DK596083A - Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse - Google Patents

Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse Download PDF

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Publication number
DK596083A
DK596083A DK596083A DK596083A DK596083A DK 596083 A DK596083 A DK 596083A DK 596083 A DK596083 A DK 596083A DK 596083 A DK596083 A DK 596083A DK 596083 A DK596083 A DK 596083A
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DK
Denmark
Prior art keywords
procedures
preparing
compound
carboxylic acid
acid amide
Prior art date
Application number
DK596083A
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Danish (da)
English (en)
Other versions
DK596083D0 (da
Inventor
Yasuji Harigaya
Hiroo Ogura
Mitsuo Mihara
Motosuke Yamanaka
Kiyomi Yamatsu
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of DK596083D0 publication Critical patent/DK596083D0/da
Publication of DK596083A publication Critical patent/DK596083A/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/192Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/12Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/57Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C233/59Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of rings other than six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by halogen atoms or by nitro or nitroso groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK596083A 1982-12-27 1983-12-23 Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse DK596083A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP57226685A JPS59118750A (ja) 1982-12-27 1982-12-27 カルボン酸アミド化合物およびその誘導体

Publications (2)

Publication Number Publication Date
DK596083D0 DK596083D0 (da) 1983-12-23
DK596083A true DK596083A (da) 1984-06-28

Family

ID=16849045

Family Applications (1)

Application Number Title Priority Date Filing Date
DK596083A DK596083A (da) 1982-12-27 1983-12-23 Carboxylsyreamidderivat, fremgangsmaade til fremstilling deraf samt laegemiddel indeholdende en saadan forbindelse

Country Status (18)

Country Link
US (1) US4661630A (ru)
JP (1) JPS59118750A (ru)
KR (1) KR840007714A (ru)
AU (1) AU2253183A (ru)
BE (1) BE898570A (ru)
CA (1) CA1202312A (ru)
CH (1) CH656875A5 (ru)
DE (1) DE3346814A1 (ru)
DK (1) DK596083A (ru)
ES (2) ES528409A0 (ru)
FR (1) FR2538386B1 (ru)
GB (1) GB2133006B (ru)
HU (1) HU189799B (ru)
IT (1) IT1170275B (ru)
NL (1) NL8304406A (ru)
PH (1) PH19459A (ru)
SE (1) SE8307119L (ru)
ZA (1) ZA839546B (ru)

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JPS59231057A (ja) * 1983-06-14 1984-12-25 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体
DE3334822A1 (de) * 1983-09-26 1985-04-04 Bayer Ag, 5090 Leverkusen Neue flammschutzmittel, ihre herstellung und ihre verwendung zur flammfestausruestung von polycarbonaten
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
KR20090090406A (ko) * 2000-12-18 2009-08-25 가부시키가이샤 이야쿠 분지 셋케이 겐쿠쇼 염증성 사이토카인 생산 유리 억제제
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
MXPA04000224A (es) 2001-07-10 2005-07-25 4Sc Ag Novedosos compuestos como agentes antiinflamatorios, inmunomoduladores y antiproliferativos.
DE10222895A1 (de) * 2002-05-23 2003-12-11 Bosch Gmbh Robert Hochdruckspeicher für Kraftstoffeinspritzsysteme mit integriertem Druckregelventil
CA2487891A1 (en) * 2002-06-05 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Inhibitors against the activation of ap-1 and nfat
CA2487900A1 (en) * 2002-06-05 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Immunity-related protein kinase inhibitors
EA008769B1 (ru) * 2002-06-05 2007-08-31 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. Лекарственное средство для лечения диабета
EP1514544A4 (en) * 2002-06-06 2009-01-07 Inst Med Molecular Design Inc HYPO-ALLERGENIC
EA009051B1 (ru) * 2002-06-06 2007-10-26 Инститьют Оф Медисинал Молекьюлар Дизайн. Инк. О-замещенные гидроксиарильные производные
CA2489091A1 (en) * 2002-06-10 2003-12-18 Institute Of Medicinal Molecular Design, Inc. Inhibitors against activation of nf-kappab
AU2003242108B2 (en) * 2002-06-10 2008-09-11 Institute Of Medicinal Molecular Design, Inc. Medicament for treatment of cancer
CN100490793C (zh) * 2002-06-11 2009-05-27 株式会社医药分子设计研究所 神经变性疾病治疗药
KR20050074949A (ko) * 2002-11-12 2005-07-19 엔오케이 가부시키가이샤 고무형상 탄성부품
US7365094B2 (en) 2002-12-23 2008-04-29 4Sc Ag Compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
WO2004056746A1 (en) * 2002-12-23 2004-07-08 4Sc Ag Cycloalkene dicarboxylic acid compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP1581478A1 (en) * 2002-12-23 2005-10-05 4Sc Ag Dhodh-inhibitors and method for their identification
US7247736B2 (en) * 2002-12-23 2007-07-24 4Sc Ag Method of identifying inhibitors of DHODH
EP1541198A1 (en) * 2003-12-05 2005-06-15 4Sc Ag Cycloalkyl compounds as anti-inflammatory, immunomodulatory and anti-proliferatory agents
EP2585054A1 (en) * 2010-06-24 2013-05-01 Allergan, Inc. Derivatives of cycloalkyl- and cycloalkenyl-1,2-dicarboxylic acid compounds having formyl peptide receptor like-1 (fprl-1) agonist or antagonist activity
UA108760C2 (uk) 2010-07-01 2015-06-10 Кальцієві солі сполуки як протизапальні, імуномодулюючі та антипроліферативні засоби
RS65563B1 (sr) 2018-03-16 2024-06-28 Immunic Ag Novi polimorfi kalcijumove soli kao anti-inflamatorni, imunomodulatorni i anti-proliferativni agensi
EP4056285A1 (en) 2021-03-12 2022-09-14 Atotech Deutschland GmbH & Co. KG Triazine silane compound and its usage as adhesion promotor
EP4057782A1 (en) 2021-03-12 2022-09-14 Atotech Deutschland GmbH & Co. KG Method for increasing adhesion strength between copper and an organic material and reducing halo and wedge void formation by modifying the copper surface and/or by using heteroaromatic silane compounds

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US2794811A (en) * 1954-06-03 1957-06-04 Allied Chem & Dye Corp Production of cis-cyclohexane-1, 2-dicarboxylic anhydride
US2959599A (en) * 1956-11-19 1960-11-08 Allied Chem Isomerization of cyclohexene-1, 2-dicarboxylic anhydrides
US3085096A (en) * 1961-05-31 1963-04-09 Petro Tex Chem Corp Preparation of cis-4-cyclohexene-1, 2-di-carboxylic acid anhydride
US3507904A (en) * 1966-04-01 1970-04-21 Herbert Schwartz Novel tetrahydrophthalamic acids and derivatives thereof
CH489993A (de) * 1967-12-19 1970-05-15 Ciba Geigy Das Pflanzenwachstum regulierendes und phytocides Mittel
US3922158A (en) * 1967-12-19 1975-11-25 Ciba Geigy Ag Method for inhibiting the growth of dicotyledonous plants
US3549655A (en) * 1967-12-21 1970-12-22 Dow Chemical Co N-(substituted phenyl) cyclobutanedicarboximides
US3745170A (en) * 1969-03-19 1973-07-10 Sumitomo Chemical Co Novel n-(3,5-dihalophenyl)-imide compounds
FR2059977A1 (ru) * 1969-08-14 1971-06-11 Socibre
US3825594A (en) * 1970-01-20 1974-07-23 Sandoz Ag Bis(trifluoromethyl)benzamides
US3654302A (en) * 1970-01-30 1972-04-04 Herbert Schwartz Tetrahydrophthalanils
US3987056A (en) * 1973-05-07 1976-10-19 Phillips Petroleum Company Disproportionation of n-aryl-1,2,3,6-tetrahydrophthalimides
US4002460A (en) * 1974-03-13 1977-01-11 Stauffer Chemical Company Triazine-antidote compositions and methods of use for cotton
US4025505A (en) * 1975-02-04 1977-05-24 Ciba-Geigy Corporation Aromatic dicarboxamides
CH615912A5 (ru) * 1975-06-18 1980-02-29 Ciba Geigy Ag
FR2369252B1 (fr) * 1976-10-29 1979-02-23 Inst Nat Rech Chimique Composes a,a-difluoroalkylbenzenes substitues et leur fabricationÿ
NL7714092A (nl) * 1976-12-22 1978-06-26 Monsanto Co Werkwijze voor het bereiden van nieuwe ftalamine- en nicotinezuren.
JPS5524127A (en) * 1978-08-08 1980-02-21 Morishita Seiyaku Kk 3,6-endomethylene-delta4-1,2,3,6-tetrahydrophtalimide derivative
EP0017994A3 (de) * 1979-04-20 1981-01-14 Ciba-Geigy Ag Cyclobutandicarbonsäureimide, Verfahren zu deren Herstellung und deren Verwendung als Fungizid; Zwischenprodukte
JPS56169669A (en) * 1980-05-30 1981-12-26 Takeda Chem Ind Ltd Hexahydroisoindole derivative, its preparation and herbicide
JPS59231057A (ja) * 1983-06-14 1984-12-25 Eisai Co Ltd カルボン酸アミド化合物およびその誘導体

Also Published As

Publication number Publication date
SE8307119L (sv) 1984-06-28
FR2538386B1 (fr) 1986-04-18
ES8608486A1 (es) 1986-06-16
CH656875A5 (de) 1986-07-31
BE898570A (fr) 1984-06-27
ES543810A0 (es) 1986-06-16
GB8333713D0 (en) 1984-01-25
GB2133006B (en) 1986-10-22
DK596083D0 (da) 1983-12-23
JPH0136819B2 (ru) 1989-08-02
HU189799B (en) 1986-07-28
GB2133006A (en) 1984-07-18
DE3346814A1 (de) 1984-06-28
PH19459A (en) 1986-04-18
ZA839546B (en) 1984-08-29
IT1170275B (it) 1987-06-03
ES8601859A1 (es) 1985-11-01
AU2253183A (en) 1984-07-05
FR2538386A1 (fr) 1984-06-29
US4661630A (en) 1987-04-28
ES528409A0 (es) 1985-11-01
NL8304406A (nl) 1984-07-16
CA1202312A (en) 1986-03-25
JPS59118750A (ja) 1984-07-09
IT8324351A0 (it) 1983-12-23
SE8307119D0 (sv) 1983-12-22
KR840007714A (ko) 1984-12-10

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