DK516385A - Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter - Google Patents

Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter Download PDF

Info

Publication number
DK516385A
DK516385A DK516385A DK516385A DK516385A DK 516385 A DK516385 A DK 516385A DK 516385 A DK516385 A DK 516385A DK 516385 A DK516385 A DK 516385A DK 516385 A DK516385 A DK 516385A
Authority
DK
Denmark
Prior art keywords
bcelle
celle
determinants
against hepatitis
vaccine against
Prior art date
Application number
DK516385A
Other languages
Danish (da)
English (en)
Other versions
DK516385D0 (da
Inventor
David R Milich
Frank V Chisari
Original Assignee
Scripps Clinic Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/588,122 external-priority patent/US4599230A/en
Priority claimed from US06/587,983 external-priority patent/US4599231A/en
Application filed by Scripps Clinic Res filed Critical Scripps Clinic Res
Publication of DK516385D0 publication Critical patent/DK516385D0/da
Publication of DK516385A publication Critical patent/DK516385A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00Reverse transcribing DNA viruses
    • C12N2730/00011Details
    • C12N2730/10011Hepadnaviridae
    • C12N2730/10111Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Air Bags (AREA)
  • Selective Calling Equipment (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK516385A 1984-03-09 1985-11-08 Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter DK516385A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US06/588,122 US4599230A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
US06/587,983 US4599231A (en) 1984-03-09 1984-03-09 Synthetic hepatitis B virus vaccine including both T cell and B cell determinants
PCT/US1985/000360 WO1985004103A1 (fr) 1984-03-09 1985-03-06 Vaccin synthetique du virus de l'hepatite b comprenant des determinants aussi bien des cellules t que des cellules b

Publications (2)

Publication Number Publication Date
DK516385D0 DK516385D0 (da) 1985-11-08
DK516385A true DK516385A (da) 1985-11-08

Family

ID=27080174

Family Applications (1)

Application Number Title Priority Date Filing Date
DK516385A DK516385A (da) 1984-03-09 1985-11-08 Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter

Country Status (11)

Country Link
EP (1) EP0155146B1 (fr)
AT (1) ATE82135T1 (fr)
AU (2) AU579148B2 (fr)
CA (1) CA1253069A (fr)
DE (1) DE3586801D1 (fr)
DK (1) DK516385A (fr)
FI (1) FI84558C (fr)
IL (3) IL74545A (fr)
NO (1) NO167359C (fr)
NZ (2) NZ227731A (fr)
WO (1) WO1985004103A1 (fr)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2560890B1 (fr) * 1984-03-07 1987-10-16 Grp Genie Genetique Composition utile pour la fabrication de vaccins contenant des particules portant l'antigene de surface du virus de l'hepatite b et le recepteur de l'albumine serique humaine polymerisee, cellules animales capables de produire de telles particules et procede pour leur obtention
AU617292B2 (en) * 1986-06-20 1991-11-28 Scripps Clinic And Research Foundation T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen
US6222020B1 (en) * 1987-01-07 2001-04-24 Imperial Cancer Research Technology Limited Antigens derived from the core protein of the human mammary epithelial mucin
EP0293201A3 (fr) * 1987-05-26 1990-02-28 The Wistar Institute Méthode de vaccination contre le virus de l'hépatite B
WO1988010300A1 (fr) * 1987-06-22 1988-12-29 Medico Labs Ag Immunogenes sous forme de particules peptidiques virales heterologues
WO1989001943A1 (fr) * 1987-09-04 1989-03-09 Whitehead Institute For Biomedical Research Complexes de peptides a stabilite augmentee
EP0491077A1 (fr) * 1990-12-19 1992-06-24 Medeva Holdings B.V. Composition utilisée comme agent thérapeutique contre des maladies hépatiques chroniques
GB9325772D0 (en) * 1993-12-16 1994-02-16 Smithkline Beecham Biolog Novel compounds
JP2000514643A (ja) * 1996-04-18 2000-11-07 アボツト・ラボラトリーズ B型肝炎表面抗原のa―決定基の抗原エピトープ及びその利用法
WO1998012332A1 (fr) 1996-09-17 1998-03-26 Chiron Corporation Compositions et procedes de traitement de maladies intracellulaires
WO1998029442A1 (fr) * 1996-12-30 1998-07-09 Innogenetics N.V. Polypeptides de liaison a l'annexine v derives de l'hbsag et utilisation de ces dernieres
US6881723B1 (en) 1998-11-05 2005-04-19 Powderject Vaccines, Inc. Nucleic acid constructs
ES2330904B1 (es) 2005-09-21 2010-09-23 Fundacio Centre De Recerca En Sanitat Animal Polinucleotidos de haemophilus parasuis y su uso.
CA2926004A1 (fr) 2006-08-11 2008-02-14 Life Sciences Research Partners Vzw Peptides immunogeniques et leurs utilisations pour les troubles allergiques et autoimmuns
WO2009101205A2 (fr) 2008-02-14 2009-08-20 Life Sciences Research Partners Vzw Lutte par voie immunogène contre les tumeurs et cellules tumorales
ES2637812T3 (es) 2008-02-14 2017-10-17 Life Sciences Research Partners Vzw Inmunoterapia dirigida a patógenos intracelulares
EP3763729B1 (fr) 2010-11-25 2022-07-06 Imcyse SA Peptides immunogènes destinés à la prévention et/ou au traitement de maladies infectieuses, de maladies auto-immunes, de réponses immunitaires aux allofacteurs, de maladies allergiques, de tumeurs, du rejet de greffe, et des réponses immunitaires dirigées contre des vecteurs viraux utilisés en thérapie génique ou en vaccination génique
GB201201511D0 (en) 2012-01-30 2012-03-14 Univ Leuven Kath Modified epitopes for boosting CD4+ T-cell responses
EP2860188B1 (fr) * 2012-06-11 2020-10-21 Xiamen University Polypeptides et anticorps pour le traitement d'une infection par le vbh et maladies associées
GB201309469D0 (en) 2013-05-28 2013-07-10 Imcyse Sa Detection of CD4+ T lymphocytes
US10729791B2 (en) 2015-05-18 2020-08-04 Imcyse Sa Animal models for evaluating pharmaceutical compounds
EP3352782B1 (fr) 2015-09-25 2021-03-31 ImCyse SA Composés et procédés améliorés permettant de supprimer des réponses immunitaires à des agents thérapeutiques
KR20220132023A (ko) 2016-04-19 2022-09-29 임시스 에스에이 신규 면역원성 CD1d 결합 펩티드
CN108456686B (zh) 2017-02-17 2021-03-05 厦门大学 一种用于展示目的多肽的多肽载体及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA792485B (en) * 1978-06-07 1980-06-25 New York Blood Center Inc Vaccine for active immunization containing hepatitis b surface and/or e-antigens
FR2480779B2 (fr) * 1979-08-30 1986-07-18 Anvar Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur
JP2530801B2 (ja) * 1978-12-22 1996-09-04 バイオゲン インコーポレイテッド 組換えdna分子
US4415491A (en) * 1980-01-14 1983-11-15 The Regents Of The University Of California Synthetic vaccine peptide epitomes of hepatitis B surface antigen
IL63224A (en) * 1980-07-17 1985-05-31 Scripps Clinic Res Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom
IL61904A (en) * 1981-01-13 1985-07-31 Yeda Res & Dev Synthetic vaccine against influenza virus infections comprising a synthetic peptide and process for producing same
DE3275998D1 (en) * 1981-12-22 1987-05-14 Baylor College Medicine Immunological composition and method for hepatitis b virus
US4483793A (en) * 1982-10-04 1984-11-20 The Regents Of The University Of California Dimeric oligopeptides as heptenic epitopic sites for hepatitis
JPS5974985A (ja) * 1982-10-19 1984-04-27 Takeda Chem Ind Ltd 新規dna
NZ207394A (en) * 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids

Also Published As

Publication number Publication date
AU4115985A (en) 1985-10-11
ATE82135T1 (de) 1992-11-15
IL90035A0 (en) 1989-12-15
AU2682388A (en) 1989-05-25
AU579148B2 (en) 1988-11-17
FI854396A (fi) 1985-11-07
EP0155146A3 (en) 1988-01-20
FI854396A0 (fi) 1985-11-07
IL90035A (en) 1990-11-05
NO167359B (no) 1991-07-22
IL74545A (en) 1990-11-05
NO854460L (no) 1986-01-08
DK516385D0 (da) 1985-11-08
FI84558C (fi) 1991-12-27
NO167359C (no) 1991-10-30
CA1253069A (fr) 1989-04-25
FI84558B (fi) 1991-09-13
DE3586801D1 (de) 1992-12-17
NZ227731A (en) 1990-07-26
EP0155146B1 (fr) 1992-11-11
WO1985004103A1 (fr) 1985-09-26
AU623106B2 (en) 1992-05-07
IL74545A0 (en) 1985-06-30
EP0155146A2 (fr) 1985-09-18
NZ211356A (en) 1990-07-26

Similar Documents

Publication Publication Date Title
DK516385A (da) Syntetisk vaccine mod hepatitis b virus indeholdende baade t celle og bcelle determinanter
LU91498I2 (fr) Etanercept et ses dérivés pharmaceutiquement acceptables.
ES2097878T3 (es) Fijacion de p53 sobre el adn mediante una secuencia especifica.
ATE98493T1 (de) Verwendung des rotavirus-nukleokapsid-vp6proteins in impfstoffzusammensetzungen.
DE59504181D1 (de) Von einem Retrovirus aus der HIV-Gruppe abgeleitete Peptide und deren Verwendung
FI863041A (fi) Fusionsprotein, foerfarande foer deras framstaellning och deras anvaendning.
ES555124A0 (es) Procedimiento de preparar particulas que contienen secuencias de aminoacidos y que tienen propiedades inmunogenas
DK235289D0 (da) Ekspression af hapatitis b s- og praes2-proteiner i methylotrophe gaerarter
DE69230671D1 (de) Impfstoffe gegen actinobacillus pleuropneumonie
FI902569A0 (fi) Producering av till gonorre anslutande pi-proteiner och vaccin.
EA200100395A1 (ru) Фармацевтическая композиция, содержащая фрагменты днк, кодирующей антигенный белок, обладающая противоопухолевым действием
DK0584118T3 (da) Nyt konjugat, bestående af et glycoprotein og en nucleinsyrebindende substans
EP0485347A3 (en) Recombinant hepatitis delta antigen, process for the purification and use thereof
IS3511A7 (is) Fjölpeptíð framleidd með aðferðum líftækninnar, kjarnsýrur sem samsvara þeim, og notkun fjölpeptíðanna sem bóluefnis gegn VHS veiru í fiski
SU1380209A1 (ru) РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК PUR 291-HAV 22, КОДИРУЮЩАЯ СИНТЕЗ ГИБРИДНОГО ПОЛИПЕПТИДА АНТИГЕННЫХ ДЕТЕРМИНАНТ ВИРУСА ГЕПАТИТА А С β -ГАЛАКТОЗИДАЗОЙ
ES8801127A1 (es) Un procedimiento para preparar una vacuna auto antigena en forma de virus modificado de la viruela vacuna.
ES8801949A1 (es) Un procedimiento para la preparacion de un vector de expresion que comprende un gen que codifica una proteina envolvente de un virus de sida
DK381787A (da) Rensede antigener med vaccineegenskaber mod b. pertussis, midler, navnlig rekombinant-dna, til fremstilling deraf og vaccinepraeparater indeholdende disse

Legal Events

Date Code Title Description
AHB Application shelved due to non-payment