DK540686A - Cardiotonisk virksomme heterocycliske oxazoloner - Google Patents

Cardiotonisk virksomme heterocycliske oxazoloner

Info

Publication number
DK540686A
DK540686A DK540686A DK540686A DK540686A DK 540686 A DK540686 A DK 540686A DK 540686 A DK540686 A DK 540686A DK 540686 A DK540686 A DK 540686A DK 540686 A DK540686 A DK 540686A
Authority
DK
Denmark
Prior art keywords
oxazolons
heterocyclic
cardiotonic
cardiotonic effective
effective heterocyclic
Prior art date
Application number
DK540686A
Other languages
English (en)
Other versions
DK540686D0 (da
Inventor
Richard A Schnettler
Jr Winton D Jones
George P Claxton
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK540686D0 publication Critical patent/DK540686D0/da
Publication of DK540686A publication Critical patent/DK540686A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
DK540686A 1985-11-13 1986-11-12 Cardiotonisk virksomme heterocycliske oxazoloner DK540686A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/797,580 US4698353A (en) 1985-11-13 1985-11-13 Cardiotonic heterocyclic oxazolones

Publications (2)

Publication Number Publication Date
DK540686D0 DK540686D0 (da) 1986-11-12
DK540686A true DK540686A (da) 1987-05-14

Family

ID=25171234

Family Applications (1)

Application Number Title Priority Date Filing Date
DK540686A DK540686A (da) 1985-11-13 1986-11-12 Cardiotonisk virksomme heterocycliske oxazoloner

Country Status (21)

Country Link
US (1) US4698353A (da)
EP (1) EP0222358B1 (da)
JP (1) JPS62114975A (da)
KR (1) KR900000369B1 (da)
CN (1) CN1017150B (da)
AR (1) AR242207A1 (da)
AT (1) ATE62685T1 (da)
AU (1) AU586295B2 (da)
CA (1) CA1280754C (da)
DE (1) DE3678795D1 (da)
DK (1) DK540686A (da)
ES (1) ES2036518T3 (da)
FI (1) FI864596A (da)
GR (1) GR3001806T3 (da)
HU (1) HU197898B (da)
IL (1) IL80583A0 (da)
NO (1) NO168105C (da)
NZ (1) NZ218237A (da)
PH (1) PH23218A (da)
PT (1) PT83734B (da)
ZA (1) ZA868503B (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4670450A (en) * 1985-11-13 1987-06-02 Merrell Dow Pharmaceuticals Inc. Cardiotonic thiazolones
US4876352A (en) * 1988-09-14 1989-10-24 Schering Corporation Pressurized fluorination of hydroxy alkyl groups
US4886811A (en) * 1988-10-24 1989-12-12 Merrell Dow Pharmaceuticals Qunolyloxazole-2-ones useful as proteinkinase C inhibitors
US4990519A (en) * 1988-10-24 1991-02-05 Merrell Dow Pharmaceuticals Method of using quinolyloxazole-2-ones as proteinkinase C inhibitors
US4999431A (en) * 1988-10-24 1991-03-12 Merrell Dow Pharmaceuticals Process for preparing quinoline aldehyde and ketone derivatives
ZA908934B (en) * 1989-11-13 1991-08-28 Merrell Dow Pharma Novel pyridyloxazole-2-ones useful as proteinkinase c inhibitors
ZA908852B (en) * 1989-11-13 1991-09-25 Merrell Dow Pharma Treatment of multi-drug resistant tumors with pyridyloxazole-2-ones
US5063238A (en) * 1989-11-13 1991-11-05 Merrell Dow Pharmaceuticals Inc. Prevention of glycoprotein enveloped virus infectivity by pyridinyloxazole-2-ones
ZA908935B (en) * 1989-11-13 1991-08-28 Merrell Dow Pharma Prevention of glycoprotein enveloped virus infectivity by pyridinyloxazole-2-ones
US5182293A (en) * 1989-11-13 1993-01-26 Merrell Dow Pharmaceuticals Inc. Treatment of multi-drug resistant tumors with pyridyloxazole-2-ones
DK0539575T3 (da) * 1991-05-14 1997-10-27 Merrell Pharma Inc Hæmning af metastasering hos kræftpatienter med pyridyloxasol-2-oner.
CN1064080C (zh) * 1997-06-26 2001-04-04 梁国坚 鹿茸细胞的工业化生产方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3538104A (en) * 1969-02-28 1970-11-03 Geigy Chem Corp Pyridyl-2-imidazolones
US3879410A (en) * 1971-02-08 1975-04-22 Messrs Lab Guidotti & C S P A 4-Aryl-4-oxazolin-2-ones exhibiting myotonic and myorelaxing activity
SU427015A1 (ru) * 1972-04-21 1974-05-05 В. М. Дзиомко , А. В. Иващенко Способ получения замещенных 4-оксазолин-2-онов
JPS5111763A (en) * 1974-07-16 1976-01-30 Sankyo Co 55 chikan 44 okisazorin 22 onno seizoho
JPS5811867B2 (ja) * 1974-11-06 1983-03-04 東京田辺製薬株式会社 ５，５−ジメチル−４−フエニルオキサゾリジン−２−オン誘導体の製造方法
IT1109002B (it) * 1977-09-22 1985-12-16 Menarini Sas Derivati del 2 oxazolidone e loro metodi di preparazione
DE2935902A1 (de) * 1979-09-05 1981-04-02 A. Nattermann & Cie GmbH, 5000 Köln Oxazolinalkansaeuren, deren salze und ester, verfahren zu deren herstellung und diese enthaltende arzneimittel
US4532250A (en) * 1983-11-23 1985-07-30 American Hospital Supply Corporation 5-Heteroarylimidazol-2-ones having cardiotonic activity

Also Published As

Publication number Publication date
JPS62114975A (ja) 1987-05-26
HU197898B (en) 1989-06-28
NO168105C (no) 1992-01-15
AU6493286A (en) 1987-05-21
AU586295B2 (en) 1989-07-06
CA1280754C (en) 1991-02-26
CN86107813A (zh) 1987-07-29
EP0222358A1 (en) 1987-05-20
NZ218237A (en) 1989-08-29
ATE62685T1 (de) 1991-05-15
NO864515D0 (no) 1986-11-12
CN1017150B (zh) 1992-06-24
FI864596A (fi) 1987-05-14
GR3001806T3 (en) 1992-11-23
PH23218A (en) 1989-06-06
KR900000369B1 (ko) 1990-01-25
IL80583A0 (en) 1987-02-27
AR242207A1 (es) 1993-03-31
ES2036518T3 (es) 1993-06-01
PT83734A (en) 1986-12-01
PT83734B (pt) 1988-08-17
FI864596A0 (fi) 1986-11-12
US4698353A (en) 1987-10-06
DE3678795D1 (de) 1991-05-23
EP0222358B1 (en) 1991-04-17
DK540686D0 (da) 1986-11-12
NO864515L (no) 1987-05-14
ZA868503B (en) 1987-06-24
NO168105B (no) 1991-10-07
HUT45032A (en) 1988-05-30
KR870004980A (ko) 1987-06-02

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Legal Events

Date Code Title Description
ATS Application withdrawn