DK674287A - Fremgangsmaade til fremstilling af optisk aktive dihydropyridinderivater - Google Patents
Fremgangsmaade til fremstilling af optisk aktive dihydropyridinderivaterInfo
- Publication number
- DK674287A DK674287A DK674287A DK674287A DK674287A DK 674287 A DK674287 A DK 674287A DK 674287 A DK674287 A DK 674287A DK 674287 A DK674287 A DK 674287A DK 674287 A DK674287 A DK 674287A
- Authority
- DK
- Denmark
- Prior art keywords
- procedure
- preparation
- optically active
- dihydropyridine derivatives
- active dihydropyridine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/945,760 US4920225A (en) | 1986-12-22 | 1986-12-22 | Resolution of 1,4-dihydropyridine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK674287D0 DK674287D0 (da) | 1987-12-21 |
| DK674287A true DK674287A (da) | 1988-06-23 |
Family
ID=25483522
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK674287A DK674287A (da) | 1986-12-22 | 1987-12-21 | Fremgangsmaade til fremstilling af optisk aktive dihydropyridinderivater |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4920225A (da) |
| EP (1) | EP0273349A3 (da) |
| JP (1) | JPS63185960A (da) |
| KR (1) | KR880007469A (da) |
| AU (1) | AU8284887A (da) |
| DK (1) | DK674287A (da) |
| FI (1) | FI875623A (da) |
| GB (1) | GB2200631A (da) |
| HU (1) | HUT45499A (da) |
| IE (1) | IE873469L (da) |
| IL (1) | IL84894A0 (da) |
| NO (1) | NO875239L (da) |
| ZA (1) | ZA879579B (da) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3737340A1 (de) * | 1987-11-04 | 1989-05-24 | Bayer Ag | Neue fluormethoxyphenyl-dihydropyridine, verfahren zur herstellung und ihre verwendung in arzneimitteln |
| GB8804630D0 (en) * | 1988-02-27 | 1988-03-30 | Pfizer Ltd | Preparation of r-& s-amlodipine |
| IT1230752B (it) * | 1989-02-17 | 1991-10-29 | Boehringer Biochemia Srl | Processo per la preparazione di 1,4 diidropiridine polisostituite in forma enantiomericamente pura. |
| CA2016707A1 (en) * | 1989-05-15 | 1990-11-15 | Graham A. Showell | Process for resolving 1-azabicyclo[2.2.1]heptane-3-carboxylates |
| JPH03141257A (ja) * | 1989-10-26 | 1991-06-17 | Green Cross Corp:The | ジヒドロピリジン誘導体 |
| US5100892A (en) * | 1990-11-13 | 1992-03-31 | Glaxo Inc. | Dihydropyridine vasodilator agents |
| US5135936A (en) * | 1991-03-05 | 1992-08-04 | Marion Merrell Dow Inc. | Isomers of 1-azabicyclo[2.2.2]oct-3-yl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinediacarboxylic and their use as calcium antagonists |
| US5210398A (en) * | 1991-06-14 | 1993-05-11 | Symbol Technologies, Inc. | Optical scanner with extended depth of focus |
| FR2719585B1 (fr) * | 1994-05-05 | 1996-08-02 | Lafon Labor | Procédé d'obtention de 1,4-dihydropyridines optiquement pures. |
| EP1191022A4 (en) | 1999-06-23 | 2002-09-18 | Ajinomoto Kk | NEW DIHYDROPYRIDINE DERIVATIVES |
| WO2002032878A1 (en) * | 2000-10-13 | 2002-04-25 | Eli Lilly And Company | Resolution process for preparation of substantially pure (r) and (s) enantiomers of 2-(4-nitroimidazolyl)-4-methoxyphenylpropionic acid and salts thereof |
| JP2007510728A (ja) * | 2003-11-03 | 2007-04-26 | ミオゲン インコーポレイティッド | 心血管疾患を治療するための１，４−ジヒドロピリジン化合物、薬学的組成物、および方法 |
| DE602004016547D1 (de) | 2003-11-03 | 2008-10-23 | Myogen Inc | 1,4-dihydropyridinverbindungen, pharmazeutische verbindungen, und verfahren zur behandlung von herzkreislauferkrankungen |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4370334A (en) * | 1975-07-02 | 1983-01-25 | Fujisawa Pharmaceutical Co., Ltd. | 1,4-Dihydro-pyridine derivatives and methods of using same |
| SE442298B (sv) * | 1978-06-30 | 1985-12-16 | Haessle Ab | 2,6-dimetyl-4-(2,3-diklorfenyl)-1,4-dihydropyridin-3,5-dikarboxylsyra-3-metylester-5-etylester i optisk aktiv form |
| SE429652B (sv) * | 1978-06-30 | 1983-09-19 | Haessle Ab | 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester |
| DE2935451A1 (de) * | 1979-09-01 | 1981-03-19 | Bayer Ag, 5090 Leverkusen | Optisch aktive 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arneimittel |
| CS228917B2 (en) * | 1981-03-14 | 1984-05-14 | Pfizer | Method of preparing substituted derivatives of 1,4-dihydropyridine |
| ZA83959B (en) * | 1982-03-10 | 1984-09-26 | Sandoz Ltd | 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them |
| JPS58208271A (ja) * | 1982-04-30 | 1983-12-03 | Kyowa Hakko Kogyo Co Ltd | １，４−ジヒドロピリジン誘導体 |
| FR2528431B1 (fr) * | 1982-06-15 | 1986-01-10 | Sandoz Sa | Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments |
| DE3247118A1 (de) * | 1982-12-20 | 1984-06-20 | Cassella Ag, 6000 Frankfurt | Neue substituierte 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| JPS59161392A (ja) * | 1983-03-04 | 1984-09-12 | Nippon Shinyaku Co Ltd | ジヒドロピリジン誘導体及びその製法 |
| EP0141222B1 (en) * | 1983-09-26 | 1989-04-12 | Nissan Chemical Industries Ltd. | Dihydropyridine-5-phosphonic acid cyclic ester |
| GB8412208D0 (en) * | 1984-05-12 | 1984-06-20 | Pfizer Ltd | Quinolone inotropic agents |
| DE3423105A1 (de) * | 1984-06-22 | 1986-01-02 | Bayer Ag, 5090 Leverkusen | Verfahren zur herstellung optisch aktiver 1,4-dihydropyridine |
| IL77843A (en) * | 1985-02-11 | 1989-07-31 | Syntex Inc | Dihydropyridine derivatives,process and novel intermediates for their preparation and pharmaceutical compositions containing them |
| US4595690A (en) * | 1985-02-11 | 1986-06-17 | Syntex (U.S.A.) Inc. | Antihypertensive dihydropyridine derivatives |
| US4761420A (en) * | 1986-06-13 | 1988-08-02 | Laboratoires Syntex S.A. | Antihypertensive dihydropyridine derivatives |
-
1986
- 1986-12-22 US US06/945,760 patent/US4920225A/en not_active Expired - Fee Related
-
1987
- 1987-12-15 NO NO875239A patent/NO875239L/no unknown
- 1987-12-17 ZA ZA879579A patent/ZA879579B/xx unknown
- 1987-12-21 HU HU875907A patent/HUT45499A/hu unknown
- 1987-12-21 GB GB08729735A patent/GB2200631A/en active Pending
- 1987-12-21 FI FI875623A patent/FI875623A/fi not_active Application Discontinuation
- 1987-12-21 DK DK674287A patent/DK674287A/da not_active Application Discontinuation
- 1987-12-21 KR KR1019870014603A patent/KR880007469A/ko not_active Application Discontinuation
- 1987-12-21 EP EP87118947A patent/EP0273349A3/en not_active Withdrawn
- 1987-12-21 AU AU82848/87A patent/AU8284887A/en not_active Abandoned
- 1987-12-21 IL IL84894A patent/IL84894A0/xx unknown
- 1987-12-21 JP JP62325159A patent/JPS63185960A/ja active Pending
- 1987-12-21 IE IE873469A patent/IE873469L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK674287D0 (da) | 1987-12-21 |
| EP0273349A3 (en) | 1990-02-14 |
| IL84894A0 (en) | 1988-06-30 |
| NO875239D0 (no) | 1987-12-15 |
| IE873469L (en) | 1988-06-22 |
| EP0273349A2 (en) | 1988-07-06 |
| HUT45499A (en) | 1988-07-28 |
| FI875623A (fi) | 1988-06-23 |
| KR880007469A (ko) | 1988-08-27 |
| ZA879579B (en) | 1989-08-30 |
| AU8284887A (en) | 1988-06-23 |
| JPS63185960A (ja) | 1988-08-01 |
| GB8729735D0 (en) | 1988-02-03 |
| US4920225A (en) | 1990-04-24 |
| FI875623A0 (fi) | 1987-12-21 |
| NO875239L (no) | 1988-06-23 |
| GB2200631A (en) | 1988-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |