DK50987A - Polypeptid med plasminogenaktivatorvirkning - Google Patents

Polypeptid med plasminogenaktivatorvirkning

Info

Publication number
DK50987A
DK50987A DK050987A DK50987A DK50987A DK 50987 A DK50987 A DK 50987A DK 050987 A DK050987 A DK 050987A DK 50987 A DK50987 A DK 50987A DK 50987 A DK50987 A DK 50987A
Authority
DK
Denmark
Prior art keywords
polypeptide
plasminogen activator
activator activity
activity
plasminogen
Prior art date
Application number
DK050987A
Other languages
English (en)
Other versions
DK50987D0 (da
DK175604B1 (da
Inventor
Michito Tagawa
Masakatsu Wada
Masayuki Yamada
Midori Yokoyama
Naganori Numao
Original Assignee
Sagami Chem Res
Central Glass Co Ltd
Hodogaya Chemical Co Ltd
Nippon Soda Co
Nissan Chemical Ind Ltd
Toyo Soda Mfg Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chem Res, Central Glass Co Ltd, Hodogaya Chemical Co Ltd, Nippon Soda Co, Nissan Chemical Ind Ltd, Toyo Soda Mfg Co Ltd filed Critical Sagami Chem Res
Publication of DK50987D0 publication Critical patent/DK50987D0/da
Publication of DK50987A publication Critical patent/DK50987A/da
Application granted granted Critical
Publication of DK175604B1 publication Critical patent/DK175604B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK198700509A 1986-01-31 1987-01-30 Hybridt plasminogenaktivatorlignende polypeptid DK175604B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP1773486 1986-01-31
JP1773486 1986-01-31

Publications (3)

Publication Number Publication Date
DK50987D0 DK50987D0 (da) 1987-01-30
DK50987A true DK50987A (da) 1987-08-01
DK175604B1 DK175604B1 (da) 2004-12-20

Family

ID=11951975

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198700509A DK175604B1 (da) 1986-01-31 1987-01-30 Hybridt plasminogenaktivatorlignende polypeptid

Country Status (7)

Country Link
EP (1) EP0231883B1 (da)
JP (1) JP2589687B2 (da)
DE (1) DE3781420T2 (da)
DK (1) DK175604B1 (da)
ES (1) ES2043610T3 (da)
SU (1) SU1732814A3 (da)
WO (1) WO1987004720A1 (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4916071A (en) * 1985-08-14 1990-04-10 American Home Products Corporation Poly-kringle plasminogen activator
FI100106B (fi) * 1986-12-05 1997-09-30 Novartis Ag Menetelmä plasminogeenin yksisäikeisen yhdistelmäaktivaattorin valmist amiseksi
US5580559A (en) * 1986-12-05 1996-12-03 Ciba-Geigy Corporation Hybrid plasminogen activator
US5242819A (en) * 1986-12-05 1993-09-07 Ciba-Geigy Corporation DNA molecules encoding hybrid proteins of tissue plasminogen activator and urokinase
ZA879286B (en) * 1986-12-16 1988-10-26 Smith Kline Rit New plasminogen activators
WO1988005081A2 (en) * 1986-12-30 1988-07-14 Cetus Corporation Novel plasminogen activator
NL8700013A (nl) * 1987-01-06 1988-08-01 Leuven Res & Dev Vzw Hybride plasminogeenactivatoren met verbeterde trombolytische eigenschappen en geneesmiddelen die deze plasminogeenactivatoren bevatten.
NL8701021A (nl) * 1987-04-29 1988-11-16 Stichting Centraal Lab Humane t-pa(u-pa) substitutie-mutant eiwitten, daarvoor coderend recombinant dna, getransfecteerde gastheercellen, bereiding van de mutant eiwitten, en farmaceutische preparaten.
JP2561122B2 (ja) * 1988-04-13 1996-12-04 寳酒造株式会社 機能性ポリペプチド
JPH07143877A (ja) * 1993-10-01 1995-06-06 Sumitomo Pharmaceut Co Ltd 新規なｔ−ＰＡ類似体
EP4129334A1 (en) * 2020-03-31 2023-02-08 National Cancer Center Fusion protein suitable for dissolving fibrin clot, and pharmaceutical composition containing said fusion protein
WO2023195535A1 (ja) * 2022-04-08 2023-10-12 株式会社凜研究所 フィブリンに結合する抗体および当該抗体を含むフィブリン溶解性タンパク質および当該タンパク質を含む医薬製剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
GB8314362D0 (en) * 1983-05-24 1983-06-29 Celltech Ltd Polypeptide and protein products
JPS60136520A (ja) * 1983-12-23 1985-07-20 Otsuka Pharmaceut Co Ltd フイブリン吸着性ウロキナ−ゼ複合体
GB8334498D0 (en) * 1983-12-24 1984-02-01 Beecham Group Plc Compounds

Also Published As

Publication number Publication date
DK50987D0 (da) 1987-01-30
ES2043610T3 (es) 1994-01-01
DE3781420T2 (de) 1993-02-25
EP0231883A1 (en) 1987-08-12
JP2589687B2 (ja) 1997-03-12
WO1987004720A1 (en) 1987-08-13
DE3781420D1 (de) 1992-10-08
DK175604B1 (da) 2004-12-20
JPS62272975A (ja) 1987-11-27
EP0231883B1 (en) 1992-09-02
SU1732814A3 (ru) 1992-05-07

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Legal Events

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