DK628087A - Diazepinderivater - Google Patents
DiazepinderivaterInfo
- Publication number
- DK628087A DK628087A DK628087A DK628087A DK628087A DK 628087 A DK628087 A DK 628087A DK 628087 A DK628087 A DK 628087A DK 628087 A DK628087 A DK 628087A DK 628087 A DK628087 A DK 628087A
- Authority
- DK
- Denmark
- Prior art keywords
- diazepine
- Prior art date
Links
- LRANPJDWHYRCER-UHFFFAOYSA-N 1,2-diazepine Chemical compound N1C=CC=CC=N1 LRANPJDWHYRCER-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB868629875A GB8629875D0 (en) | 1986-12-15 | 1986-12-15 | Pyridazodiazepine derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK628087D0 DK628087D0 (da) | 1987-11-30 |
| DK628087A true DK628087A (da) | 1988-06-16 |
Family
ID=10609005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK628087A DK628087A (da) | 1986-12-15 | 1987-11-30 | Diazepinderivater |
Country Status (17)
| Country | Link |
|---|---|
| US (2) | US4757069A (pt) |
| EP (1) | EP0271795A3 (pt) |
| JP (1) | JPS63162693A (pt) |
| KR (1) | KR880007538A (pt) |
| AU (1) | AU602546B2 (pt) |
| CA (1) | CA1291478C (pt) |
| DK (1) | DK628087A (pt) |
| FI (1) | FI85482C (pt) |
| GB (1) | GB8629875D0 (pt) |
| HU (1) | HU198492B (pt) |
| IL (1) | IL84765A (pt) |
| MC (1) | MC1879A1 (pt) |
| NO (1) | NO166083C (pt) |
| NZ (1) | NZ222825A (pt) |
| PH (1) | PH23813A (pt) |
| PT (1) | PT86365B (pt) |
| ZA (1) | ZA879229B (pt) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5430145A (en) * | 1990-10-18 | 1995-07-04 | Merrell Dow Pharmaceuticals Inc. | Mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
| US5308841A (en) * | 1990-12-21 | 1994-05-03 | Merrell Dow Pharmaceuticals Inc. | Amino and nitro containing tricyclic compounds useful as inhibitors of ACE |
| US5455242A (en) * | 1991-09-27 | 1995-10-03 | Merrell Dow Pharmaceuticals Inc. | Carboxyalkyl tricyclic derivatives useful as inhibitors of enkephalinase and ace |
| US5457196A (en) * | 1991-09-27 | 1995-10-10 | Merrell Dow Pharmaceuticals Inc. | 2-substituted indane-2-carboxyalkyl derivatives useful as inhibitors of enkephalinase and ACE |
| CA2078758C (en) * | 1991-09-27 | 2003-12-09 | Alan M. Warshawsky | 2-substituted indane-2-mercaptoacetylamide derivatives useful as inhibitors of enkephalinase and ace |
| DE69317764T2 (de) * | 1992-02-14 | 1998-07-30 | Merrell Pharmaceuticals Inc., Cincinnati, Ohio | Aminoacetylmercaptoacetylamid derivate mit enkephalinase- und ace-hemmwirkung |
| ES2138622T3 (es) * | 1992-05-15 | 2000-01-16 | Merrell Pharma Inc | Derivados de mercaptoacetilamido piridazo(1,2-a)(1,2)diazepina utilizados como inhibidores de encefalinasa y eca. |
| US5420271A (en) * | 1992-08-24 | 1995-05-30 | Merrell Dow Pharmaceuticals, Inc. | 2-substituted indane-2-mercaptoacetylamide tricyclic derivatives useful as inhibitors of enkephalinase |
| ES2155852T3 (es) * | 1992-10-30 | 2001-06-01 | Merrell Pharma Inc | Derivados de lactama biciclica de mercaptoacetilamida utiles como inhibidores de encefalinasa y eca. |
| US5530013A (en) * | 1994-02-14 | 1996-06-25 | American Home Products Corporation | Venlafaxine in the inducement of cognition enhancement |
| CN1046512C (zh) * | 1994-02-14 | 1999-11-17 | 默里尔药物公司 | 巯基乙酰胺二硫化物衍生物，其制备方法及含有它们的药物组合物 |
| CN1069317C (zh) * | 1994-02-14 | 2001-08-08 | 默里尔药物公司 | 用作脑啡肽酶抑制剂的新的1,2－二氢化茚－2－巯基乙酰胺二硫化物衍生物 |
| EP0750631B1 (en) * | 1994-02-14 | 2000-04-05 | Merrell Pharmaceuticals Inc. | Novel mercaptoacetylamido 1,3,4,5-tetrahydro-benzo(c)azepin-3-one disulfide derivatives useful as inhibitors of enkephalinase and ace |
| WO1995021857A1 (en) * | 1994-02-14 | 1995-08-17 | Merrell Pharmaceuticals Inc. | Novel 2-substituted indane-2-mercaptoacetylamide disulfide derivatives useful as inhibitors of enkephalinase and ace |
| US5484783A (en) * | 1994-03-24 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | Hypocholesterolemic, antiatherosclerotic and hypotriglyceridemic mercaptoacetylamide and benzazapine derivatives |
| CN1144482A (zh) * | 1994-03-24 | 1997-03-05 | 默里尔药物公司 | 降低胆固醇、抗动脉粥样硬化和降低甘油三酯的巯基乙酰胺二硫化物衍生物 |
| JPH09510476A (ja) * | 1994-03-24 | 1997-10-21 | メリル・フアーマシユウテイカルズ・インコーポレイテツド | 低コレステロール血性、抗アテローム性動脈硬化性および低トリグリセライド血性のアミノアセチルメルカプト誘導体 |
| WO2001060879A1 (fr) * | 2000-02-17 | 2001-08-23 | China Petroleum & Chemical Corporation | Copolymere multisequence et son procede de preparation |
| GB0119305D0 (en) | 2001-04-12 | 2001-10-03 | Aventis Pharma Gmbh | Mercaptoacetylamide derivatives,a process for their preparation and their use |
| IE20070935A1 (en) * | 2007-12-21 | 2009-06-24 | Trinity College Dublin | Guanidine based compounds and their use in the treatment of mental and neurological disorders. |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4092438A (en) * | 1977-04-29 | 1978-05-30 | Carnation Company | Non-dairy coffee whitener containing acetate salt |
| GB2128984B (en) * | 1982-05-12 | 1985-05-22 | Hoffmann La Roche | Diaza-bicyclic compounds |
| GB8320764D0 (en) * | 1983-08-02 | 1983-09-01 | Rhodes Joseph Ltd | Bending machines |
| US4692438A (en) * | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
| EP0187037A3 (en) * | 1984-12-21 | 1988-03-23 | Takeda Chemical Industries, Ltd. | Piperidine derivatives, their production and use |
-
1986
- 1986-12-15 GB GB868629875A patent/GB8629875D0/en active Pending
-
1987
- 1987-11-24 US US07/124,749 patent/US4757069A/en not_active Expired - Fee Related
- 1987-11-30 DK DK628087A patent/DK628087A/da not_active Application Discontinuation
- 1987-12-07 EP EP87118047A patent/EP0271795A3/de not_active Ceased
- 1987-12-07 NZ NZ222825A patent/NZ222825A/en unknown
- 1987-12-08 CA CA000553720A patent/CA1291478C/en not_active Expired - Fee Related
- 1987-12-08 ZA ZA879229A patent/ZA879229B/xx unknown
- 1987-12-09 IL IL84765A patent/IL84765A/xx unknown
- 1987-12-09 AU AU82254/87A patent/AU602546B2/en not_active Ceased
- 1987-12-10 MC MC871934A patent/MC1879A1/xx unknown
- 1987-12-11 HU HU875592A patent/HU198492B/hu unknown
- 1987-12-14 PH PH36217A patent/PH23813A/en unknown
- 1987-12-14 NO NO875200A patent/NO166083C/no unknown
- 1987-12-14 KR KR870014258A patent/KR880007538A/ko not_active Application Discontinuation
- 1987-12-14 FI FI875483A patent/FI85482C/fi not_active IP Right Cessation
- 1987-12-14 JP JP62314308A patent/JPS63162693A/ja active Pending
- 1987-12-15 PT PT86365A patent/PT86365B/pt not_active IP Right Cessation
-
1988
- 1988-03-17 US US07/169,266 patent/US4782149A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FI875483A (fi) | 1988-06-16 |
| ZA879229B (en) | 1988-06-15 |
| NZ222825A (en) | 1990-11-27 |
| MC1879A1 (fr) | 1989-01-24 |
| FI85482C (fi) | 1992-04-27 |
| NO875200L (no) | 1988-06-16 |
| US4782149A (en) | 1988-11-01 |
| NO166083C (no) | 1991-05-29 |
| PH23813A (en) | 1989-11-23 |
| EP0271795A3 (de) | 1989-08-09 |
| FI85482B (fi) | 1992-01-15 |
| HUT47279A (en) | 1989-02-28 |
| CA1291478C (en) | 1991-10-29 |
| KR880007538A (ko) | 1988-08-27 |
| GB8629875D0 (en) | 1987-01-28 |
| EP0271795A2 (de) | 1988-06-22 |
| IL84765A0 (en) | 1988-05-31 |
| IL84765A (en) | 1991-06-30 |
| NO166083B (no) | 1991-02-18 |
| JPS63162693A (ja) | 1988-07-06 |
| US4757069A (en) | 1988-07-12 |
| PT86365A (en) | 1988-01-01 |
| PT86365B (pt) | 1990-11-20 |
| FI875483A0 (fi) | 1987-12-14 |
| HU198492B (en) | 1989-10-30 |
| AU602546B2 (en) | 1990-10-18 |
| DK628087D0 (da) | 1987-11-30 |
| AU8225487A (en) | 1988-06-16 |
| NO875200D0 (no) | 1987-12-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AHB | Application shelved due to non-payment |