pyrrolopyrimidine compound |
| CN118948857A (zh) | 2020-08-12 | 2024-11-15 | 云杉生物科学公司 | 用于治疗多囊卵巢综合征的方法和组合物 |
| US11273128B1 (en) * | 2021-04-15 | 2022-03-15 | Sandoz Ag | Elagolix formulation |
| US11708372B2 (en) | 2021-11-19 | 2023-07-25 | Spruce Biosciences, Inc. | Crystalline composition of tildacerfont and methods of use and preparation thereof |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996025405A1 (en) * | 1995-02-13 | 1996-08-22 | G.D. Searle & Co. | Substituted isoxazoles for the treatment of inflammation |
| EP0863134A1 (en) * | 1997-03-07 | 1998-09-09 | Merck Frosst Canada Inc. | 2-(3,5-difluorophenyl)-3-(4-(methyl-sulfonyl)phenyl)-2-cyclopenten-1-one useful as an inhibitor of cyclooxygenase-2 |
| SA99191255B1 (ar) * | 1998-11-30 | 2006-11-25 | جي دي سيرل اند كو | مركبات سيليكوكسيب celecoxib |
| ATE306263T1 (de) * | 1999-03-10 | 2005-10-15 | Searle Llc | Zusammensetzungen zur verabreichung eines cyclooxygenase-2-hemmers an tiere |
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2000
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- 2000-12-04 CN CNA200510065059XA patent/CN1679556A/zh active Pending
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- 2000-12-04 JP JP2001543106A patent/JP2003516353A/ja active Pending
- 2000-12-04 EE EEP200100414A patent/EE200100414A/xx unknown
- 2000-12-04 CN CNB008059063A patent/CN1203852C/zh not_active Expired - Fee Related
- 2000-12-04 AU AU19303/01A patent/AU1930301A/en not_active Abandoned
- 2000-12-04 PL PL00351069A patent/PL351069A1/xx not_active Application Discontinuation
- 2000-12-04 BR BR0008059-4A patent/BR0008059A/pt not_active Application Discontinuation
- 2000-12-04 HR HR20010582A patent/HRP20010582A2/hr not_active Application Discontinuation
- 2000-12-04 CA CA002362816A patent/CA2362816C/en not_active Expired - Fee Related
- 2000-12-04 KR KR1020017010031A patent/KR100664479B1/ko not_active Expired - Fee Related
- 2000-12-04 IL IL14476300A patent/IL144763A0/xx active IP Right Grant
- 2000-12-04 TR TR2001/02297T patent/TR200102297T1/xx unknown
- 2000-12-06 CZ CZ20013163A patent/CZ20013163A3/cs unknown
- 2000-12-06 WO PCT/US2000/032433 patent/WO2001041762A2/en not_active Ceased
- 2000-12-06 NZ NZ513963A patent/NZ513963A/en unknown
- 2000-12-06 PE PE2000001298A patent/PE20010940A1/es not_active Application Discontinuation
- 2000-12-06 AR ARP000106472A patent/AR027896A1/es unknown
- 2000-12-06 AU AU19310/01A patent/AU777402B2/en not_active Ceased
- 2000-12-06 EP EP00982254A patent/EP1165072A2/en not_active Ceased
- 2000-12-06 HU HU0200409A patent/HUP0200409A3/hu unknown
- 2000-12-06 HK HK02102619.5A patent/HK1041637A1/zh unknown
- 2000-12-06 SK SK1269-2001A patent/SK12692001A3/sk unknown
- 2000-12-06 EA EA200100872A patent/EA003639B1/ru not_active IP Right Cessation
- 2000-12-06 MY MYPI20005731A patent/MY138227A/en unknown
- 2000-12-06 TW TW089125989A patent/TWI265808B/zh not_active IP Right Cessation
- 2000-12-06 US US09/731,349 patent/US20020013357A1/en not_active Abandoned
- 2000-12-11 CO CO00094074A patent/CO5261582A1/es unknown
-
2001
- 2001-08-06 IL IL144763A patent/IL144763A/en not_active IP Right Cessation
- 2001-08-07 IS IS6040A patent/IS6040A/is unknown
- 2001-08-08 NO NO20013858A patent/NO20013858L/no not_active Application Discontinuation
- 2001-09-04 BG BG105873A patent/BG105873A/bg unknown
- 2001-09-11 CR CR6458A patent/CR6458A/es not_active Application Discontinuation
-
2005
- 2005-01-04 AU AU2005200015A patent/AU2005200015A1/en not_active Abandoned
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Legal Events
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
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| MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM |