DK720488D0 - Immunokompromitterede kimaerepattedyr og anvendelse heraf til fremstilling af celler og stoffer - Google Patents

Immunokompromitterede kimaerepattedyr og anvendelse heraf til fremstilling af celler og stoffer

Info

Publication number
DK720488D0
DK720488D0 DK720488A DK720488A DK720488D0 DK 720488 D0 DK720488 D0 DK 720488D0 DK 720488 A DK720488 A DK 720488A DK 720488 A DK720488 A DK 720488A DK 720488 D0 DK720488 D0 DK 720488D0
Authority
DK
Denmark
Prior art keywords
tissue
xenogeneic
thymus
lymph node
cells
Prior art date
Application number
DK720488A
Other languages
Danish (da)
English (en)
Other versions
DK720488A (da
Inventor
Joseph Mccrary Mccune
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22476130&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK720488(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Publication of DK720488D0 publication Critical patent/DK720488D0/da
Publication of DK720488A publication Critical patent/DK720488A/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
    • A01K67/027—New breeds of vertebrates
    • A01K67/0271—Chimeric animals, e.g. comprising exogenous cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56972—White blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56988—HIV or HTLV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2517/00—Cells related to new breeds of animals
DK720488A 1987-12-23 1988-12-23 Immunokompromitterede kimaerepattedyr og anvendelse heraf til fremstilling af celler og stoffer DK720488A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13717387A 1987-12-23 1987-12-23

Publications (2)

Publication Number Publication Date
DK720488D0 true DK720488D0 (da) 1988-12-23
DK720488A DK720488A (da) 1989-06-24

Family

ID=22476130

Family Applications (1)

Application Number Title Priority Date Filing Date
DK720488A DK720488A (da) 1987-12-23 1988-12-23 Immunokompromitterede kimaerepattedyr og anvendelse heraf til fremstilling af celler og stoffer

Country Status (8)

Country Link
EP (1) EP0322240B1 (fr)
JP (1) JP2801228B2 (fr)
AT (1) ATE119197T1 (fr)
AU (1) AU2754888A (fr)
DE (1) DE3853201T2 (fr)
DK (1) DK720488A (fr)
ES (1) ES2071620T3 (fr)
IL (1) IL88779A (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2981486B2 (ja) * 1988-06-14 1999-11-22 メディカル・バイオロジー・インスティチュート 哺乳動物の免疫系研究方法
US6673986B1 (en) 1990-01-12 2004-01-06 Abgenix, Inc. Generation of xenogeneic antibodies
US6075181A (en) * 1990-01-12 2000-06-13 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6150584A (en) * 1990-01-12 2000-11-21 Abgenix, Inc. Human antibodies derived from immunized xenomice
US6657103B1 (en) 1990-01-12 2003-12-02 Abgenix, Inc. Human antibodies derived from immunized xenomice
DE69120146T2 (de) * 1990-01-12 1996-12-12 Cell Genesys Inc Erzeugung xenogener antikörper
US6713610B1 (en) 1990-01-12 2004-03-30 Raju Kucherlapati Human antibodies derived from immunized xenomice
EP0438053B1 (fr) * 1990-01-15 1999-06-16 Yeda Research And Development Company Limited Implantation durable et développement d'une lignée hématopoiétique humaine chez des mammifères normaux
US5652373A (en) * 1990-01-15 1997-07-29 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
US5849288A (en) * 1990-01-15 1998-12-15 Yeda Research And Development Co. Ltd. Method for production of monoclonal antibodies in chimeric mice or rats having xenogeneic antibody-producing cells
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US5147784A (en) * 1990-04-12 1992-09-15 Systemix, Inc. T-lymphocyte progenitor cell assay
JPH04507109A (ja) * 1990-05-03 1992-12-10 システミックス　インコーポレイテッド 免疫無防備状態宿主中におけるヒトリンパ球組織
JPH05500617A (ja) * 1990-05-25 1993-02-12 システミックス，インコーポレイティド 免疫処理された宿主におけるヒト末梢血液細胞
DK9091D0 (da) * 1991-01-18 1991-01-18 Novo Nordisk As Fremgangsmaade til fremstilling af antistoffer
US5804160A (en) * 1991-06-04 1998-09-08 Yeda Research And Development Co. Ltd Animal model for hepatitis virus infection
US5849987A (en) * 1992-06-02 1998-12-15 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
US5858328A (en) * 1991-06-04 1999-01-12 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
DE69229254T2 (de) * 1991-10-30 1999-09-23 Idemitsu Kosan Co Verfahren zur Herstellung von menschlichen Lymphozyten und menschlichen Antikörpern; und so hergestellte Antikörper
US6353150B1 (en) * 1991-11-22 2002-03-05 Hsc Research And Development Limited Partnership Chimeric mammals with human hematopoietic cells
NL9102122A (nl) * 1991-12-18 1993-07-16 Tno Werkwijze voor het testen van antivirale middelen; daarvoor bruikbare proefdieren.
US5866757A (en) * 1992-06-02 1999-02-02 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
WO1994016080A1 (fr) * 1993-01-08 1994-07-21 Exemplar Corporation Procede in vitro/in vivo d'identification de medicaments anti-neoplasiques
GB9317766D0 (en) * 1993-08-26 1993-10-13 Agricultural & Food Res Animal models
US5972627A (en) * 1994-06-15 1999-10-26 Systemix, Inc. Method of purifying a population of cells enriched for dendritic and/or lymphoid progenitors and populations of cells obtained thereby
US5985660A (en) * 1994-06-15 1999-11-16 Systemix, Inc. Method of identifying biological response modifiers involved in dendritic and/or lymphoid progenitor cell proliferation and/or differentiation
WO1996001120A1 (fr) * 1994-07-03 1996-01-18 P.N. Gerolymatos S.A. Produits thymiques et applications
US6455756B1 (en) * 1994-08-12 2002-09-24 Novartis Ag Long term xenogeneic myeloid and lymphoid cell production in chimeric immunocompromised mice
US6015554A (en) * 1995-06-07 2000-01-18 Systemix, Inc. Method of reconstituting human lymphoid and dendritic cells
WO1996039811A1 (fr) * 1995-06-07 1996-12-19 Novartis Ag Animaux immunodeprimes a tissu synovial humain
US5986170A (en) 1995-11-13 1999-11-16 Corixa Corporation Murine model for human carcinoma
DK1500329T3 (da) 1996-12-03 2012-07-09 Amgen Fremont Inc Humane antistoffer, der specifikt binder TNF-alfa
JP2002503091A (ja) 1997-03-26 2002-01-29 リプロジェン，インコーポレイテッド 子宮内膜症マウスモデル
CA2284689C (fr) * 1997-04-09 2009-10-06 Lung-Ji Chang Modele animal aux fins d'une appreciation de vaccins
WO1999060846A1 (fr) * 1998-05-26 1999-12-02 Innogenetics N.V. Procede permettant d'augmenter des lymphocytes b de primates chez la souris immunodeprimee, et de produire de grands nombres de lymphocytes b specifiques de l'antigene pour la production d'anticorps monoclonaux de primates
US20070266448A1 (en) * 2006-05-11 2007-11-15 Alexander Lifke Method for the production of antibodies
JP2012531896A (ja) * 2009-06-29 2012-12-13 チェン，チンフェン ヒト化非ヒト哺乳動物を製造する方法
ES2591107T3 (es) 2009-10-06 2016-11-24 Regeneron Pharmaceuticals, Inc. Ratones modificados genéticamente e injerto
RU2730643C2 (ru) 2011-02-15 2020-08-24 Ридженерон Фармасьютикалз, Инк. Гуманизированные m-csf мыши
KR102594390B1 (ko) 2012-09-07 2023-10-27 예일 유니버시티 유전적으로 변형된 비-인간 동물 및 이것들의 사용 방법
CN104918483B (zh) 2012-11-05 2018-05-11 再生元制药公司 生成及使用经遗传修饰的非人动物的方法
ES2964597T3 (es) 2014-05-19 2024-04-08 Regeneron Pharma Ratones modificados genéticamente que expresan EPO humana
CN107896479B (zh) 2015-04-13 2021-07-13 再生元制药公司 人源化SIRPα-IL15敲入小鼠及其使用方法

Also Published As

Publication number Publication date
ATE119197T1 (de) 1995-03-15
EP0322240A3 (en) 1990-04-18
IL88779A (en) 1995-07-31
DE3853201D1 (de) 1995-04-06
IL88779A0 (en) 1989-07-31
EP0322240A2 (fr) 1989-06-28
JP2801228B2 (ja) 1998-09-21
AU2754888A (en) 1989-06-29
DK720488A (da) 1989-06-24
JPH0231632A (ja) 1990-02-01
EP0322240B1 (fr) 1995-03-01
ES2071620T3 (es) 1995-07-01
DE3853201T2 (de) 1995-09-14

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