DK64191A - 4-methyl-5-(2-(4-phenyl-1-piperazinyl)ethyl)thiazolderivater og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende thiazolderivaterne - Google Patents

4-methyl-5-(2-(4-phenyl-1-piperazinyl)ethyl)thiazolderivater og fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende thiazolderivaterne Download PDF

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Publication number
DK64191A
DK64191A DK064191A DK64191A DK64191A DK 64191 A DK64191 A DK 64191A DK 064191 A DK064191 A DK 064191A DK 64191 A DK64191 A DK 64191A DK 64191 A DK64191 A DK 64191A
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DK
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Prior art keywords
derivatives
thiazold
phenyl
piperazinyl
ethyl
Prior art date
Application number
DK064191A
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English (en)
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DK168861B1 (da
DK64191D0 (da
Inventor
Patrick Houziaux
Jean-Pierre Riffaud
Jean-Yves Lacolle
Bernard Danree
Original Assignee
Inst Rech Chim Biolog
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Inst Rech Chim Biolog filed Critical Inst Rech Chim Biolog
Publication of DK64191D0 publication Critical patent/DK64191D0/da
Publication of DK64191A publication Critical patent/DK64191A/da
Application granted granted Critical
Publication of DK168861B1 publication Critical patent/DK168861B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
DK064191A 1988-10-11 1991-04-10 4-methyl-5-(2-(4-phenyl-1-piperazinyl)ethyl)thiazolderivater og fremgangsmåde til fremstilling deraf, farmaceutiske midler indeholdende thiazolderivaterne og fremgangsmåde til fremstilling deraf og anvendelse af derivaterne til fremstilling af lægemidler DK168861B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR8813375 1988-10-11
FR8813375A FR2637596B1 (fr) 1988-10-11 1988-10-11 Methyl-4 ((aryl-4 piperazinyl-1)-2 ethyl)-5 thiazole et ses derives, leur procede de preparation et les medicaments en contenant
FR8900520 1989-10-10
PCT/FR1989/000520 WO1990003972A1 (fr) 1988-10-11 1989-10-10 Derives de methyl-4 ((phenyl-4 piperazinyl-1)-2 ethyl)-5 thiazole

Publications (3)

Publication Number Publication Date
DK64191D0 DK64191D0 (da) 1991-04-10
DK64191A true DK64191A (da) 1991-04-10
DK168861B1 DK168861B1 (da) 1994-06-27

Family

ID=9370913

Family Applications (1)

Application Number Title Priority Date Filing Date
DK064191A DK168861B1 (da) 1988-10-11 1991-04-10 4-methyl-5-(2-(4-phenyl-1-piperazinyl)ethyl)thiazolderivater og fremgangsmåde til fremstilling deraf, farmaceutiske midler indeholdende thiazolderivaterne og fremgangsmåde til fremstilling deraf og anvendelse af derivaterne til fremstilling af lægemidler

Country Status (9)

Country Link
US (1) US5120736A (da)
EP (1) EP0364350B1 (da)
JP (1) JPH04501263A (da)
AT (1) ATE100092T1 (da)
CA (1) CA2000247A1 (da)
DE (1) DE68912263T2 (da)
DK (1) DK168861B1 (da)
FR (1) FR2637596B1 (da)
WO (1) WO1990003972A1 (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2637596B1 (fr) * 1988-10-11 1992-09-04 Irceba Methyl-4 ((aryl-4 piperazinyl-1)-2 ethyl)-5 thiazole et ses derives, leur procede de preparation et les medicaments en contenant
FR2658514B1 (fr) * 1990-02-19 1992-06-19 Irceba Nouveaux derives du methyl-4 thiazole, leurs procedes de preparation et les compositions pharmaceutiques en contenant.
US5158953A (en) * 1991-08-13 1992-10-27 National Science Council 2-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazolin-5(6H)-ones (thiones), the preparation and use thereof
US5512677A (en) * 1991-08-13 1996-04-30 National Science Council 3-substituted methyl-2,3-dihydroimidazo 1,2-c!quinazoline derivatives, the preparation and use thereof
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
IT1254469B (it) * 1992-02-25 1995-09-25 Recordati Chem Pharm Derivati benzopiranici e benzotiopiranici
IT1258315B (it) * 1992-04-10 1996-02-22 Recordati Chem Pharm Derivati del flavone
US5760040A (en) 1994-03-30 1998-06-02 Zeria Pharmaceutical Co., Ltd. Indole derivative for treating overproduction of dihydrotestosterone

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1595923A1 (de) * 1965-02-20 1969-11-27 Merck Ag E 1-Aralkyl-4-(thiazolyl-2)-piperazine und Verfahren zu ihrer Herstellung
FR2594335B1 (fr) * 1986-02-14 1991-09-13 Irceba Derives de 5-(2-piperazinoethyl)-thiazole en tant que medicaments utiles en urologie
FR2637596B1 (fr) * 1988-10-11 1992-09-04 Irceba Methyl-4 ((aryl-4 piperazinyl-1)-2 ethyl)-5 thiazole et ses derives, leur procede de preparation et les medicaments en contenant
DE3923675A1 (de) * 1989-07-18 1991-01-24 Basf Ag Amonoalkylsubstituierte 2-aminothiazole und diese enthaltende therapeutische mittel

Also Published As

Publication number Publication date
EP0364350B1 (fr) 1994-01-12
FR2637596B1 (fr) 1992-09-04
DE68912263D1 (de) 1994-02-24
DK168861B1 (da) 1994-06-27
CA2000247A1 (fr) 1990-04-11
EP0364350A1 (fr) 1990-04-18
US5120736A (en) 1992-06-09
FR2637596A1 (fr) 1990-04-13
DE68912263T2 (de) 1994-06-01
DK64191D0 (da) 1991-04-10
ATE100092T1 (de) 1994-01-15
WO1990003972A1 (fr) 1990-04-19
JPH04501263A (ja) 1992-03-05

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed