DK515184D0 - Fremgangsmaade til fremstilling af 2-brom-8-ergolinylforbindelser - Google Patents
Fremgangsmaade til fremstilling af 2-brom-8-ergolinylforbindelserInfo
- Publication number
- DK515184D0 DK515184D0 DK515184A DK515184A DK515184D0 DK 515184 D0 DK515184 D0 DK 515184D0 DK 515184 A DK515184 A DK 515184A DK 515184 A DK515184 A DK 515184A DK 515184 D0 DK515184 D0 DK 515184D0
- Authority
- DK
- Denmark
- Prior art keywords
- bromo
- preparing
- procedure
- see diagramm
- ergolinyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/10—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hetero atoms directly attached in position 8
- C07D457/12—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C07D519/02—Ergot alkaloids of the cyclic peptide type
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3340025A DE3340025C2 (de) | 1983-11-03 | 1983-11-03 | Verfahren zur Herstellung von 2-Brom-8-ergolinyl-Verbindungen |
| DE3340025 | 1983-11-03 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK515184D0 true DK515184D0 (da) | 1984-10-29 |
| DK515184A DK515184A (da) | 1985-05-04 |
| DK163583B DK163583B (da) | 1992-03-16 |
| DK163583C DK163583C (da) | 1992-08-24 |
Family
ID=6213531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK515184A DK163583C (da) | 1983-11-03 | 1984-10-29 | Fremgangsmaade til fremstilling af 2-brom-8-ergolinylforbindelser |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4970314A (da) |
| EP (1) | EP0141387B1 (da) |
| JP (1) | JPS60115580A (da) |
| AT (1) | ATE42103T1 (da) |
| CA (1) | CA1253489A (da) |
| CS (1) | CS247089B2 (da) |
| DE (2) | DE3340025C2 (da) |
| DK (1) | DK163583C (da) |
| HU (1) | HU198714B (da) |
| IE (1) | IE57909B1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3101535A1 (de) * | 1981-01-14 | 1982-08-12 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue (2-halogen-ergolinyl)-n'.n'-diethyl-harnstoffderivate, verfahren zu ihrer herstellung und deren verwendung als arzneimittel |
| DE3303616A1 (de) * | 1982-02-12 | 1983-08-25 | Sandoz-Patent-GmbH, 7850 Lörrach | Mutterkornalkaloide, verfahren zu deren herstellung sowie diese verbindungen enthaltende pharmazeutische zubereitungen |
| DD238051A1 (de) * | 1985-06-10 | 1986-08-06 | Dresden Arzneimittel | Verfahren zur herstellung neuer lysergsaeureamide |
| HU193317B (en) * | 1985-06-12 | 1987-09-28 | Richter Gedeon Vegyeszet | Process for producing 2-bromo-alpha-ergochristin |
| US5441961A (en) * | 1992-08-27 | 1995-08-15 | Eli Lilly And Company | Substituted cyclo or bicycloalkylamides of (8β)-6-(substituted) ergolines |
| CA2895829A1 (en) * | 2012-12-21 | 2014-06-26 | Map Pharmaceuticals, Inc. | Novel methysergide derivatives |
| US9676776B2 (en) | 2015-01-20 | 2017-06-13 | Xoc Pharmaceuticals, Inc. | Isoergoline compounds and uses thereof |
| CN107428745A (zh) | 2015-01-20 | 2017-12-01 | Xoc制药股份有限公司 | 麦角灵化合物及其用途 |
| AU2018275873A1 (en) | 2017-06-01 | 2019-12-19 | Xoc Pharmaceuticals, Inc. | Ergoline derivatives for use in medicine |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH507249A (de) * | 1968-05-31 | 1971-05-15 | Sandoz Ag | Verfahren zur Herstellung von 2-Brom-a-ergokryptin |
| DE2330912C3 (de) * | 1972-06-22 | 1979-01-11 | Societa Farmaceutici Italia S.P.A., Mailand (Italien) | Verfahren zur Herstellung von Bromergolinverbindungen |
| YU216177A (en) * | 1977-09-09 | 1984-02-29 | Rudolf Rucman | Process for preparing 2-bromo ergosine |
| US4166182A (en) * | 1978-02-08 | 1979-08-28 | Eli Lilly And Company | 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds |
| YU40046B (en) * | 1978-09-04 | 1985-06-30 | Lek Tovarna Farmacevtskih | Process for preparing 2-bromo-9,10-dihydroergosine |
| HU180929B (en) * | 1979-08-13 | 1983-05-30 | Richter Gedeon Vegyeszet | Process for producing new bromo-vincamone derivatives |
| US4609731A (en) * | 1979-10-10 | 1986-09-02 | Sandoz Ltd. | Process for brominating ergot alkaloids |
| US4352909A (en) * | 1980-08-20 | 1982-10-05 | Ferro Corporation | Process for the bromination of polystyrenes |
-
1983
- 1983-11-03 DE DE3340025A patent/DE3340025C2/de not_active Expired
-
1984
- 1984-10-25 IE IE2743/84A patent/IE57909B1/en not_active IP Right Cessation
- 1984-10-26 EP EP84112913A patent/EP0141387B1/de not_active Expired
- 1984-10-26 AT AT84112913T patent/ATE42103T1/de not_active IP Right Cessation
- 1984-10-26 DE DE8484112913T patent/DE3477666D1/de not_active Expired
- 1984-10-29 DK DK515184A patent/DK163583C/da active
- 1984-11-01 CA CA000466871A patent/CA1253489A/en not_active Expired
- 1984-11-01 CS CS848310A patent/CS247089B2/cs unknown
- 1984-11-01 JP JP59229050A patent/JPS60115580A/ja active Granted
- 1984-11-02 HU HU844078A patent/HU198714B/hu not_active IP Right Cessation
- 1984-11-05 US US06/668,344 patent/US4970314A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE3340025C2 (de) | 1986-01-09 |
| DK163583C (da) | 1992-08-24 |
| IE842743L (en) | 1985-05-03 |
| IE57909B1 (en) | 1993-05-05 |
| US4970314A (en) | 1990-11-13 |
| EP0141387A1 (de) | 1985-05-15 |
| DK163583B (da) | 1992-03-16 |
| DK515184A (da) | 1985-05-04 |
| HUT35672A (en) | 1985-07-29 |
| HU198714B (en) | 1989-11-28 |
| CA1253489A (en) | 1989-05-02 |
| DE3340025A1 (de) | 1985-05-23 |
| DE3477666D1 (en) | 1989-05-18 |
| JPH0556349B2 (da) | 1993-08-19 |
| EP0141387B1 (de) | 1989-04-12 |
| CS247089B2 (en) | 1986-11-13 |
| JPS60115580A (ja) | 1985-06-22 |
| ATE42103T1 (de) | 1989-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK399082A (da) | Fremgangsmaade til fremstilling af carbonhydrider | |
| DK163583C (da) | Fremgangsmaade til fremstilling af 2-brom-8-ergolinylforbindelser | |
| DK542785A (da) | Fremgangsmaade til fremstilling af 7-halogen-7-deoxylincomycin eller dermed analoge forbindelser | |
| DE3866120D1 (de) | Knotenelement zum gebrauch beim enrichten einer geodaetischen struktur. | |
| MX9303713A (es) | Proceso estereoselectivo para preparar un derivadoribofuranosilo enriquecido con alfa anomero. | |
| AR241531A1 (es) | Un procedimiento para la preparacion derivados de 2-indolinona, y sus sales farmaceuticamente aceptables. | |
| EP0211578A3 (en) | N-fluoro-n-perfluoromethyl sulfonamides | |
| DK354987A (da) | Fremgangsmaade til fremstilling af floursulfonamider | |
| DK157755C (da) | Fremgangsmaade til fremstilling af beta-carbolinderivater | |
| DK160489C (da) | Fremgangsmaade til fremstilling af 2,3-difluorpyridinforbindelser | |
| DK159083D0 (da) | Fremgangsmade til fremstilling af n-(1,3-dithiolan-2-yliden)-aniliner | |
| DE3366279D1 (de) | Substituted tetrahydropyridazino(1,6-a)benzimidazoles | |
| ATE21902T1 (de) | 6-substituierte tetrahydroimidazo(2,1a)phthalazine. | |
| DK291187D0 (da) | Fremgangsmaade til styring af svejseforloebet ved tilvejebringelse af en muffeforbindelse til varmeisolerede ledningsroer | |
| ES532983A0 (es) | Procedimiento para la fabricacion de los derivados del acido bicilo (3.2.1) octan carboxilico-3 | |
| SE8107021L (sv) | Nytt forfarande for framstellning av imidazo(4,5-b)-pyridiner och -pyrimidiner | |
| ES534532A0 (es) | Un procedimiento para preparar derivados de benzamida. | |
| DK344083A (da) | Fremgangsmaade til fremstilling af 3a-(substitueret phenyl)-3a,4,7,7a-tetrahydro-4,7-methanoisoindoliner | |
| DK389484D0 (da) | Fremgangsmaade til fremstilling af 2,3-dihydrobenzopyranonderivater | |
| DK508984D0 (da) | Fremgangsmaade til dekomponering af n-oxydderivater til dannelse afolefiniske forbindelser i hoejt udbytte | |
| DK157871C (da) | Fremgangsmaade til fremstilling af 1,3-dihydro-6-(1-hydroxy-2-dimethylaminomethyl-allyl)-7-hydroxy-furo-(3,4-c)-pyridin-derivater | |
| SU636402A1 (ru) | Безболтовое соединение элементов податливой крепи | |
| ATE32340T1 (de) | Substituierte tetrahydrotetrazolo(5,1a)phthalazine. | |
| NO153852C (no) | Fremgangsmaate for fremstilling av selektivt bromerte organiske forbindelser. | |
| DK476179A (da) | Aggregat til pladsbesparende ophaengning af genstande saasom cykler ringe haveredskaber eller lignende |