DZ3008A1 - Inhibiteurs de l'aspartyle protéase. - Google Patents
Inhibiteurs de l'aspartyle protéase.Info
- Publication number
- DZ3008A1 DZ3008A1 DZ000020A DZ000020A DZ3008A1 DZ 3008 A1 DZ3008 A1 DZ 3008A1 DZ 000020 A DZ000020 A DZ 000020A DZ 000020 A DZ000020 A DZ 000020A DZ 3008 A1 DZ3008 A1 DZ 3008A1
- Authority
- DZ
- Algeria
- Prior art keywords
- hiv
- aspartyl protease
- relates
- compounds
- protease inhibitors
- Prior art date
Links
- 239000003696 aspartic proteinase inhibitor Substances 0.000 title abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 3
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 241000713772 Human immunodeficiency virus 1 Species 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 108010017640 Aspartic Acid Proteases Proteins 0.000 abstract 1
- 102000004580 Aspartic Acid Proteases Human genes 0.000 abstract 1
- 108010016183 Human immunodeficiency virus 1 p16 protease Proteins 0.000 abstract 1
- 241000713340 Human immunodeficiency virus 2 Species 0.000 abstract 1
- 108010016191 Human immunodeficiency virus 2 p16 protease Proteins 0.000 abstract 1
- 230000036436 anti-hiv Effects 0.000 abstract 1
- 239000003443 antiviral agent Substances 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 229940124530 sulfonamide Drugs 0.000 abstract 1
- 150000003456 sulfonamides Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/19—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
- C07C311/29—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/42—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/18—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/18—Ethylenedioxybenzenes, not substituted on the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12004799P | 1999-02-12 | 1999-02-12 | |
SY109000 | 2000-02-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
DZ3008A1 true DZ3008A1 (fr) | 2004-03-27 |
Family
ID=26666304
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DZ000020A DZ3008A1 (fr) | 1999-02-12 | 2000-03-09 | Inhibiteurs de l'aspartyle protéase. |
Country Status (12)
Country | Link |
---|---|
EP (2) | EP1159278B1 (fr) |
JP (2) | JP4814427B2 (fr) |
AT (1) | ATE311391T1 (fr) |
AU (1) | AU3485800A (fr) |
DE (1) | DE60024419T2 (fr) |
DK (1) | DK1159278T3 (fr) |
DZ (1) | DZ3008A1 (fr) |
ES (1) | ES2254156T3 (fr) |
PE (1) | PE20010560A1 (fr) |
PT (1) | PT1159278E (fr) |
SI (1) | SI1159278T1 (fr) |
WO (1) | WO2000047551A2 (fr) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001046120A1 (fr) * | 1999-12-23 | 2001-06-28 | Aerojet Fine Chemicals Llc | Preparation amelioree de 2s,3s-n-isobutyl-n-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide chlorydrate et autres derives de diamines 2-hydroxy-1,3 |
WO2003024932A1 (fr) | 2001-09-18 | 2003-03-27 | Bristol-Myers Squibb Company | Sulfonamides de bis-amino acide comme inhibiteurs de la protease du vih |
AR037797A1 (es) * | 2001-12-12 | 2004-12-01 | Tibotec Pharm Ltd | Combinacion de inhibidores de proteasa dependientes del citocromo p450 |
US7157489B2 (en) * | 2002-03-12 | 2007-01-02 | The Board Of Trustees Of The University Of Illinois | HIV protease inhibitors |
SI2767539T1 (sl) | 2002-05-16 | 2017-10-30 | Janssen Sciences Ireland Uc | Psevdopolimorfne oblike inhibitorja proteaze HIV |
PE20040762A1 (es) * | 2002-11-27 | 2004-11-06 | Elan Pharm Inc | Ureas substituidas y carbamatos utiles para el tratamiento de la enfermedad de alzheimer |
US6632816B1 (en) * | 2002-12-23 | 2003-10-14 | Pharmacor Inc. | Aromatic derivatives as HIV aspartyl protease inhibitors |
AU2004299040A1 (en) * | 2003-12-15 | 2005-06-30 | Pharmacopeia, Inc. | Heterocyclic aspartyl protease inhibitors |
US7772411B2 (en) * | 2003-12-23 | 2010-08-10 | Tibotec Pharmaceuticals Ltd. | Process for the preparation of (3R,3aS,6aR)-hexahydrofuro [2,3-b] furan-3-yl (1S,2R)-3[[(4-aminophenyl) sulfonyl] (isobutyl) amino]-1-benzyl-2-hydroxypropylcarbamate |
TWI383975B (zh) | 2004-03-31 | 2013-02-01 | Tibotec Pharm Ltd | 製備(3R,3aS,6aR)六氫-呋喃并〔2,3-b〕呋喃-3-醇之方法 |
US7388008B2 (en) | 2004-08-02 | 2008-06-17 | Ambrilia Biopharma Inc. | Lysine based compounds |
CN101405293B (zh) | 2005-11-30 | 2013-03-13 | 中裕新药股份有限公司 | 天冬氨酰基蛋白酶抑制剂基于赖氨酸的前体药物及其制备方法 |
JP5401652B2 (ja) | 2006-09-21 | 2014-01-29 | タイメッド バイオロジクス インコーポレイテッド | プロテアーゼ阻害剤 |
US8153829B2 (en) | 2006-11-09 | 2012-04-10 | Janssen Pharmaceutica N.V. | Methods for the preparation of hexahydrofuro[2,3-B]furan-3-ol |
AU2008244306A1 (en) | 2007-04-27 | 2008-11-06 | Tibotec Pharmaceuticals Ltd. | Methods for the preparation of N-isobutyl-N-(2-hydroxy-3-amino-4-phenylbutyl)-p-nitrobenzenesulfonylamide derivatives |
GB2452952A (en) * | 2007-09-20 | 2009-03-25 | Npil Pharmaceuticals | N-[2-Hydroxy-3-(hydroxycarbonylamino)-3-methyl]-N-methyl-sulphonamide derivatives via N-[2-oxo-3-(hydroxycarbonylamino)-3-methyl]-N-methyl-imine skeleton |
WO2011061590A1 (fr) | 2009-11-17 | 2011-05-26 | Hetero Research Foundation | Nouveaux dérivés carboxamides comme inhibiteurs du vih |
TWI591152B (zh) | 2010-04-09 | 2017-07-11 | 日立化成股份有限公司 | 球狀螢光體、波長變換型太陽電池密封材、太陽電池模組及其製造方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4604402A (en) * | 1984-03-30 | 1986-08-05 | E. R. Squibb & Sons, Inc. | Hydroxy substituted ureido amino and imino acids |
US4629724A (en) * | 1984-12-03 | 1986-12-16 | E. R. Squibb & Sons, Inc. | Amino acid ester and amide renin inhibitors |
PT810209E (pt) * | 1992-08-25 | 2002-09-30 | Searle & Co | Hidroxietilamino-sulfonamidas de alfa- e beta-aminoacidos uteis como inibidores de protease retroviral |
JP4091654B2 (ja) * | 1992-08-25 | 2008-05-28 | ジー.ディー.サール、リミテッド、ライアビリティ、カンパニー | レトロウイルスプロテアーゼ阻害剤として有用なスルホニルアルカノイルアミノヒドロキシエチルアミノスルホンアミド |
US5723490A (en) * | 1992-09-08 | 1998-03-03 | Vertex Pharmaceuticals Incorporated | THF-containing sulfonamide inhibitors of aspartyl protease |
IS2334B (is) * | 1992-09-08 | 2008-02-15 | Vertex Pharmaceuticals Inc., (A Massachusetts Corporation) | Aspartyl próteasi hemjari af nýjum flokki súlfonamíða |
DK0885881T3 (da) * | 1992-10-30 | 2003-07-14 | Searle & Co | Sulfonylalkanoylaminohydroxyethylaminosulfaminsyrer, der er anvendelige som retrovirale proteaseinhibitorer |
US6143747A (en) * | 1995-01-20 | 2000-11-07 | G. D. Searle & Co. | Bis-sulfonamide hydroxyethylamino retroviral protease inhibitors |
US5691372A (en) * | 1995-04-19 | 1997-11-25 | Vertex Pharmaceuticals Incorporated | Oxygenated-Heterocycle containing sulfonamide inhibitors of aspartyl protease |
US5753660A (en) * | 1995-11-15 | 1998-05-19 | G. D. Searle & Co. | Substituted sulfonylalkanoylamino hydroxyethylamino sulfonamide retroviral protease inhibitors |
-
2000
- 2000-02-09 EP EP00913402A patent/EP1159278B1/fr not_active Expired - Lifetime
- 2000-02-09 DE DE60024419T patent/DE60024419T2/de not_active Expired - Lifetime
- 2000-02-09 PE PE2000000098A patent/PE20010560A1/es not_active Application Discontinuation
- 2000-02-09 ES ES00913402T patent/ES2254156T3/es not_active Expired - Lifetime
- 2000-02-09 AU AU34858/00A patent/AU3485800A/en not_active Abandoned
- 2000-02-09 JP JP2000598472A patent/JP4814427B2/ja not_active Expired - Fee Related
- 2000-02-09 SI SI200030800T patent/SI1159278T1/sl unknown
- 2000-02-09 PT PT00913402T patent/PT1159278E/pt unknown
- 2000-02-09 EP EP05025977.9A patent/EP1637518A3/fr not_active Withdrawn
- 2000-02-09 WO PCT/US2000/003288 patent/WO2000047551A2/fr active IP Right Grant
- 2000-02-09 DK DK00913402T patent/DK1159278T3/da active
- 2000-02-09 AT AT00913402T patent/ATE311391T1/de active
- 2000-03-09 DZ DZ000020A patent/DZ3008A1/fr active
-
2010
- 2010-05-17 JP JP2010113714A patent/JP2010184932A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
EP1637518A2 (fr) | 2006-03-22 |
PE20010560A1 (es) | 2001-05-04 |
AU3485800A (en) | 2000-08-29 |
JP2010184932A (ja) | 2010-08-26 |
JP4814427B2 (ja) | 2011-11-16 |
ES2254156T3 (es) | 2006-06-16 |
ATE311391T1 (de) | 2005-12-15 |
DE60024419D1 (en) | 2006-01-05 |
EP1159278B1 (fr) | 2005-11-30 |
DK1159278T3 (da) | 2006-04-10 |
EP1637518A3 (fr) | 2013-04-10 |
DE60024419T2 (de) | 2006-08-17 |
SI1159278T1 (sl) | 2006-06-30 |
EP1159278A2 (fr) | 2001-12-05 |
WO2000047551A3 (fr) | 2001-08-16 |
JP2002536430A (ja) | 2002-10-29 |
WO2000047551A2 (fr) | 2000-08-17 |
PT1159278E (pt) | 2006-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AP1717A (en) | Sulfonamide inhibitors of aspartyl protease. | |
MXPA03010538A (es) | Nuevas formulaciones que inhiben la proteasa aspartilo. | |
MY137777A (en) | Inhibitors of aspartyl protease | |
MX9603909A (es) | Derivados de sulfonamida como inhibidores de proteasa aspartilo. | |
CA2217737A1 (fr) | Sulfamides contenant tetrahydrofurane (thf) et agissant comme inhibiteurs de la protease aspartyle | |
AP9600827A0 (en) | Oxygenated-heterocycle containing sulfonamide inhibitors of aspartyl protease. | |
DZ3008A1 (fr) | Inhibiteurs de l'aspartyle protéase. | |
DE69624346T2 (de) | Verbindung der struktur aminosäure-hydroxyethylamino-sulfonamide als inhibitoren der retroviralen protease | |
PT1052250E (pt) | Inibidores de protease retroviral sulfonilalcanoilamino hidroxietilamino sulfonamidas | |
NO983435L (no) | Aspartylproteaseinhibitorer | |
EA199800661A1 (ru) | Ингибиторы аспартильных протеаз | |
MY135869A (en) | Inhibitors of aspartyl protease | |
MX9708057A (es) | Sulfonamidas que contienen thf inhibidoras de la aspartilproteasa. | |
MX9708055A (es) | Inhibidores de aspartil proteasa consistentes en sulfonamida que contiene heterociclo oxigenado. |