DOP2013000043A - Composiciones y métodos para inhibir la unión de células madre y células progenitoras a tejido linfoide y para regenerar centros germinales en tejidos linfáticos - Google Patents

Composiciones y métodos para inhibir la unión de células madre y células progenitoras a tejido linfoide y para regenerar centros germinales en tejidos linfáticos

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Publication number
DOP2013000043A
DOP2013000043A DO2013000043A DO2013000043A DOP2013000043A DO P2013000043 A DOP2013000043 A DO P2013000043A DO 2013000043 A DO2013000043 A DO 2013000043A DO 2013000043 A DO2013000043 A DO 2013000043A DO P2013000043 A DOP2013000043 A DO P2013000043A
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Dominican Republic
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cells
compositions
methods
lymphatic
progenitating
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DO2013000043A
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English (en)
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Theresa Deisher
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Theresa Deisher
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Publication of DOP2013000043A publication Critical patent/DOP2013000043A/es

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    • A61K35/54Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
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    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K16/2878Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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    • C07K16/289Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD45
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    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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Abstract

La presente invención se refiere a composiciones y métodos para inhibir la unión de células madre a órganos y tejidos, que incluye el bloqueo de la unión de células madre a centros germinales presentes en el tejido linfático. Se describen composiciones y métodos para regenerar los centros germinales en el tejido linfático. En las composiciones se incluyen adyuvantes, agonistas del receptor de CD40, CD28 y IL-21 y antagonista de CD20. .
DO2013000043A 2010-08-18 2013-02-14 Composiciones y métodos para inhibir la unión de células madre y células progenitoras a tejido linfoide y para regenerar centros germinales en tejidos linfáticos DOP2013000043A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37494310P 2010-08-18 2010-08-18
US201161441485P 2011-02-10 2011-02-10
US201161449372P 2011-03-04 2011-03-04

Publications (1)

Publication Number Publication Date
DOP2013000043A true DOP2013000043A (es) 2013-09-30

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DO2013000043A DOP2013000043A (es) 2010-08-18 2013-02-14 Composiciones y métodos para inhibir la unión de células madre y células progenitoras a tejido linfoide y para regenerar centros germinales en tejidos linfáticos

Country Status (19)

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US (2) US20120045435A1 (es)
EP (2) EP3530274A1 (es)
JP (3) JP6096116B2 (es)
KR (3) KR101833204B1 (es)
CN (1) CN103167870B (es)
AU (1) AU2011291651B2 (es)
BR (1) BR112013003169B1 (es)
CA (1) CA2844109C (es)
CR (1) CR20130117A (es)
DO (1) DOP2013000043A (es)
ES (1) ES2738115T3 (es)
IL (1) IL224727B (es)
MX (1) MX368272B (es)
MY (1) MY179491A (es)
NZ (1) NZ607906A (es)
RU (1) RU2645069C2 (es)
SG (2) SG187840A1 (es)
WO (1) WO2012024519A2 (es)
ZA (2) ZA201301800B (es)

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KR20190017065A (ko) 2019-02-19
US20120045435A1 (en) 2012-02-23
US9962408B2 (en) 2018-05-08
CA2844109A1 (en) 2012-02-23
JP6437988B2 (ja) 2018-12-12
AU2011291651A1 (en) 2013-03-21
CR20130117A (es) 2013-05-31
EP2605765A2 (en) 2013-06-26
JP2014501694A (ja) 2014-01-23
WO2012024519A3 (en) 2012-04-19
MX2013001835A (es) 2013-02-26
JP2017081948A (ja) 2017-05-18
SG187840A1 (en) 2013-03-28
EP3530274A1 (en) 2019-08-28
BR112013003169B1 (pt) 2022-05-24
KR20180023040A (ko) 2018-03-06
JP2019059744A (ja) 2019-04-18
WO2012024519A2 (en) 2012-02-23
US20170128493A1 (en) 2017-05-11
NZ607906A (en) 2015-11-27
EP2605765B1 (en) 2019-05-08
WO2012024519A4 (en) 2012-06-28
CN103167870A (zh) 2013-06-19
JP6096116B2 (ja) 2017-03-15
ZA201402419B (en) 2015-12-23
SG10201600621VA (en) 2016-02-26
KR102173938B1 (ko) 2020-11-04
RU2645069C2 (ru) 2018-02-15
IL224727B (en) 2018-02-28
BR112013003169A2 (pt) 2016-06-28
AU2011291651B2 (en) 2016-01-14
RU2013110492A (ru) 2014-09-27
JP6716668B2 (ja) 2020-07-01
MX368272B (es) 2019-09-26
CA2844109C (en) 2018-11-06
KR101833204B1 (ko) 2018-03-02
MY179491A (en) 2020-11-08
ZA201301800B (en) 2014-07-30
ES2738115T3 (es) 2020-01-20
CN103167870B (zh) 2018-11-16
KR20140027901A (ko) 2014-03-07

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