DOP2021000042A - Método de producción de derivados de 4-metoxipirrol - Google Patents

Método de producción de derivados de 4-metoxipirrol

Info

Publication number
DOP2021000042A
DOP2021000042A DO2021000042A DO2021000042A DOP2021000042A DO P2021000042 A DOP2021000042 A DO P2021000042A DO 2021000042 A DO2021000042 A DO 2021000042A DO 2021000042 A DO2021000042 A DO 2021000042A DO P2021000042 A DOP2021000042 A DO P2021000042A
Authority
DO
Dominican Republic
Prior art keywords
methoxypirrol
production method
derivatives production
derivatives
present disclosure
Prior art date
Application number
DO2021000042A
Other languages
English (en)
Inventor
Ki Eom Deok
Hyun Son Jeong
Taek Shin Jeong
Original Assignee
Dae Woong Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/KR2019/012122 external-priority patent/WO2020060213A1/ko
Application filed by Dae Woong Pharma filed Critical Dae Woong Pharma
Publication of DOP2021000042A publication Critical patent/DOP2021000042A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
    • C07D207/48—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

La presente divulgación se refiere a un método de fabricación de derivados de 4-metoxipirrol. La realización de la presente divulgación es útil para la producción industrial en masa de derivados de 4-metoxipirrol, ya que se mejoran el rendimiento y la eficiencia del procedimiento y se evita el uso de reactivos peligrosos y reactivos contaminantes para el medioambiente.
DO2021000042A 2018-09-19 2021-03-10 Método de producción de derivados de 4-metoxipirrol DOP2021000042A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR20180112196 2018-09-19
KR1020190110997A KR102126576B1 (ko) 2018-09-19 2019-09-06 4-메톡시 피롤 유도체의 제조 방법
PCT/KR2019/012122 WO2020060213A1 (ko) 2018-09-19 2019-09-19 4-메톡시 피롤 유도체의 제조 방법

Publications (1)

Publication Number Publication Date
DOP2021000042A true DOP2021000042A (es) 2021-05-31

Family

ID=69959291

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2021000042A DOP2021000042A (es) 2018-09-19 2021-03-10 Método de producción de derivados de 4-metoxipirrol

Country Status (21)

Country Link
US (1) US12110271B2 (es)
EP (1) EP3854784A4 (es)
JP (1) JP7253624B2 (es)
KR (1) KR102126576B1 (es)
CN (1) CN112739684B (es)
AU (1) AU2019343857B2 (es)
BR (1) BR112021005156A2 (es)
CA (1) CA3110830A1 (es)
CL (1) CL2021000639A1 (es)
CO (1) CO2021003195A2 (es)
DO (1) DOP2021000042A (es)
EC (1) ECSP21019076A (es)
JO (1) JOP20210040A1 (es)
MA (1) MA53673A (es)
MX (1) MX2021003137A (es)
PE (1) PE20211736A1 (es)
PH (1) PH12021550523A1 (es)
RU (1) RU2763287C1 (es)
SA (1) SA521421372B1 (es)
SG (1) SG11202101919VA (es)
TN (1) TN2021000035A1 (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102081920B1 (ko) 2016-03-25 2020-02-26 주식회사 대웅제약 1-(5-(2,4-다이플루오로페닐)-1-((3-플루오로페닐)술포닐)-4-메톡시-1h-피롤-3-일)-n-메틸메탄아민 염의 신규한 결정형
KR102233455B1 (ko) * 2017-06-21 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
KR102126576B1 (ko) 2018-09-19 2020-06-24 주식회사 대웅제약 4-메톡시 피롤 유도체의 제조 방법
CN116761589A (zh) 2020-12-18 2023-09-15 株式会社大熊制药 含1-(5-(2,4-二氟苯基)-1-((3-氟苯基)磺酰基)-4-甲氧基-1h-吡咯-3-基)-n-甲基甲胺的口服给药新制剂
KR102556500B1 (ko) * 2021-11-19 2023-07-19 하나제약 주식회사 피롤 유도체 또는 이의 약학적 또는 식품학적으로 허용 가능한 염, 및 이를 유효성분으로 포함하는 위장 질환의 예방, 개선 또는 치료용 조성물
WO2023229323A1 (ko) * 2022-05-23 2023-11-30 일동제약(주) 6-메톡시피리딘-3-일 유도체의 제조방법
WO2023229322A1 (ko) * 2022-05-23 2023-11-30 일동제약(주) 6-메톡시피리딘-3-일 유도체의 제조방법
CN117820193A (zh) * 2022-09-29 2024-04-05 安徽皓元药业有限公司 一种非苏拉赞盐酸盐晶型a及其制备方法
KR20240127136A (ko) * 2023-02-15 2024-08-22 주식회사 대웅제약 4-메톡시 피롤 유도체의 제조 방법

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1592996A (en) 1977-10-10 1981-07-15 Rolland Sa A Acylated pyrrole carboxylic acids and derivatives thereof
HU228844B1 (en) 2001-05-24 2013-06-28 Lilly Co Eli Pyrrole derivatives and pharmaceutical compositions containing them
US7691837B2 (en) 2002-09-20 2010-04-06 Lupin Limited Pyrrole derivatives as antimycobacterial compounds
ES2402362T3 (es) * 2004-09-30 2013-05-03 Takeda Pharmaceutical Company Limited Inhibidores de la bomba de protones
PE20110009A1 (es) 2005-08-30 2011-01-31 Takeda Pharmaceutical Derivados de pirrol como inhibidores de la secrecion acida
JP5207964B2 (ja) 2006-03-31 2013-06-12 武田薬品工業株式会社 酸分泌抑制薬
US7741364B2 (en) 2006-06-27 2010-06-22 Abbott Laboratories Pyrrole derivatives and their methods of use
US8933105B2 (en) * 2007-02-28 2015-01-13 Takeda Pharmaceutical Company Limited Pyrrole compounds
WO2009137657A1 (en) 2008-05-08 2009-11-12 Bristol-Myers Squibb Company 2-aryl glycinamide derivatives
UY32008A (es) 2008-07-28 2010-02-26 Takeda Pharmaceutical Composición farmacéutica
US8969387B2 (en) 2008-08-27 2015-03-03 Takeda Pharmaceutical Company Limited Pyrrole compounds
US8895558B2 (en) 2008-10-02 2014-11-25 Green Cross Corporation Arylpiperazine-containing pyrrole 3-carboxamide derivatives for treating depressive disorders
GB0823003D0 (en) 2008-12-17 2009-01-28 Syngenta Participations Ag Pyrrole derivatives with plant growth regulating properties
AU2013347383B2 (en) * 2012-11-19 2017-04-06 Jiangsu Hansoh Pharmaceutical Co., Ltd. Pyrrole sulfonamide derivative, preparation method for same, and medical application thereof
BR112015025729B1 (pt) 2013-04-10 2023-04-25 Daiichi Sankyo Company, Limited Métodos para resolver e para produzir um composto
JP2017071553A (ja) 2014-02-25 2017-04-13 味の素株式会社 ヘテロ原子−メチレン−ヘテロ環構造を有する新規化合物
CN104447491B (zh) 2014-11-19 2017-06-23 连云港恒运医药有限公司 含吡咯环质子泵抑制剂的半富马酸盐及其中间体和医药用途
KR101613245B1 (ko) 2015-04-27 2016-04-18 주식회사 대웅제약 신규의 4-메톡시 피롤 유도체 또는 이의 염 및 이를 포함하는 약학 조성물
CN106432191A (zh) * 2015-08-10 2017-02-22 陕西合成药业股份有限公司 一种新的吡咯类衍生物、其制备方法及其在医药上的应用
WO2017164575A1 (en) * 2016-03-25 2017-09-28 Daewoong Pharmaceutical Co.,Ltd. Novel acid addition salt of 1-(5-(2,4-difluorophenyl)-1-((3- fluorophenyl)sulfonyl)-4-methoxy-1h-pyrrol-3-yl)-n- methylmethanamine
KR20170113040A (ko) 2016-03-25 2017-10-12 주식회사 대웅제약 1-(5-(2,4-다이플루오로페닐)-1-((3-플루오로페닐)술포닐)-4-메톡시-1h-피롤-3-일)-n-메틸메탄아민의 신규한 산부가염
KR102081920B1 (ko) * 2016-03-25 2020-02-26 주식회사 대웅제약 1-(5-(2,4-다이플루오로페닐)-1-((3-플루오로페닐)술포닐)-4-메톡시-1h-피롤-3-일)-n-메틸메탄아민 염의 신규한 결정형
CN107879964B (zh) * 2016-09-29 2023-02-10 江苏柯菲平医药股份有限公司 1-(5-(2-氟苯基)-1-(3-(3-甲氧丙氧基)苯磺酰氯)-1h-吡咯-3-基)-n-甲基胺的制备方法
KR102233456B1 (ko) 2017-05-31 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
KR102233455B1 (ko) 2017-06-21 2021-03-29 주식회사 대웅제약 4-메톡시피롤 유도체의 중간체 제조 방법
CN108503621B (zh) * 2017-12-25 2021-09-14 上海中拓医药科技有限公司 一种富马酸沃诺拉赞的制备方法
KR102126576B1 (ko) 2018-09-19 2020-06-24 주식회사 대웅제약 4-메톡시 피롤 유도체의 제조 방법
WO2020060213A1 (ko) 2018-09-19 2020-03-26 주식회사 대웅제약 4-메톡시 피롤 유도체의 제조 방법
MX2023013985A (es) 2021-05-26 2023-12-12 Daewoong Pharmaceutical Co Ltd Contenedor de medicina que comprende la composicion farmaceutica liquida de 1-(5-(2,4-difluorofenil)-1-((3-fluorofenil)sulfonil)-4- metoxi-1h-pirrol-3-il)-n-metilmetanamina.

Also Published As

Publication number Publication date
AU2019343857B2 (en) 2021-12-02
SA521421372B1 (ar) 2024-01-25
PE20211736A1 (es) 2021-09-06
CO2021003195A2 (es) 2021-04-08
NZ773997A (en) 2024-03-22
CN112739684B (zh) 2024-06-04
KR20200033178A (ko) 2020-03-27
US12110271B2 (en) 2024-10-08
AU2019343857A1 (en) 2021-04-15
JP7253624B2 (ja) 2023-04-06
SG11202101919VA (en) 2021-04-29
MA53673A (fr) 2022-03-30
JP2021535934A (ja) 2021-12-23
MX2021003137A (es) 2021-05-14
RU2763287C1 (ru) 2021-12-28
CA3110830A1 (en) 2020-03-26
ECSP21019076A (es) 2021-05-31
KR102126576B1 (ko) 2020-06-24
BR112021005156A2 (pt) 2021-06-15
CN112739684A (zh) 2021-04-30
PH12021550523A1 (en) 2022-02-21
CL2021000639A1 (es) 2021-08-06
TN2021000035A1 (en) 2022-10-03
EP3854784A1 (en) 2021-07-28
JOP20210040A1 (ar) 2021-03-07
EP3854784A4 (en) 2022-03-30
US20210221770A1 (en) 2021-07-22

Similar Documents

Publication Publication Date Title
ECSP21019076A (es) Método de producción de derivados de 4-metoxipirrol
CL2018001790A1 (es) Procesos para preparar un inhibidor de jak1 y nuevas formas de este (divisional solicitud 201602748)
EA201891657A1 (ru) Интегрированный процесс ферментации и электролиза
PE20201263A1 (es) Suministro de cargas utiles a las celulas madre
BR112019000718A2 (pt) processo para a produção de geopolímero ou compósito de geopolímero
AR101867A1 (es) Apuntalante curable a baja temperatura
CO2017000367A2 (es) Producción microbiana de dioles grasos
BR112017000876A2 (pt) ?processo de fabricação de uma peça feita de material compósito de matriz de cerâmica, peça feita de material compósito de matriz de cerâmica, e, motor de turbina?
DOP2015000187A (es) Proceso de fabricación de vortioxetina
CL2020000869A1 (es) Enantiómeros de tiazoles sustituidos compuestos antivirales.
UY36557A (es) Composición ácida a base de leonardita y aminoácidos
CL2019000016A1 (es) Procesos novedosos para preparar estimuladores de guanilato ciclasa soluble.
BR112021022071A2 (pt) Substrato pulverulento obtido por craqueamento a vapor de uma biomassa sem agente auxiliar químico e suas utilizações
CL2021001511A1 (es) Novedosa psicosa-6-fosfato fosfatasa, composición para la producción de psicosa que comprende la misma y procedimiento para la producción de psicosa mediante el uso de la misma
AR113695A1 (es) Una d-psicosa 3-epimerasa y el uso de un método para producir d-psicosa
SV2016005302A (es) Tinturas reactivas fluorescentes, proceso para su producción y su uso
CU20170140A7 (es) Método para crear un compuesto a base de mercurio y el compuesto obtenido con el mismo
AR101951A1 (es) Síntesis de ent-progesterona e intermediarios de la misma
CO2021012174A2 (es) Microorganismo perteneciente al género staphylococcus que produce alulosa y procedimiento para la preparación de alulosa mediante el uso del mismo
UY37059A (es) Contenedores de vidrio de alta resistencia
PE20142111A1 (es) Desactivacion microbial de composiciones explosivas
UY37060A (es) Contenedores de vidrio de alta resistencia
Özdemir Energy management and cleaner production in an automotive supply industry
BR112019004813A2 (pt) processo para produção de perrenato de amônio
CO2020003240A2 (es) Proceso para elaborar compuestos orgánicos