DK669174A - - Google Patents

Info

Publication number
DK669174A
DK669174A DK669174A DK669174A DK669174A DK 669174 A DK669174 A DK 669174A DK 669174 A DK669174 A DK 669174A DK 669174 A DK669174 A DK 669174A DK 669174 A DK669174 A DK 669174A
Authority
DK
Denmark
Application number
DK669174A
Other languages
Danish (da)
Other versions
DK151339B (da
DK151339C (da
Inventor
M Numata
I Minamida
M Yamaoka
M Shiraishi
T Miyawaki
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP741521A external-priority patent/JPS57873B2/ja
Priority claimed from JP49020752A external-priority patent/JPS50111093A/ja
Priority claimed from JP4257474A external-priority patent/JPS57874B2/ja
Priority claimed from JP8262374A external-priority patent/JPS5652908B2/ja
Priority claimed from JP13138174A external-priority patent/JPS5512913B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK669174A publication Critical patent/DK669174A/da
Priority to DK005378A priority Critical patent/DK151026C/da
Publication of DK151339B publication Critical patent/DK151339B/da
Application granted granted Critical
Publication of DK151339C publication Critical patent/DK151339C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/36Sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
DK669174A 1973-12-25 1974-12-20 Analogifremgangsmaade til fremstilling af 7-(2-(2-imino-4-thiazolin-4-yl)-acetamido)-cephalosporinderivater DK151339C (da)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK005378A DK151026C (da) 1973-12-25 1978-01-05 7-(4-halogen-3-oxobutyryl)-cephalosporinderivater til anvendelse som mellemprodukt ved fremstilling af 7-(2-(2-imino-4-thiazolin-4-yl)-acetamido)-cephalosporinderivater

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
JP152174 1973-12-25
JP741521A JPS57873B2 (sv) 1973-12-25 1973-12-25
JP2075274 1974-02-20
JP49020752A JPS50111093A (sv) 1974-02-20 1974-02-20
JP4257474 1974-04-15
JP4257474A JPS57874B2 (sv) 1974-04-15 1974-04-15
JP8262374 1974-07-17
JP8262374A JPS5652908B2 (sv) 1974-07-17 1974-07-17
JP13138174A JPS5512913B2 (sv) 1974-11-13 1974-11-13
JP13138174 1974-11-13
KR7500661A KR800001569B1 (ko) 1973-12-25 1975-03-29 세팔로스포린 유도체의 제조법
KR750000661 1975-03-29

Publications (3)

Publication Number Publication Date
DK669174A true DK669174A (sv) 1975-09-08
DK151339B DK151339B (da) 1987-11-23
DK151339C DK151339C (da) 1988-05-30

Family

ID=27547623

Family Applications (1)

Application Number Title Priority Date Filing Date
DK669174A DK151339C (da) 1973-12-25 1974-12-20 Analogifremgangsmaade til fremstilling af 7-(2-(2-imino-4-thiazolin-4-yl)-acetamido)-cephalosporinderivater

Country Status (17)

Country Link
US (3) US4080498A (sv)
KR (1) KR800001569B1 (sv)
AR (3) AR230063A1 (sv)
CA (2) CA1070294A (sv)
CH (3) CH613976A5 (sv)
DE (3) DE2462736C2 (sv)
DK (1) DK151339C (sv)
FI (1) FI63585C (sv)
FR (1) FR2255077B1 (sv)
GB (1) GB1491018A (sv)
HK (1) HK15781A (sv)
IN (1) IN141283B (sv)
MY (1) MY8100256A (sv)
NL (1) NL164561C (sv)
NZ (1) NZ176206A (sv)
PH (2) PH12246A (sv)
SE (1) SE429234B (sv)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4379924A (en) * 1973-12-25 1983-04-12 Takeda Chemical Industries, Ltd. Cephalosporin derivatives
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins
US4348518A (en) 1974-05-05 1982-09-07 Hoffmann-La Roche Inc. Cephalosporins
DK151027C (da) * 1974-08-09 1988-03-07 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af 7alfa-methoxy-7beta-(2-aminothiazol-4-ylacetamido)cephalosporiner eller farmaceutisk acceptable salte eller estere deraf
ZA76757B (en) * 1975-03-18 1977-01-26 Smithkline Corp New cephalosporin compounds
US4093723A (en) * 1976-05-19 1978-06-06 Smithkline Corporation 7-Acyl-3-(sulfonic acid and sulfamoyl substituted tetrazolyl thiomethyl) cephalosporins
CA1088049A (en) * 1975-06-03 1980-10-21 Takashi Masugi 3-substituted-7-substituted alkanamido-3-cephem-4- carboxylic acid compounds and processes for preparation thereof
IL50546A (en) * 1975-10-30 1980-07-31 Smithkline Corp 7-acyl-3-(1-(2-sulfaminoethyl)tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid derivatives and pharmaceutical compositions containing them
FR2342733A1 (fr) * 1976-01-14 1977-09-30 Roussel Uclaf Derives de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
GB1575803A (en) 1976-03-09 1980-10-01 Fujisawa Pharmaceutical Co 3,7 disubstituted 3 cephem 4 carboxylic acid compounds andprocesses for the preparation thereof
US4041162A (en) * 1976-03-11 1977-08-09 Smithkline Corporation 7-Acyl-3-(sulfoalkyl substituted oxadiazolylthiomethyl) cephalosporins
FR2345153A1 (fr) * 1976-03-25 1977-10-21 Roussel Uclaf Nouvelles alcoyloximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
JPS5946237B2 (ja) * 1976-04-02 1984-11-10 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid
DK162391C (da) * 1976-04-12 1992-03-09 Fujisawa Pharmaceutical Co Analogifremgangsmaade til fremstilling af syn-isomerer af 3,7-disubstituerede 3-cephem-4-carboxylsyreforbindelser
FI771866A (sv) * 1976-06-28 1977-12-29 Fujisawa Pharmaceutical Co
JPS5321192A (en) * 1976-08-10 1978-02-27 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
JPS603314B2 (ja) * 1976-08-31 1985-01-26 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法
PH17188A (en) 1977-03-14 1984-06-14 Fujisawa Pharmaceutical Co New cephem and cepham compounds and their pharmaceutical compositions and method of use
US4117125A (en) * 1977-06-24 1978-09-26 Smithkline Corporation 7-Acylamino-3-[1-[2-(carboxymethylamino]ethyl) tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids
US4370326A (en) * 1977-09-13 1983-01-25 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds and composition
FR2410655A1 (fr) * 1977-12-05 1979-06-29 Roussel Uclaf Nouvelles oximes derivees de l'acide 3-substitue 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments
US4189479A (en) * 1977-12-22 1980-02-19 Takeda Chemical Industries, Ltd. Cephalosporin esters
JPS54160392A (en) * 1978-06-02 1979-12-19 Takeda Chem Ind Ltd Cephalosporin derivative and its preparation
US4220761A (en) * 1978-09-12 1980-09-02 Fujisawa Pharmaceutical Co., Ltd. 7-[Substituted oximinoacetamido]-3-[hydroxy alkyltetrazolo]cephalosporin derivatives
US4409215A (en) * 1979-11-19 1983-10-11 Fujisawa Pharmaceutical Co., Ltd. 7-Acylamino-3-substituted cephalosporanic acid derivatives and processes for the preparation thereof
EP0029998B1 (en) * 1979-11-30 1985-03-06 Fujisawa Pharmaceutical Co., Ltd. Cephem compounds, processes for their preparation and pharmaceutical compositions containing them
US4405617A (en) * 1980-02-11 1983-09-20 Fujisawa Pharmaceutical Co., Ltd. 3-(Propynyltetrazol)thiomethyl-3-cephems
CA1152489A (en) * 1980-03-05 1983-08-23 Takao Okuda ANTIMICROBIAL 7- (.alpha.-ACYLAMINO-.alpha.-ARYLACETAMIDO)-3- (SUBSTITUTED METHYL) CEPHALOSPORIN COMPOUNDS, THEIR COMPOSITIONS AND PRODUCTION THEREOF
EP0037797A3 (de) * 1980-03-11 1981-12-16 Ciba-Geigy Ag Cephalosporinverbindungen, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zusammensetzungen und ihre Verwendung
IT1148888B (it) * 1980-07-15 1986-12-03 Schiena Ricerche Di Composti antibiotici
US4338452A (en) * 1980-09-17 1982-07-06 Eli Lilly And Company 1-and 2-(1-Alkyl-1H-tetrazol-5-yl-methyl)-1H-tetrazol-5-thiols and 1-cyanomethyl tetrazole-5-thiol
US4346076A (en) * 1980-09-17 1982-08-24 Eli Lilly And Company Bis-tetrazoylmethyl substituted cephalosporin antibiotics
JPS58189186A (ja) * 1982-04-30 1983-11-04 Takeda Chem Ind Ltd セフアロスポリン誘導体
DE3239365A1 (de) * 1982-10-23 1984-04-26 Bayer Ag, 5090 Leverkusen Neue cephalosporine und verfahren zu ihrer herstellung
JPS59225191A (ja) * 1983-06-02 1984-12-18 Takeda Chem Ind Ltd 経口用セフアロスポリン誘導体
NZ208281A (en) * 1983-06-02 1986-11-12 Takeda Chemical Industries Ltd Cephalosporin ester derivatives and pharmaceutical compositions
JPS6038387A (ja) * 1983-08-10 1985-02-27 Takeda Chem Ind Ltd セフアロスポリンエステル
JPS60224693A (ja) * 1984-04-20 1985-11-09 Takeda Chem Ind Ltd セフアロスポリンエステル誘導体
GB9216759D0 (en) * 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
CN107987091A (zh) * 2017-11-07 2018-05-04 河北九派制药股份有限公司 一种盐酸头孢替安杂质3-甲基头孢替安盐酸盐的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK119672A (sv) *
US3218318A (en) * 1962-08-31 1965-11-16 Lilly Co Eli 7-heterocyclic-substituted-acylamido cephalosporins
US3557104A (en) * 1966-12-21 1971-01-19 Ciba Geigy Corp Derivatives of 7-acylamino-cephalosporanic acid
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
AU468437B2 (en) * 1971-03-09 1976-01-15 Takeda Chemical Industries, Ltd Cephalosporin derivatives
JPS5116436B1 (sv) * 1971-05-31 1976-05-24
JPS5747672B2 (sv) * 1973-10-13 1982-10-12
JPS5653557B2 (sv) * 1973-10-15 1981-12-19
NZ176206A (en) * 1973-12-25 1978-03-06 Takeda Chemical Industries Ltd Cephalosporins

Also Published As

Publication number Publication date
AR210589A1 (es) 1977-08-31
CH609701A5 (sv) 1979-03-15
CH615190A5 (sv) 1980-01-15
FR2255077A1 (sv) 1975-07-18
MY8100256A (en) 1981-12-31
DE2462736C2 (de) 1980-09-11
PH15904A (en) 1983-04-15
NL7416609A (nl) 1975-06-27
DK151339B (da) 1987-11-23
FI63585B (fi) 1983-03-31
FI63585C (fi) 1983-07-11
US4517361A (en) 1985-05-14
CA1070294A (en) 1980-01-22
AR218214A1 (es) 1980-05-30
SE429234B (sv) 1983-08-22
DK151339C (da) 1988-05-30
CH613976A5 (sv) 1979-10-31
US4080498A (en) 1978-03-21
HK15781A (en) 1981-05-01
AR230063A1 (es) 1984-02-29
FR2255077B1 (sv) 1978-07-21
DE2461478A1 (de) 1976-02-26
IN141283B (sv) 1977-02-12
CA1104125B (en) 1981-06-30
KR800001569B1 (ko) 1980-12-28
NL164561C (nl) 1981-01-15
PH12246A (en) 1978-12-12
SE7415914L (sv) 1975-06-26
NL164561B (nl) 1980-08-15
US4421912A (en) 1983-12-20
NZ176206A (en) 1978-03-06
DE2462893C2 (de) 1983-04-14
DE2461478C2 (de) 1982-04-15
GB1491018A (en) 1977-11-09
DE2462736B1 (de) 1980-01-03
FI365274A (sv) 1975-06-26

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Legal Events

Date Code Title Description
PUP Patent expired