DK589589A - Renin-haemmende aminodiolderivater, deres fremstilling og anvendelse - Google Patents
Renin-haemmende aminodiolderivater, deres fremstilling og anvendelseInfo
- Publication number
- DK589589A DK589589A DK589589A DK589589A DK589589A DK 589589 A DK589589 A DK 589589A DK 589589 A DK589589 A DK 589589A DK 589589 A DK589589 A DK 589589A DK 589589 A DK589589 A DK 589589A
- Authority
- DK
- Denmark
- Prior art keywords
- inhibitive
- pure
- preparation
- aminodiol derivatives
- radical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0202—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-X-X-C(=0)-, X being an optionally substituted carbon atom or a heteroatom, e.g. beta-amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0205—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)3-C(=0)-, e.g. statine or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0207—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)4-C(=0), e.g. 'isosters', replacing two amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Crystallography & Structural Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Pyrrole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3839559A DE3839559A1 (de) | 1988-11-24 | 1988-11-24 | Renin-hemmende aminodiol-derivate |
Publications (2)
Publication Number | Publication Date |
---|---|
DK589589D0 DK589589D0 (da) | 1989-11-23 |
DK589589A true DK589589A (da) | 1990-05-25 |
Family
ID=6367727
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK589589A DK589589A (da) | 1988-11-24 | 1989-11-23 | Renin-haemmende aminodiolderivater, deres fremstilling og anvendelse |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0370454B1 (ja) |
JP (1) | JPH02193968A (ja) |
KR (1) | KR900007867A (ja) |
AT (1) | ATE104678T1 (ja) |
AU (1) | AU628109B2 (ja) |
DE (2) | DE3839559A1 (ja) |
DK (1) | DK589589A (ja) |
ES (1) | ES2054989T3 (ja) |
FI (1) | FI93645C (ja) |
HU (1) | HU204262B (ja) |
IL (1) | IL92405A0 (ja) |
NO (1) | NO177351C (ja) |
NZ (1) | NZ231485A (ja) |
PH (1) | PH27267A (ja) |
PT (1) | PT92388B (ja) |
ZA (1) | ZA898990B (ja) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3839128A1 (de) * | 1988-11-19 | 1990-05-31 | Hoechst Ag | Renin-hemmende dipeptide, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung |
GB8827308D0 (en) * | 1988-11-23 | 1988-12-29 | British Bio Technology | Compounds |
IE68045B1 (en) * | 1990-05-11 | 1996-05-15 | Abbott Lab | Renin inhibitors |
IE911774A1 (en) * | 1990-06-11 | 1991-12-18 | Akzo Nv | Pyridinylpiperazine derivatives |
CA2018801C (en) * | 1990-06-12 | 2000-08-22 | Pierre Louis Beaulieu | Antiherpes peptide derivatives having a 1,4-dioxo c n-terminus |
DE4021007A1 (de) * | 1990-07-02 | 1992-01-09 | Hoechst Ag | Aminodiol-derivate |
PL294870A1 (ja) * | 1991-06-21 | 1993-02-08 | Hoechst Ag |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3627877A1 (de) * | 1986-07-30 | 1988-02-04 | Hoechst Ag | Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung |
US5032577A (en) * | 1986-12-31 | 1991-07-16 | Abbott Laboratories | Peptidylaminodiols |
EP0309766B1 (en) * | 1987-09-29 | 1998-04-15 | Banyu Pharmaceutical Co., Ltd. | N-acylamino acid derivatives and their use |
IL90184A0 (en) * | 1988-05-09 | 1989-12-15 | Abbott Lab | Functionalized peptidyl aminodiols and-triols |
-
1988
- 1988-11-24 DE DE3839559A patent/DE3839559A1/de not_active Withdrawn
-
1989
- 1989-11-21 DE DE58907505T patent/DE58907505D1/de not_active Expired - Fee Related
- 1989-11-21 AT AT8989121499T patent/ATE104678T1/de active
- 1989-11-21 EP EP89121499A patent/EP0370454B1/de not_active Expired - Lifetime
- 1989-11-21 ES ES89121499T patent/ES2054989T3/es not_active Expired - Lifetime
- 1989-11-22 JP JP1302296A patent/JPH02193968A/ja active Pending
- 1989-11-22 NZ NZ231485A patent/NZ231485A/xx unknown
- 1989-11-22 IL IL92405A patent/IL92405A0/xx unknown
- 1989-11-22 FI FI895568A patent/FI93645C/fi not_active IP Right Cessation
- 1989-11-23 KR KR1019890017025A patent/KR900007867A/ko not_active Application Discontinuation
- 1989-11-23 NO NO894663A patent/NO177351C/no unknown
- 1989-11-23 PH PH39581A patent/PH27267A/en unknown
- 1989-11-23 PT PT92388A patent/PT92388B/pt not_active IP Right Cessation
- 1989-11-23 DK DK589589A patent/DK589589A/da not_active Application Discontinuation
- 1989-11-24 ZA ZA898990A patent/ZA898990B/xx unknown
- 1989-11-24 AU AU45475/89A patent/AU628109B2/en not_active Ceased
- 1989-11-24 HU HU896173A patent/HU204262B/hu not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
ATE104678T1 (de) | 1994-05-15 |
FI895568A0 (fi) | 1989-11-22 |
DE58907505D1 (de) | 1994-05-26 |
DK589589D0 (da) | 1989-11-23 |
FI93645C (fi) | 1995-05-10 |
JPH02193968A (ja) | 1990-07-31 |
PT92388B (pt) | 1995-07-18 |
HU896173D0 (ja) | 1990-02-28 |
IL92405A0 (en) | 1990-07-26 |
HUT52524A (en) | 1990-07-28 |
NO177351B (no) | 1995-05-22 |
PT92388A (pt) | 1990-05-31 |
NO894663D0 (no) | 1989-11-23 |
NZ231485A (en) | 1993-03-26 |
PH27267A (en) | 1993-05-04 |
EP0370454A2 (de) | 1990-05-30 |
EP0370454B1 (de) | 1994-04-20 |
KR900007867A (ko) | 1990-06-02 |
NO177351C (no) | 1995-08-30 |
FI93645B (fi) | 1995-01-31 |
EP0370454A3 (en) | 1990-10-24 |
HU204262B (en) | 1991-12-30 |
AU628109B2 (en) | 1992-09-10 |
NO894663L (no) | 1990-05-25 |
DE3839559A1 (de) | 1990-05-31 |
ZA898990B (en) | 1990-08-29 |
ES2054989T3 (es) | 1994-08-16 |
AU4547589A (en) | 1990-09-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ATS | Application withdrawn |