DK426083D0 - Pteriner, fremgangsmader til deres fremstilling samt deres anvendelse - Google Patents

Pteriner, fremgangsmader til deres fremstilling samt deres anvendelse

Info

Publication number
DK426083D0
DK426083D0 DK426083A DK426083A DK426083D0 DK 426083 D0 DK426083 D0 DK 426083D0 DK 426083 A DK426083 A DK 426083A DK 426083 A DK426083 A DK 426083A DK 426083 D0 DK426083 D0 DK 426083D0
Authority
DK
Denmark
Prior art keywords
pterines
procedures
manufacturing
Prior art date
Application number
DK426083A
Other languages
English (en)
Other versions
DK426083A (da
Inventor
Charles Adam Nichol
Jr John Frederick Reinhard
Cary Keith Smith
Eric Cleveland Bigham
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838318833A external-priority patent/GB8318833D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of DK426083D0 publication Critical patent/DK426083D0/da
Publication of DK426083A publication Critical patent/DK426083A/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/02Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4
    • C07D475/04Heterocyclic compounds containing pteridine ring systems with an oxygen atom directly attached in position 4 with a nitrogen atom directly attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D241/26Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D475/00Heterocyclic compounds containing pteridine ring systems
    • C07D475/06Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4
    • C07D475/08Heterocyclic compounds containing pteridine ring systems with a nitrogen atom directly attached in position 4 with a nitrogen atom directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK426083A 1982-09-20 1983-09-19 Pteriner, fremgangsmaader til deres fremstilling samt deres anvendelse DK426083A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8226688 1982-09-20
GB838318833A GB8318833D0 (en) 1983-07-12 1983-07-12 Chemical compounds

Publications (2)

Publication Number Publication Date
DK426083D0 true DK426083D0 (da) 1983-09-19
DK426083A DK426083A (da) 1984-03-21

Family

ID=26283872

Family Applications (1)

Application Number Title Priority Date Filing Date
DK426083A DK426083A (da) 1982-09-20 1983-09-19 Pteriner, fremgangsmaader til deres fremstilling samt deres anvendelse

Country Status (5)

Country Link
EP (1) EP0108890B1 (da)
AU (1) AU572792B2 (da)
CA (1) CA1288099C (da)
DE (1) DE3378634D1 (da)
DK (1) DK426083A (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196533A (en) * 1983-04-11 1993-03-23 South Alabama Medical Science Foundation, Usa Cyclization of 5 amino-pyrimidines to quinoid 6,6 disubstituted dihydropteridines
JPS61277618A (ja) * 1985-06-04 1986-12-08 Suntory Ltd 自閉症治療剤
US5198547A (en) * 1992-03-16 1993-03-30 South Alabama Medical Science Foundation, Usa Process for N5-formylating tetrahydropteridines
GB9226377D0 (en) * 1992-12-18 1993-02-10 Babbedge Rachel C Pharmaceutical compositions
JPH08504798A (ja) * 1992-12-18 1996-05-21 ザ ウエルカム ファウンデーション リミテッド 酵素阻害薬としての,ピリミジン,ピリジン,プテリジノンおよびインダゾール誘導体
DE4418096A1 (de) * 1994-05-24 1995-11-30 Cassella Ag Verwendung von Pteridin-Derivaten als Hemmstoffe der NO-Synthase
JP4306825B2 (ja) 1998-02-27 2009-08-05 アスビオファーマ株式会社 インスリン抵抗性が関与する血管機能異常を伴う疾患の予防または治療剤
US7276506B2 (en) 1998-12-28 2007-10-02 4 Aza Bioscience Nv Immunosuppressive effects of pteridine derivatives
JP2002533464A (ja) * 1998-12-28 2002-10-08 カー・イュー・ルーベン・リサーチ・アンド・ディベロップメント プテリジン誘導体の免疫抑制作用
SI3138566T1 (sl) 2003-11-17 2022-04-29 Biomarin Pharmaceutical Inc. Postopki in sestavki za zdravljenje presnovnih motenj
JP2008520574A (ja) 2004-11-17 2008-06-19 バイオマリン ファーマシューティカル インコーポレイテッド テトラヒドロビオプテリンの安定性錠剤処方物
WO2008009079A2 (en) 2006-07-20 2008-01-24 Gilead Sciences, Inc. Substituted pteridines useful for the treatment and prevention of viral infections
HUE050029T2 (hu) 2015-03-04 2020-11-30 Gilead Sciences Inc 4,6-Diamino-pirido[3,2-d]pirimidin-származékok és alkalmazásuk toll-szerû receptorok modulátoraként
WO2018045150A1 (en) 2016-09-02 2018-03-08 Gilead Sciences, Inc. 4,6-diamino-pyrido[3,2-d]pyrimidine derivaties as toll like receptor modulators
JP6746776B2 (ja) 2016-09-02 2020-08-26 ギリアード サイエンシーズ, インコーポレイテッド Toll様受容体調節剤化合物
TWI751517B (zh) 2019-04-17 2022-01-01 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202210480A (zh) 2019-04-17 2022-03-16 美商基利科學股份有限公司 類鐸受體調節劑之固體形式
TW202115056A (zh) 2019-06-28 2021-04-16 美商基利科學股份有限公司 類鐸受體調節劑化合物的製備方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293541A (en) * 1969-03-18 1972-10-18 John Alexander Blair Folic acid derivatives
BE787236A (fr) * 1971-08-05 1973-02-05 Wellcome Found Compositions de potentialisation
JPS5883691A (ja) * 1981-11-13 1983-05-19 Kanegafuchi Chem Ind Co Ltd 1′,2′−ジアシル−(6r,s)−5,6,7,8−テトラヒドロ−l−ビオプテリンおよびその製法

Also Published As

Publication number Publication date
DE3378634D1 (en) 1989-01-12
DK426083A (da) 1984-03-21
CA1288099C (en) 1991-08-27
EP0108890B1 (en) 1988-12-07
AU572792B2 (en) 1988-05-19
AU1925683A (en) 1984-03-29
EP0108890A3 (en) 1985-10-02
EP0108890A2 (en) 1984-05-23

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Legal Events

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AHS Application shelved for other reasons than non-payment