DK444789A - Tricykliske forbindelser - Google Patents

Tricykliske forbindelser

Info

Publication number
DK444789A
DK444789A DK444789A DK444789A DK444789A DK 444789 A DK444789 A DK 444789A DK 444789 A DK444789 A DK 444789A DK 444789 A DK444789 A DK 444789A DK 444789 A DK444789 A DK 444789A
Authority
DK
Denmark
Prior art keywords
tricyclic
relations
tricyclic relations
Prior art date
Application number
DK444789A
Other languages
Danish (da)
English (en)
Other versions
DK444789D0 (da
Inventor
Yoshinari Sato
Teruaki Matuo
Takatomo Ogahara
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888821257A external-priority patent/GB8821257D0/en
Priority claimed from GB888829265A external-priority patent/GB8829265D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of DK444789D0 publication Critical patent/DK444789D0/da
Publication of DK444789A publication Critical patent/DK444789A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/06—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Nutrition Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK444789A 1988-09-09 1989-09-08 Tricykliske forbindelser DK444789A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888821257A GB8821257D0 (en) 1988-09-09 1988-09-09 Tricyclic compounds
GB888829265A GB8829265D0 (en) 1988-12-15 1988-12-15 Tricyclic compounds

Publications (2)

Publication Number Publication Date
DK444789D0 DK444789D0 (da) 1989-09-08
DK444789A true DK444789A (da) 1990-03-10

Family

ID=26294376

Family Applications (1)

Application Number Title Priority Date Filing Date
DK444789A DK444789A (da) 1988-09-09 1989-09-08 Tricykliske forbindelser

Country Status (18)

Country Link
US (2) US4981847A (fr)
EP (1) EP0360079B1 (fr)
JP (3) JPH0665673B2 (fr)
KR (1) KR900004737A (fr)
CN (1) CN1022187C (fr)
AU (1) AU628370B2 (fr)
DE (1) DE68912858T2 (fr)
DK (1) DK444789A (fr)
ES (1) ES2061848T3 (fr)
FI (1) FI92401C (fr)
HK (1) HK101996A (fr)
HU (2) HUT54152A (fr)
IE (1) IE62916B1 (fr)
IL (1) IL91361A (fr)
NO (1) NO171913C (fr)
PH (1) PH27358A (fr)
PT (1) PT91664B (fr)
RU (1) RU2007406C1 (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630440B1 (fr) * 1988-04-25 1991-09-20 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique
IL91361A (en) * 1988-09-09 1994-10-07 Fujisawa Pharmaceutical Co Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them
US5248679A (en) * 1988-09-09 1993-09-28 Fujisawa Pharmaceutical Co., Ltd. Tricyclic compounds
PH26955A (en) * 1989-03-08 1992-12-03 Kali Chemie Pharma Gmbh Novel 1,7-fused 1H-indole-2-carboxylic acid N-(1,4-benzodiazepin-3-YL) amides
FR2652352A1 (fr) * 1989-09-28 1991-03-29 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique.
GB9018601D0 (en) * 1990-08-24 1990-10-10 Fujisawa Pharmaceutical Co Tricyclic compounds
CA2056809A1 (fr) * 1990-12-07 1992-06-08 Mark G. Bock Analogues de la benzodiazepine
EP0572235A3 (en) * 1992-05-28 1994-06-01 Tanabe Seiyaku Co Beta-carboline derivatives with anticholecystoquinine activity
GB2271354A (en) * 1992-10-07 1994-04-13 Merck Sharp & Dohme Tricyclic derivatives of benzodiazepines
AU6045994A (en) * 1993-03-03 1994-09-26 Fujisawa Pharmaceutical Co., Ltd. Optical isomerization inhibitor
DE69429584T2 (de) * 1993-11-26 2002-08-08 Tanabe Seiyaku Co 2-oxoindolin-derivate als cholecystokinin rezeptor antagonisten
JPH10504545A (ja) * 1994-07-29 1998-05-06 藤沢薬品工業株式会社 ベンゾジアゼピン誘導体
WO1996006617A1 (fr) * 1994-08-30 1996-03-07 Fujisawa Pharmaceutical Co., Ltd. Preparation de liposomes
FR2725719B1 (fr) * 1994-10-14 1996-12-06 Jouveinal Inst Rech Diazepino-indoles inhibiteurs de phosphodiesterases iv
US5716958A (en) 1994-10-27 1998-02-10 Tobishi Pharmaceutical Co., Ltd. Amino acid derivative having anti-CCK activity
AUPO284396A0 (en) 1996-10-08 1996-10-31 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
FR2776660B1 (fr) * 1998-03-27 2000-05-12 Parke Davis Diazepino-indoles de phosphodiesterases iv
JP2015534554A (ja) 2012-09-21 2015-12-03 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ アルキル，フルオロアルキル−１，４−ベンゾジアゼピノン化合物
CN104822665A (zh) 2012-09-21 2015-08-05 百时美施贵宝公司 用作Notch抑制剂的氟烷基和氟环烷基1,4-苯并二氮杂*酮化合物
EP2897938B1 (fr) 2012-09-21 2017-03-15 Bristol-Myers Squibb Company Composés fluoroalkyl benzodiazépinones
US9133139B2 (en) 2012-09-21 2015-09-15 Bristol-Myers Squibb Company Fluoroalkyl-1,4-benzodiazepinone compounds
JP2015534553A (ja) 2012-09-21 2015-12-03 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ 置換１，５−ベンゾジアゼピノン化合物
EP2897960B1 (fr) 2012-09-21 2016-08-03 Bristol-Myers Squibb Company Composés hétérocycliques tricycliques utilisables en tant qu'inhibiteurs du récepteur notch
JP2015533811A (ja) 2012-09-21 2015-11-26 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ Ｎ−置換ビス（フルオロアルキル）１，４−ベンゾジアゼピノン化合物
EP2897941B1 (fr) 2012-09-21 2016-09-07 Bristol-Myers Squibb Company Promédicaments de composés 1,4-benzodiazépinones
US9492469B2 (en) 2013-04-04 2016-11-15 Bristol-Myers Squibb Company Combination therapy for the treatment of proliferative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3651083A (en) * 1969-11-03 1972-03-21 Upjohn Co Tetra- and hexahydro-phenylpyrrolo benzodiazepines and intermediates
US3794646A (en) * 1970-04-14 1974-02-26 Robins Co Inc A H 5,7-disubstituted-1,9-tetramethylene-1,4-benzodiazepin-2-ones
AU2733371A (en) * 1970-04-14 1972-10-12 A. H. Robins Company, Incorporated 5, 7-DISUBSTITUTED-l, 9-ALKYLENE-l, 4-BENZODIAZEPIN-2 ONES
CA1332410C (fr) * 1984-06-26 1994-10-11 Roger M. Freidinger Analogues de benzodiazepines
US4735941A (en) * 1986-12-23 1988-04-05 Merck & Co., Inc. 1,4-benzodiazepines with 5- and 6-membered heterocyclic rings, useful as gastrointestinal and CNS agents
FR2630440B1 (fr) * 1988-04-25 1991-09-20 Jouveinal Sa Benzodiazepines, leur procede et intermediaires de preparation et leurs applications en therapeutique
IL91361A (en) * 1988-09-09 1994-10-07 Fujisawa Pharmaceutical Co Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
DE68912858D1 (de) 1994-03-17
DK444789D0 (da) 1989-09-08
PT91664B (pt) 1995-05-31
HUT54152A (en) 1991-01-28
HU211264A9 (en) 1995-11-28
JPH0741480A (ja) 1995-02-10
US4981847A (en) 1991-01-01
PT91664A (pt) 1990-03-30
NO893616L (no) 1990-03-12
FI92401B (fi) 1994-07-29
JPH0748373A (ja) 1995-02-21
AU4025789A (en) 1990-03-15
FI894169A0 (fi) 1989-09-05
JPH02111774A (ja) 1990-04-24
NO171913C (no) 1993-05-19
EP0360079B1 (fr) 1994-02-02
KR900004737A (ko) 1990-04-12
IL91361A0 (en) 1990-03-19
JPH0665673B2 (ja) 1994-08-24
US5155101A (en) 1992-10-13
IE892840L (en) 1990-03-09
RU2007406C1 (ru) 1994-02-15
FI92401C (fi) 1994-11-10
HK101996A (en) 1996-06-21
CN1022187C (zh) 1993-09-22
CN1040981A (zh) 1990-04-04
NO893616D0 (no) 1989-09-08
EP0360079A1 (fr) 1990-03-28
JP2848230B2 (ja) 1999-01-20
PH27358A (en) 1993-06-21
FI894169A (fi) 1990-03-10
IL91361A (en) 1994-10-07
DE68912858T2 (de) 1994-06-01
AU628370B2 (en) 1992-09-17
IE62916B1 (en) 1995-03-08
ES2061848T3 (es) 1994-12-16
NO171913B (no) 1993-02-08

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment