DOP2002000449A - Sal sodica de un inhibidor de integradasa del vih. - Google Patents

Sal sodica de un inhibidor de integradasa del vih.

Info

Publication number
DOP2002000449A
DOP2002000449A DO2002000449A DO2002000449A DOP2002000449A DO P2002000449 A DOP2002000449 A DO P2002000449A DO 2002000449 A DO2002000449 A DO 2002000449A DO 2002000449 A DO2002000449 A DO 2002000449A DO P2002000449 A DOP2002000449 A DO P2002000449A
Authority
DO
Dominican Republic
Prior art keywords
sodium salt
hiv
inhibitor
integradasa
compound
Prior art date
Application number
DO2002000449A
Other languages
English (en)
Inventor
Wei Xu
Neville J Anthony
John V Lepore
Amar J Mahajan
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DOP2002000449A publication Critical patent/DOP2002000449A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Se divulga una sal de sodio del compuesto A, donde el compuesto A tiene la fórmula: Compuesto A E1 compuesto A es un iúhibidor de la integrasa del VIH, que es útil para prevenir o tratar la infección por el VIH, para demorar el inicio del SIDA y para el tratamiento del SIDA.
DO2002000449A 2001-08-17 2002-08-15 Sal sodica de un inhibidor de integradasa del vih. DOP2002000449A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31337301P 2001-08-17 2001-08-17

Publications (1)

Publication Number Publication Date
DOP2002000449A true DOP2002000449A (es) 2003-05-15

Family

ID=23215462

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2002000449A DOP2002000449A (es) 2001-08-17 2002-08-15 Sal sodica de un inhibidor de integradasa del vih.

Country Status (7)

Country Link
US (1) US6924282B2 (es)
EP (1) EP1430058A1 (es)
JP (1) JP2005501857A (es)
AR (1) AR036256A1 (es)
CA (1) CA2456206A1 (es)
DO (1) DOP2002000449A (es)
WO (1) WO2003016315A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ20031028A3 (cs) * 2000-10-12 2003-08-13 Merck & Co., Inc. Aza- a polyazanaftalenylkarboxamidy
AU2003218130A1 (en) * 2002-03-15 2003-09-29 Merck And Co., Inc. N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors
EP1646611A1 (en) * 2003-07-15 2006-04-19 Merck & Co., Inc. Hydroxypyridine cgrp receptor antagonists
DE602004021611D1 (de) * 2003-09-19 2009-07-30 Gilead Sciences Inc Azachinolinolphosphonatverbindungen als integraseinhibitoren
EP1742642B1 (en) * 2004-04-14 2008-10-15 Gilead Sciences, Inc. Phosphonate analogs of hiv integrase inhibitor compounds
MX2009003410A (es) 2006-09-29 2009-07-17 Idenix Pharmaceuticals Inc Fosfoindoles enantiomericamente puros como inhibidores de vih.

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2632639B1 (fr) 1988-06-09 1990-10-05 Sanofi Sa Derives d'amino-4 carboxy-3 naphtyridines, leur preparation et compositions pharmaceutiques qui les contiennent
AU1625192A (en) 1991-05-31 1992-12-03 Zeneca Limited Heterocyclic derivatives
US5681832A (en) 1995-02-17 1997-10-28 The United States Of America As Represented By The Department Of Health And Human Services Aroylaniline compounds, pharmaceutical compositions, and methods of using same to inhibit viral activity
US5945431A (en) 1996-03-15 1999-08-31 Biochem Therapeutics Incorporated Cytomegalovirus inhibiting compounds
EP0927164A1 (en) * 1996-09-10 1999-07-07 PHARMACIA & UPJOHN COMPANY 8-hydroxy-7-substituted quinolines as anti-viral agents
NZ334125A (en) 1996-09-25 2000-10-27 Zeneca Ltd Quinoline derivatives inhibiting the effect of growth factors such as VEGF
US6294547B1 (en) 1997-06-30 2001-09-25 Nippon Kayaku Kabushiki Kaisha Naphthyridine deratives or salts thereof
BR9811362A (pt) 1997-08-25 2000-08-22 Neurogen Corp Composto
RU2220960C2 (ru) 1997-12-22 2004-01-10 Фармация Энд Апджон Компани 4-гидрокси-3-хинолинкарбоксамиды и гидразиды, фармацевтическая композиция и способ лечения на их основе
US6262055B1 (en) 1998-06-03 2001-07-17 Merck & Co., Inc. HIV integrase inhibitors
US6306891B1 (en) 1998-06-03 2001-10-23 Merck & Co., Inc. HIV integrase inhibitors
US6380249B1 (en) 1998-06-03 2002-04-30 Merck & Co., Inc. HIV integrase inhibitors
AU5880600A (en) 1999-06-25 2001-01-31 Merck & Co., Inc. 1-(aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof
US6730682B2 (en) 2000-07-12 2004-05-04 Pharmacia & Upjohn Company Heterocycle carboxamides as antiviral agents
GB0017676D0 (en) 2000-07-19 2000-09-06 Angeletti P Ist Richerche Bio Inhibitors of viral polymerase
CZ20031028A3 (cs) * 2000-10-12 2003-08-13 Merck & Co., Inc. Aza- a polyazanaftalenylkarboxamidy
PL212914B1 (pl) 2001-10-26 2012-12-31 Angeletti P Ist Richerche Bio N-podstawione hydroksypirymidynonokarboksyamidy jako inhibitory integrazy HIV
ATE355064T1 (de) 2001-10-26 2006-03-15 Angeletti P Ist Richerche Bio Dihydroxypyrimidin-carbonsäueramid-hemmer der hiv-integrase

Also Published As

Publication number Publication date
WO2003016315A1 (en) 2003-02-27
JP2005501857A (ja) 2005-01-20
AR036256A1 (es) 2004-08-25
CA2456206A1 (en) 2003-02-27
US20030119823A1 (en) 2003-06-26
EP1430058A1 (en) 2004-06-23
US6924282B2 (en) 2005-08-02

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