DE69429584T2 - 2-oxoindolin-derivate als cholecystokinin rezeptor antagonisten - Google Patents
2-oxoindolin-derivate als cholecystokinin rezeptor antagonistenInfo
- Publication number
- DE69429584T2 DE69429584T2 DE69429584T DE69429584T DE69429584T2 DE 69429584 T2 DE69429584 T2 DE 69429584T2 DE 69429584 T DE69429584 T DE 69429584T DE 69429584 T DE69429584 T DE 69429584T DE 69429584 T2 DE69429584 T2 DE 69429584T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- heterocyclic group
- substituted
- chem
- unsubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/40—Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/06—Peri-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP29618393 | 1993-11-26 | ||
PCT/JP1994/001990 WO1995014668A1 (fr) | 1993-11-26 | 1994-11-25 | Derive de 2-oxoindoline |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69429584D1 DE69429584D1 (en) | 2002-02-07 |
DE69429584T2 true DE69429584T2 (de) | 2002-08-08 |
Family
ID=17830244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69429584T Expired - Fee Related DE69429584T2 (de) | 1993-11-26 | 1994-11-25 | 2-oxoindolin-derivate als cholecystokinin rezeptor antagonisten |
Country Status (11)
Country | Link |
---|---|
US (1) | US5807883A (de) |
EP (1) | EP0731091B1 (de) |
KR (1) | KR100235161B1 (de) |
CN (1) | CN1069314C (de) |
AT (1) | ATE211464T1 (de) |
CA (1) | CA2177147C (de) |
DE (1) | DE69429584T2 (de) |
DK (1) | DK0731091T3 (de) |
ES (1) | ES2173163T3 (de) |
PT (1) | PT731091E (de) |
WO (1) | WO1995014668A1 (de) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI314041B (en) * | 2002-10-21 | 2009-09-01 | Sankyo Agro Co Ltd | Quinolyl-3-carboxamide compound |
WO2004103310A2 (en) * | 2003-05-20 | 2004-12-02 | New England Medical Center Hospitals, Inc. | Methods and compositions for the treatment of metabolic disorders |
US8563567B2 (en) | 2009-12-30 | 2013-10-22 | Arqule, Inc. | Substituted heterocyclic compounds |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0304223A3 (de) * | 1987-08-17 | 1990-10-24 | Merck & Co. Inc. | Beta-Carboline als Cholecystokinin und Gastrin-Antagonist |
WO1989005812A1 (en) * | 1987-12-22 | 1989-06-29 | Yoshitomi Pharmaceutical Industries, Ltd. | Thienodiazepine compounds and their medicinal use |
DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
IL91361A (en) * | 1988-09-09 | 1994-10-07 | Fujisawa Pharmaceutical Co | Benzodiazepinone compounds [4,1] connected via positions 1 and 9 and carrying two transducers, processes for their preparation and pharmaceutical preparations containing them |
JP2610771B2 (ja) * | 1992-05-28 | 1997-05-14 | 田辺製薬株式会社 | β−カルボリン誘導体 |
EP0572235A3 (en) * | 1992-05-28 | 1994-06-01 | Tanabe Seiyaku Co | Beta-carboline derivatives with anticholecystoquinine activity |
TW281669B (de) * | 1993-02-17 | 1996-07-21 | Chugai Pharmaceutical Co Ltd |
-
1994
- 1994-11-25 DE DE69429584T patent/DE69429584T2/de not_active Expired - Fee Related
- 1994-11-25 CA CA002177147A patent/CA2177147C/en not_active Expired - Fee Related
- 1994-11-25 ES ES95901596T patent/ES2173163T3/es not_active Expired - Lifetime
- 1994-11-25 PT PT95901596T patent/PT731091E/pt unknown
- 1994-11-25 AT AT95901596T patent/ATE211464T1/de not_active IP Right Cessation
- 1994-11-25 WO PCT/JP1994/001990 patent/WO1995014668A1/ja active IP Right Grant
- 1994-11-25 DK DK95901596T patent/DK0731091T3/da active
- 1994-11-25 KR KR1019960702757A patent/KR100235161B1/ko not_active IP Right Cessation
- 1994-11-25 US US08/648,191 patent/US5807883A/en not_active Expired - Fee Related
- 1994-11-25 EP EP95901596A patent/EP0731091B1/de not_active Expired - Lifetime
- 1994-11-25 CN CN94194288A patent/CN1069314C/zh not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CA2177147C (en) | 2001-10-09 |
EP0731091A4 (de) | 1997-09-17 |
DK0731091T3 (da) | 2002-04-15 |
EP0731091B1 (de) | 2002-01-02 |
CA2177147A1 (en) | 1995-06-01 |
CN1069314C (zh) | 2001-08-08 |
ATE211464T1 (de) | 2002-01-15 |
PT731091E (pt) | 2002-05-31 |
WO1995014668A1 (fr) | 1995-06-01 |
ES2173163T3 (es) | 2002-10-16 |
CN1136310A (zh) | 1996-11-20 |
US5807883A (en) | 1998-09-15 |
DE69429584D1 (en) | 2002-02-07 |
KR100235161B1 (ko) | 2001-11-22 |
EP0731091A1 (de) | 1996-09-11 |
KR960705778A (ko) | 1996-11-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69628276D1 (de) | Zubereitung von xanthinderivaten als feste dispersion | |
FI941417A0 (fi) | Typpipitoiset heterosykliset yhdisteet | |
FI933213A (fi) | Nya piperidinderivat av bensimidazolin | |
DE69327944D1 (de) | Thiazolidindione-Derivate, ihre Herstellung und Verwendung | |
ATE125808T1 (de) | Indolederivate und ihre verwendung als serotonin- antagoniste. | |
AU9281198A (en) | Benzofuran derivatives | |
ATE122344T1 (de) | Naphthyloxazolidon-derivate. | |
NO953052D0 (no) | Nye pyrrolokarbazoler | |
ATE211464T1 (de) | 2-oxoindolin-derivate als cholecystokinin rezeptor antagonisten | |
DE69911176D1 (de) | Spiropiperidin-derivate | |
HU9602534D0 (en) | Use of biphenyl methyl imidazole derivatives for producing pharmaceutical compositions having ocular tension derpessant activity | |
ES2149180T3 (es) | Derivado de pirazolotiazolopirimidina. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |