DK55488D0 - Fremstilling af guar-alfa-galactosidase ved hjaelp af vaertsorganismer transformeret ved rekombinante dna-metoder - Google Patents
Fremstilling af guar-alfa-galactosidase ved hjaelp af vaertsorganismer transformeret ved rekombinante dna-metoderInfo
- Publication number
- DK55488D0 DK55488D0 DK055488A DK55488A DK55488D0 DK 55488 D0 DK55488 D0 DK 55488D0 DK 055488 A DK055488 A DK 055488A DK 55488 A DK55488 A DK 55488A DK 55488 D0 DK55488 D0 DK 55488D0
- Authority
- DK
- Denmark
- Prior art keywords
- guar
- alpha
- galactosidase
- galactomannans
- alfa
- Prior art date
Links
- 102000002464 Galactosidases Human genes 0.000 title 1
- 108010093031 Galactosidases Proteins 0.000 title 1
- 108020004511 Recombinant DNA Proteins 0.000 title 1
- 102000005840 alpha-Galactosidase Human genes 0.000 abstract 5
- 108010030291 alpha-Galactosidase Proteins 0.000 abstract 5
- 244000303965 Cyamopsis psoralioides Species 0.000 abstract 3
- 229920000926 Galactomannan Polymers 0.000 abstract 3
- 229930182830 galactose Natural products 0.000 abstract 2
- 241000193830 Bacillus <bacterium> Species 0.000 abstract 1
- 241000894006 Bacteria Species 0.000 abstract 1
- 241000196324 Embryophyta Species 0.000 abstract 1
- 229920002907 Guar gum Polymers 0.000 abstract 1
- 241000235649 Kluyveromyces Species 0.000 abstract 1
- 241000208125 Nicotiana Species 0.000 abstract 1
- 241000235648 Pichia Species 0.000 abstract 1
- 241000235070 Saccharomyces Species 0.000 abstract 1
- 240000004808 Saccharomyces cerevisiae Species 0.000 abstract 1
- 125000003550 alpha-D-galactosyl group Chemical group C1([C@H](O)[C@@H](O)[C@@H](O)[C@H](O1)CO)* 0.000 abstract 1
- -1 beta-mannopyranosyl units Chemical group 0.000 abstract 1
- 230000037029 cross reaction Effects 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 150000004676 glycans Chemical class 0.000 abstract 1
- 229960002154 guar gum Drugs 0.000 abstract 1
- 235000010417 guar gum Nutrition 0.000 abstract 1
- 239000000665 guar gum Substances 0.000 abstract 1
- 230000001900 immune effect Effects 0.000 abstract 1
- 229920001282 polysaccharide Polymers 0.000 abstract 1
- 239000005017 polysaccharide Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
- C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2465—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1) acting on alpha-galactose-glycoside bonds, e.g. alpha-galactosidase (3.2.1.22)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP86200975 | 1986-06-03 | ||
GB868630255A GB8630255D0 (en) | 1986-12-18 | 1986-12-18 | Alpha-galactosidase |
GB868630719A GB8630719D0 (en) | 1986-12-23 | 1986-12-23 | Production of alphagalactosidase |
GB878710139A GB8710139D0 (en) | 1987-04-29 | 1987-04-29 | Production of alphagalactosidase |
GB878711061A GB8711061D0 (en) | 1987-05-11 | 1987-05-11 | Alpha-galactosidase |
EP87200955 | 1987-05-20 | ||
GB878712318A GB8712318D0 (en) | 1987-05-26 | 1987-05-26 | Alpha-galactosidase |
PCT/EP1987/000296 WO1987007641A1 (en) | 1986-06-03 | 1987-06-02 | Production of guar alpha-galactosidase by hosts transformed with recombinant dna methods |
Publications (2)
Publication Number | Publication Date |
---|---|
DK55488A DK55488A (da) | 1988-02-03 |
DK55488D0 true DK55488D0 (da) | 1988-02-03 |
Family
ID=27561917
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK055488A DK55488D0 (da) | 1986-06-03 | 1988-02-03 | Fremstilling af guar-alfa-galactosidase ved hjaelp af vaertsorganismer transformeret ved rekombinante dna-metoder |
Country Status (9)
Country | Link |
---|---|
US (2) | US5082778A (ja) |
JP (1) | JPH082296B2 (ja) |
KR (1) | KR930010770B1 (ja) |
AT (1) | ATE117373T1 (ja) |
AU (1) | AU602703B2 (ja) |
CA (1) | CA1339101C (ja) |
DE (1) | DE3750998T2 (ja) |
DK (1) | DK55488D0 (ja) |
WO (1) | WO1987007641A1 (ja) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL80510A0 (en) * | 1985-11-08 | 1987-02-27 | Genetics Inst | Improved yeast strains |
US20040064855A1 (en) * | 1988-02-26 | 2004-04-01 | Large Scale Biology Corporation | Production of lysosomal enzymes in plants by transient expression |
US6846968B1 (en) * | 1988-02-26 | 2005-01-25 | Large Scale Biology Corporation | Production of lysosomal enzymes in plants by transient expression |
US6004776A (en) * | 1989-07-07 | 1999-12-21 | Unilever Patent Holdings, B.V. | Process for preparing a protein by a fungus transformed by multicopy integration of an expression vector |
JP3273609B2 (ja) * | 1989-07-07 | 2002-04-08 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 発現ベクターのマルチコピー組込みにより形質転換した真菌による蛋白質の製法 |
WO1992013951A1 (en) * | 1991-02-04 | 1992-08-20 | The Salk Institute Biotechnology/Industrial Associates, Inc. | Production of human serum albumin in methylotrophic yeast cells |
US5708141A (en) * | 1992-05-11 | 1998-01-13 | Corvas International, Inc. | Neutrophil inhibitors |
NZ261662A (en) * | 1992-12-24 | 1997-03-24 | Corvas Int Inc | Neutrophil inhibitory factor, its production, antagonists, use and compositions thereof |
DK38893D0 (da) | 1993-03-31 | 1993-03-31 | Novo Nordisk As | Dna |
CN1124981A (zh) * | 1993-05-28 | 1996-06-19 | 纳幕尔杜邦公司 | 水合乙醛酸/氨甲基膦酸二烷基酯混合物的制备方法 |
US6329191B1 (en) * | 1993-08-30 | 2001-12-11 | Hawaii Biotechnology Group, Inc. | DNA encoding recombinant coffee bean alpha-galactosidase |
WO1995007088A1 (en) * | 1993-09-08 | 1995-03-16 | New York Blood Center, Inc. | RECOMBINANT α-GALACTOSIDASE ENZYME AND cDNA ENCODING SAID ENZYME |
GB9320930D0 (en) * | 1993-10-12 | 1993-12-01 | Zeneca Ltd | Modified fruit |
AU4772596A (en) * | 1995-01-30 | 1996-08-21 | New York Blood Center, Inc., The | Recombinant alpha-galactosidase enzyme |
US6770468B1 (en) | 1999-09-14 | 2004-08-03 | Genzyme Glycobiology Research Institute, Inc. | Phosphodiester-α-GlcNAcase of the lysosomal targeting pathway |
US6537785B1 (en) | 1999-09-14 | 2003-03-25 | Genzyme Glycobiology Research Institute, Inc. | Methods of treating lysosomal storage diseases |
DE19961182B4 (de) * | 1999-12-18 | 2006-01-12 | Südzucker AG Mannheim/Ochsenfurt | Galactomannan-Oligosaccharide und Verfahren zu deren Herstellung sowie deren Verwendung |
US7767415B2 (en) | 2001-09-25 | 2010-08-03 | Velico Medical, Inc. | Compositions and methods for modifying blood cell carbohydrates |
US6800472B2 (en) | 2001-12-21 | 2004-10-05 | Genzyme Glycobiology Research Institute, Inc. | Expression of lysosomal hydrolase in cells expressing pro-N-acetylglucosamine-1-phosphodiester α-N-acetyl glucosimanidase |
US6905856B2 (en) * | 2001-12-21 | 2005-06-14 | Genzyme Glycobiology Research Institute, Inc. | Soluble GlcNAc phosphotransferase |
US20030124652A1 (en) * | 2001-12-21 | 2003-07-03 | Novazyme Pharmaceuticals, Inc. | Methods of producing high mannose glycoproteins in complex carbohydrate deficient cells |
ES2351296B8 (es) * | 2009-04-08 | 2012-07-03 | Universidade Da Coruña | Cepas de s. cerevisiae capaces de crecer en medios con melibiosa, estaquiosa y rafinosa. |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3122216A1 (de) * | 1981-06-04 | 1982-12-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung eines mikroorganismus, welcher (alpha)-galactosidase, aber keine invertase bildet, so erhaltener mikroorganismus und seine verwendung |
JP2608540B2 (ja) * | 1982-05-19 | 1997-05-07 | ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ | クルイベロミセス種のためのクローニング系 |
US4548904A (en) * | 1982-12-03 | 1985-10-22 | Molecular Genetics Research & Development | Protein sequencing method |
NL8300698A (nl) * | 1983-02-24 | 1984-09-17 | Univ Leiden | Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten. |
DK147484A (da) * | 1983-03-11 | 1984-09-12 | Unilever Nv | Oparbejdning af polysaccharider |
NZ207925A (en) * | 1983-04-25 | 1988-05-30 | Genentech Inc | Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture |
EP0129268B1 (en) * | 1983-05-19 | 1989-10-04 | Unilever N.V. | Improvements in the expression of newly introduced genes in yeast cells |
NL8400687A (nl) * | 1984-03-02 | 1985-10-01 | Unilever Nv | Recombinant plasmiden; recombinant plasmiden bevattende bacterien; werkwijze voor het bereiden of vervaardigen van een zuivelproduct; werkwijze voor het bereiden van een eiwit. |
EP0423890A3 (en) * | 1984-07-27 | 1991-07-03 | Unilever Nv | Use of oxidoreductases in bleaching and/or detergent compositions and their preparation by microorganisms engineered by recombinant dna technology |
EP0174585A3 (en) * | 1984-09-14 | 1987-12-23 | Miles Laboratories, Inc. | Promoters and the use thereof in the expression of unfused procaryotic or eucaryotic proteins in yeast |
DK153568C (da) * | 1985-02-12 | 1988-12-05 | Novo Industri As | Alfa-galactomannangalactosidase og middel indeholdende denne |
FI861548A0 (fi) * | 1986-04-11 | 1986-04-11 | Alko Ab Oy | Nya jaeststammar vari med gentekniska foerfaranden infoerts en -galaktosidasgen och foerfaranden foer industriellt utnyttjande av dylika jaeststammar. |
-
1987
- 1987-06-01 CA CA000538543A patent/CA1339101C/en not_active Expired - Lifetime
- 1987-06-02 US US07/165,995 patent/US5082778A/en not_active Expired - Lifetime
- 1987-06-02 JP JP62503901A patent/JPH082296B2/ja not_active Expired - Lifetime
- 1987-06-02 AT AT87201041T patent/ATE117373T1/de not_active IP Right Cessation
- 1987-06-02 DE DE3750998T patent/DE3750998T2/de not_active Revoked
- 1987-06-02 KR KR1019880700119A patent/KR930010770B1/ko not_active IP Right Cessation
- 1987-06-02 AU AU75132/87A patent/AU602703B2/en not_active Ceased
- 1987-06-02 WO PCT/EP1987/000296 patent/WO1987007641A1/en unknown
-
1988
- 1988-02-03 DK DK055488A patent/DK55488D0/da not_active Application Discontinuation
-
1991
- 1991-06-26 US US07/721,409 patent/US5296365A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US5082778A (en) | 1992-01-21 |
US5296365A (en) | 1994-03-22 |
AU602703B2 (en) | 1990-10-25 |
ATE117373T1 (de) | 1995-02-15 |
KR880701284A (ko) | 1988-07-26 |
WO1987007641A1 (en) | 1987-12-17 |
KR930010770B1 (ko) | 1993-11-10 |
DK55488A (da) | 1988-02-03 |
DE3750998D1 (de) | 1995-03-02 |
CA1339101C (en) | 1997-07-29 |
JPH082296B2 (ja) | 1996-01-17 |
JPH01500242A (ja) | 1989-02-02 |
DE3750998T2 (de) | 1995-06-22 |
AU7513287A (en) | 1988-01-11 |
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