DK426083A - Pteriner, fremgangsmaader til deres fremstilling samt deres anvendelse - Google Patents
Pteriner, fremgangsmaader til deres fremstilling samt deres anvendelse Download PDFInfo
- Publication number
- DK426083A DK426083A DK426083A DK426083A DK426083A DK 426083 A DK426083 A DK 426083A DK 426083 A DK426083 A DK 426083A DK 426083 A DK426083 A DK 426083A DK 426083 A DK426083 A DK 426083A
- Authority
- DK
- Denmark
- Prior art keywords
- pterines
- procedures
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/02—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
- C07D475/04—Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D475/00—Heterocyclic compounds containing pteridine ring systems
- C07D475/06—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
- C07D475/08—Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8226688 | 1982-09-20 | ||
GB838318833A GB8318833D0 (en) | 1983-07-12 | 1983-07-12 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
DK426083D0 DK426083D0 (da) | 1983-09-19 |
DK426083A true DK426083A (da) | 1984-03-21 |
Family
ID=26283872
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK426083A DK426083A (da) | 1982-09-20 | 1983-09-19 | Pteriner, fremgangsmaader til deres fremstilling samt deres anvendelse |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0108890B1 (fr) |
AU (1) | AU572792B2 (fr) |
CA (1) | CA1288099C (fr) |
DE (1) | DE3378634D1 (fr) |
DK (1) | DK426083A (fr) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5196533A (en) * | 1983-04-11 | 1993-03-23 | South Alabama Medical Science Foundation, Usa | Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines |
JPS61277618A (ja) * | 1985-06-04 | 1986-12-08 | Suntory Ltd | 自閉症治療剤 |
US5198547A (en) * | 1992-03-16 | 1993-03-30 | South Alabama Medical Science Foundation, Usa | Process for N5-formylating tetrahydropteridines |
GB9226377D0 (en) * | 1992-12-18 | 1993-02-10 | Babbedge Rachel C | Pharmaceutical compositions |
EP0674627A1 (fr) * | 1992-12-18 | 1995-10-04 | The Wellcome Foundation Limited | Derives de pyrimidine, de pyridine, de pteridinone et d'indazole utilises comme inhibiteurs enzymatiques |
DE4418096A1 (de) * | 1994-05-24 | 1995-11-30 | Cassella Ag | Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase |
JP4306825B2 (ja) | 1998-02-27 | 2009-08-05 | アスビオファーマ株式会社 | インスリン抵抗性が関与する血管機能異常を伴う疾患の予防または治療剤 |
DE69920757T2 (de) * | 1998-12-28 | 2005-12-15 | 4 AZA Bioscience N.V. | Immunosuppressive wirkungen von pteridinderivaten |
US7276506B2 (en) | 1998-12-28 | 2007-10-02 | 4 Aza Bioscience Nv | Immunosuppressive effects of pteridine derivatives |
EP3977999A1 (fr) * | 2003-11-17 | 2022-04-06 | BioMarin Pharmaceutical Inc. | Traitement de la phénylcétonurie avec bh4 |
AU2005306686B2 (en) | 2004-11-17 | 2011-06-02 | Biomarin Pharmaceutical Inc. | Stable tablet formulation of tetrahydrobiopterin |
WO2008009078A2 (fr) | 2006-07-20 | 2008-01-24 | Gilead Sciences, Inc. | Dérivés de la quinazoline tri-substitués en 4,6-dl et en 2,4,6 utilisables pour traiter les infections virales |
US10144736B2 (en) | 2006-07-20 | 2018-12-04 | Gilead Sciences, Inc. | Substituted pteridines useful for the treatment and prevention of viral infections |
EA035093B1 (ru) | 2015-03-04 | 2020-04-27 | Джилид Сайэнс, Инк. | 4,6-диаминопиридо[3,2-d]пиримидиновые соединения, модулирующие toll-подобные рецепторы |
ES2906581T3 (es) | 2016-09-02 | 2022-04-19 | Gilead Sciences Inc | Compuestos moduladores de los receptores tipo Toll |
ES2826748T3 (es) | 2016-09-02 | 2021-05-19 | Gilead Sciences Inc | Derivados de 4,6-diamino-pirido[3,2-d]pirimidina como moduladores de receptores de tipo Toll |
TW202210480A (zh) | 2019-04-17 | 2022-03-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TWI751517B (zh) | 2019-04-17 | 2022-01-01 | 美商基利科學股份有限公司 | 類鐸受體調節劑之固體形式 |
TW202115056A (zh) | 2019-06-28 | 2021-04-16 | 美商基利科學股份有限公司 | 類鐸受體調節劑化合物的製備方法 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1293541A (en) * | 1969-03-18 | 1972-10-18 | John Alexander Blair | Folic acid derivatives |
BE787236A (fr) * | 1971-08-05 | 1973-02-05 | Wellcome Found | Compositions de potentialisation |
JPS5883691A (ja) * | 1981-11-13 | 1983-05-19 | Kanegafuchi Chem Ind Co Ltd | 1′,2′−ジアシル−(6r,s)−5,6,7,8−テトラヒドロ−l−ビオプテリンおよびその製法 |
-
1983
- 1983-09-19 EP EP83109291A patent/EP0108890B1/fr not_active Expired
- 1983-09-19 AU AU19256/83A patent/AU572792B2/en not_active Expired
- 1983-09-19 DK DK426083A patent/DK426083A/da not_active Application Discontinuation
- 1983-09-19 DE DE8383109291T patent/DE3378634D1/de not_active Expired
- 1983-09-20 CA CA000437101A patent/CA1288099C/fr not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0108890A2 (fr) | 1984-05-23 |
DK426083D0 (da) | 1983-09-19 |
EP0108890A3 (en) | 1985-10-02 |
CA1288099C (fr) | 1991-08-27 |
AU1925683A (en) | 1984-03-29 |
EP0108890B1 (fr) | 1988-12-07 |
DE3378634D1 (en) | 1989-01-12 |
AU572792B2 (en) | 1988-05-19 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |