DK666589A - D-vitamin homologer - Google Patents

D-vitamin homologer Download PDF

Info

Publication number
DK666589A
DK666589A DK666589A DK666589A DK666589A DK 666589 A DK666589 A DK 666589A DK 666589 A DK666589 A DK 666589A DK 666589 A DK666589 A DK 666589A DK 666589 A DK666589 A DK 666589A
Authority
DK
Denmark
Prior art keywords
homologist
vitamin
vitamin homologist
Prior art date
Application number
DK666589A
Other languages
Danish (da)
English (en)
Other versions
DK666589D0 (da
Inventor
Hector F Deluca
Heinrich K Schnoes
Kato L Perlman
Andrzej Kutner
Original Assignee
Wisconsin Alumni Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wisconsin Alumni Res Found filed Critical Wisconsin Alumni Res Found
Publication of DK666589D0 publication Critical patent/DK666589D0/da
Publication of DK666589A publication Critical patent/DK666589A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK666589A 1988-04-29 1989-12-22 D-vitamin homologer DK666589A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/187,680 US4927815A (en) 1988-04-29 1988-04-29 Compounds effective in inducing cell differentiation and process for preparing same
PCT/US1989/001633 WO1989010353A1 (en) 1988-04-29 1989-04-18 Compounds effective in inducing cell differentiation

Publications (2)

Publication Number Publication Date
DK666589D0 DK666589D0 (da) 1989-12-22
DK666589A true DK666589A (da) 1990-02-28

Family

ID=22690003

Family Applications (2)

Application Number Title Priority Date Filing Date
DK666589A DK666589A (da) 1988-04-29 1989-12-22 D-vitamin homologer
DK91890A DK89091D0 (da) 1988-04-29 1991-05-13 Fremgangsmaade til fremstilling af vitamin-d-forbindelser

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK91890A DK89091D0 (da) 1988-04-29 1991-05-13 Fremgangsmaade til fremstilling af vitamin-d-forbindelser

Country Status (15)

Country Link
US (2) US4927815A (ja)
EP (1) EP0375757A1 (ja)
JP (2) JPH0725730B2 (ja)
KR (1) KR930011151B1 (ja)
AU (1) AU630096B2 (ja)
CA (1) CA1340615C (ja)
DK (2) DK666589A (ja)
FR (1) FR2630740A1 (ja)
GB (1) GB2217715A (ja)
HU (1) HU206083B (ja)
IE (1) IE67868B1 (ja)
IL (1) IL90066A (ja)
IN (1) IN170659B (ja)
NL (1) NL8920414A (ja)
WO (1) WO1989010353A1 (ja)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250523A (en) * 1988-04-29 1993-10-05 Wisconsin Alumni Research Foundation Side chain unsaturated 1α-hydroxyvitanim D homologs
CA1339383C (en) * 1989-03-09 1997-08-26 Hector Floyd Deluca Method for preparing intermediates for the synthesis of steroid side chains in optically active form
DE3933034A1 (de) * 1989-10-02 1991-04-11 Schering Ag 24-homo-vitamin-d-derivate, verfahren zu ihrer herstellung
GB9007236D0 (en) * 1990-03-30 1990-05-30 Leo Pharm Prod Ltd Chemical compounds
US5459136A (en) * 1990-08-24 1995-10-17 Wisconsin Alumni Research Foundation Methods using vitamin D compounds for improvement of skin conditions
US5276061A (en) * 1990-08-24 1994-01-04 Wisconsin Alumni Research Foundation Cosmetic compositions containing 1α-hydroxyvitamin D homologs
US5756783A (en) * 1990-09-21 1998-05-26 Bone Care International, Inc. 1α-Hydroxy-24-EPI-vitamin D4
DE4221961A1 (de) * 1992-06-30 1994-01-05 Schering Ag 22-En-25-oxa-Derivate in der Vitamin D-Reihe, Verfahren zu ihrer Herstellung, diese Derivate enthaltenen pharmazeutische Präparate sowie deren Verwendung als Arzneimittel
US5380720A (en) * 1993-05-11 1995-01-10 Wisconsin Alumni Research Foundation Iodo vitamin D3 compounds and method for preparing same
PE28297A1 (es) * 1995-01-26 1997-08-20 Hoffmann La Roche Empleo dermatologico de derivados de vitamina d
US5744128A (en) * 1995-05-03 1998-04-28 Holick; Michael F. Use of emu oil for stimulating skin and hair growth
CA2175881A1 (en) * 1995-05-09 1996-11-10 Andrzej Kutner Vitamin d compounds and methods of preparing these compounds
AUPO727097A0 (en) * 1997-06-10 1997-07-03 Unisearch Limited Method of treatment of hepatoma and pharmaceutical compositions for use therein
US6521608B1 (en) 1998-03-27 2003-02-18 Oregon Health & Science University Vitamin D and its analogs in the treatment of tumors and other hyperproliferative disorders
EP1745787B1 (en) * 1999-04-01 2016-11-09 Johns Hopkins University NON-CALCEMIC, ANTIPROLIFERATIVE, TRANSCRIPTIONALLY ACTIVE SULFUR-CONTAINING ANALOGS OF 1-alpha 25-DIHYDROXY VITAMIN D3
AU2058701A (en) 1999-12-02 2001-06-12 F. Hoffmann-La Roche Ag Esters of vitamin D3 and uses thereof
US7166585B2 (en) * 2001-08-22 2007-01-23 Cytochroma Inc. 24-Sulfur-substituted analogs of 1α,25-dihydroxy vitamin D3
WO2003087048A2 (en) * 2002-04-11 2003-10-23 Instytut Farmaceutyczny Preparation of 24 alkyl analogs of cholecalciferol and non-racemic compounds
US20080039434A1 (en) * 2004-03-01 2008-02-14 Bioxell S. P.A. Treatment of Interstitial Cystitis with Vitamin D Compounds
WO2006051106A1 (en) 2004-11-12 2006-05-18 Bioxell Spa Combined use of vitamin d derivatives and anti-proliferative agents for treating bladder cancer
CN101711233A (zh) * 2007-04-18 2010-05-19 约翰·霍普金斯大学 低血钙、高抗增殖的钙三醇类似物
SG173119A1 (en) * 2009-01-27 2011-08-29 Berg Biosystems Llc Vitamin d3 and analogs thereof for alleviating side effects associated with chemotherapy
BR112012003372A2 (pt) 2009-08-14 2019-09-24 Berg Biosystems Llc vitamina d3 e análogos da mesma para o tratamento de alopecia.
US8754067B2 (en) 2010-11-12 2014-06-17 Wisconsin Alumni Research Foundation 22-haloacetoxy-homopregnacalciferol analogs and their uses
EP3003497B1 (en) 2013-05-29 2024-02-14 BPGbio, Inc. Preventing or mitigating chemotherapy induced alopecia using vitamin d
CN110981765A (zh) * 2019-11-07 2020-04-10 肇庆巨元生化有限公司 一种25-羟基维生素d3中间体的制备方法
CN112920096A (zh) * 2019-12-05 2021-06-08 四川大学 一种制备2-甲基-4-(苯磺酰基)-2-丁醇的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62500301A (ja) * 1984-10-04 1987-02-05 ウイスコンシン　アラムナイ　リサ−チ　フオンデ−シヨン ２４―ホモビタミンｄ誘導体
WO1986004333A1 (en) * 1985-01-17 1986-07-31 Wisconsin Alumni Research Foundation Vitamin d derivatives and methods for preparing same
US4717721A (en) * 1985-05-30 1988-01-05 Howard W. Bremer Sidechain homo-vitamin D compounds with preferential anti-cancer activity
IL77668A (en) * 1986-01-21 1989-03-31 Teva Pharma Production of cholecalciferol derivatives and novel intermediates used therefor
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
JP2711161B2 (ja) * 1988-04-21 1998-02-10 レオ・ファーマシューティカル・プロダクツ・リミテッド・エイ／エス（レーベンス・ケミスケ・ファブリック・プロデュクチオンスアクチーセルスカブ） 新規ビタミンｄ類似体
RU2057117C1 (ru) * 1988-04-29 1996-03-27 Висконсин Алюмни Рисерч Фаундейшн ГОМОЛОГИ 1α - ГИДРОКСИВИТАМИНА D3 С НЕНАСЫЩЕННОЙ БОКОВОЙ ЦЕПЬЮ, КОМПОЗИЦИЯ, СПОСОБСТВУЮЩАЯ СТИМУЛЯЦИИ И УСИЛЕНИЮ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА, СПОСОБ СТИМУЛЯЦИИ И УСИЛЕНИЯ ДИФФЕРЕНЦИАЦИИ ЗЛОКАЧЕСТВЕННЫХ КЛЕТОК ЛЕЙКЕМИИ ЧЕЛОВЕКА

Also Published As

Publication number Publication date
NL8920414A (nl) 1990-04-02
GB8909570D0 (en) 1989-06-14
KR900700449A (ko) 1990-08-13
FR2630740A1 (fr) 1989-11-03
DK89091A (da) 1991-05-13
DK89091D0 (da) 1991-05-13
HUT52475A (en) 1990-07-28
IN170659B (ja) 1992-05-02
JPH02504154A (ja) 1990-11-29
DK666589D0 (da) 1989-12-22
US4927815A (en) 1990-05-22
AU3573089A (en) 1989-11-24
HU892989D0 (en) 1990-06-28
KR930011151B1 (ko) 1993-11-24
AU630096B2 (en) 1992-10-22
IL90066A (en) 1995-12-08
IE891406L (en) 1989-10-29
JPH0725730B2 (ja) 1995-03-22
JPH0748343A (ja) 1995-02-21
US5061699A (en) 1991-10-29
JP2505713B2 (ja) 1996-06-12
GB2217715A (en) 1989-11-01
IL90066A0 (en) 1989-12-15
WO1989010353A1 (en) 1989-11-02
EP0375757A1 (en) 1990-07-04
IE67868B1 (en) 1996-05-01
HU206083B (en) 1992-08-28
CA1340615C (en) 1999-06-29

Similar Documents

Publication Publication Date Title
ATA901789A (de) Somatostatinpeptid
BR8806093A (pt) Trepano
DK233989D0 (da) Mejetaerskerskaerebord
ATA900689A (de) Calcitoninpeptide
DK666589A (da) D-vitamin homologer
DK188690D0 (da) Neutrocyt-aktiverende peptid-2
DK184489D0 (da) Bicyclodioner
DK201989D0 (da) Anaestesifordamper
DE68926597D1 (de) Mikrorechner
BR8902098A (pt) Eletrolisador
DK113291A (da) Homogent enzymimmunassay
DK238390A (da) Flyderoersbro
BR8906898A (pt) Jamela
DK137889D0 (da) Foldeaeske
DK182290A (da) Foldeaeske
DK165575C (da) Loeftesele
DE68926367D1 (de) Hydroxymethylcyclobutylpurine
DD277186A3 (de) Waelzlagerseparator
BR6800913U (pt) Trailer-sanitarios publico
BR8806404A (pt) Multiregua
BR8806232A (pt) Bau-casa
BR8907290A (pt) Diisopropilbenzeno-bis-peneoalcanoatos
BR8805477A (pt) Milran transpantaneiro
BR8804416A (pt) Papa-mosca
BR8803641A (pt) Tele-loto