DK434587A - Heparinderivater, farmaceutisk praeparat, der indeholder dem og anvendelsen af derivaterne - Google Patents

Heparinderivater, farmaceutisk praeparat, der indeholder dem og anvendelsen af derivaterne

Info

Publication number
DK434587A
DK434587A DK434587A DK434587A DK434587A DK 434587 A DK434587 A DK 434587A DK 434587 A DK434587 A DK 434587A DK 434587 A DK434587 A DK 434587A DK 434587 A DK434587 A DK 434587A
Authority
DK
Denmark
Prior art keywords
derivatives
heparin
activity
molecular weight
low molecular
Prior art date
Application number
DK434587A
Other languages
English (en)
Other versions
DK175087B1 (da
DK434587D0 (da
Inventor
Kevin Michael Foley
Charles Campbell Griffin
Original Assignee
Univ Miami
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/898,127 external-priority patent/US4745108A/en
Priority claimed from US06/898,431 external-priority patent/US4942156A/en
Priority claimed from US06/898,124 external-priority patent/US4745107A/en
Priority claimed from US06/898,436 external-priority patent/US4745106A/en
Priority claimed from US06/898,130 external-priority patent/US4745105A/en
Application filed by Univ Miami filed Critical Univ Miami
Publication of DK434587D0 publication Critical patent/DK434587D0/da
Publication of DK434587A publication Critical patent/DK434587A/da
Application granted granted Critical
Publication of DK175087B1 publication Critical patent/DK175087B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
    • C08B37/0075—Heparin; Heparan sulfate; Derivatives thereof, e.g. heparosan; Purification or extraction methods thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
DK198704345A 1986-08-20 1987-08-20 Alkanoylestere af heparin, farmaceutisk præparat, der indeholder dem og anvendelse deraf DK175087B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
US89843686 1986-08-20
US06/898,127 US4745108A (en) 1986-08-20 1986-08-20 Heparin derivatives having decreased anti-Xa specificity
US89812786 1986-08-20
US06/898,431 US4942156A (en) 1986-08-20 1986-08-20 Low molecular weight heparin derivatives having improved anti-Xa specificity
US06/898,124 US4745107A (en) 1986-08-20 1986-08-20 Heparin derivatives with improved permeability
US89812486 1986-08-20
US89813086 1986-08-20
US89843186 1986-08-20
US06/898,436 US4745106A (en) 1986-08-20 1986-08-20 Heparin derivatives having improved anti-Xa specificity
US06/898,130 US4745105A (en) 1986-08-20 1986-08-20 Low molecular weight heparin derivatives with improved permeability

Publications (3)

Publication Number Publication Date
DK434587D0 DK434587D0 (da) 1987-08-20
DK434587A true DK434587A (da) 1988-02-21
DK175087B1 DK175087B1 (da) 2004-05-24

Family

ID=27542290

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198704345A DK175087B1 (da) 1986-08-20 1987-08-20 Alkanoylestere af heparin, farmaceutisk præparat, der indeholder dem og anvendelse deraf

Country Status (8)

Country Link
EP (1) EP0256880B1 (da)
JP (1) JP2643950B2 (da)
AT (1) ATE122059T1 (da)
CA (1) CA1312861C (da)
DE (1) DE3751275T2 (da)
DK (1) DK175087B1 (da)
ES (1) ES2071608T3 (da)
NO (1) NO172803C (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3821271A1 (de) * 1988-06-23 1989-12-28 Solco Basel Ag Derivatisiertes heparin, verfahren zu dessen herstellung und arzneimittel, welches dieses enthaelt
US5011919A (en) * 1989-01-30 1991-04-30 Ajorca S.A. Modified heparins and obtention process
IT1243300B (it) * 1990-12-20 1994-05-26 Fidia Spa Derivati dell'eparina
IT1286510B1 (it) * 1996-11-29 1998-07-15 Cooperativa Centro Ricerche Po Esteri butirrici ad attivita' antiproliferativa e composizioni farmaceutiche che li contengono
JP4964577B2 (ja) * 2006-12-15 2012-07-04 有限会社応用糖質化学研究所 親脂質性ヘパリン修飾体、その製造方法及び毛髪成長促進剤
CN102516416A (zh) * 2011-12-28 2012-06-27 蚌埠医学院 一种肝素酯化物的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1355036A (en) * 1970-04-14 1974-06-05 Ici Ltd Articles of plastic film
JPS52111983A (en) * 1976-03-18 1977-09-20 Teijin Ltd Preparation of heparin derivatives
JPS55158055A (en) * 1979-05-25 1980-12-09 Teijin Ltd Preparation of antithrombus medical material
US4331697A (en) * 1980-09-02 1982-05-25 Teijin Limited Novel heparin derivative, method for production thereof, and method for rendering biomedical materials antithrombotic by use of the novel heparin derivative
CA1195322A (en) * 1982-07-19 1985-10-15 Eduardo Amaya Process for manufacturing low molecular weight heparins by depolymerization of normal heparin

Also Published As

Publication number Publication date
NO172803C (no) 1993-09-08
EP0256880A3 (en) 1988-12-14
NO172803B (no) 1993-06-01
CA1312861C (en) 1993-01-19
NO873501L (no) 1988-02-22
JP2643950B2 (ja) 1997-08-25
EP0256880B1 (en) 1995-05-03
DK175087B1 (da) 2004-05-24
DK434587D0 (da) 1987-08-20
NO873501D0 (no) 1987-08-19
ES2071608T3 (es) 1995-07-01
ATE122059T1 (de) 1995-05-15
DE3751275D1 (de) 1995-06-08
JPS6366202A (ja) 1988-03-24
DE3751275T2 (de) 1995-09-07
EP0256880A2 (en) 1988-02-24

Similar Documents

Publication Publication Date Title
DK210388D0 (da) Heparinderivater med lav molekylvaegt
DK24089D0 (da) Novel prodrug derivatives of biologically active agents containing hydroxyl groups or nh-acidic groups
EA200000376A1 (ru) Полимерные производные камптотецинов
FR2623809B1 (fr) Homologues et derives de (3s, 4s) hydroxy-7 delta-6-tetrahydrocannabinol
IT8948196A0 (it) Derivati di furano
DE3885670D1 (de) Veretherung von Polyoxyalkylenderivaten.
IT8848619A0 (it) Derivati di lisosfingolipidi
DK587986D0 (da) Konjugater af vinblastin eller derivater deraf, fremgangsmaade til fremstilling deraf og farmaceutiske praeparater indeholdende dem
DK434587D0 (da) Heparinderivater, farmaceutisk praeparat, der indeholder dem og anvendelsen af derivaterne
SE7808770L (sv) Pyrido(1,2-a)pyrimidinderivat jemte sett for deras framstellning och farmaceutiska beredningar innehallande dem
FR2496103B1 (fr) Nouveaux derives du benzopyranne et du benzothiopyranne, leur preparation et leur application comme medicaments
IT1187714B (it) Tenisoattivi derivati da idrossiacidi bicarbossilici
FR2540112B1 (fr) Nouveaux derives de la benzo(g)quinoleine, leur preparation et leur utilisation comme medicaments
IT8920929A0 (it) Nuovi derivati del r( ) 3 chinuclidinolo.
NZ233781A (en) (cyclic)phosphonyl-substituted guanine or adenine derivatives and pharmaceutical compositions
FR2640271B1 (fr) Nouveaux derives de l'adenosine, leur preparation et leur utilisation comme medicaments
IT8848618A0 (it) Derivati di lisogangliosidi
IT1208494B (it) Polimerizzazione. derivati solforati di chetoni aromatico-alifatici e alifatici come fotoiniziatori di
DE3789290D1 (de) Theophyllinmethyldithiolan und Theophyllinmethyldithianylderivate, ein Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Präparate.
DE69024193D1 (de) Ascorbinsäure-derivate
MD679F1 (en) Inclusion complex of N-ethoxycarbonyl-3-morpholinsydnonimine or salts thereof with cyclodextrin or its derivatives, preparation thereof and pharmaceutical compositions containing them, method of preparation thereof and treatment method
FR2636065B1 (fr) Nouveaux derives de dihydro-2,3 arylacoylaminoalcoyl-3 4h-benzoxazine-1,3 ones-4, leur preparation et leur application en tant que medicaments utiles en therapeutique
FR2637593B1 (fr) Nouveaux derives de la carbonyl-2 n,n(prime)-di-(trimethoxybenzoyle) piperazine, ainsi que leur procede de preparation
MX9203632A (es) Derivados de cicloalquiltiazol y composiciones farmaceuticas que los contienen.
FI892289A (fi) Substituerade azoltioetrar, deras framstaellning och deras anvaendning som skadedjursbekaempningsmedel.

Legal Events

Date Code Title Description
PUP Patent expired